EP2666777 - Certain chemical entities having an imidazo<4,5-b>pyrazin-2(3H)-one core, compositions and methods [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 24.10.2014 Database last updated on 31.08.2024 | Most recent event Tooltip | 24.10.2014 | Application deemed to be withdrawn | published on 26.11.2014 [2014/48] | Applicant(s) | For all designated states Cytokinetics, Inc. 280 East Grand Avenue South San Francisco, CA 94080 / US | [2013/48] | Inventor(s) | 01 /
Muci, Alex 2025 Stockton Street, 3 San Francisco, CA California 94133 / US | 02 /
Finer, Jeffrey T. 717 Gateshead Ct. Foster City, CA California 94404 / US | 03 /
Lu, Pu-Ping 638 Pilgrim Drive Foster City, CA California 94404 / US | 04 /
Russell, Alan James 44 Lundys Lane San Francsico, CA California 94110 / US | 05 /
Morgan, Bradley P. 1206 Rimer Drive Moraga, CA California 94556 / US | 06 /
Morgans, David J., Jr. 781 Vista Grande Avenue Los Altos, CA California 94024 / US | [2013/48] | Representative(s) | Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [2013/48] | Application number, filing date | 13176575.2 | 01.08.2007 | [2013/48] | Priority number, date | US20060835272P | 02.08.2006 Original published format: US 835272 P | US20070921054P | 30.03.2007 Original published format: US 921054 P | [2013/48] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2666777 | Date: | 27.11.2013 | Language: | EN | [2013/48] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 24.10.2013 | Classification | IPC: | C07D487/04, A61K31/498, A61P19/08, A61P21/04 | [2013/48] | CPC: |
C07D487/04 (EP,KR,US);
A61K31/498 (KR);
A61P1/14 (EP);
A61P11/00 (EP);
A61P19/00 (EP);
A61P19/08 (EP);
A61P21/00 (EP);
A61P21/02 (EP);
A61P21/04 (EP);
A61P21/06 (EP);
A61P25/00 (EP);
A61P25/08 (EP);
A61P3/00 (EP);
A61P3/04 (EP);
A61P35/00 (EP);
A61P43/00 (EP)
(-)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR [2013/48] | Extension states | AL | 19.05.2014 | BA | 19.05.2014 | HR | 19.05.2014 | MK | 19.05.2014 | RS | 19.05.2014 | Title | German: | Bestimmte chemische Stoffe mit eine imidazo<4,5-b>pyrazin-2(3H)-one Kernstruktur, Zusammensetzungen und Verfahren | [2013/48] | English: | Certain chemical entities having an imidazo<4,5-b>pyrazin-2(3H)-one core, compositions and methods | [2013/48] | French: | Certaines entités chimiques avec un noyeau imidazo<4,5-b>pyrazin-2(3H)-one, compositions et procédés | [2013/48] | Examination procedure | 19.05.2014 | Examination requested [2014/26] | 28.05.2014 | Application deemed to be withdrawn, date of legal effect [2014/48] | 03.07.2014 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time [2014/48] | Parent application(s) Tooltip | EP07810993.1 / EP2069352 | Fees paid | Renewal fee | 15.07.2013 | Renewal fee patent year 03 | 15.07.2013 | Renewal fee patent year 04 | 15.07.2013 | Renewal fee patent year 05 | 15.07.2013 | Renewal fee patent year 06 | 15.07.2013 | Renewal fee patent year 07 | Penalty fee | Additional fee for renewal fee | 31.08.2014 | 08   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]JPH0641135 (NIPPON SODA CO) [X] 1,5 * page 3, paragraph 0004 - page 6, paragraph 0007; compounds 1-7 *; | [X]WO2004092166 (MERCK & CO INC [US], et al) [X] 1-4,8,9 * page 142; example 159; claims 1-10, 18, 19 *; | [X]WO2005013894 (MERCK & CO INC [US], et al) [X] 1-4,8,9 * page 52; example 5; claims 1-10, 18 *; | [XP]WO2006088836 (SCHERING CORP [US], et al) [XP] 1,2,4,8,9 * page 44 - page 45; claims 1-44, 47, 48; compounds 22, 26, 27 *; | [X] - SHIRAI, K.; FUKUNISHI, K.; YANAGISAWA, A.; TAKAHASHI, H.; MATSUOKA, M., "New Syntheses and Spectral Properties of Pteridine-related Heterocycles from 2,5-Diamino-3,6-dicyanopyrazine", JOURNAL OF HETEROCYCLIC CHEMISTRY, (2000), vol. 37, ISSN 0022-152X, pages 1151 - 1156, XP002592558 [X] 1,2 * Scheme 1; page 1152; compound 3a * | [X] - ZHU ZHIJIAN ET AL, "Synthesis of Imidazo[4, 5-b]quinoxaline Ribonucleosides as Linear Dimensional Analogs of Antiviral Polyhalogenated Benzimidazole Ribonucleosides", JOURNAL OF THE CHINESE CHEMICAL SOCIETY, CHINESE ELECTRONIC PERIODICAL SERVICES, CHINA, (19980801), vol. 45, no. 4, ISSN 0009-4536, pages 465 - 474, XP009136216 [X] 1-5,8,9 * page 467, paragraph "Virological Procedure" "Cytotoxic Assays" - page 472; compounds 8a, 8b * | [A] - IUPAC ED - ALAN D MCNAUGHT AND ANDREW WILKINSON, "cycloalkyl groups", ISBN 978-0-86542-684-9, (19970101), COMPENDIUM OF CHEMICAL TERMINOLOGY : IUPAC RECOMMENDATIONS; [IUPAC CHEMICAL DATA SERIES], BLACKWELL SCIENCE, OXFORD [U.A.], URL: http://www.iupac.org/goldbook/C01498.pdf, (19970101), XP002585006 [A] 1-13 * the whole document * | [A] - IUPAC ED - ALAN D MCNAUGHT AND ANDREW WILKINSON, "alkyl groups", ISBN 978-0-86542-684-9, (19970101), COMPENDIUM OF CHEMICAL TERMINOLOGY : IUPAC RECOMMENDATIONS; [IUPAC CHEMICAL DATA SERIES], BLACKWELL SCIENCE, OXFORD [U.A.], URL: http://www.iupac.org/goldbook/A00228.pdf, (19970101), XP002585005 [A] 1-13 * the whole document * | [A] - VITSE O ET AL, "New Imidazo(1,2-a)pyrazine Derivatives with Brochodilatory and Cyclic Nucleotide Phosphodiesterase Inhibitory Activities", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB LNKD- DOI:10.1016/S0968-0896(99)00019-X, (19990101), vol. 7, ISSN 0968-0896, pages 1059 - 1065, XP002257093 [A] 1-13 * the whole document * DOI: http://dx.doi.org/10.1016/S0968-0896(99)00019-X | [A] - BONNET P A ET AL, "Synthesis and antibronchospastic activity of 8-alkoxy- and 8-(alkylamino)imidazo(1,2-a)pyrazines", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US LNKD- DOI:10.1021/JM00096A008, (19920101), vol. 35, no. 18, ISSN 0022-2623, pages 3353 - 3358, XP002971280 [A] 1-13 * the whole document * DOI: http://dx.doi.org/10.1021/jm00096a008 | by applicant | US3239345 | US4036979 | US4411890 | WO8907110 | WO8907111 | WO9304081 | US5488064 | US5491134 | US5541204 | WO9721993 | US5770615 | US5776983 | WO9900353 | US2002006962 | US6410254 | US2005197367 | - HUANG TG; HACKNEY D D, J BIOL CHEM, (1994), vol. 269, no. 23, pages 16493 - 501 | - CHEUNG ET AL., NATURE CELL BIOL., (2002), vol. 4, page 83 | - Remington's Pharmaceutical Sciences, MACK PUBLISHING COMPANY | - EDWARDS, J. P., BIO. MED. CHEM. LET., (1999), vol. 9, pages 1003 - 1008 | - HAMANN, L. G., J. MED. CHEM., (1999), vol. 42, pages 210 - 212 | - ZOT HG; POTTER J D., PREPARATIVE BIOCHEMISTRY, (1981), vol. 11, pages 381 - 395 | - SPUDICH J A; WATT S., J. BIOL. CHEM., (1971), vol. 246, pages 4866 - 4871 | - SMILLIE LB., METHODS ENZYMOL, (1981), pages 234 - 41 | - ZOT; POTTER, PREP. BIOCHEM., (1981), vol. 11, no. 4, pages 381 - 395 | - MARGOSSIAN, S.S.; LOWEY, S., METHODS ENZYMOL., (1982), vol. 85, pages 55 - 123 | - GOLDMANN, W.H.; GEEVES, M.A., ANAL. BIOCHEM., (1991), vol. 192, pages 55 - 58 | US20040987165 | US20000519079 |