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EP About this file: EP2812315

EP2812315 - PYRROLIC DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES AS A DRUG [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 09.12.2016 Database last updated on 18.03.2026
Most recent event Tooltip	12.10.2018	Lapse of the patent in a contracting state New state(s): AL	published on 14.11.2018 [2018/46]
Applicant(s)	For all designated states Université Grenoble Alpes 621, Avenue Centrale 38401 Saint-Martin-d'Hères / FR
	For all designated states Centre Hospitalier Universitaire de Grenoble BP 217 38043 Grenoble Cedex 9 / FR
	For all designated states Centre National de la Recherche Scientifique 3, rue Michel Ange 75794 Paris Cedex 16 / FR
	[N/P]
Former [2016/27]	For all designated states Université Grenoble Alpes 621, avenue Centrale 38401 Saint Martin d'Heres / FR
	For all designated states Centre Hospitalier Universitaire de Grenoble BP 217 38043 Grenoble Cedex 9 / FR
	For all designated states Centre National de la Recherche Scientifique 3, rue Michel-Ange 75794 Paris Cedex 16 / FR
Former [2014/51]	For all designated states Universite Joseph Fourier 621 avenue Centrale Domaine universitaire BP 53 34000 Saint-Martin d'Heres / FR
	For all designated states Centre Hospitalier Universitaire de Grenoble BP 217 38043 Grenoble Cedex 9 / FR
	For all designated states Centre National de la Recherche Scientifique 3, rue Michel-Ange 75794 Paris Cedex 16 / FR
Inventor(s)	01 / PELLOUX-LEON, Nadia 135 chemin des Vergers F-38190 Bernin / FR
	02 / MINASSIAN, Frédéric 384 route de Veurey F-38340 Voreppe / FR
	03 / MAURIN, Max, Maurin, Louis 11 allée du Bouilleur de Cru F-38240 Meylan / FR
	04 / DENIS, Jean-Noël 1102 Route du Général de Gaulle Apt 01 Bât. A7 Les Simianes F-38560 Jarrie / FR
	[2014/51]
Representative(s)	Grosset-Fournier, Chantal Catherine, et al Grosset-Fournier & Demachy 54, rue Saint-Lazare 75009 Paris / FR
	[2014/51]
Application number, filing date	13703410.4	08.02.2013
	[2016/05]
	WO2013EP52622
Priority number, date	EP20120305149	10.02.2012 Original published format: EP 12305149
	[2014/51]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2013117749
	Date:	15.08.2013
	Language:	EN
	[2013/33]
	Type:	A1 Application with search report
	No.:	EP2812315
	Date:	17.12.2014
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 15.08.2013 takes the place of the publication of the European patent application.
	[2014/51]
	Type:	B1 Patent specification
	No.:	EP2812315
	Date:	03.02.2016
	Language:	EN
	[2016/05]
Search report(s)	International search report - published on:	EP	15.08.2013
Classification	IPC:	C07D207/333, C07D405/06, C07D409/06, A61K31/40, A61K31/4025, A61P31/04	[2014/51]
	CPC:	C07D405/06 (EP); A61P31/04 (EP); C07D207/333 (EP); C07D409/06 (EP)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/51]
Extension states	BA	Not yet paid
	ME	Not yet paid
Title	German:	PYRROLDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN VERWENDUNGEN ALS ANTIBIOTIKA	[2015/32]
	English:	PYRROLIC DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES AS A DRUG	[2014/51]
	French:	DÉRIVÉS DE PYRROLE, LEURS PROCÉDÉS DE PRÉPARATION ET LEURS UTILISATIONS EN TANT QU'ANTIBIOTIQUES	[2015/32]
	Former [2014/51]	PYRROLDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNGEN ALS ARZNEIMITTEL
	Former [2014/51]	DÉRIVÉS PYRROLIQUES, PROCÉDÉS DE PRÉPARATION DE CEUX-CI ET LEUR UTILISATION COMME MÉDICAMENTS
Entry into regional phase	08.08.2014	National basic fee paid
	08.08.2014	Designation fee(s) paid
	08.08.2014	Examination fee paid
Examination procedure	08.08.2014	Examination requested [2014/51]
	19.03.2015	Amendment by applicant (claims and/or description)
	20.07.2015	Communication of intention to grant the patent
	19.11.2015	Fee for grant paid
	19.11.2015	Fee for publishing/printing paid
	19.11.2015	Receipt of the translation of the claim(s)
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 20.07.2015
Opposition(s)	04.11.2016	No opposition filed within time limit [2017/02]
Fees paid	Renewal fee
	28.02.2015	Renewal fee patent year 03
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	08.02.2013
	AL	03.02.2016
	AT	03.02.2016
	BE	03.02.2016
	CY	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	MC	03.02.2016
	MK	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SI	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	TR	03.02.2016
	LU	08.02.2016
	MT	29.02.2016
	BG	03.05.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
	[2018/46]
Former [2018/45]	HU	08.02.2013
	AT	03.02.2016
	BE	03.02.2016
	CY	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	MC	03.02.2016
	MK	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SI	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	TR	03.02.2016
	LU	08.02.2016
	MT	29.02.2016
	BG	03.05.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2018/31]	HU	08.02.2013
	AT	03.02.2016
	BE	03.02.2016
	CY	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	MC	03.02.2016
	MK	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SI	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	LU	08.02.2016
	MT	29.02.2016
	BG	03.05.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2018/30]	HU	08.02.2013
	AT	03.02.2016
	BE	03.02.2016
	CY	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	MC	03.02.2016
	MK	03.02.2016
	MT	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SI	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	LU	08.02.2016
	BG	03.05.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2017/47]	AT	03.02.2016
	BE	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	MT	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SI	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	BG	03.05.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2017/16]	AT	03.02.2016
	BE	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SI	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	BG	03.05.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2017/03]	AT	03.02.2016
	BE	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2016/50]	AT	03.02.2016
	CZ	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RO	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	SK	03.02.2016
	SM	03.02.2016
	BE	29.02.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2016/49]	AT	03.02.2016
	DK	03.02.2016
	EE	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	BE	29.02.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2016/46]	AT	03.02.2016
	DK	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	BE	29.02.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2016/39]	AT	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	LV	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	RS	03.02.2016
	SE	03.02.2016
	BE	29.02.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2016/38]	AT	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	BE	29.02.2016
	NO	03.05.2016
	GR	04.05.2016
	IS	03.06.2016
	PT	03.06.2016
Former [2016/36]	AT	03.02.2016
	FI	03.02.2016
	HR	03.02.2016
	LT	03.02.2016
	NL	03.02.2016
	PL	03.02.2016
	BE	29.02.2016
	NO	03.05.2016
	GR	04.05.2016
Former [2016/35]	FI	03.02.2016
	HR	03.02.2016
	NO	03.05.2016
	GR	04.05.2016
Cited in	International search	[A] MUKULESH BARUAH ET AL: "BODIPY-Based Hydroxyaryl Derivatives as Fluorescent pH Probes", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 70, no. 10, 1 May 2005 (2005-05-01), pages 4152 - 4157, XP055024837, ISSN: 0022-3263, DOI: 10.1021/jo0503714 DOI: http://dx.doi.org/10.1021/jo0503714
		[A] LINGLING LI ET AL: "Syntheses and Spectral Properties of Functionalized, Water-Soluble BODIPY Derivatives", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 73, no. 5, 1 March 2008 (2008-03-01), pages 1963 - 1970, XP055024838, ISSN: 0022-3263, DOI: 10.1021/jo702463f DOI: http://dx.doi.org/10.1021/jo702463f
		[A] TAMANNA K. KHAN ET AL: "Synthesis and Photophysical Properties of 3,5-Bis(oxopyridinyl)- and 3,5-Bis(pyridinyloxy)-Substituted Boron-Dipyrromethenes", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2010, no. 12, 15 March 2010 (2010-03-15), pages 2314 - 2323, XP055024841, ISSN: 1434-193X, DOI: 10.1002/ejoc.200901460 DOI: http://dx.doi.org/10.1002/ejoc.200901460
		[A] VELLANKI LAKSHMI ET AL: "Synthesis of Sterically Crowded Polyarylated Boron-Dipyrromethenes", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 76, no. 20, 21 October 2011 (2011-10-21), pages 8466 - 8471, XP055024842, ISSN: 0022-3263, DOI: 10.1021/jo2010022 DOI: http://dx.doi.org/10.1021/jo2010022
		[AD] FAUGERAS P A ET AL: "Synthesis of meso-substituted dipyrromethanes using iodine-catalysis", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 51, no. 35, 1 September 2010 (2010-09-01), pages 4630 - 4632, XP027181454, ISSN: 0040-4039, [retrieved on 20100701]
		[A] J-P STRACHAN ET AL: "Rational Synthesis of Meso-Substituted Chlorin Building Blocks", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON.; US, vol. 65, 1 January 2000 (2000-01-01), pages 3160 - 3172, XP002547623, ISSN: 0022-3263, [retrieved on 20000427], DOI: 10.1021/JO991942T DOI: http://dx.doi.org/10.1021/JO991942T
		[A] TAMANNA K KHAN ET AL: "Synthesis of covalently linked borondipyrromethenechromophore conjugates using 3-bromo borondipyrromethene as a key precursor", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 67, no. 32, 20 May 2011 (2011-05-20), pages 5816 - 5824, XP028098690, ISSN: 0040-4020, [retrieved on 20110531], DOI: 10.1016/J.TET.2011.05.089 DOI: http://dx.doi.org/10.1016/j.tet.2011.05.089
		[A] TEMELLI B ET AL: "The reaction of N-tosyl imines with heteroaromatic compounds: a new access to triheteroarylmethanes", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 66, no. 34, 21 August 2010 (2010-08-21), pages 6765 - 6768, XP027173836, ISSN: 0040-4020, [retrieved on 20100703]
		[A] TEMELLI B ET AL: "A novel method for the synthesis of dipyrromethanes by metal triflate catalysis", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 62, no. 43, 23 October 2006 (2006-10-23), pages 10130 - 10135, XP025002912, ISSN: 0040-4020, [retrieved on 20061023], DOI: 10.1016/J.TET.2006.08.047 DOI: http://dx.doi.org/10.1016/j.tet.2006.08.047
		[A] DUDIC@? ET AL: "Synthesis of novel porphyrin-based biscalix[4]arenes", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 40, no. 32, 6 August 1999 (1999-08-06), pages 5949 - 5952, XP005050833, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(99)01181-8 [A] 14 * Schemes 1-2,;; compounds 10,11 * DOI: http://dx.doi.org/10.1016/S0040-4039(99)01181-8
		[A] CHRISTIAN BRCKNER ET AL: "Synthesis, derivatization and structural characterization of octahedral tris(5-phenyl-4,6-dipyrrinato) complexes of cobalt(III) and iron(III)", INORGANICA CHIMICA ACTA, vol. 263, no. 1-2, 1 October 1997 (1997-10-01), pages 279 - 286, XP055024928, ISSN: 0020-1693, DOI: 10.1016/S0020-1693(97)05700-9 [A] 14 * Scheme 1; page 1965; compounds F, 7b * DOI: http://dx.doi.org/10.1016/S0020-1693(97)05700-9
		[A] POLISETTI DHARMA RAO ET AL: "Rational Syntheses of Porphyrins Bearing up to Four Different Meso Substituents", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 65, no. 22, 1 November 2000 (2000-11-01), pages 7323 - 7344, XP055024931, ISSN: 0022-3263, DOI: 10.1021/jo000882k [A] 14 * page 2315; compounds 7-8 * DOI: http://dx.doi.org/10.1021/jo000882k
		[A] MARCIN PTASZEK ET AL: "Synthesis of 1-Formyldipyrromethanes", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 71, no. 11, 1 May 2006 (2006-05-01), pages 4328 - 4331, XP055024932, ISSN: 0022-3263, DOI: 10.1021/jo060119b [A] 14 * Scheme 2;; compounds 6-7 * DOI: http://dx.doi.org/10.1021/jo060119b
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