blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2650360

EP2650360 - Endocrine precursor cells, pancreatic hormone-expressing cells and methods of production [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.07.2020
Database last updated on 18.09.2024
FormerThe patent has been granted
Status updated on  21.06.2019
FormerGrant of patent is intended
Status updated on  31.01.2019
FormerExamination is in progress
Status updated on  09.12.2016
Most recent event   Tooltip24.06.2022Lapse of the patent in a contracting state
New state(s): CY, HU, MT
published on 27.07.2022  [2022/30]
Applicant(s)For all designated states
VIACYTE, INC.
3550 General Atomics Court Building No 2-503
San Diego, CA 92121 / US
[2019/30]
Former [2013/42]For all designated states
VIACYTE, INC.
3550 General Atomics Court Building No 2-503
San Diego, CA 92121 / US
Inventor(s)01 / D'Amour, Kevin
2739 East Evans Road
San Diego, CA 92106 / US
02 / Bang, Anne
4273 Calle Isabelino
San Diego, CA 92130 / US
03 / Baetge, Emmanuel E.
308 Sunset Drive
92024 Encinitas, CA / US
 [2019/29]
Former [2013/42]01 / D'Amour, Kevin
2739 East Evans Road
San Diego, CA 92106 / US
02 / Bang, Anne
4273 Calle Isabelino
San Diego, CA 92130 / US
03 / Baetge, Emmanuel E.
Ch. des Grandes Vignes 12
1025 St Sulpice / CH
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2019/30]
Former [2013/42]Lord, Hilton David, et al
Marks & Clerk LLP
90 Long Acre
London
WC2E 9RA / GB
Application number, filing date13159719.702.03.2007
[2013/42]
Priority number, dateUS20060778649P02.03.2006         Original published format: US 778649 P
US20060833633P26.07.2006         Original published format: US 833633 P
US20060852878P18.10.2006         Original published format: US 852878 P
[2013/42]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2650360
Date:16.10.2013
Language:EN
[2013/42]
Type: A3 Search report 
No.:EP2650360
Date:12.02.2014
Language:EN
[2014/07]
Type: B1 Patent specification 
No.:EP2650360
Date:24.07.2019
Language:EN
[2019/30]
Search report(s)(Supplementary) European search report - dispatched on:EP10.01.2014
ClassificationIPC:C12N5/071, C12N5/0735
[2013/42]
CPC:
C12N5/0676 (EP,US); A61K35/39 (US); A61P1/18 (EP);
A61P3/10 (EP); A61P5/48 (EP); C12N5/0678 (EP,US);
C12N2500/38 (EP,US); C12N2501/10 (EP,US); C12N2501/105 (EP,US);
C12N2501/115 (EP,US); C12N2501/119 (EP,US); C12N2501/12 (EP,US);
C12N2501/15 (US); C12N2501/16 (EP,US); C12N2501/33 (EP,US);
C12N2501/335 (US); C12N2501/385 (EP,US); C12N2501/41 (EP,US);
C12N2501/415 (EP,US); C12N2501/42 (EP,US); C12N2501/58 (EP,US);
C12N2501/734 (US); C12N2501/999 (EP,US); C12N2506/02 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2019/30]
Former [2013/42]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Endokrine Vorläuferzellen, pankreashormon-exprimierende Zellen und Herstellungsverfahren[2013/42]
English:Endocrine precursor cells, pancreatic hormone-expressing cells and methods of production[2013/42]
French:Cellules précurseurs endocrines, cellules exprimant des hormones pancréatiques et procédés de production[2013/42]
Examination procedure12.08.2014Amendment by applicant (claims and/or description)
12.08.2014Examination requested  [2014/38]
13.12.2016Despatch of a communication from the examining division (Time limit: M06)
23.06.2017Reply to a communication from the examining division
08.01.2019Cancellation of oral proceeding that was planned for 21.01.2019
21.01.2019Date of oral proceedings (cancelled)
01.02.2019Communication of intention to grant the patent
11.06.2019Fee for grant paid
11.06.2019Fee for publishing/printing paid
11.06.2019Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP07752255.5  / EP1999253
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20070752255) is  08.03.2011
Opposition(s)03.06.2020No opposition filed within time limit [2020/33]
Fees paidRenewal fee
12.06.2013Renewal fee patent year 03
12.06.2013Renewal fee patent year 04
12.06.2013Renewal fee patent year 05
12.06.2013Renewal fee patent year 06
12.06.2013Renewal fee patent year 07
27.03.2014Renewal fee patent year 08
27.03.2015Renewal fee patent year 09
31.03.2016Renewal fee patent year 10
27.03.2017Renewal fee patent year 11
27.03.2018Renewal fee patent year 12
27.03.2019Renewal fee patent year 13
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU02.03.2007
AT24.07.2019
CY24.07.2019
CZ24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
MC24.07.2019
MT24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
SI24.07.2019
SK24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
IE02.03.2020
LU02.03.2020
[2022/27]
Former [2021/08]AT24.07.2019
CZ24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
MC24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
SI24.07.2019
SK24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
IE02.03.2020
LU02.03.2020
Former [2021/04]AT24.07.2019
CZ24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
MC24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
SI24.07.2019
SK24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
LU02.03.2020
Former [2020/49]AT24.07.2019
CZ24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
MC24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
SI24.07.2019
SK24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
Former [2020/37]AT24.07.2019
CZ24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
SI24.07.2019
SK24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
Former [2020/36]AT24.07.2019
CZ24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
SK24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
Former [2020/25]AT24.07.2019
CZ24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
SK24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
PT25.11.2019
IS24.02.2020
Former [2020/24]AT24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
PT25.11.2019
IS24.02.2020
Former [2020/23]AT24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
IT24.07.2019
LT24.07.2019
LV24.07.2019
PL24.07.2019
RO24.07.2019
SE24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
Former [2020/22]AT24.07.2019
EE24.07.2019
ES24.07.2019
FI24.07.2019
LT24.07.2019
LV24.07.2019
SE24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
Former [2020/17]AT24.07.2019
ES24.07.2019
FI24.07.2019
LT24.07.2019
LV24.07.2019
SE24.07.2019
TR24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
Former [2020/12]AT24.07.2019
ES24.07.2019
FI24.07.2019
LT24.07.2019
LV24.07.2019
SE24.07.2019
BG24.10.2019
GR25.10.2019
IS24.11.2019
PT25.11.2019
Former [2020/11]AT24.07.2019
ES24.07.2019
FI24.07.2019
LT24.07.2019
LV24.07.2019
SE24.07.2019
BG24.10.2019
GR25.10.2019
PT25.11.2019
Former [2020/10]AT24.07.2019
FI24.07.2019
LT24.07.2019
SE24.07.2019
BG24.10.2019
PT25.11.2019
Former [2020/09]FI24.07.2019
LT24.07.2019
Former [2020/08]LT24.07.2019
Documents cited:Search[XI]WO03050249  (GERON CORP [US], et al) [X] 1,4,5,7,8,10-13 * examples 3-6 * * page 17, paragraph 3 * [I] 2,3,6,9;
 [AD]WO2005116073  (NOVOCELL INC [US], et al) [AD] 1-13 * the whole document *;
 [XP]WO2006083782  (ES CELL INT PTE LTD [SG], et al) [XP] 8,10-12 * page 64 - page 66; figures 18,19,23; example 11 *;
 [XI]  - SEGEV HANNA ET AL, "Differentiation of human embryonic stem cells into insulin-producing clusters.", STEM CELLS (DAYTON, OHIO) 2004, (2004), vol. 22, no. 3, ISSN 1066-5099, pages 265 - 274, XP009038283 [X] 1-5,8-12 * figure 2 * * figure 3 * * page 269, column R, paragraph 2 - page 270, column R, paragraph 1 * * page 269, column L, paragraph 3 * [I] 6,13

DOI:   http://dx.doi.org/10.1634/stemcells.22-3-265
 [A]  - SHI YAN ET AL, "Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid.", STEM CELLS (DAYTON, OHIO) MAY 2005, (200505), vol. 23, no. 5, ISSN 1066-5099, pages 656 - 662, XP008059753 [A] 1-13 * figure 1 *

DOI:   http://dx.doi.org/10.1634/stemcells.2004-0241
 [A]  - MURTAUGH L CHARLES ET AL, "Notch signaling controls multiple steps of pancreatic differentiation.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 9 DEC 2003, (20031209), vol. 100, no. 25, ISSN 0027-8424, pages 14920 - 14925, XP002452671 [A] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.2436557100
 [XP]  - D'AMOUR KEVIN A ET AL, "Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.", NATURE BIOTECHNOLOGY NOV 2006, (200611), vol. 24, no. 11, ISSN 1087-0156, pages 1392 - 1401, XP002423119 [XP] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt1259
 [XP]  - MADSEN O D ET AL, "Towards cell therapy for diabetes", NATURE BIOTECHNOLOGY 2006 UNITED STATES, (2006), vol. 24, no. 12, pages 1481 - 1483, XP002452672 [XP] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt1206-1481
ExaminationWO03046141
    - CARPENTER M K ET AL, "Enrichment of neurons and neural precursors from human embryonic stem cells.", EXPERIMENTAL NEUROLOGY DEC 2001, (200112), vol. 172, no. 2, ISSN 0014-4886, pages 383 - 397
    - DEVASKAR S U ET AL, "Insulin gene expression and insulin synthesis in mammalian neuronal cells.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 18 MAR 1994, (19940318), vol. 269, no. 11, ISSN 0021-9258, pages 8445 - 8454
    - GANNON M ET AL, "Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas.", GENESIS (NEW YORK, N.Y. : 2000) FEB 2000, (200002), vol. 26, no. 2, ISSN 1526-954X, pages 139 - 142
    - HORI YUICHI ET AL, "Differentiation of insulin-producing cells from human neural progenitor cells.", PLOS MEDICINE APR 2005, (200504), vol. 2, no. 4, ISSN 1549-1676, page e103
    - DOTTORI MIRELLA ET AL, "Neural differentiation of human embryonic stem cells.", METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.) 2008, (2008), vol. 438, ISSN 1064-3745, pages 19 - 30
    - DRUCKER D J ET AL, "Glucagon gene expression in vertebrate brain.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 25 SEP 1988, (19880925), vol. 263, no. 27, ISSN 0021-9258, pages 13475 - 13478
    - FRANCESCO PANZA ET AL, "REVIEW: [gamma]-Secretase Inhibitors for the Treatment of Alzheimer's Disease: The Current State : Secretase-Based Drugs in Alzheimer's Disease", CNS NEUROSCIENCE & THERAPEUTICS, GB, (20101001), vol. 16, no. 5, doi:10.1111/j.1755-5949.2010.00164.x, ISSN 1755-5930, pages 272 - 284, XP055470265

DOI:   http://dx.doi.org/10.1111/j.1755-5949.2010.00164.x
by applicantUS5453357
 US5670372
 US5690926
 US5843780
 US6090622
 US6200806
 US6251671
 US2002072117
 US2003175956
 US2003190748
 US2004229350
    - D'AMOUR ET AL., NAT. BIOTECH., (2005), vol. 23, pages 1534 - 1541
    - BOCIAN-SOBKOWSKA, J. ET AL., HISTOCHEM.CELL BIOL., (1999), vol. 112, pages 147 - 153
    - RAHIER J. ET AL., CELL TISSUE RES., (1979), vol. 200, no. 3, pages 359 - 366
    - MALAISSE-LANGAE F. ET AL., DIABETOLOGIA, (1979), vol. 17, no. 6, pages 361 - 365
    - FIOCCA R. ET AL., HISTOCHEMISTRY, (1983), vol. 77, no. 4, pages 511 - 523
    - STEFAN Y. ET AL., DIABETOLOGICA, (1982), vol. 23, no. 2, pages 141 - 142
    - KELLY, O.G.; MELTON, D. A., DEV. DYN., (2000), vol. 218, pages 615 - 627
    - CHEN, Y. ET AL., DEV. BIOL., (2004), vol. 271, no. 1, pages 144 - 160
    - FIELD, H.A. ET AL., DEV. BIOL., (2003), vol. 263, pages 197 - 208
    - SPOONER, B.S. ET AL., J. CELL BIOLOGY, (1970), vol. 47, no. 23, pages 5 - 246
    - LI, H. ET AL., NATURE, (1999), vol. 23, pages 67 - 70
    - RONN, L., EUR J NEUROSCI., (2002), vol. 16, pages 1720 - 30
    - SRIKANTA ET AL., ENDOCRINOLOGY, (1987), vol. 120, pages 2240 - 2244
    - D'AMOUR, K. ET AL., NATURE BIOTECHNOLOGY, (2005), vol. 23, pages 1534 - 1541
    - D'AMOUR, K. ET AL., NATURE BIOTECHNOLOG, (2005), vol. 23, pages 1534 - 1541
    - D'AMOUR, K., NATURE BIOTECHNOLOGY, (2005), vol. 23, pages 1534 - 1541
    - D'AMOUR, K ET AL., NATURE BIOTECHNOLOGY, (2005), vol. 23, pages 1534 - 1541
    - D'AMOUR, K. ET AL., NATURE BIOTECHNOLOGY, (2005), vol. 2, no. 3, pages 1534 - 1541
    - JOANNIDES ET AL., STEM CELLS, (2006), vol. 24, pages 230 - 235
    - BOCIAN-SOBKOWSKA, J. ET AL., HISTOCHEM. CELL BIOL., (1999), vol. 112, pages 147 - 153
    - SPOONER, B.S. ET AL., J. CELL BIOLOGY, (1970), vol. 47, pages 235 - 246
    - STAFFORD, D.; PRINCE, CURR. BIOL., (2002), vol. 12, pages 1 - 20
    - MORIYA, N. ET AL., DEVELOP. GROWTH DIFFER., (2000), vol. 42, pages 175 - 185
    - CHEN, Y., DEV. BIOL., (2004), vol. 271, pages 144 - 160
    - STAFFORD, D. ET AL., DEVELOPMENT, (2006), vol. 133, no. 5, pages 949 - 956
    - MOLOTKOV, A., DEVEL. DYN., (2005), vol. 232, pages 950 - 957
    - GAO, R. ET AL., DIABELTOLOGIA, (2005), vol. 48, pages 2296 - 2304
    - RONN, L. ET AL., EUR J NEUROSCI., (2002), vol. 16, no. 9, pages 1720 - 30
 US20040021618
 US20050165305
 US20050730917
 US20050736598
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.