EP2872620 - DERIVATION AND SELF-RENEWAL OF ISI1+ CELLS AND USES THEREOF [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 20.11.2020 Database last updated on 02.09.2024 | |
Former | The patent has been granted Status updated on 13.12.2019 | ||
Former | Grant of patent is intended Status updated on 11.08.2019 | ||
Former | Examination is in progress Status updated on 21.11.2016 | Most recent event Tooltip | 08.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 10.08.2022 [2022/32] | Applicant(s) | For all designated states IsletOne AB Backvindeln 9 129 42 Hägersten / SE | [2015/39] |
Former [2015/21] | For all designated states IsletOne AB Backvindeln 9 129 42 Hägersten / SE | ||
For all designated states Grinnemo, Karl-Henrik Backvindeln 9 129 42 Hägersten / SE | |||
For all designated states Simonson, Oscar Gyllenstiernsgatan 20 115 26 Stockholm / SE | |||
For all designated states Corbascio, Matthias Hällmarksvägen 49 186 53 Vallentuna / SE | |||
For all designated states Sylvén, Christer Rånövägen 22 168 39 Bromma / SE | |||
For all designated states Wärdell, Eva Viktoriavägen 5 125 34 Älvsjö / SE | Inventor(s) | 01 /
GRINNEMO, Karl-Henrik Backvindeln 9 SE-129 42 Hägersten / SE | 02 /
SIMONSON, Oscar Gyllenstiernsgatan 20 SE-115 26 Stockholm / SE | 03 /
CORBASCIO, Matthias Hällmarksvägen 49 SE-186 53 Vallentuna / SE | 04 /
SYLVÉN, Christer Rånövägen 22 SE-168 39 Bromma / SE | 05 /
WÄRDELL, Eva Viktoriavägen 5 SE-125 34 Älvsjö / SE | [2015/21] | Representative(s) | Novitas Patent AB P.O. Box 55557 102 04 Stockholm / SE | [2015/21] | Application number, filing date | 13753363.4 | 11.07.2013 | [2020/03] | WO2013SE00112 | Priority number, date | US201261670640P | 12.07.2012 Original published format: US 201261670640 P | [2015/21] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2014011095 | Date: | 16.01.2014 | Language: | EN | [2014/03] | Type: | A1 Application with search report | No.: | EP2872620 | Date: | 20.05.2015 | Language: | EN | The application published by WIPO in one of the EPO official languages on 16.01.2014 takes the place of the publication of the European patent application. | [2015/21] | Type: | B1 Patent specification | No.: | EP2872620 | Date: | 15.01.2020 | Language: | EN | [2020/03] | Search report(s) | International search report - published on: | EP | 16.01.2014 | Classification | IPC: | C12N5/077, A61K35/34, C12N5/0775 | [2019/19] | CPC: |
C12N5/0657 (EP,US);
A61K35/34 (US);
C12N5/0668 (EP,US);
C12N2501/40 (US);
C12N2501/415 (EP,US);
C12N2533/52 (EP,US)
|
Former IPC [2015/21] | C12N5/0735, C12N5/071 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/21] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | ERHALT UND SELBSTERNEUERUNG VON LSL1+ ZELLEN UND DEREN VERWENDUNG | [2019/19] | English: | DERIVATION AND SELF-RENEWAL OF ISI1+ CELLS AND USES THEREOF | [2015/21] | French: | DÉRIVATION ET AUTO-RENOUVELLEMENT DES CELLULES LSL1+ ET LEUR UTILISATION | [2019/19] |
Former [2015/21] | ABLEITUNG UND SELBSTERNEUERUNG VON ISI1+-ZELLEN UND VERWENDUNG DAVON | ||
Former [2015/21] | DÉRIVATION ET AUTO-RENOUVELLEMENT DE CELLULES ISI1+ ET LEURS UTILISATIONS | Entry into regional phase | 10.02.2015 | National basic fee paid | 10.02.2015 | Designation fee(s) paid | 10.02.2015 | Examination fee paid | Examination procedure | 10.02.2015 | Examination requested [2015/21] | 22.10.2015 | Amendment by applicant (claims and/or description) | 13.05.2016 | Despatch of a communication from the examining division (Time limit: M06) | 17.11.2016 | Reply to a communication from the examining division | 11.07.2017 | Despatch of a communication from the examining division (Time limit: M06) | 17.01.2018 | Reply to a communication from the examining division | 27.06.2018 | Despatch of a communication from the examining division (Time limit: M01) | 24.07.2018 | Reply to a communication from the examining division | 02.04.2019 | Despatch of a communication from the examining division (Time limit: M01) | 03.04.2019 | Reply to a communication from the examining division | 12.08.2019 | Communication of intention to grant the patent | 04.12.2019 | Fee for grant paid | 04.12.2019 | Fee for publishing/printing paid | 04.12.2019 | Receipt of the translation of the claim(s) | 29.01.2020 | Request for correction of the decision to grant filed | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 13.05.2016 | Opposition(s) | 16.10.2020 | No opposition filed within time limit [2020/52] | Fees paid | Renewal fee | 09.07.2015 | Renewal fee patent year 03 | 11.07.2016 | Renewal fee patent year 04 | 29.06.2017 | Renewal fee patent year 05 | 30.07.2018 | Renewal fee patent year 06 | 25.06.2019 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 11.07.2013 | AL | 15.01.2020 | AT | 15.01.2020 | CY | 15.01.2020 | CZ | 15.01.2020 | EE | 15.01.2020 | FI | 15.01.2020 | HR | 15.01.2020 | LT | 15.01.2020 | LV | 15.01.2020 | MC | 15.01.2020 | MK | 15.01.2020 | MT | 15.01.2020 | RO | 15.01.2020 | RS | 15.01.2020 | SI | 15.01.2020 | SK | 15.01.2020 | SM | 15.01.2020 | TR | 15.01.2020 | BG | 15.04.2020 | NO | 15.04.2020 | GR | 16.04.2020 | IS | 15.05.2020 | IE | 11.07.2020 | LU | 11.07.2020 | BE | 31.07.2020 | [2022/31] |
Former [2022/30] | HU | 11.07.2013 | |
AL | 15.01.2020 | ||
AT | 15.01.2020 | ||
CY | 15.01.2020 | ||
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
MC | 15.01.2020 | ||
MT | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
TR | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
IE | 11.07.2020 | ||
LU | 11.07.2020 | ||
BE | 31.07.2020 | ||
Former [2022/27] | HU | 11.07.2013 | |
AT | 15.01.2020 | ||
CY | 15.01.2020 | ||
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
MC | 15.01.2020 | ||
MT | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
TR | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
IE | 11.07.2020 | ||
LU | 11.07.2020 | ||
BE | 31.07.2020 | ||
Former [2022/26] | AT | 15.01.2020 | |
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
MC | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
TR | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
IE | 11.07.2020 | ||
LU | 11.07.2020 | ||
BE | 31.07.2020 | ||
Former [2021/37] | AT | 15.01.2020 | |
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
MC | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
IE | 11.07.2020 | ||
LU | 11.07.2020 | ||
BE | 31.07.2020 | ||
Former [2021/24] | AT | 15.01.2020 | |
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
MC | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
LU | 11.07.2020 | ||
BE | 31.07.2020 | ||
Former [2021/20] | AT | 15.01.2020 | |
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
MC | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
LU | 11.07.2020 | ||
Former [2021/13] | AT | 15.01.2020 | |
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
MC | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
Former [2021/11] | AT | 15.01.2020 | |
CZ | 15.01.2020 | ||
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SI | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
Former [2020/50] | CZ | 15.01.2020 | |
EE | 15.01.2020 | ||
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
Former [2020/49] | CZ | 15.01.2020 | |
FI | 15.01.2020 | ||
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SK | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
Former [2020/48] | FI | 15.01.2020 | |
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
RO | 15.01.2020 | ||
RS | 15.01.2020 | ||
SM | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
Former [2020/47] | FI | 15.01.2020 | |
HR | 15.01.2020 | ||
LT | 15.01.2020 | ||
LV | 15.01.2020 | ||
RS | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
Former [2020/40] | FI | 15.01.2020 | |
HR | 15.01.2020 | ||
LV | 15.01.2020 | ||
RS | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
IS | 15.05.2020 | ||
Former [2020/39] | FI | 15.01.2020 | |
HR | 15.01.2020 | ||
LV | 15.01.2020 | ||
RS | 15.01.2020 | ||
BG | 15.04.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
Former [2020/38] | FI | 15.01.2020 | |
HR | 15.01.2020 | ||
LV | 15.01.2020 | ||
RS | 15.01.2020 | ||
NO | 15.04.2020 | ||
GR | 16.04.2020 | ||
Former [2020/37] | FI | 15.01.2020 | |
HR | 15.01.2020 | ||
LV | 15.01.2020 | ||
RS | 15.01.2020 | ||
NO | 15.04.2020 | ||
Former [2020/35] | FI | 15.01.2020 | |
NO | 15.04.2020 | Cited in | International search | [Y]WO2007016366 (UNIV YALE [US], et al) [Y] 1-21* claims 12,12,45,47 *; | [Y]WO2008094597 (UNIV GEORGIA RES FOUND [US], et al) [Y] 1-21 * page 39; figure 13 *; | [X]WO2010011352 (UNIV GEORGIA RES FOUND [US], et al) [X] 1-21 * abstract *; | [X]US2011305672 (DALTON STEPHEN [US], et al) [X] 1-21 * paragraphs [0003] , [0203] , [0335] *; | [Y] - GENEAD R ET AL, "Early first trimester human embryonic cardiac Islet-1 progenitor cells and cardiomyocytes: Immunohistochemical and electrophysiological characterization", STEM CELL RESEARCH, ELSEVIER, NL, vol. 4, no. 1, ISSN 1873-5061, (20100101), pages 69 - 76, (20091106), XP026829842 [Y] 1-21 * page 70, column 1, paragraph 2 * | [Y] - LAUGWITZ KARL-LUDWIG ET AL, "Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE (AND SUPPLEMENTARY INFORMATION), NATURE PUBLISHING GROUP, UNITED KINGDOM, (20050210), vol. 433, no. 7026, doi:10.1038/NATURE03215, ISSN 0028-0836, pages 647 - 653, XP002477756 [Y] 1-21 * page 652; figure 2 * DOI: http://dx.doi.org/10.1038/nature03215 | [Y] - GENEAD RAMI ET AL, "Islet-1 cells are cardiac progenitors present during the entire lifespan: from the embryonic stage to adulthood.", STEM CELLS AND DEVELOPMENT OCT 2010, (201010), vol. 19, no. 10, ISSN 1557-8534, pages 1601 - 1615, XP009174175 [Y] 1-21 * page 1611, column 2, paragraph 1 * DOI: http://dx.doi.org/10.1089/scd.2009.0483 | [Y] - KLAUS ALEXANDRA ET AL, "Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (20120501), vol. 109, no. 27, ISSN 0027-8424, pages 10921 - 10926, XP009174150 [Y] 1-21 * figures 2-4 * DOI: http://dx.doi.org/10.1073/pnas.1121236109 | [Y] - MITTAL ASHOK ET AL, "Fibronectin and integrin alpha 5 play essential roles in the development of the cardiac neural crest", MECHANISMS OF DEVELOPMENT, (201009), vol. 127, no. 9-12, ISSN 0925-4773, pages 472 - 484, XP009174149 [Y] 1-21 * the whole document * DOI: http://dx.doi.org/10.1016/j.mod.2010.08.005 | Examination | WO2005046596 | - DOMOGATSKAYA ANNA ET AL, "Laminin-511 but not -332, -111, or -411 enables mouse embryonic stem cell self-renewal in vitro", STEM CELLS, ALPHAMED PRESS, INC, UNITED STATES, (20081101), vol. 26, no. 11, doi:10.1634/STEMCELLS.2007-0389, ISSN 1549-4918, pages 2800 - 2809, XP009109423 DOI: http://dx.doi.org/10.1634/stemcells.2007-0389 | by applicant | - GENEAD ET AL., PLOSONE, (2012), vol. 7, page E36804 | - LAM ET AL., PEDIATR. CARDIOL., (2009), vol. 30, page 690 | - LAUGWITZ ET AL., NATURE, (2005), vol. 433, page 647 | - WESTGREN ET AL., ACTA SCAND OBSTET GYNECOL, (1994), vol. 73, pages 601 - 604 |