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Extract from the Register of European Patents

EP About this file: EP2825650

EP2825650 - RECOMBINATION SYSTEM [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.12.2019
Database last updated on 26.04.2025
FormerThe patent has been granted
Status updated on  11.01.2019
FormerGrant of patent is intended
Status updated on  29.08.2018
FormerExamination is in progress
Status updated on  18.01.2017
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
DSM IP Assets B.V.
Het Overloon 1
6411 TE Heerlen / NL
[N/P]
Former [2015/04]For all designated states
DSM IP Assets B.V.
Het Overloon 1
6411 TE Heerlen / NL
Inventor(s)01 / WIESSENHAAN, Nathalie
P.O.Box 130
NL-6100 AC Echt / NL
02 / KOLEN, Catharina Petronella Antonia Maria
P.O.Box 130
NL-6100 AC Echt / NL
03 / MEIJRINK, Bernard
P.O. Box 130
NL-6100 AC Echt / NL
04 / BOER, Viktor
P.O. Box 130
NL-6100 AC Echt / NL
05 / ROUBOS, Johannes, Andries
P.O. Box 130
NL-6100 AC Echt / NL
06 / ARENDSEN, Yvonne Johannes Odilia
P.O. Box 130
NL-6100 AC Echt / NL
 [2015/04]
Representative(s)dsm-firmenich IP
P.O. Box 4
6100 AA Echt / NL
[N/P]
Former [2019/07]DSM Intellectual Property
P.O. Box 4
6100 AA Echt / NL
Former [2015/04]Chadwick, Mark Craig, et al
DSM Intellectual Property
P.O. Box 4
6100 AA Echt / NL
Application number, filing date13708506.412.03.2013
[2019/07]
WO2013EP55047
Priority number, dateEP2012015909412.03.2012         Original published format: EP 12159094
[2015/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013135728
Date:19.09.2013
Language:EN
[2013/38]
Type: A1 Application with search report 
No.:EP2825650
Date:21.01.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 19.09.2013 takes the place of the publication of the European patent application.
[2015/04]
Type: B1 Patent specification 
No.:EP2825650
Date:13.02.2019
Language:EN
[2019/07]
Search report(s)International search report - published on:EP19.09.2013
ClassificationIPC:C12N15/63, C12N15/90, C12N15/00, C12N5/00
[2015/04]
CPC:
C12N15/102 (EP,US); C12N15/902 (EP); C12N2800/30 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/04]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:REKOMBINATIONSSYSTEM[2015/04]
English:RECOMBINATION SYSTEM[2015/04]
French:SYSTÈME DE RECOMBINAISON[2015/04]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase09.10.2014National basic fee paid 
09.10.2014Designation fee(s) paid 
09.10.2014Examination fee paid 
Examination procedure09.10.2014Examination requested  [2015/04]
26.05.2015Amendment by applicant (claims and/or description)
23.10.2015Despatch of a communication from the examining division (Time limit: M06)
02.05.2016Reply to a communication from the examining division
23.09.2016Despatch of a communication from the examining division (Time limit: M06)
03.05.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
06.07.2017Reply to a communication from the examining division
06.12.2017Despatch of a communication from the examining division (Time limit: M04)
16.04.2018Reply to a communication from the examining division
30.08.2018Communication of intention to grant the patent
20.12.2018Fee for grant paid
20.12.2018Fee for publishing/printing paid
20.12.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.10.2015
Opposition(s)14.11.2019No opposition filed within time limit [2020/04]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
06.07.2017Request for further processing filed
06.07.2017Full payment received (date of receipt of payment)
Request granted
21.07.2017Decision despatched
Fees paidRenewal fee
10.03.2015Renewal fee patent year 03
10.03.2016Renewal fee patent year 04
10.03.2017Renewal fee patent year 05
13.03.2018Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU12.03.2013
AL13.02.2019
AT13.02.2019
CY13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
MK13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SI13.02.2019
SK13.02.2019
SM13.02.2019
TR13.02.2019
IE12.03.2019
LU12.03.2019
MT12.03.2019
BE31.03.2019
CH31.03.2019
LI31.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
[2022/31]
Former [2021/33]HU12.03.2013
AL13.02.2019
AT13.02.2019
CY13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SI13.02.2019
SK13.02.2019
SM13.02.2019
TR13.02.2019
IE12.03.2019
LU12.03.2019
MT12.03.2019
BE31.03.2019
CH31.03.2019
LI31.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2021/26]AL13.02.2019
AT13.02.2019
CY13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SI13.02.2019
SK13.02.2019
SM13.02.2019
TR13.02.2019
IE12.03.2019
LU12.03.2019
MT12.03.2019
BE31.03.2019
CH31.03.2019
LI31.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2020/29]AL13.02.2019
AT13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SI13.02.2019
SK13.02.2019
SM13.02.2019
TR13.02.2019
IE12.03.2019
LU12.03.2019
MT12.03.2019
BE31.03.2019
CH31.03.2019
LI31.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2020/17]AL13.02.2019
AT13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SI13.02.2019
SK13.02.2019
SM13.02.2019
TR13.02.2019
IE12.03.2019
LU12.03.2019
BE31.03.2019
CH31.03.2019
LI31.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2020/11]AL13.02.2019
AT13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SI13.02.2019
SK13.02.2019
SM13.02.2019
IE12.03.2019
LU12.03.2019
BE31.03.2019
CH31.03.2019
LI31.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2020/09]AL13.02.2019
AT13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SK13.02.2019
SM13.02.2019
IE12.03.2019
LU12.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2020/03]AL13.02.2019
AT13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SK13.02.2019
SM13.02.2019
LU12.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2020/01]AL13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
MC13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SK13.02.2019
SM13.02.2019
LU12.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2019/52]AL13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
PL13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SK13.02.2019
SM13.02.2019
LU12.03.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2019/49]AL13.02.2019
CZ13.02.2019
EE13.02.2019
ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
RO13.02.2019
RS13.02.2019
SE13.02.2019
SK13.02.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2019/47]ES13.02.2019
HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
RS13.02.2019
SE13.02.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2019/46]HR13.02.2019
IT13.02.2019
LT13.02.2019
LV13.02.2019
RS13.02.2019
SE13.02.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2019/39]HR13.02.2019
LT13.02.2019
LV13.02.2019
RS13.02.2019
SE13.02.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
IS13.06.2019
PT13.06.2019
Former [2019/38]LT13.02.2019
SE13.02.2019
BG13.05.2019
NO13.05.2019
GR14.05.2019
PT13.06.2019
Former [2019/37]LT13.02.2019
SE13.02.2019
NO13.05.2019
GR14.05.2019
PT13.06.2019
Former [2019/34]LT13.02.2019
SE13.02.2019
NO13.05.2019
PT13.06.2019
Former [2019/33]LT13.02.2019
NO13.05.2019
PT13.06.2019
Cited inInternational search[A]  - ANDREAS F. KOLB, "Selection-Marker-Free Modification of the Murine [beta]-Casein Gene Using a lox2722 Site", ANALYTICAL BIOCHEMISTRY, (20010301), vol. 290, no. 2, doi:10.1006/abio.2000.4984, ISSN 0003-2697, pages 260 - 271, XP055033798 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1006/abio.2000.4984
 [A]  - CHEREPANOV P P ET AL, "Gene disruption in Escherichia coli: Tc and Km cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant", GENE, ELSEVIER, AMSTERDAM, NL, (19950101), vol. 158, no. 1, doi:10.1016/0378-1119(95)00193-A, ISSN 0378-1119, pages 9 - 14, XP004206666 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1016/0378-1119(95)00193-A
 [A]  - BANG-JAU YOU ET AL, "Gene-specific disruption in the filamentous fungus Cercospora nicotianae using a split-marker approach", ARCHIVES OF MICROBIOLOGY, SPRINGER, BERLIN, DE, (20090609), vol. 191, no. 7, ISSN 1432-072X, pages 615 - 622, XP019701743 [A] 1-17 * the whole document *
 [A]  - MUNEHIRO UEMURA ET AL, "Chromosomal Manipulation by Site-Specific Recombinases and Fluorescent Protein-Based Vectors", PLOS ONE, (20100324), vol. 5, no. 3, doi:10.1371/journal.pone.0009846, page E9846, XP055033795 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1371/journal.pone.0009846
 [A]  - METZGER D ET AL, "CONDITIONAL SITE-SPECIFIC RECOMBINATION IN MAMMALIAN CELLS USING A LIGAND-DEPENDENT CHIMERIC CRE RECOMBINASE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, (19950718), vol. 92, no. 15, doi:10.1073/PNAS.92.15.6991, ISSN 0027-8424, pages 6991 - 6995, XP000615550 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.92.15.6991
 [A]  - FU J ET AL, "Split marker transformation increases homologous integration frequency in Cryptococcus neoformans", FUNGAL GENETICS AND BIOLOGY, SAN DIEGO, CA, US, vol. 43, no. 3, doi:10.1016/J.FGB.2005.09.007, ISSN 1087-1845, (20060301), pages 200 - 212, (20060301), XP024918894 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.fgb.2005.09.007
 [A]  - BODE JUERGEN ET AL, "The transgeneticist's toolbox: Novel methods for the targeted modification of eukaryotic genomes", BIOLOGICAL CHEMISTRY, WALTER DE GRUYTER GMBH & CO, BERLIN, DE, (20000901), vol. 381, no. 9-10, doi:10.1515/BC.2000.103, ISSN 1431-6730, pages 801 - 813, XP002282829 [A] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1515/BC.2000.103
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.