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Extract from the Register of European Patents

EP About this file: EP2831079

EP2831079 - BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.06.2018
Database last updated on 02.08.2024
FormerThe patent has been granted
Status updated on  14.07.2017
FormerGrant of patent is intended
Status updated on  02.03.2017
FormerExamination is in progress
Status updated on  02.12.2016
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Agency for Science, Technology and Research
1 Fusionopolis Way 20-10 Connexis
Singapore 138632 / SG
[2015/06]
Inventor(s)01 / NACRO, Kassoum
c/o Experimental Therapeutic Centre
31 Biopolis Way
Nanos
03-01
Singapore 138669 / SG
02 / DURAISWAMY, Athisayamani, Jeyaraj
c/o Experimental Therapeutic Centre
31 Biopolis Way
Nanos
03-01
Singapore 138669 / SG
03 / CHENNAMANENI, Lohitha, Rao
c/o Institute of Chemical and Engineering Sciences
(ICES), A*STAR
8 Biomedical Grove
Neuros, No. 07-01
Singapore 138665 / SG
 [2017/33]
Former [2015/06]01 / NACRO, Kassoum
c/o Experimental Therapeutic Centre
31 Biopolis Way
Nanos
03-01
Singapore 138669 / SG
02 / DURAISWAMY, Athisayamani, Jeyaraj
c/o Experimental Therapeutic Centre
31 Biopolis Way
Nanos
03-01
Singapore 138669 / SG
03 / CHENNAMANENI, Lohitha, Rao
c/o Institute of Chemical and Engineering Sciences
1 Pesek Road
Jurong Island
Singapore 627833 / SG
Representative(s)HGF
Delta House
50 West Nile Street
Glasgow G1 2NP / GB
[N/P]
Former [2017/33]HGF Limited
Delta House
50 West Nile Street
Glasgow G1 2NP / GB
Former [2015/06]Wilson, Gary
HGF Limited
Delta House
50 West Nile Street
Glasgow G1 2NP / GB
Application number, filing date13768800.801.04.2013
[2017/33]
WO2013SG00126
Priority number, dateGB2012000566930.03.2012         Original published format: GB 201205669
[2015/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013147711
Date:03.10.2013
Language:EN
[2013/40]
Type: A1 Application with search report 
No.:EP2831079
Date:04.02.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 03.10.2013 takes the place of the publication of the European patent application.
[2015/06]
Type: B1 Patent specification 
No.:EP2831079
Date:16.08.2017
Language:EN
[2017/33]
Search report(s)International search report - published on:AU03.10.2013
(Supplementary) European search report - dispatched on:EP16.10.2015
ClassificationIPC:C07D487/04, C07D265/06, A61K31/519, A61K31/5025, A61P35/00, A61P3/10
[2015/06]
CPC:
C07D487/04 (EP,CN,US); A61K31/4184 (EP,US); A61K31/437 (EP,US);
A61K31/4545 (EP,US); A61K31/496 (EP,US); A61K31/4985 (EP,US);
A61K31/5025 (EP,US); A61K31/519 (EP,US); A61K31/5377 (EP,US);
A61K31/551 (EP,US); A61K31/553 (EP,US); A61K45/06 (EP,US);
A61P35/00 (EP,US); C07D235/06 (EP,CN,US); C07D471/04 (EP,CN,US);
C07D471/10 (EP,CN,US); C07D491/107 (EP,CN,US); C07D519/00 (EP,CN,US) (-)
C-Set:
A61K31/4184, A61K2300/00 (EP,US);
A61K31/437, A61K2300/00 (US,EP);
A61K31/4985, A61K2300/00 (US,EP);
A61K31/5025, A61K2300/00 (US,EP);
A61K31/519, A61K2300/00 (EP,US)
(-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/06]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:BICYCLISCHE/HETEROCYCLISCHE DERIVATE ALS MNK1- UND MNK2-MODULATOREN SOWIE VERWENDUNGEN DAVON[2015/06]
English:BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF[2015/06]
French:DÉRIVÉS HÉTÉROCYCLIQUES BICYCLIQUES À TITRE DE MODULATEURS DE MNK1 ET MNK2 ET LEURS UTILISATIONS[2015/06]
Entry into regional phase16.10.2014National basic fee paid 
16.10.2014Search fee paid 
16.10.2014Designation fee(s) paid 
16.10.2014Examination fee paid 
Examination procedure30.01.2014Request for preliminary examination filed
International Preliminary Examining Authority: AU
16.10.2014Examination requested  [2015/06]
12.05.2016Amendment by applicant (claims and/or description)
25.07.2016Despatch of a communication from the examining division (Time limit: M04)
30.11.2016Reply to a communication from the examining division
03.03.2017Communication of intention to grant the patent
30.06.2017Fee for grant paid
30.06.2017Fee for publishing/printing paid
30.06.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17179630.3  / EP3321268
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  25.07.2016
Opposition(s)17.05.2018No opposition filed within time limit [2018/30]
Fees paidRenewal fee
27.02.2015Renewal fee patent year 03
21.03.2016Renewal fee patent year 04
28.03.2017Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU01.04.2013
AL16.08.2017
CY16.08.2017
CZ16.08.2017
EE16.08.2017
HR16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
MK16.08.2017
PT16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
TR16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
IE01.04.2018
LU01.04.2018
MT01.04.2018
[2020/34]
Former [2020/31]HU01.04.2013
CY16.08.2017
CZ16.08.2017
EE16.08.2017
HR16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
MK16.08.2017
PT16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
TR16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
IE01.04.2018
LU01.04.2018
MT01.04.2018
Former [2020/30]HU01.04.2013
CZ16.08.2017
EE16.08.2017
HR16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
PT16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
TR16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
IE01.04.2018
LU01.04.2018
MT01.04.2018
Former [2020/28]HU01.04.2013
CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
PT16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
TR16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
IE01.04.2018
LU01.04.2018
MT01.04.2018
Former [2020/16]CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
TR16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
IE01.04.2018
LU01.04.2018
MT01.04.2018
Former [2020/08]CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
IE01.04.2018
LU01.04.2018
MT01.04.2018
Former [2019/19]CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
IE01.04.2018
LU01.04.2018
Former [2019/08]CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
LU01.04.2018
Former [2018/52]CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
MC16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
Former [2018/39]CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
RO16.08.2017
RS16.08.2017
SI16.08.2017
SK16.08.2017
SM16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
Former [2018/25]CZ16.08.2017
EE16.08.2017
LT16.08.2017
LV16.08.2017
RO16.08.2017
RS16.08.2017
SK16.08.2017
SM16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
Former [2018/21]CZ16.08.2017
LT16.08.2017
LV16.08.2017
RS16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
Former [2018/12]LT16.08.2017
LV16.08.2017
RS16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
Former [2018/11]LT16.08.2017
RS16.08.2017
BG16.11.2017
GR17.11.2017
IS16.12.2017
Former [2018/07]LT16.08.2017
Documents cited:Search[XI]WO2012013713  (BAYER PHARMA AG [DE], et al);
International search[X]WO2008078091  (ASTEX THERAPEUTICS LTD [GB], et al);
 [Y]WO2010055072  (NOVARTIS FORSCHUNGSSTIFTUNG [CH], et al);
 [X]US2012058997  (XU YONG [US], et al);
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.