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Extract from the Register of European Patents

EP About this file: EP2814464

EP2814464 - THERMOSENSITIVE NANOPARTICLE FORMULATIONS AND METHOD OF MAKING THE SAME [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.10.2020
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  15.11.2019
FormerGrant of patent is intended
Status updated on  18.07.2019
FormerExamination is in progress
Status updated on  17.08.2018
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK
published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Celsion Corporation
997 Lenox Drive
Suite 100
Lawrenceville, NJ 08648 / US
[2014/52]
Inventor(s)01 / REED, Robert, A.
1327 Hilltown Pike
Line Lexington, PA 18932 / US
02 / SU, Daishui
8754 F Town Country Boulevard
Ellicott City, MD 21043 / US
 [2014/52]
Representative(s)Ledl, Andreas
Maiwald GmbH
Elisenhof
Elisenstraße 3
80335 München / DE
[N/P]
Former [2019/51]Ledl, Andreas
Maiwald Patentanwalts- und
Rechtsanwaltsgesellschaft mbH
Elisenhof
Elisenstraße 3
80335 München / DE
Former [2014/52]Ledl, Andreas
Maiwald Patentanwalts GmbH Elisenhof Elisenstraße 3
80335 München / DE
Application number, filing date13748684.115.02.2013
[2019/51]
WO2013US26453
Priority number, dateUS201261600418P17.02.2012         Original published format: US 201261600418 P
[2014/52]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013123407
Date:22.08.2013
Language:EN
[2013/34]
Type: A1 Application with search report 
No.:EP2814464
Date:24.12.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 22.08.2013 takes the place of the publication of the European patent application.
[2014/52]
Type: B1 Patent specification 
No.:EP2814464
Date:18.12.2019
Language:EN
[2019/51]
Search report(s)International search report - published on:US22.08.2013
(Supplementary) European search report - dispatched on:EP07.07.2015
ClassificationIPC:A61K9/127
[2014/52]
CPC:
A61K31/704 (EP,US); A61K9/127 (US); A61K9/1271 (EP,US);
A61K9/1278 (EP,US); A61P35/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/52]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:WÄRMEEMPFINDLICHE NANOPARTIKELFORMULIERUNGEN UND HERSTELLUNGSVERFAHREN DAFÜR[2014/52]
English:THERMOSENSITIVE NANOPARTICLE FORMULATIONS AND METHOD OF MAKING THE SAME[2014/52]
French:FORMULATIONS DE NANOPARTICULES THERMOSENSIBLES ET LEUR PROCÉDÉ DE FABRICATION[2014/52]
Entry into regional phase04.09.2014National basic fee paid 
04.09.2014Search fee paid 
04.09.2014Designation fee(s) paid 
04.09.2014Examination fee paid 
Examination procedure04.09.2014Examination requested  [2014/52]
11.03.2016Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
10.05.2016Amendment by applicant (claims and/or description)
22.08.2018Despatch of a communication from the examining division (Time limit: M06)
26.02.2019Reply to a communication from the examining division
19.07.2019Communication of intention to grant the patent
11.11.2019Fee for grant paid
11.11.2019Fee for publishing/printing paid
11.11.2019Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.08.2018
Opposition(s)21.09.2020No opposition filed within time limit [2020/48]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
10.05.2016Request for further processing filed
10.05.2016Full payment received (date of receipt of payment)
Request granted
24.05.2016Decision despatched
Fees paidRenewal fee
11.02.2015Renewal fee patent year 03
10.02.2016Renewal fee patent year 04
10.02.2017Renewal fee patent year 05
14.02.2018Renewal fee patent year 06
13.02.2019Renewal fee patent year 07
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.02.2013
AL18.12.2019
AT18.12.2019
CY18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
MK18.12.2019
MT18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
TR18.12.2019
LU15.02.2020
CH29.02.2020
LI29.02.2020
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
[2022/32]
Former [2022/27]HU15.02.2013
AL18.12.2019
AT18.12.2019
CY18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
MT18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
TR18.12.2019
LU15.02.2020
CH29.02.2020
LI29.02.2020
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2022/26]AL18.12.2019
AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
TR18.12.2019
LU15.02.2020
CH29.02.2020
LI29.02.2020
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2021/14]AL18.12.2019
AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
LU15.02.2020
CH29.02.2020
LI29.02.2020
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/51]AL18.12.2019
AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
LU15.02.2020
CH29.02.2020
LI29.02.2020
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/49]AL18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SK18.12.2019
SM18.12.2019
LU15.02.2020
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/47]AL18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SK18.12.2019
SM18.12.2019
LU15.02.2020
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/40]AL18.12.2019
CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/37]AL18.12.2019
CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
PT13.05.2020
Former [2020/36]AL18.12.2019
CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
PT13.05.2020
Former [2020/35]AL18.12.2019
CZ18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/32]AL18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/25]FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/23]FI18.12.2019
LT18.12.2019
LV18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/22]FI18.12.2019
LT18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
Former [2020/21]NO18.03.2020
Documents cited:Search[XP]WO2012104277  (NANOBIOTIX [FR], et al) [XP] 1-23 * page 15, paragraphs 2-3 * * examples 3,4 *;
 [X]WO2011109334  (UNIV CALIFORNIA [US], et al) [X] 1-23 * paragraphs [0204] , [0221] , [0222] , [0223] , [0227]; figures 9-11,15,16; example 6 *;
 [XY]WO2007024826  (CELSION CORP [US], et al) [X] 1-6,23 * example 1 * [Y] 7-22;
 [Y]  - HARAN G. ET AL., "Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases", BIOCHIM. BIOPHYS. ACTA, (1993), vol. 1151, pages 201 - 215, XP002740222 [Y] 7-22 * tables I,II *

DOI:   http://dx.doi.org/10.1016/0005-2736(93)90105-9
International search[X]US6726925  (NEEDHAM DAVID [US]);
 [Y]US2006222694  (OH CHOON K [US], et al);
 [Y]US2001033861  (LASIC DANILO D [US], et al);
 [Y]US2007269502  (PLIURA DIANA H [CA], et al);
 [Y]US5008380  (PALLADINO GAETANO [IT], et al);
 [Y]US2008261913  (SOMMADOSSI JEAN-PIERRE [US], et al)
Examination   - DE SMET M. ET AL., "Temperature-sensitive liposomes for doxorubicin delivery under MRI guidance", JOURNAL OF CONTROLLED RELEASE, (2010), vol. 143, pages 120 - 127, XP026964330
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