EP2920175 - TRIAZOLOPYRIDAZINE DERIVATIVES AS BROMODOMAIN INHIBITORS [Right-click to bookmark this link] | |||
Former [2015/39] | TRIAZOLOPYRIDAZINE | ||
[2018/43] | Status | No opposition filed within time limit Status updated on 30.08.2019 Database last updated on 31.08.2024 | |
Former | The patent has been granted Status updated on 21.09.2018 | ||
Former | Grant of patent is intended Status updated on 27.05.2018 | Most recent event Tooltip | 03.07.2020 | Lapse of the patent in a contracting state New state(s): CY, HU, MK | published on 05.08.2020 [2020/32] | Applicant(s) | For all designated states Boehringer Ingelheim International GmbH Binger Strasse 173 55216 Ingelheim am Rhein / DE | [2018/43] |
Former [2015/39] | For all designated states Boehringer Ingelheim International GmbH Binger Strasse 173 55216 Ingelheim am Rhein / DE | Inventor(s) | 01 /
ENGELHARDT, Harald BOEHRINGER INGELHEIM GMBH Corporate Patents Binger Strasse 173 55216 Ingelheim Am Rhein / DE | 02 /
SMETHURST, Christian BOEHRINGER INGELHEIM GMBH Corporate Patents Binger Strasse 173 55216 Ingelheim Am Rhein / DE | 03 /
STEFFEN, Andreas BOEHRINGER INGELHEIM GMBH Corporate Patents Binger Strasse 173 55216 Ingelheim Am Rhein / DE | 04 /
REISER, Ulrich BOEHRINGER INGELHEIM GMBH Corporate Patents Binger Strasse 173 55216 Ingelheim Am Rhein / DE | 05 /
KESSLER, Dirk BOEHRINGER INGELHEIM GMBH Corporate Patents Binger Strasse 173 55216 Ingelheim Am Rhein / DE | 06 /
GIANNI, Davide BOEHRINGER INGELHEIM GMBH Corporate Patents Binger Strasse 173 55216 Ingelheim Am Rhein / DE | [2015/39] | Representative(s) | Simon, Elke Anna Maria, et al Boehringer Ingelheim GmbH Binger Strasse 173 55216 Ingelheim am Rhein / DE | [2015/39] | Application number, filing date | 13791802.5 | 13.11.2013 | [2015/39] | WO2013EP73758 | Priority number, date | EP20120192452 | 13.11.2012 Original published format: EP 12192452 | [2015/39] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2014076146 | Date: | 22.05.2014 | Language: | EN | [2014/21] | Type: | A1 Application with search report | No.: | EP2920175 | Date: | 23.09.2015 | Language: | EN | The application published by WIPO in one of the EPO official languages on 22.05.2014 takes the place of the publication of the European patent application. | [2015/39] | Type: | B1 Patent specification | No.: | EP2920175 | Date: | 24.10.2018 | Language: | EN | [2018/43] | Search report(s) | International search report - published on: | EP | 22.05.2014 | Classification | IPC: | C07D487/04, A61K31/5025 | [2015/39] | CPC: |
C07D487/04 (EP,US);
A61K31/5025 (EP,US);
A61K45/06 (EP,US);
A61P35/00 (EP)
| C-Set: |
A61K31/5025, A61K2300/00 (EP,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/39] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | TRIAZOLOPYRIDAZINDERIVATE ALS BROMODOMAINHEMMER | [2018/43] | English: | TRIAZOLOPYRIDAZINE DERIVATIVES AS BROMODOMAIN INHIBITORS | [2018/43] | French: | DÉRIVÉS DE TRIAZOLOPYRIDAZINE COMME INHIBITEURS DE BROMODOMAINE | [2018/43] |
Former [2015/39] | TRIAZOLPYRIDAZIN | ||
Former [2015/39] | TRIAZOLOPYRIDAZINE | ||
Former [2015/39] | DÉRIVÉS TRIAZOLOPYRIDAZINES | Entry into regional phase | 15.06.2015 | National basic fee paid | 15.06.2015 | Designation fee(s) paid | 15.06.2015 | Examination fee paid | Examination procedure | 15.06.2015 | Examination requested [2015/39] | 22.12.2015 | Amendment by applicant (claims and/or description) | 25.02.2016 | Despatch of a communication from the examining division (Time limit: M04) | 05.07.2016 | Reply to a communication from the examining division | 28.05.2018 | Communication of intention to grant the patent | 17.09.2018 | Fee for grant paid | 17.09.2018 | Fee for publishing/printing paid | 17.09.2018 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 25.02.2016 | Opposition(s) | 25.07.2019 | No opposition filed within time limit [2019/40] | Fees paid | Renewal fee | 30.11.2015 | Renewal fee patent year 03 | 30.11.2016 | Renewal fee patent year 04 | 30.11.2017 | Renewal fee patent year 05 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 13.11.2013 | AL | 24.10.2018 | AT | 24.10.2018 | CY | 24.10.2018 | CZ | 24.10.2018 | DK | 24.10.2018 | EE | 24.10.2018 | ES | 24.10.2018 | FI | 24.10.2018 | HR | 24.10.2018 | IT | 24.10.2018 | LT | 24.10.2018 | LV | 24.10.2018 | MC | 24.10.2018 | MK | 24.10.2018 | NL | 24.10.2018 | PL | 24.10.2018 | RO | 24.10.2018 | RS | 24.10.2018 | SE | 24.10.2018 | SI | 24.10.2018 | SK | 24.10.2018 | SM | 24.10.2018 | TR | 24.10.2018 | IE | 13.11.2018 | LU | 13.11.2018 | MT | 13.11.2018 | BE | 30.11.2018 | CH | 30.11.2018 | LI | 30.11.2018 | BG | 24.01.2019 | NO | 24.01.2019 | GR | 25.01.2019 | IS | 24.02.2019 | PT | 24.02.2019 | [2020/31] |
Former [2020/17] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
CZ | 24.10.2018 | ||
DK | 24.10.2018 | ||
EE | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
MC | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RO | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
SI | 24.10.2018 | ||
SK | 24.10.2018 | ||
SM | 24.10.2018 | ||
TR | 24.10.2018 | ||
IE | 13.11.2018 | ||
LU | 13.11.2018 | ||
MT | 13.11.2018 | ||
BE | 30.11.2018 | ||
CH | 30.11.2018 | ||
LI | 30.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2020/08] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
CZ | 24.10.2018 | ||
DK | 24.10.2018 | ||
EE | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
MC | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RO | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
SI | 24.10.2018 | ||
SK | 24.10.2018 | ||
SM | 24.10.2018 | ||
IE | 13.11.2018 | ||
LU | 13.11.2018 | ||
MT | 13.11.2018 | ||
BE | 30.11.2018 | ||
CH | 30.11.2018 | ||
LI | 30.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/50] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
CZ | 24.10.2018 | ||
DK | 24.10.2018 | ||
EE | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
MC | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RO | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
SI | 24.10.2018 | ||
SK | 24.10.2018 | ||
SM | 24.10.2018 | ||
IE | 13.11.2018 | ||
LU | 13.11.2018 | ||
BE | 30.11.2018 | ||
CH | 30.11.2018 | ||
LI | 30.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/48] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
CZ | 24.10.2018 | ||
DK | 24.10.2018 | ||
EE | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
MC | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RO | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
SK | 24.10.2018 | ||
SM | 24.10.2018 | ||
IE | 13.11.2018 | ||
LU | 13.11.2018 | ||
CH | 30.11.2018 | ||
LI | 30.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/40] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
CZ | 24.10.2018 | ||
DK | 24.10.2018 | ||
EE | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
MC | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RO | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
SK | 24.10.2018 | ||
SM | 24.10.2018 | ||
LU | 13.11.2018 | ||
CH | 30.11.2018 | ||
LI | 30.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/37] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
CZ | 24.10.2018 | ||
DK | 24.10.2018 | ||
EE | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
MC | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RO | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
SM | 24.10.2018 | ||
LU | 13.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/35] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
CZ | 24.10.2018 | ||
DK | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
LU | 13.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/34] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
DK | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
IT | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
LU | 13.11.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/26] | AL | 24.10.2018 | |
AT | 24.10.2018 | ||
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
PT | 24.02.2019 | ||
Former [2019/25] | AT | 24.10.2018 | |
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
RS | 24.10.2018 | ||
SE | 24.10.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
Former [2019/24] | AT | 24.10.2018 | |
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
SE | 24.10.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
GR | 25.01.2019 | ||
IS | 24.02.2019 | ||
Former [2019/23] | AT | 24.10.2018 | |
ES | 24.10.2018 | ||
FI | 24.10.2018 | ||
HR | 24.10.2018 | ||
LT | 24.10.2018 | ||
LV | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
IS | 24.02.2019 | ||
Former [2019/22] | FI | 24.10.2018 | |
LT | 24.10.2018 | ||
NL | 24.10.2018 | ||
PL | 24.10.2018 | ||
BG | 24.01.2019 | ||
NO | 24.01.2019 | ||
IS | 24.02.2019 | ||
Former [2019/21] | FI | 24.10.2018 | |
LT | 24.10.2018 | ||
NL | 24.10.2018 | ||
NO | 24.01.2019 | ||
IS | 24.02.2019 | ||
Former [2019/20] | LT | 24.10.2018 | |
NL | 24.10.2018 | ||
NO | 24.01.2019 | ||
Former [2019/17] | NL | 24.10.2018 | Cited in | International search | [A]GB1480621 (LEPETIT SPA) [A] 1* page 1 to page 2, column 2, line 19;; claim 1 *; | [A]WO2007075567 (JANSSEN PHARMACEUTICA NV [BE], et al) [A] 1-26 * claims 1,13,16-19 *; | [A]WO2008109104 (UNIV CALIFORNIA [US], et al) [A] 1-26 * claims 1-39 *; | [A]WO2011161031 (GLAXOSMITHKLINE LLC [US], et al) [A] 1-26 * claims 1,29-33,35-37,39 *; | [XP]WO2012174487 (CONSTELLATION PHARMACEUTICALS INC [US], et al) [XP] 1,2,10,20-26 * claims 1,2,5,6,20-30,32,33 *; | [X] - KATRUSIAK, ANNA ET AL., "Nucleophilic substitution and lipophilicity-structure relations in methylazolopyridazines", COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS., CZINSTITUTE OF ORGANIC CHEMISTRY & BIOCHEMISTRY, PRAGUE., (2005), vol. 70, no. 9, ISSN 0010-0765, pages 1372 - 1386, XP008160516 [X] 1,2,10 * page 1376, compound 18; page 1385, lines 3 to 6 * DOI: http://dx.doi.org/10.1135/cccc20051372 | by applicant | WO2011054553 | WO2011054846 | - YANG; ZHOU, MOL. CELL. BIOL., (2008), vol. 28, page 967 | - FRENCH ET AL., CANCER RES., (2003), vol. 63, page 304 | - ZUBER ET AL., NATURE, (2011), vol. 478, no. 7370, pages 524 - 8 | - LEROY, MOL. CELL, (2008), vol. 30, no. 1, pages 51 - 60 | - BIRGE, S.M. ET AL., J. PHARM. SCI., (1977), vol. 66, pages 1 - 19 | - TETRAHYDRON LETTERS, (2003), vol. 44, pages 41 - 43 |