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EP About this file: EP2888367

EP2888367 - SCREENING AND ENGINEERING METHOD OF SUPER-STABLE IMMUNOGLOBULIN VARIABLE DOMAINS AND THEIR USES [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 05.03.2021 Database last updated on 02.11.2024
Former	The patent has been granted Status updated on 27.03.2020
Former	Grant of patent is intended Status updated on 12.11.2019
Former	Examination is in progress Status updated on 12.05.2017
Most recent event Tooltip	08.07.2022	Lapse of the patent in a contracting state New state(s): MK	published on 10.08.2022 [2022/32]
Applicant(s)	For all designated states Mogam Biotechnology Research Institute 341 Pojung-Dong Giheung-Gu Yongin-Si, Gyeonggi-do 446-799 / KR
	[2020/17]
Former [2019/50]	For all designated states Mogam Biotechnology Research Institute 341 Pojung-Dong Giheung-Gu Yongin-Si Kyunggi-do 446-799 / KR
Former [2015/27]	For all designated states Mogam Biotechnology Research Institute 341 Bojeong-dong Giheung-gu Gyeonggi do, Yongin-si 446-799 / KR
Inventor(s)	01 / LIM, Hyung-Kwon 341 Pojung-Dong Giheung-Gu Yongin-Si Gyeonggi-do 446-799 / KR
	02 / KIM, Sung Geun 341 Pojung-Dong Giheung-Gu Yongin-Si Gyeonggi-do 446-799 / KR
	03 / PARK, Young Seoub 341 Pojung-Dong Giheung-Gu Yongin-Si Gyeonggi-do 446-799 / KR
	04 / NAM, Hyo Jung 341 Pojung-Dong Giheung-Gu Yongin-Si Gyeonggi-do 446-799 / KR
	05 / KIM, Dong-Sik 341 Pojung-Dong Giheung-Gu Yongin-Si Gyeonggi-do 446-799 / KR
	06 / PARK, Jae Chan 341 Pojung-Dong Giheung-Gu Yongin-Si Gyeonggi-do 446-799 / KR
	07 / YOON, Yeup 341 Pojung-Dong Giheung-Gu Yongin-Si Gyeonggi-do 446-799 / KR
	[2015/27]
Representative(s)	Goddar, Heinz J. Boehmert & Boehmert Anwaltspartnerschaft mbB Pettenkoferstrasse 22 80336 München / DE
	[2020/18]
Former [2015/27]	Goddar, Heinz J. Boehmert & Boehmert Anwaltspartnerschaft mbB Patentanwälte Rechtsanwälte Pettenkoferstrasse 20-22 80336 München / DE
Application number, filing date	12883278.9	22.08.2012
	[2020/18]
	WO2012KR06680
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2014030780
	Date:	27.02.2014
	Language:	EN
	[2014/09]
	Type:	A1 Application with search report
	No.:	EP2888367
	Date:	01.07.2015
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 27.02.2014 takes the place of the publication of the European patent application.
	[2015/27]
	Type:	B1 Patent specification
	No.:	EP2888367
	Date:	29.04.2020
	Language:	EN
	[2020/18]
Search report(s)	International search report - published on:	KR	27.02.2014
	(Supplementary) European search report - dispatched on:	EP	18.03.2016
Classification	IPC:	C12N15/62, C12N15/63, C07K19/00, C12N15/13, C07K16/28, G01N33/53	[2015/27]
	CPC:	C07K16/00 (EP,CN,KR,US); C12N15/62 (KR); G01N33/6857 (KR,US); C07K16/18 (EP,CN,KR,US); C07K16/32 (EP,CN,KR,US); C07K19/00 (KR); (+) C12N15/63 (KR); G01N33/53 (KR); C07K2317/21 (EP,CN,KR,US); C07K2317/56 (US); C07K2317/565 (US); C07K2317/569 (EP,US); C07K2317/94 (EP,CN,KR,US); C07K2319/00 (EP,CN,US); C07K2319/10 (EP,CN,US); C40B40/10 (US); G01N2500/00 (EP,KR,US) (-)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/27]
Extension states	BA	Not yet paid
	ME	Not yet paid
Title	German:	SCREENING- UND MANIPULATIONSVERFAHREN FÜR SUPERSTABILE IMMUNGLOBULIN-VERÄNDERLICHE DOMÄNEN UND VERWENDUNGEN DAVON	[2015/27]
	English:	SCREENING AND ENGINEERING METHOD OF SUPER-STABLE IMMUNOGLOBULIN VARIABLE DOMAINS AND THEIR USES	[2015/27]
	French:	PROCÉDÉ DE CRIBLAGE ET DE FABRICATION DE DOMAINES VARIABLES D'IMMUNOGLOBULINES SUPER-STABLES ET APPLICATIONS ASSOCIÉES	[2015/27]
Entry into regional phase	16.03.2015	National basic fee paid
	16.03.2015	Search fee paid
	16.03.2015	Designation fee(s) paid
	16.03.2015	Examination fee paid
Examination procedure	16.03.2015	Examination requested [2015/27]
	29.09.2016	Amendment by applicant (claims and/or description)
	16.05.2017	Despatch of a communication from the examining division (Time limit: M04)
	11.09.2017	Reply to a communication from the examining division
	25.01.2018	Despatch of a communication from the examining division (Time limit: M04)
	22.05.2018	Reply to a communication from the examining division
	16.08.2018	Despatch of a communication from the examining division (Time limit: M04)
	21.12.2018	Reply to a communication from the examining division
	28.05.2019	Despatch of a communication from the examining division (Time limit: M01)
	07.06.2019	Reply to a communication from the examining division
	13.11.2019	Communication of intention to grant the patent
	13.03.2020	Fee for grant paid
	13.03.2020	Fee for publishing/printing paid
	13.03.2020	Receipt of the translation of the claim(s)
Divisional application(s)	EP16202979.7 / EP3165535
	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 16.05.2017
Opposition(s)	01.02.2021	No opposition filed within time limit [2021/14]
Fees paid	Renewal fee
	16.03.2015	Renewal fee patent year 03
	10.08.2015	Renewal fee patent year 04
	11.08.2016	Renewal fee patent year 05
	14.08.2017	Renewal fee patent year 06
	28.08.2018	Renewal fee patent year 07
	30.08.2019	Renewal fee patent year 08
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	22.08.2012
	AL	29.04.2020
	AT	29.04.2020
	CY	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	MK	29.04.2020
	MT	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SI	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	TR	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IE	22.08.2020
	LU	22.08.2020
	IS	29.08.2020
	BE	31.08.2020
	CH	31.08.2020
	LI	31.08.2020
	PT	31.08.2020
	[2022/32]
Former [2022/27]	HU	22.08.2012
	AL	29.04.2020
	AT	29.04.2020
	CY	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	MT	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SI	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	TR	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IE	22.08.2020
	LU	22.08.2020
	IS	29.08.2020
	BE	31.08.2020
	CH	31.08.2020
	LI	31.08.2020
	PT	31.08.2020
Former [2022/26]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SI	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	TR	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IE	22.08.2020
	LU	22.08.2020
	IS	29.08.2020
	BE	31.08.2020
	CH	31.08.2020
	LI	31.08.2020
	PT	31.08.2020
Former [2021/37]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SI	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IE	22.08.2020
	LU	22.08.2020
	IS	29.08.2020
	BE	31.08.2020
	CH	31.08.2020
	LI	31.08.2020
	PT	31.08.2020
Former [2021/36]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SI	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	LU	22.08.2020
	IS	29.08.2020
	BE	31.08.2020
	CH	31.08.2020
	LI	31.08.2020
	PT	31.08.2020
Former [2021/24]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SI	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	LU	22.08.2020
	IS	29.08.2020
	CH	31.08.2020
	LI	31.08.2020
	PT	31.08.2020
Former [2021/20]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	LU	22.08.2020
	IS	29.08.2020
	CH	31.08.2020
	LI	31.08.2020
	PT	31.08.2020
Former [2021/18]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	MC	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2021/10]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	NL	29.04.2020
	PL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SK	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2021/09]	AL	29.04.2020
	AT	29.04.2020
	CZ	29.04.2020
	DK	29.04.2020
	EE	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	IT	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	NL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2021/08]	AL	29.04.2020
	DK	29.04.2020
	ES	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	NL	29.04.2020
	RO	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	SM	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2021/04]	AL	29.04.2020
	FI	29.04.2020
	HR	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	NL	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2021/01]	FI	29.04.2020
	HR	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	BG	29.07.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2020/51]	FI	29.04.2020
	HR	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	RS	29.04.2020
	SE	29.04.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2020/50]	FI	29.04.2020
	HR	29.04.2020
	LT	29.04.2020
	LV	29.04.2020
	SE	29.04.2020
	NO	29.07.2020
	GR	30.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2020/48]	FI	29.04.2020
	LT	29.04.2020
	SE	29.04.2020
	NO	29.07.2020
	IS	29.08.2020
	PT	31.08.2020
Former [2020/47]	LT	29.04.2020
	NO	29.07.2020
	IS	29.08.2020
Former [2020/46]	IS	29.08.2020
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		[X]US2005054001 (MUYLDERMANS SERGE [BE]) [X] 14-17 * example 5 *;
		[XI]WO2005032460 (CENTOCOR INC [US], et al) [X] 11-13 * sequence 33 * [I] 14-17;
		[XI]WO2006026759 (GENENTECH INC [US], et al) [X] 11-13 * sequence 52 * [I] 14-17;
		[X]WO2012100343 (CA NAT RESEARCH COUNCIL [CA], et al) [X] 14-17 * example 10 *;
		[XI] - AUF DER MAUR A ET AL, "Antigen-independent selection of intracellular stable antibody frameworks", METHODS, ACADEMIC PRESS, US, (20041001), vol. 34, no. 2, doi:10.1016/J.YMETH.2004.04.004, ISSN 1046-2023, pages 215 - 224, XP004526807 [X] 11-13 * abstract * [I] 14-17 DOI: http://dx.doi.org/10.1016/j.ymeth.2004.04.004
		[I] - WORN A ET AL, "Stability engineering of antibody single-chain Fv fragments", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (20010202), vol. 305, no. 5, doi:10.1006/JMBI.2000.4265, ISSN 0022-2836, pages 989 - 1010, XP004465987 [I] 11-17 * page 998, column l, paragraph 1 * * page 999, column l, paragraph 3 * DOI: http://dx.doi.org/10.1006/jmbi.2000.4265
		[A] - EWERT S ET AL, "Biophysical Properties of Human Antibody Variable Domains", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, vol. 325, no. 3, doi:10.1016/S0022-2836(02)01237-8, ISSN 0022-2836, (20030117), pages 531 - 553, (20030117), XP027180832 [A] 1-17 * the whole document * DOI: http://dx.doi.org/10.1016/S0022-2836(02)01237-8
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	by applicant	KR960007784B
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