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Extract from the Register of European Patents

EP About this file: EP2850093

EP2850093 - THERAPEUTIC IL-13 POLYPEPTIDES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  15.11.2019
Database last updated on 27.07.2024
FormerThe patent has been granted
Status updated on  07.12.2018
FormerGrant of patent is intended
Status updated on  16.07.2018
FormerExamination is in progress
Status updated on  20.06.2018
FormerGrant of patent is intended
Status updated on  12.02.2018
FormerExamination is in progress
Status updated on  06.01.2017
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, Third Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
[2019/38]
Former [2019/02]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel Building 170
3rd Floor, Main Quad
P.O. Box 20386
Stanford CA 94305-2038 / US
Former [2015/25]For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel Building 170
3rd Floor, Main Quad
P.O. Box 20386
Stanford CA 94305-2038 / US
Former [2015/24]For all designated states
The Board of Trustees of the Leland Stanford Junior University
3th Floor, Main Quad
P.O. Box 20386
Stanford CA 94305-2038 / US
Former [2015/13]For all designated states
The Board of Trustees of the Leland Stanford Junior University
1705 El Camino Real
Palo Alto CA 94306-1106 / US
Inventor(s)01 / GARCIA, Kenan Christopher
580 Kenwood Drive
Menlo Park California 94025 / US
02 / GONZALEZ, Ignacio Moraga
2042 Yale Street
Palo Alto, CA 94306 / US
 [2015/13]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2019/02]Sutcliffe, Nicholas Robert, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Former [2015/13]Sutcliffe, Nicholas Robert, et al
Mewburn Ellis LLP
33 Gutter Lane
London EC2V 8AS / GB
Application number, filing date13740741.725.01.2013
[2019/02]
WO2013US23194
Priority number, dateUS201261591781P27.01.2012         Original published format: US 201261591781 P
[2015/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013112871
Date:01.08.2013
Language:EN
[2013/31]
Type: A1 Application with search report 
No.:EP2850093
Date:25.03.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 01.08.2013 takes the place of the publication of the European patent application.
[2015/13]
Type: B1 Patent specification 
No.:EP2850093
Date:09.01.2019
Language:EN
[2019/02]
Search report(s)International search report - published on:US01.08.2013
(Supplementary) European search report - dispatched on:EP29.01.2016
ClassificationIPC:C07K1/00, A61K38/00
[2015/13]
CPC:
C07K14/5437 (EP,US); C07K16/00 (US); G09G3/2003 (US);
G09G3/2074 (US); H04N19/176 (US); H04N19/182 (US);
A61K38/2086 (EP,US); C07K2319/00 (US); C07K2319/30 (US);
G09G2320/0247 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/13]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:THERAPEUTISCHE IL-13-POLYPEPTIDE[2015/13]
English:THERAPEUTIC IL-13 POLYPEPTIDES[2015/13]
French:POLYPEPTIDES D'IL-13 THÉRAPEUTIQUES[2015/13]
Entry into regional phase04.09.2014National basic fee paid 
04.09.2014Search fee paid 
04.09.2014Designation fee(s) paid 
04.09.2014Examination fee paid 
Examination procedure04.09.2014Examination requested  [2015/13]
05.08.2016Amendment by applicant (claims and/or description)
09.01.2017Despatch of a communication from the examining division (Time limit: M04)
20.03.2017Reply to a communication from the examining division
13.02.2018Communication of intention to grant the patent
14.06.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
17.07.2018Communication of intention to grant the patent
27.11.2018Fee for grant paid
27.11.2018Fee for publishing/printing paid
27.11.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.01.2017
Opposition(s)10.10.2019No opposition filed within time limit [2019/51]
Request for further processing for:11.09.2014Request for further processing filed
11.09.2014Full payment received (date of receipt of payment)
Request granted
24.09.2014Decision despatched
The application is deemed to be withdrawn due to non-payment of the search fee
04.09.2014Request for further processing filed
04.09.2014Full payment received (date of receipt of payment)
Request granted
24.09.2014Decision despatched
04.09.2014Request for further processing filed
04.09.2014Full payment received (date of receipt of payment)
Request granted
24.09.2014Decision despatched
The application is deemed to be withdrawn due to non-payment of the filing fee
04.09.2014Request for further processing filed
04.09.2014Full payment received (date of receipt of payment)
Request granted
24.09.2014Decision despatched
The application is deemed to be withdrawn due to non-payment of the examination fee
04.09.2014Request for further processing filed
04.09.2014Full payment received (date of receipt of payment)
Request granted
24.09.2014Decision despatched
The application is deemed to be withdrawn due to non-payment of designation fees
TR, SM, SK, SI, SE, RS, RO, PT, PL, NO, NL, MT, MK, MC, LV, LU, LT, IT, IS, IE, HU, HR, GR, GB, FR, FI, ES, EE, DK, DE, CZ, CY, CH, BG, BE, AT, AL
04.09.2014Request for further processing filed
04.09.2014Full payment received (date of receipt of payment)
Request granted
24.09.2014Decision despatched
Fees paidRenewal fee
26.01.2015Renewal fee patent year 03
11.01.2016Renewal fee patent year 04
11.01.2017Renewal fee patent year 05
11.06.2018Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.01.201806   M06   Fee paid on   11.06.2018
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.01.2013
AL09.01.2019
AT09.01.2019
CY09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
MK09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SI09.01.2019
SK09.01.2019
SM09.01.2019
TR09.01.2019
IE25.01.2019
LU25.01.2019
MT25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
[2022/31]
Former [2021/32]HU25.01.2013
AL09.01.2019
AT09.01.2019
CY09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SI09.01.2019
SK09.01.2019
SM09.01.2019
TR09.01.2019
IE25.01.2019
LU25.01.2019
MT25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2021/26]AL09.01.2019
AT09.01.2019
CY09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SI09.01.2019
SK09.01.2019
SM09.01.2019
TR09.01.2019
IE25.01.2019
LU25.01.2019
MT25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2020/29]AL09.01.2019
AT09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SI09.01.2019
SK09.01.2019
SM09.01.2019
TR09.01.2019
IE25.01.2019
LU25.01.2019
MT25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2020/17]AL09.01.2019
AT09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SI09.01.2019
SK09.01.2019
SM09.01.2019
TR09.01.2019
IE25.01.2019
LU25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2020/13]AL09.01.2019
AT09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SI09.01.2019
SK09.01.2019
SM09.01.2019
IE25.01.2019
LU25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2020/09]AL09.01.2019
AT09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SK09.01.2019
SM09.01.2019
IE25.01.2019
LU25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/51]AL09.01.2019
AT09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SK09.01.2019
SM09.01.2019
LU25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/50]AL09.01.2019
AT09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SK09.01.2019
LU25.01.2019
BE31.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/49]AL09.01.2019
AT09.01.2019
CZ09.01.2019
DK09.01.2019
EE09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RO09.01.2019
RS09.01.2019
SE09.01.2019
SK09.01.2019
LU25.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/48]AT09.01.2019
DK09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RS09.01.2019
SE09.01.2019
LU25.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/46]AT09.01.2019
ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
MC09.01.2019
NL09.01.2019
PL09.01.2019
RS09.01.2019
SE09.01.2019
LU25.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/44]ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
NL09.01.2019
PL09.01.2019
RS09.01.2019
SE09.01.2019
LU25.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/39]ES09.01.2019
FI09.01.2019
HR09.01.2019
LT09.01.2019
LV09.01.2019
NL09.01.2019
PL09.01.2019
RS09.01.2019
SE09.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
IS09.05.2019
PT09.05.2019
Former [2019/38]ES09.01.2019
FI09.01.2019
LT09.01.2019
NL09.01.2019
PL09.01.2019
SE09.01.2019
BG09.04.2019
NO09.04.2019
GR10.04.2019
PT09.05.2019
Former [2019/37]ES09.01.2019
FI09.01.2019
LT09.01.2019
NL09.01.2019
PL09.01.2019
SE09.01.2019
NO09.04.2019
GR10.04.2019
PT09.05.2019
Former [2019/35]ES09.01.2019
FI09.01.2019
LT09.01.2019
NL09.01.2019
PL09.01.2019
SE09.01.2019
NO09.04.2019
PT09.05.2019
Former [2019/34]FI09.01.2019
LT09.01.2019
NL09.01.2019
SE09.01.2019
NO09.04.2019
PT09.05.2019
Former [2019/33]FI09.01.2019
LT09.01.2019
NL09.01.2019
NO09.04.2019
PT09.05.2019
Former [2019/30]NL09.01.2019
Documents cited:Search[A]WO0125282  (PENN STATE RES FOUND [US], et al) [A] 1-15 * page 3 - page 4; example 3 *;
 [A]WO0218422  (PENN STATE RES FOUND [US]) [A] 1-15 * abstract * * page 1, paragraph l - page 3, paragraph 1 * * page 9, paragraph 2 * * page 11, paragraph 2 *;
 [A]  - MADHANKUMAR A B ET AL, "INTERLEUKIN 13 MUTANTS OF ENHANCED AVIDITY TOWARD THE GLIOMA-ASSOCIATED RECEPTOR, IL13RALPHA2", NEOPLASIA, DOYMA, BARCELONA, ES, (20040101), vol. 6, no. 1, ISSN 0212-9787, pages 15 - 22, XP009031947 [A] 1-15 * abstract *
 [A]  - EISENMESSER E Z ET AL, "Solution structure of interleukin-13 and insights into receptor engagement", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (20010629), vol. 310, no. 1, doi:10.1006/JMBI.2001.4765, ISSN 0022-2836, pages 231 - 241, XP004464194 [A] 1-15 * abstract * * page 237 - page 238; figures 5,6 *

DOI:   http://dx.doi.org/10.1006/jmbi.2001.4765
 [A]  - THOMPSON J P ET AL, "MUTANTS OF INTERLEUKIN 13 WITH ALTERED REACTIVITY TOWARD INTERLEUKIN 13 RECEPTORS", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (19991015), vol. 274, no. 42, doi:10.1074/JBC.274.42.29944, ISSN 0021-9258, pages 29944 - 29950, XP002948379 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.274.42.29944
International search[A]US2003013851  (POWERS ROBERT [US], et al);
 [A]US2007160658  (CONNOR JAMES R [US], et al);
 [X]  - MADHANKUMAR ET AL., "Interleukin 13 Mutants of Enhanced Avidity Toward the Glioma- Associated Receptor", IL13RA2. NEOPLASIA., (2004), vol. 6, no. 1, pages 15 - 22, XP009031947
 [Y]  - PARTALEDIS ET AL., "In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 (HIV-1) Isolates with Reduced Sensitivity to Hydroxyethylamino Sulfonamide Inhibitors of HIV-1 Aspartyl Protease.", J VIROL., (1995), vol. 69, no. 9, pages 5228 - 5235, XP000652673
 [A]  - EISENMESSER ET AL., "Solution structure of interleukin-13 and insights into receptor engagement.", J MOL BIOL., (2001), vol. 310, no. 1, pages 231 - 241, XP004464194

DOI:   http://dx.doi.org/10.1006/jmbi.2001.4765
 [A]  - ITO ET AL., "Distinct Structural Requirements for Interleukin-4 (IL-4) and IL-13 Binding to the Shared IL-13 Receptor Facilitate Cellular Tuning of Cytokine Responsiveness.", J BIOL CHEM. 2009, vol. 284, no. 36, pages 24289 - 24296, XP055161091

DOI:   http://dx.doi.org/10.1074/jbc.M109.007286
 [A]  - THOMPSON ET AL., "Mutants of interleukin 13 with altered reactivity toward interleukin 13 receptors.", J. BIOL. CHEM., (1999), vol. 274, no. 42, pages 29944 - 29950, XP002948379

DOI:   http://dx.doi.org/10.1074/jbc.274.42.29944
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.