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Extract from the Register of European Patents

EP About this file: EP2872489

EP2872489 - SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  27.10.2017
Database last updated on 26.04.2025
FormerThe patent has been granted
Status updated on  18.11.2016
FormerGrant of patent is intended
Status updated on  14.11.2016
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Siemens Healthcare Diagnostics Inc.
511 Benedict Avenue
Tarrytown, NY 10591 / US
[2015/21]
Inventor(s)01 / MATRAJAN, Anand
77 Madeline Road
Manchester, NH 03104 / US
02 / WEN, David
17 Thoreau Road
Northborough, MA 01532 / US
 [2015/21]
Representative(s)Schweitzer, Klaus, et al
Dr. Müller Patentanwälte
Mühlstraße 9A
65597 Hünfelden / DE
[N/P]
Former [2015/21]Schweitzer, Klaus, et al
Plate Schweitzer Zounek Patentanwälte Rheingaustrasse 196
65203 Wiesbaden / DE
Application number, filing date13817300.010.07.2013
[2016/51]
WO2013US49910
Priority number, dateUS201261670013P10.07.2012         Original published format: US 201261670013 P
[2015/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014011762
Date:16.01.2014
Language:EN
[2014/03]
Type: A1 Application with search report 
No.:EP2872489
Date:20.05.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 16.01.2014 takes the place of the publication of the European patent application.
[2015/21]
Type: B1 Patent specification 
No.:EP2872489
Date:21.12.2016
Language:EN
[2016/51]
Search report(s)International search report - published on:US16.01.2014
(Supplementary) European search report - dispatched on:EP10.11.2015
ClassificationIPC:C07D219/04
[2015/21]
CPC:
C07D219/04 (EP,CN,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/21]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:SYNTHESE VON ACRIDINIUMVERBINDUNGEN DURCH N-ALKYLIERUNG VON ACRIDONEN[2015/21]
English:SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS[2015/21]
French:SYNTHÈSE DE COMPOSÉS D'ACRIDINIUM PAR N-ALKYLATION D'ACRIDANES[2015/21]
Entry into regional phase10.02.2015National basic fee paid 
10.02.2015Search fee paid 
10.02.2015Designation fee(s) paid 
10.02.2015Examination fee paid 
Examination procedure10.02.2015Examination requested  [2015/21]
07.06.2016Amendment by applicant (claims and/or description)
08.07.2016Communication of intention to grant the patent
07.11.2016Fee for grant paid
07.11.2016Fee for publishing/printing paid
07.11.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  08.07.2016
Opposition(s)22.09.2017No opposition filed within time limit [2017/48]
Fees paidRenewal fee
20.07.2015Renewal fee patent year 03
20.07.2016Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU10.07.2013
AL21.12.2016
AT21.12.2016
BE21.12.2016
CY21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
MC21.12.2016
MK21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
TR21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
MT10.07.2017
CH31.07.2017
LI31.07.2017
[2020/34]
Former [2020/15]HU10.07.2013
AT21.12.2016
BE21.12.2016
CY21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
MC21.12.2016
MK21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
TR21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
MT10.07.2017
CH31.07.2017
LI31.07.2017
Former [2019/52]HU10.07.2013
AT21.12.2016
BE21.12.2016
CY21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
MC21.12.2016
MK21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
MT10.07.2017
CH31.07.2017
LI31.07.2017
Former [2019/47]HU10.07.2013
AT21.12.2016
BE21.12.2016
CY21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
MC21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
MT10.07.2017
CH31.07.2017
LI31.07.2017
Former [2019/31]HU10.07.2013
AT21.12.2016
BE21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
MC21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
MT10.07.2017
CH31.07.2017
LI31.07.2017
Former [2019/30]AT21.12.2016
BE21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
MC21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
MT10.07.2017
CH31.07.2017
LI31.07.2017
Former [2018/43]AT21.12.2016
BE21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
MT10.07.2017
CH31.07.2017
LI31.07.2017
Former [2018/34]AT21.12.2016
BE21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
IE10.07.2017
LU10.07.2017
CH31.07.2017
LI31.07.2017
Former [2018/21]AT21.12.2016
BE21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
CH31.07.2017
LI31.07.2017
Former [2018/14]AT21.12.2016
BE21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SI21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
Former [2018/01]AT21.12.2016
BE21.12.2016
CZ21.12.2016
DK21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
Former [2017/41]AT21.12.2016
BE21.12.2016
CZ21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
IT21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SK21.12.2016
SM21.12.2016
BG21.03.2017
NO21.03.2017
GR22.03.2017
IS21.04.2017
PT21.04.2017
Former [2017/36]BE21.12.2016
CZ21.12.2016
EE21.12.2016
FI21.12.2016
HR21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
PL21.12.2016
RO21.12.2016
RS21.12.2016
SE21.12.2016
SK21.12.2016
NO21.03.2017
GR22.03.2017
IS21.04.2017
Former [2017/34]CZ21.12.2016
FI21.12.2016
HR21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
RS21.12.2016
SE21.12.2016
NO21.03.2017
GR22.03.2017
Former [2017/31]FI21.12.2016
HR21.12.2016
LT21.12.2016
LV21.12.2016
NL21.12.2016
RS21.12.2016
SE21.12.2016
NO21.03.2017
GR22.03.2017
Former [2017/28]FI21.12.2016
HR21.12.2016
LT21.12.2016
LV21.12.2016
RS21.12.2016
SE21.12.2016
NO21.03.2017
GR22.03.2017
Former [2017/12]LV21.12.2016
Documents cited:Search[A]  - AUGUST BERNTHSEN, "Die Acridine", JUSTUS LIEBIGS ANNALEN DER CHEMIE, VERLAG CHEMIE GMBH, WEINHEIM; DE, vol. 224, doi:10.1002/JLAC.18842240102, ISSN 0075-4617, (18840101), pages 1 - 56, (20060124), XP009186849 [A] 1-16 * first step: page 16, last paragraph and page 26, third paragraph * * second step: page 27, item 7) * * third step: page 27, last full paragraph *

DOI:   http://dx.doi.org/10.1002/jlac.18842240102
 [A]  - AUGUST BERNTHSEN AND FRITZ BENDER, "Ueber die Bildung von Nitrilbasen aus organischen Säuren und Aminen; Synthese der Acridine", CHEMISCHE BERICHTE, VCH, DE, (18830701), vol. 16, no. 2, ISSN 0009-2940, pages 1802 - 1819, XP009186848 [A] 1-16 * first step: page 1815 * * second step: page 1816 * * third step: page 1817 *
International search[A]US2010256380  (NATRAJAN, A ET AL.);
 [A]US8034636  (EVANGELISTA, R ET AL.);
 [A]US8119422  (NATRAJAN, A ET AL.);
 [A]US5656426  (LAW, SJ ET AL.);
 [A]US7781588  (WANG, H ET AL.);
 [A]GB930963  (CRAIG, PN);
 [A]US6664043  (NATRAJAN, A ET AL.);
 [A]US2008248493  (MATTINGLY, PG ET AL.)
 [A]  - NATRAJAN, A ET AL., "Facile N-alkylation of acridine esters with 1,3-propane sultone in ionic liquids.", GREEN CHEMISTRY, (20110209), vol. 13, pages 913 - 921, XP055185019

DOI:   http://dx.doi.org/10.1039/c0gc00758g
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.