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Extract from the Register of European Patents

EP About this file: EP2846819

EP2846819 - VARIANTS OF TACE PRO-DOMAIN AS TNF-A INHIBITOR AND THEIR MEDICAL USE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.03.2018
Database last updated on 25.09.2024
FormerThe patent has been granted
Status updated on  31.03.2017
FormerGrant of patent is intended
Status updated on  03.01.2017
FormerExamination is in progress
Status updated on  11.11.2016
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Yeda Research and Development Co. Ltd.
At the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
[2017/18]
Former [2015/12]For all designated states
Yeda Research and Development Co. Ltd.
At the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
Inventor(s)01 / SAGI, Irit
2 Meonot WIX
7610002 Rehovot / IL
02 / WONG, Eitan
c/o Yeda Research And Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
03 / AFIK, Ran
c/o Yeda Research And Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
 [2015/12]
Representative(s)Dennemeyer & Associates S.A.
Postfach 70 04 25
81304 München / DE
[N/P]
Former [2017/18]Dennemeyer & Associates S.A.
55, rue des Bruyères
1274 Howald / LU
Former [2015/12]Vogel, Andreas, et al
Bals & Vogel Universitätsstrasse 142
44799 Bochum / DE
Application number, filing date13729107.609.05.2013
[2017/18]
WO2013IL50400
Priority number, dateUS201261644551P09.05.2012         Original published format: US 201261644551 P
[2015/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013168164
Date:14.11.2013
Language:EN
[2013/46]
Type: A1 Application with search report 
No.:EP2846819
Date:18.03.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 14.11.2013 takes the place of the publication of the European patent application.
[2015/12]
Type: B1 Patent specification 
No.:EP2846819
Date:03.05.2017
Language:EN
[2017/18]
Search report(s)International search report - published on:EP14.11.2013
ClassificationIPC:A61K38/17, C07K14/00
[2015/12]
CPC:
A61K38/4886 (EP,US); A61P1/04 (EP); A61P1/16 (EP);
A61P29/00 (EP); A61P35/00 (EP); A61P37/02 (EP);
A61P43/00 (EP); C12N9/6489 (EP,US); C12Y304/24086 (EP,US);
Y02A50/30 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/12]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VARIANTEN DER TACE PRO-DOMÄNE ALS TNF-A-HEMMER UND DEREN MEDIZINISCHE VERWENDUNG[2015/12]
English:VARIANTS OF TACE PRO-DOMAIN AS TNF-A INHIBITOR AND THEIR MEDICAL USE[2015/12]
French:VARIANTS DE PRO-DOMAINE TACE EN TANT QU'INHIBITEUR DE TNF-A ET LEUR UTILISATION MÉDICALE[2015/12]
Entry into regional phase09.12.2014National basic fee paid 
09.12.2014Designation fee(s) paid 
09.12.2014Examination fee paid 
Examination procedure25.11.2014Amendment by applicant (claims and/or description)
09.12.2014Examination requested  [2015/12]
01.07.2016Despatch of a communication from the examining division (Time limit: M04)
09.11.2016Reply to a communication from the examining division
04.01.2017Communication of intention to grant the patent
21.03.2017Fee for grant paid
21.03.2017Fee for publishing/printing paid
21.03.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  01.07.2016
Opposition(s)06.02.2018No opposition filed within time limit [2018/15]
Fees paidRenewal fee
12.05.2015Renewal fee patent year 03
10.05.2016Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU09.05.2013
AL03.05.2017
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
PT03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
TR03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
[2020/34]
Former [2020/28]HU09.05.2013
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
PT03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
TR03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2020/15]HU09.05.2013
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
TR03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/51]HU09.05.2013
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
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LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/48]HU09.05.2013
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/31]HU09.05.2013
AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
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LV03.05.2017
MC03.05.2017
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PL03.05.2017
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SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/30]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/43]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
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RS03.05.2017
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SI03.05.2017
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SM03.05.2017
IE09.05.2017
LU09.05.2017
MT09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
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IS03.09.2017
Former [2018/39]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
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NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE09.05.2017
LU09.05.2017
BE31.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/25]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
FI03.05.2017
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SM03.05.2017
IE09.05.2017
LU09.05.2017
BG03.08.2017
NO03.08.2017
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IS03.09.2017
Former [2018/17]AT03.05.2017
CZ03.05.2017
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EE03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
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PL03.05.2017
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SK03.05.2017
SM03.05.2017
LU09.05.2017
BG03.08.2017
NO03.08.2017
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Former [2018/11]AT03.05.2017
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FI03.05.2017
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NO03.08.2017
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BG03.08.2017
NO03.08.2017
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Former [2018/09]AT03.05.2017
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PL03.05.2017
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NO03.08.2017
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IS03.09.2017
Former [2017/52]AT03.05.2017
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HR03.05.2017
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LV03.05.2017
NL03.05.2017
PL03.05.2017
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SE03.05.2017
BG03.08.2017
NO03.08.2017
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IS03.09.2017
Former [2017/50]AT03.05.2017
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HR03.05.2017
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LV03.05.2017
PL03.05.2017
RS03.05.2017
SE03.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2017/49]AT03.05.2017
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HR03.05.2017
LT03.05.2017
NO03.08.2017
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IS03.09.2017
Cited inInternational search[A]WO2005030798  (US GOV HEALTH & HUMAN SERV [US], et al) [A] 1-42 * example 2 * * page 6, line 28 - page 7, line 5 * * page 1c; figure 1c *
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DOI:   http://dx.doi.org/10.1074/jbc.M401311200
 [A]  - LI XIAOOU ET AL, "The study of the inhibition of the recombinant TACE prodomain to endotoxemia in mice", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, BASEL, CH, (20091218), vol. 10, no. 12, doi:10.3390/IJMS10125442, ISSN 1422-0067, pages 5442 - 5454, XP009172684 [A] 1-42 * the whole document *

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