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EP About this file: EP2858486

EP2858486 - METHODS AND COMPOSITIONS FOR GENERATING CONDITIONAL KNOCK-OUT ALLELES [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 20.07.2018 Database last updated on 18.01.2025
Former	Examination is in progress Status updated on 17.03.2017
Most recent event Tooltip	20.07.2018	Application deemed to be withdrawn	published on 22.08.2018 [2018/34]
Applicant(s)	For all designated states F. Hoffmann-La Roche AG Grenzacherstrasse 124 4070 Basel / CH
	[N/P]
Former [2015/16]	For all designated states F.Hoffmann-La Roche AG Grenzacherstrasse 124 4070 Basel / CH
Inventor(s)	01 / WARMING, Soren c/o Genentech Inc. 1 DNA Way South San Francisco California 94080 / US
	02 / ANDERSON, Keith R. c/o Genentech Inc. 1 DNA Way South San Francisco California 94080 / US
	[2015/16]
Representative(s)	Brodbeck, Michel, et al F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124 4070 Basel / CH
	[2015/16]
Application number, filing date	13804001.9	12.06.2013
	WO2013US45382
Priority number, date	US201261658670P	12.06.2012 Original published format: US 201261658670 P
	[2015/16]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2013188522
	Date:	19.12.2013
	Language:	EN
	[2013/51]
	Type:	A2 Application without search report
	No.:	EP2858486
	Date:	15.04.2015
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 19.12.2013 takes the place of the publication of the European patent application.
	[2015/16]
Search report(s)	International search report - published on:	US	10.04.2014
	(Supplementary) European search report - dispatched on:	EP	11.03.2016
Classification	IPC:	A01K67/00, A01K67/027, C12N15/00, C12N15/85, C12N15/90	[2016/15]
	CPC:	A01K67/0276 (EP,CN,KR,US); C12N15/102 (KR); C12N15/907 (KR,US); A01K67/027 (KR); C12N15/8509 (EP,CN,KR,US); C12N9/22 (KR); (+) A01K2217/075 (EP,CN,KR,US); A01K2227/105 (EP,CN,KR,US) (-)
	Former IPC [2015/16]	A01K67/00, A01K67/027, C12N15/00
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2015/16]
Title	German:	VERFAHREN UND ZUSAMMENSETZUNGEN ZUR ERZEUGUNG VON ALLELEN MIT KONDITIONELLEM KNOCKOUT	[2015/16]
	English:	METHODS AND COMPOSITIONS FOR GENERATING CONDITIONAL KNOCK-OUT ALLELES	[2015/16]
	French:	PROCÉDÉS ET COMPOSITIONS POUR LA GÉNÉRATION D'ALLÈLES À INACTIVATION CONDITIONNELLE	[2015/16]
Entry into regional phase	12.01.2015	National basic fee paid
	12.01.2015	Search fee paid
	12.01.2015	Designation fee(s) paid
	12.01.2015	Examination fee paid
Examination procedure	12.01.2015	Examination requested [2015/16]
	29.09.2016	Amendment by applicant (claims and/or description)
	21.03.2017	Despatch of a communication from the examining division (Time limit: M02)
	31.05.2017	Reply to a communication from the examining division
	03.11.2017	Despatch of a communication from the examining division (Time limit: M04)
	14.03.2018	Application deemed to be withdrawn, date of legal effect [2018/34]
	09.04.2018	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2018/34]
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 21.03.2017
Fees paid	Renewal fee
	05.06.2015	Renewal fee patent year 03
	31.03.2016	Renewal fee patent year 04
	08.06.2017	Renewal fee patent year 05
	02.07.2018	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A] - HILKKA TURAKAINEN ET AL, "Transposition-Based Method for the Rapid Generation of Gene-Targeting Vectors to Produce Cre/Flp-Modifiable Conditional Knock-Out Mice", PLOS ONE, (20090205), vol. 4, no. 2, doi:10.1371/journal.pone.0004341, page e4341, XP055253547 [A] 1-21 * the whole document * DOI: http://dx.doi.org/10.1371/journal.pone.0004341
	International search	[A]US2007218071 (MORRIS DAVID W [US], et al);
		[A]US2009092578 (SU HONGSHENG [CA], et al);
		[Y]US2009136507 (ALLEN KRISTINA [US], et al);
		[Y]US2011023143 (WEINSTEIN EDWARD [US], et al);
		[A] - XIE ET AL., "Cloning-Independent and Counterselectable Markerless Mutagenesis System in Streptococcus mutans.", APPL ENVIRON MICROBIOL., (2011), vol. 77, no. 22, pages 8025 - 33, XP055176926 DOI: http://dx.doi.org/10.1128/AEM.06362-11
		[A] - "Mus musculus chromosome 8, clone RP24-427K8, complete sequence", GENBANK, (20041015), Database accession no. AC120144.11, URL: NCBI, XP055176929
		[A] - "Mus musculus chromosome 9, clone RP23-268F15, complete sequence", GENBANK, (20040728), Database accession no. AC113548.22, URL: NCBI, XP055176932
		[A] - "Mus musculus strain C57BL6/J chromosome 17 clone RP23-290119, WORKING DRAFT SEQUENCE", GENBANK, (20020515), Database accession no. AC090975, URL: NCBI, XP055176935
		[A] - FRIEDEL ET AL., "Generating conditional knockout mice.", METHODS MOL BIOL., (2011), vol. 693, pages 205 - 31
	by applicant	US713608
		WO9418313
		WO9509233
		US6824978
		US7135608
		WO2011072246
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