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Extract from the Register of European Patents

EP About this file: EP2813504

EP2813504 - 4-Amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one derivatives, synthesis and uses thereof [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.11.2015
Database last updated on 14.11.2024
Most recent event   Tooltip27.11.2015Application deemed to be withdrawnpublished on 30.12.2015  [2015/53]
Applicant(s)For all designated states
Institut Quimic De Sarriá Cets, Fundació Privada
Vía Augusta 390
08017 Barcelona / ES
For all designated states
Hospital Clínic de Barcelona
C/ Villaroel, 170
08036 Barcelona / ES
For all designated states
Fundacio Clinic Per A La Recerca Biomedica
C / Rossello 149-153
08036 Barcelona / ES
For all designated states
Institut d'Investigacions Biomédiques August Pi i Sunyer
C/ Rosselló, 149-153
08036 Barcelona / ES
[2014/51]
Inventor(s)01 / Borrell Bilbao, José Ignacio
INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ PRIVADA
Via Augusta, 390
E-08017 Barcelona / ES
02 / Teixido Closa, Jordi
INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ PRIVADA
Via Augusta, 390
E-08017 Barcelona / ES
03 / Puig De La Bellacasa Cazorla, Raimon
INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ PRIVADA
Via Augusta, 390
E-08017 Barcelona / ES
04 / Colomer Pujol, Dolors
HOSPITAL CLÍNIC DE BARCELONA
Villarroel, 170
E-08036 Barcelona / ES
05 / Roue, Gael
FUNDACIÓ CLINIC PER A LA RECERCA BIOMÈDICA (FCRB)
Rosselló, 149-153
E-08036 Barcelona / ES
06 / Pérez Galán, Patricia
INSTITUT D ́INVESTIGACIONS BIOMÈDIQUES AUGUST PI I
SUNYER
Rosselló, 149-153
E-08036 Barcelona / ES
 [2014/51]
Representative(s)ABG Intellectual Property Law, S.L.
Avenida de Burgos, 16D
Edificio Euromor
28036 Madrid / ES
[N/P]
Former [2014/51]ABG Patentes, S.L.
Avenida de Burgos, 16D
Edificio Euromor
28036 Madrid / ES
Application number, filing date13382225.414.06.2013
[2014/51]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2813504
Date:17.12.2014
Language:EN
[2014/51]
Search report(s)(Supplementary) European search report - dispatched on:EP11.10.2013
ClassificationIPC:C07D471/04, A61K31/519, A61P35/00
[2014/51]
CPC:
C07D471/04 (EP,US); A61K31/136 (US); A61K31/395 (EP,US);
A61K31/435 (US); A61K31/4353 (US); A61K31/4375 (US);
A61K31/495 (US); A61K31/496 (US); A61P35/00 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/51]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:4-Amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-on-Derivate, Synthese und Verwendungen davon[2014/51]
English:4-Amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one derivatives, synthesis and uses thereof[2014/51]
French:4-Amino-6-(2,6-dichlorophényl)-2-(phénylamino)-pyrido [2,3-d]pyrimidin-7(8h)-one, leur synthèse et leurs utilisations[2014/51]
Examination procedure14.06.2013Examination requested  [2014/51]
18.06.2015Application deemed to be withdrawn, date of legal effect  [2015/53]
27.07.2015Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2015/53]
Fees paidPenalty fee
Additional fee for renewal fee
30.06.201503   M06   Not yet paid
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Documents cited:Search[A]WO2004063195  (SLOAN KETTERING INST CANCER [US], et al) [A] 1-15 * Claims; page 3, lines 8-11; page 48, lines 22-30; page 63, line 27 to page 64, line 19; page 78, table 1; page 84, lines 20-31. *;
 [A]US2009312321  (REN PINGDA [US], et al) [A] 1-15 * Abstract; claims; examples; pages 12-15, section "pharmacology and utility", particularly paragraphs 0107, 0109, 0130-0131, 0135. *;
 [A]US2009062274  (BAIK TAE-GON [US], et al) [A] 1-15 * Paragraphs 0011-0021; pages 15-29, table 1: examples; paragraph 0109: non-Hodgkin's lymphoma. *;
 [A]WO2012028756  (INST QUIMIC DE SARRIA CETS FUNDACIO PRIVADA [ES], et al) [A] 1-15 * Abstract; page 1, line 23 to page 2, line 2; page 3, lines 12-16; claims; page 19, lines 12-33: example of formula 3. *;
 [A]US2013116262  (CRAWFORD JAMES JOHN [US], et al) [A] 1-15 * Abstract; claims 1, 18, 22; examples. *;
 [A]  - KLUTCHKO ET AL., "2-SUBSTITUTED AMINOPYRIDO(2,3-D)PYRIMIDIN-7(8H)-ONES. STRUCTURE-ACTIVITY RELATIONSHIPS AGAINST SELECTED TYROSINE KINASES AND IN VITRO AND IN VIVO ANTICANCER ACTIVITY", J. MED. CHEM., (19980101), vol. 41, no. 17, doi:10.1021/JM9802259, ISSN 0022-2623, pages 3276 - 3292, XP002191992 [A] 1-15 * Title; abstract; tables 1-3. *

DOI:   http://dx.doi.org/10.1021/jm9802259
 [A]  - ANTCZAK ET AL., "Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: Toward selective Abl inhibitors", BIOORG. MED. CHEM. LETT., vol. 19, no. 24, doi:10.1016/J.BMCL.2009.10.085, ISSN 0960-894X, (20091215), pages 6872 - 6876, (20091023), XP026754138 [A] 1-15 * Title; abstract; tables 1-4. *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2009.10.085
 [A]  - YAN ET AL., "Bruton's Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies", J. MED. CHEM., (20120306), vol. 55, no. 10, doi:10.1021/jm300035p, ISSN 0022-2623, pages 4539 - 4550, XP055080230 [A] 1-15 * The whole document. In particular "introduction" and page 4540, table 1: compounds 6, 7. *

DOI:   http://dx.doi.org/10.1021/jm300035p
by applicantUS3702889
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.