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Extract from the Register of European Patents

EP About this file: EP2917346

EP2917346 - BACTERIAL ENGINEERING [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.04.2019
Database last updated on 20.09.2024
FormerThe patent has been granted
Status updated on  15.05.2018
FormerGrant of patent is intended
Status updated on  27.03.2018
FormerExamination is in progress
Status updated on  09.02.2018
FormerGrant of patent is intended
Status updated on  26.09.2017
FormerExamination is in progress
Status updated on  11.11.2016
Most recent event   Tooltip03.07.2020Lapse of the patent in a contracting state
New state(s): HU, MK		published on 05.08.2020  [2020/32]
Applicant(s)For all designated states
Bactevo Ltd
Merrifield Centre
Rosemary Lane
Cambridge
Cambridgeshire CB1 3LQ / GB
[2018/23]
Former [2015/38]For all designated states
Bactevo Ltd
Merrifield Centre
Rosemary Lane
Cambridge
Cambridgeshire CB1 3LQ / GB
Inventor(s)01 / WILLIAMS, David Hugh
c/o Discuva Limited
260 Science Park
Milton Road
Cambridge Cambridgeshire CB4 0WE / GB
02 / TURNER, Arthur Keith
c/o Discuva Limited
260 Science Park
Milton Road
Cambridge Cambridgeshire CB4 0WE / GB
03 / WAIN, John Richard
c/o Discuva Limited
260 Science Park
Milton Road
Cambridge Cambridgeshire CB4 0WE / GB
 [2015/38]
Representative(s)Hutchins, Michael Richard
Schlich
9 St Catherine's Road
Littlehampton, West Sussex BN17 5HS / GB
[2018/23]
Former [2015/38]EIP
Fairfax House
15 Fulwood Place
London WC1V 6HU / GB
Application number, filing date13811606.605.11.2013
[2015/38]
WO2013GB52893
Priority number, dateGB2012001998906.11.2012         Original published format: GB 201219989
[2015/38]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014072697
Date:15.05.2014
Language:EN
[2014/20]
Type: A1 Application with search report 
No.:EP2917346
Date:16.09.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 15.05.2014 takes the place of the publication of the European patent application.
[2015/38]
Type: B1 Patent specification 
No.:EP2917346
Date:06.06.2018
Language:EN
[2018/23]
Search report(s)International search report - published on:EP15.05.2014
ClassificationIPC:C12N15/10
[2015/38]
CPC:
C12N15/1058 (EP,US); C12N15/102 (EP,US); C12N15/1082 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/38]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:BAKTERIEN-ENGINEERING[2015/38]
English:BACTERIAL ENGINEERING[2015/38]
French:INGÉNIERIE BACTÉRIENNE[2015/38]
Entry into regional phase08.06.2015National basic fee paid 
08.06.2015Designation fee(s) paid 
08.06.2015Examination fee paid 
Examination procedure08.06.2015Examination requested  [2015/38]
02.11.2015Amendment by applicant (claims and/or description)
14.11.2016Despatch of a communication from the examining division (Time limit: M04)
08.12.2016Reply to a communication from the examining division
28.04.2017Despatch of a communication from the examining division (Time limit: M04)
19.06.2017Reply to a communication from the examining division
27.09.2017Communication of intention to grant the patent
07.02.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
28.03.2018Communication of intention to grant the patent
25.04.2018Fee for grant paid
25.04.2018Fee for publishing/printing paid
25.04.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.11.2016
Opposition(s)07.03.2019No opposition filed within time limit [2019/20]
Fees paidRenewal fee
24.11.2015Renewal fee patent year 03
23.11.2016Renewal fee patent year 04
29.11.2017Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU05.11.2013
AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
MK06.06.2018
NL06.06.2018
PL06.06.2018
PT06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
TR06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
IE05.11.2018
LU05.11.2018
MT05.11.2018
BE30.11.2018
[2020/31]
Former [2020/28]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
PT06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
TR06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
IE05.11.2018
LU05.11.2018
MT05.11.2018
BE30.11.2018
Former [2020/16]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
TR06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
IE05.11.2018
LU05.11.2018
MT05.11.2018
BE30.11.2018
Former [2020/08]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
IE05.11.2018
LU05.11.2018
MT05.11.2018
BE30.11.2018
Former [2019/51]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
IE05.11.2018
LU05.11.2018
BE30.11.2018
Former [2019/48]AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
IE05.11.2018
LU05.11.2018
Former [2019/34]AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
LU05.11.2018
Former [2019/33]AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/26]AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/11]AT06.06.2018
CY06.06.2018
CZ06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
IT06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/10]AT06.06.2018
CY06.06.2018
CZ06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
PL06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SK06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/09]CY06.06.2018
EE06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/08]CY06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/03]CY06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
Former [2018/52]CY06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
Former [2018/51]CY06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
Former [2018/50]CY06.06.2018
ES06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
Former [2018/49]CY06.06.2018
ES06.06.2018
FI06.06.2018
LT06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
Former [2018/47]ES06.06.2018
FI06.06.2018
LT06.06.2018
NO06.09.2018
Cited inInternational search[Y]US2009104682  (KIM SUN-CHANG [KR], et al) [Y] 2-10 * the whole document *;
 [XYI]  - GEMMA C LANGRIDGE ET AL, "Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants", vol. 19, no. 12, doi:10.1101/GR.097097.109, ISSN 1088-9051, (20091201), pages 2308 - 2316, GENOME RESEARCH, COLD SPRING HARBOR LABORATORY PRESS, WOODBURY, NY, US, URL: http://genome.cshlp.org/content/19/12/2308, (20091013), XP002682200 [X] 1,11,12,17,18,21-29,31,33,37-43 * Abstract; page 2308, column 2, paragraph l - page 2309, column 1, paragraphs 1,2; table 1 * * page 2310, column 2, paragraph l - page 2312, column 1, paragraph 1; figure 4 * * page 2314, column 1, paragraph l - page 2314, column 2, paragraph 1 * * page 2314, column 2, paragraph l - page 2315, column 2, paragraph 3 * [Y] 2-10,13-16,19,20 [I] 30,32,34-36

DOI:   http://dx.doi.org/10.1101/GR.097097.109
 [Y]  - MAUS C E ET AL, "Mutation of tlyA Confers Capreomycin Resistance in Mycobacterium tuberculosis", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (20050201), vol. 49, no. 2, doi:10.1128/AAC.49.2.571-577.2005, ISSN 0066-4804, pages 571 - 577, XP007901245 [Y] 2-10,13-16,19,20 * abstract; page 572, column 1, paragraph 3; figure 1 * * page 572, column 2, paragraph l - page 573, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1128/AAC.49.2.571-577.2005
 [Y]  - JUN LIN ET AL, "Systematic Identification of Genetic Loci Required for Polymyxin Resistance in Campylobacter jejuni Using an Efficient In Vivo Transposon Mutagenesis System", FOODBORNE PATHOGENS AND DISEASE, MARY ANN LIEBERT, INC. PUBLISHERS, US, vol. 6, no. 2, doi:10.1089/FPD.2008.0177, ISSN 1535-3141, (20090301), pages 173 - 185, (20081223), XP002682201 [Y] 2-10,13-16,19,20 * page 174, column 1, paragraph 2 - page 174, column 2, paragraph 2 * * Abstract; page 175, column 1, paragraph 2 - page 175, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1089/FPD.2008.0177
 [Y]  - HARE R S ET AL, "Genetic footprinting in bacteria", JOURNAL OF BACTERIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC; US, (20010301), vol. 183, no. 5, doi:10.1128/JB.183.5.1694-1706.2001, ISSN 0021-9193, pages 1694 - 1706, XP002243541 [Y] 2-10,13-16,19,20 * Abstract; page 1697, column 1, paragraph 2 - page 1698, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1128/JB.183.5.1694-1706.2001
 [Y]  - TONG X ET AL, "Genome-scale identification of conditionally essential genes in E. coli by DNA microarrays", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (20040910), vol. 322, no. 1, doi:10.1016/J.BBRC.2004.07.110, ISSN 0006-291X, pages 347 - 354, XP004526740 [Y] 2-10,13-16,19,20 * Abstract; page 348, column 1, paragraph 4 - page 348, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2004.07.110
 [Y]  - JIAO YONGQIN ET AL, "Isolation and characterization of a genetically tractable photo autotrophic Fe(II)-oxidizing bacterium, Rhodopseudomonas palustris strain TIE-1", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (200508), vol. 71, no. 8, ISSN 0099-2240, pages 4487 - 4496, XP002720185 [Y] 2-10,13-16,19,20 * Abstract; page 4488, column 1, paragraph 2 * * page 4489, column 1, paragraph 4 * * page 4489, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1128/AEM.71.8.4487-4496.2005
 [Y]  - PUTRINS MARTA ET AL, The impact of ColRS two-component system and TtgABC efflux pump on phenol tolerance of Pseudomonas putida becomes evident only in growing bacteria, BMC MICROBIOLOGY, VOL. 10, PAGE(S) ARTICLE NO.: 110, (201004), ISSN 1471-2180, XP002720186 [Y] 2-10,13-16,19,20 * Abstract; page 2, column 2, paragraph l - page 3, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1186/1471-2180-10-110
 [Y]  - KOMATSU MAMORU ET AL, Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 9 FEB 2010, VOL. 107, NR. 6, PAGE(S) 2646 - 2651, (20100209), ISSN 1091-6490, XP002720187 [Y] 13-16,19,20 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.0914833107
 [A]  - CIAMPI M S ET AL, "TRANSPOSON TN-10 PROVIDES A PROMOTER FOR TRANSCRIPTION OF ADJACENT SEQUENCES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, (19820801), vol. 79, no. 16, ISSN 0027-8424, pages 5016 - 5020, XP002682203 [A] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.79.16.5016
Examination   - S. J. Salipante ET AL, "GeneHunter, a Transposon Tool for Identification and Isolation of Cryptic Antibiotic Resistance Genes", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, (20031201), vol. 47, no. 12, doi:10.1128/AAC.47.12.3840-3845.2003, ISSN 0066-4804, pages 3840 - 3845, XP055270336

DOI:   http://dx.doi.org/10.1128/AAC.47.12.3840-3845.2003
by applicantWO0107651
 WO2008024129
    - KOMATSU ET AL., PNAS, (2010), vol. 107, no. 6, pages 2646 - 2651
    - LANGRIDGE ET AL., GENOME RESEARCH, (2009), vol. 19, pages 2308 - 2316
    - GAWRONSKI ET AL., PNAS, (2009), vol. 106, pages 16422 - 16427
    - GOODMAN ET AL., CELL HOST MICROBE, (2009), vol. 6, pages 279 - 289
    - VAN OPIJNEN ET AL., NAT. METHODS, (2009), vol. 6, pages 767 - 772
    - GALLAGHER ET AL., MBIO, (2011), vol. 2, no. 1, pages E00315 - 10
    - MADYAGOL ET AL., FOLIA MICROBIOL, (2011), vol. 56, pages 253 - 263
    - TROESCHEL ET AL., METHODS MOL BIOL., (2010), vol. 668, pages 117 - 39
    - KIM ET AL., CURR MICROBIOL., (2008), vol. 57, no. 4, pages 391 - 394
    - ALTSCHUL ET AL., J. MOL. BIOL., (1990), vol. 215, pages 403 - 410
    - ALTSCHUL ET AL., NUCL. ACIDS RES., (1997), vol. 25, pages 3389 - 3402
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.