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Extract from the Register of European Patents

EP About this file: EP2900254

EP2900254 - ALPHA-1-MICROGLOBULIN FOR USE IN THE TREATMENT OF MITOCHONDRIA-RELATED DISEASES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.06.2017
Database last updated on 21.01.2025
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
A1M Pharma AB
Scheelevägen 22
223 63 Lund / SE
[2016/22]
Former [2015/32]For all designated states
A1M Pharma AB
Medicon Village
223 81 Lund / SE
Inventor(s)01 / AKERSTRÖM, Bo
Skördevägen 3
S-227 38 Lund / SE
02 / GRAM, Magnus
Marietorpsgården
Tegelbruksvägen 250
S-238 39 Oxie / SE
03 / ROSENLÖF, Lena
Osbyholm Banvallsvägen 17
S-242 93 Hörby / SE
 [2016/31]
Former [2015/32]01 / AKERSTRÖM, Bo
Skördevägen 3
S-227 38 Lund / SE
02 / GRAM, Magnus
Marietorpsgården
Tegelbruksvägen 250
S-238 39 Oxie / SE
03 / ROSENLÖF, Lena
OsbyholmBanvallsvägen 17
S-242 93 Hörby / SE
Representative(s)Chas. Hude A/S
Langebrogade 3B
1411 Copenhagen K / DK
[N/P]
Former [2015/32]Chas. Hude A/S
H.C. Andersens Boulevard 33
1780 Copenhagen V / DK
Application number, filing date13759995.704.09.2013
[2016/31]
WO2013EP68270
Priority number, dateDK2012007053805.09.2012         Original published format: DK 201270538
DK2012007055712.09.2012         Original published format: DK 201270557
[2015/32]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014037390
Date:13.03.2014
Language:EN
[2014/11]
Type: A1 Application with search report 
No.:EP2900254
Date:05.08.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 13.03.2014 takes the place of the publication of the European patent application.
[2015/32]
Type: B1 Patent specification 
No.:EP2900254
Date:03.08.2016
Language:EN
[2016/31]
Search report(s)International search report - published on:EP13.03.2014
ClassificationIPC:A61K38/17, A61P43/00, A61K38/00
[2015/32]
CPC:
A61K38/1722 (EP,US); A61K38/17 (EP,US); A61P1/04 (EP);
A61P11/00 (EP); A61P13/02 (EP); A61P25/00 (EP);
A61P25/08 (EP); A61P25/14 (EP); A61P25/28 (EP);
A61P27/02 (EP); A61P3/00 (EP); A61P3/02 (EP);
A61P43/00 (EP); A61P9/00 (EP); A61P9/10 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/32]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:ALPHA-1-MICROGLOBULIN ZUR VERWENDUNG BEI DER BEHANDLUNG VON MITOCHONDRIEN-ASSOZIIERTEN ERKRANKUNGEN[2015/32]
English:ALPHA-1-MICROGLOBULIN FOR USE IN THE TREATMENT OF MITOCHONDRIA-RELATED DISEASES[2015/32]
French:ALPHA-1-MICROGLOBULINE DESTINÉE À ÊTRE UTILISÉE DANS LE TRAITEMENT DE MALADIES ASSOCIÉES AUX MITOCHONDRIES[2015/32]
Entry into regional phase13.03.2015National basic fee paid 
13.03.2015Designation fee(s) paid 
13.03.2015Examination fee paid 
Examination procedure24.03.2014Request for preliminary examination filed
International Preliminary Examining Authority: EP
13.03.2015Examination requested  [2015/32]
15.03.2016Despatch of a communication from the examining division (Time limit: M04)
05.04.2016Reply to a communication from the examining division
13.05.2016Communication of intention to grant the patent
21.06.2016Fee for grant paid
21.06.2016Fee for publishing/printing paid
21.06.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.03.2016
Opposition(s)04.05.2017No opposition filed within time limit [2017/28]
Fees paidRenewal fee
14.09.2015Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL03.08.2016
CY03.08.2016
EE03.08.2016
LT03.08.2016
LV03.08.2016
MC03.08.2016
MK03.08.2016
RS03.08.2016
SI03.08.2016
SK03.08.2016
SM03.08.2016
LU04.09.2016
MT30.09.2016
BG03.11.2016
GR04.11.2016
IS03.12.2016
[2018/46]
Former [2018/32]CY03.08.2016
EE03.08.2016
LT03.08.2016
LV03.08.2016
MC03.08.2016
MK03.08.2016
RS03.08.2016
SI03.08.2016
SK03.08.2016
SM03.08.2016
LU04.09.2016
MT30.09.2016
BG03.11.2016
GR04.11.2016
IS03.12.2016
Former [2017/40]EE03.08.2016
LT03.08.2016
LV03.08.2016
MC03.08.2016
RS03.08.2016
SI03.08.2016
SK03.08.2016
SM03.08.2016
LU04.09.2016
BG03.11.2016
GR04.11.2016
IS03.12.2016
Former [2017/37]EE03.08.2016
LT03.08.2016
LV03.08.2016
MC03.08.2016
RS03.08.2016
SI03.08.2016
SK03.08.2016
SM03.08.2016
BG03.11.2016
GR04.11.2016
IS03.12.2016
Former [2017/32]EE03.08.2016
LT03.08.2016
LV03.08.2016
MC03.08.2016
RS03.08.2016
SK03.08.2016
SM03.08.2016
BG03.11.2016
GR04.11.2016
IS03.12.2016
Former [2017/13]LT03.08.2016
LV03.08.2016
RS03.08.2016
GR04.11.2016
IS03.12.2016
Former [2017/11]LT03.08.2016
RS03.08.2016
GR04.11.2016
IS03.12.2016
Former [2017/07]LT03.08.2016
Cited inInternational search[A]WO2010006809  (AKERSTROEM BO [SE], et al) [A] 1-6 * page 31 - page 38 *;
 [XP]  - OLSSON MAGNUS G ET AL, The Radical-Binding Lipocalin A1M Binds to a Complex I Subunit and Protects Mitochondrial Structure and Function., ANTIOXIDANTS & REDOX SIGNALING 1 JUN 2013, VOL. 18, NR. 16, PAGE(S) 2017 - 2028, (20130104), ISSN 1557-7716, XP002696477 [XP] 1-6 * the whole document *

DOI:   http://dx.doi.org/10.1089/ars.2012.4658
 [AD]  - OLSSON MAGNUS G ET AL, Pathological conditions involving extracellular hemoglobin: molecular mechanisms, clinical significance, and novel therapeutic opportunities for [alpha](1)-microglobulin., ANTIOXIDANTS & REDOX SIGNALING 1 SEP 2012, VOL. 17, NR. 5, PAGE(S) 813 - 846, (20120901), ISSN 1557-7716, XP002696478 [AD] 1-6 * the whole document *

DOI:   http://dx.doi.org/10.1089/ars.2011.4282
 [AD]  - MAY K ET AL, "Perfusion of human placenta with hemoglobin introduces preeclampsia-like injuries that are prevented by-microglobulin", PLACENTA, W.B. SAUNDERS, GB, vol. 32, no. 4, doi:10.1016/J.PLACENTA.2011.01.017, ISSN 0143-4004, (20110131), pages 323 - 332, (20110207), XP028165366 [AD] 1-6 * abstract *

DOI:   http://dx.doi.org/10.1016/j.placenta.2011.01.017
 [A]  - ÂKERSTRÖM BO ET AL, "The lipocalin alpha1-microglobulin has radical scavenging properties", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 282, doi:10.1074/JBC.M702624200, ISSN 0021-9258, (20070101), pages 31493 - 31503, (20070831), XP002516419 [A] 1-6 * abstract *

DOI:   http://dx.doi.org/10.1074/JBC.M702624200
 [AD]  - OLSSON M G ET AL, "THE LIPOCALIN ALPHA1-MICROGLOBULIN PROTECTS ERYTHROID K562 CELLS AGAINST OXIDATIVE DAMAGE INDUCED BY HEME AND REACTIVE OXYGEN SPECIES", FREE RADICAL RESEARCH, YVERDON, CH, (20080801), vol. 42, no. 8, doi:10.1080/10715760802337265, ISSN 1071-5762, pages 725 - 736, XP008102557 [AD] 1-6 * abstract *

DOI:   http://dx.doi.org/10.1080/10715760802337265
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.