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Extract from the Register of European Patents

EP About this file: EP2885642

EP2885642 - METHODS AND SYSTEMS FOR SCREENING COMPOSITIONS COMPRISING NON-ANTICOAGULANT SULFATED POLYSACCHARIDES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.03.2020
Database last updated on 17.09.2024
FormerThe patent has been granted
Status updated on  12.04.2019
FormerGrant of patent is intended
Status updated on  27.11.2018
FormerExamination is in progress
Status updated on  10.03.2017
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Baxalta GmbH
Zaehlerweg 4
6300 Zug / CH
For all designated states
Baxalta Incorporated
1200 Lakeside Drive
Bannockburn, IL 60015 / US
[2018/31]
Former [2016/01]For all designated states
Baxalta GmbH
Thurgauerstrasse 130
8152 Glattpark, Opfikon / CH
For all designated states
Baxalta Incorporated
1200 Lakeside Drive
Bannockburn, IL 60015 / US
Former [2015/26]For all designated states
Baxter International Inc
One Baxter Parkway
Deerfield, IL 60015 / US
For all designated states
Baxter Healthcare SA
Thurgauerstrasse 130
8152 Glattpark (Opfikon) / CH
Inventor(s)01 / DOCKAL, Michael
Mariahilferstrasse 173-175/2/54
A-1150 Vienna / AT
02 / SCHEIFLINGER, Friedrich
Michelbeuerngasse 4/17
A-1090 Vienna / AT
03 / ZHANG, Zhenqing
Gaohe Road 58
87 -701 Suzhou Industrial Park
Suzhou Jiangsu Province 215021 / CN
04 / TILL, Susanne
Schrotzbergstrasse 2/23
A-1020 Vienna / AT
05 / KNAPPE, Sabine
Magdalenenstrasse 6/8
A-1060 Vienna / AT
06 / SZABO, Christina
37121 N. Twin Oaks Drive
Lake Villa, IL 60046 / US
 [2015/26]
Representative(s)Goodfellow, Hugh Robin
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2019/20]
Former [2015/26]Wilkinson, Stephen John
Stevens, Hewlett & Perkins
1 St. Augustine's Place
Bristol BS1 4UD / GB
Application number, filing date13829280.012.08.2013
[2019/20]
WO2013US54527
Priority number, dateUS201261683144P14.08.2012         Original published format: US 201261683144 P
[2015/26]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014028382
Date:20.02.2014
Language:EN
[2014/08]
Type: A1 Application with search report 
No.:EP2885642
Date:24.06.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 20.02.2014 takes the place of the publication of the European patent application.
[2015/26]
Type: B1 Patent specification 
No.:EP2885642
Date:15.05.2019
Language:EN
[2019/20]
Search report(s)International search report - published on:KR20.02.2014
(Supplementary) European search report - dispatched on:EP15.06.2016
ClassificationIPC:G01N33/86, G01N33/50, G01N33/48
[2015/26]
CPC:
G01N33/86 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/26]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN UND SYSTEME ZUM SCREENING VON ZUSAMMENSETZUNGEN MIT NICHT GERINNENDEN SULFATIERTEN POLYSACCHARIDEN[2015/26]
English:METHODS AND SYSTEMS FOR SCREENING COMPOSITIONS COMPRISING NON-ANTICOAGULANT SULFATED POLYSACCHARIDES[2015/26]
French:PROCÉDÉS ET SYSTÈMES DE CRIBLAGE DE COMPOSITIONS COMPRENANT DES POLYSACCHARIDES SULFATÉS NON COAGULANTS[2015/26]
Entry into regional phase11.02.2015National basic fee paid 
11.02.2015Search fee paid 
11.02.2015Designation fee(s) paid 
11.02.2015Examination fee paid 
Examination procedure11.02.2015Examination requested  [2015/26]
03.01.2017Amendment by applicant (claims and/or description)
08.03.2017Despatch of a communication from the examining division (Time limit: M04)
18.07.2017Reply to a communication from the examining division
08.11.2018Cancellation of oral proceeding that was planned for 16.11.2018
16.11.2018Date of oral proceedings (cancelled)
28.11.2018Communication of intention to grant the patent
02.04.2019Fee for grant paid
02.04.2019Fee for publishing/printing paid
02.04.2019Receipt of the translation of the claim(s)
Divisional application(s)EP19174514.0  / EP3594686
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  08.03.2017
Opposition(s)18.02.2020No opposition filed within time limit [2020/17]
Fees paidRenewal fee
27.08.2015Renewal fee patent year 03
29.08.2016Renewal fee patent year 04
27.09.2017Renewal fee patent year 05
23.08.2018Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.08.201705   M06   Fee paid on   27.09.2017
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU12.08.2013
AL15.05.2019
CY15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
MC15.05.2019
MK15.05.2019
MT15.05.2019
PL15.05.2019
RO15.05.2019
RS15.05.2019
SI15.05.2019
SK15.05.2019
SM15.05.2019
TR15.05.2019
LU12.08.2019
BG15.08.2019
GR16.08.2019
IS15.09.2019
PT15.09.2019
[2022/31]
Former [2021/34]HU12.08.2013
AL15.05.2019
CY15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
MC15.05.2019
MT15.05.2019
PL15.05.2019
RO15.05.2019
RS15.05.2019
SI15.05.2019
SK15.05.2019
SM15.05.2019
TR15.05.2019
LU12.08.2019
BG15.08.2019
GR16.08.2019
IS15.09.2019
PT15.09.2019
Former [2021/32]HU12.08.2013
AL15.05.2019
CY15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
MC15.05.2019
PL15.05.2019
RO15.05.2019
RS15.05.2019
SI15.05.2019
SK15.05.2019
SM15.05.2019
TR15.05.2019
LU12.08.2019
BG15.08.2019
GR16.08.2019
IS15.09.2019
PT15.09.2019
Former [2021/31]AL15.05.2019
CY15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
MC15.05.2019
PL15.05.2019
RO15.05.2019
RS15.05.2019
SI15.05.2019
SK15.05.2019
SM15.05.2019
TR15.05.2019
LU12.08.2019
BG15.08.2019
GR16.08.2019
IS15.09.2019
PT15.09.2019
Former [2021/26]AL15.05.2019
CY15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
MC15.05.2019
PL15.05.2019
RO15.05.2019
RS15.05.2019
SI15.05.2019
SK15.05.2019
SM15.05.2019
TR15.05.2019
LU12.08.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2020/25]AL15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
MC15.05.2019
PL15.05.2019
RO15.05.2019
RS15.05.2019
SI15.05.2019
SK15.05.2019
SM15.05.2019
TR15.05.2019
LU12.08.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2020/17]AL15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
RO15.05.2019
RS15.05.2019
SK15.05.2019
SM15.05.2019
TR15.05.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2020/14]AL15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
RO15.05.2019
RS15.05.2019
SK15.05.2019
SM15.05.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2020/11]AL15.05.2019
CZ15.05.2019
EE15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
RO15.05.2019
RS15.05.2019
SK15.05.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2020/10]AL15.05.2019
CZ15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
RO15.05.2019
RS15.05.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2020/09]AL15.05.2019
CZ15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
RS15.05.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2019/51]AL15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
RS15.05.2019
BG15.08.2019
GR16.08.2019
PT15.09.2019
Former [2019/50]AL15.05.2019
HR15.05.2019
LT15.05.2019
LV15.05.2019
RS15.05.2019
GR16.08.2019
PT15.09.2019
Former [2019/48]LT15.05.2019
PT15.09.2019
Former [2019/47]LT15.05.2019
Documents cited:Search[X]WO2005117912  (AVIGEN INC [US], et al) [X] 1-10 * claims, example 3; par.158, 161 *;
 [X]WO2008103234  (AVIGEN INC [US], et al) [X] 1-10 * p.10 par.2, example 3 p.22, example 4 p.31, conclusion p.33; claims *;
 [X]WO2011088267  (BAXTER INT [US], et al) [X] 1-10 * examples 4-7; claims; p.1 l.28 - p.3 l.29 *
 [T]  - ZHANG ZHENQING ET AL, "Screening of complex fucoidans from four brown algae species as procoagulant agents", CARBOHYDRATE POLYMERS, APPLIED SCIENCE PUBLISHERS, LTD. BARKING, GB, (20140907), vol. 115, doi:10.1016/J.CARBPOL.2014.09.001, ISSN 0144-8617, pages 677 - 685, XP029019640

DOI:   http://dx.doi.org/10.1016/j.carbpol.2014.09.001
 [X]  - ZHANG ZHENQING ET AL, "Screening of Complex-Fucoidans from Different Species of Brown Algae as Procoagulant Drug Candidates Based on Their Activity, Structural Properties, Impurities", GLYCOBIOLOGY, OXFORD UNIVERSITY PRESS, US, (20111101), vol. 21, no. 11, ISSN 0959-6658, page 1508, XP009188156 [X] 1-10 * abstract *
 [X]  - DOCKAL MICHAEL ET AL, "Structural and Functional Characterization of Fucoidan and Its Procoagulant Effect in An Ex Vivo Model of Factor VIII-Inhibited Guinea Pigs", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (201111), Database accession no. PREV201200219543, XP009188172 [X] 1-10 * abstract *
 [X]  - DOCKAL MICHAEL ET AL, "Anticoagulant Activity and Mechanism of Non-Anticoagulant Sulfated Polysaccharides", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (201111), Database accession no. PREV201200218491, XP009188173 [X] 1-10 * abstract *
International search[A]US2009269325  (JOHNSON KIRK W [US]);
 [X]  - LIU, TONGYAO ET AL., "Improved coagulation in bleeding disorders by non-anticoagulant sulfated polysaccharides (NASP)", THROMBOSIS AND HAEMOSTASIS, (2006), vol. 95, no. 1, pages 68 - 76, XP009128550
 [A]  - SCHAUB, ROBERT G., "Recent advances in the development of coagulation factors and procoagulants for the treatment of hemophilia", BIOCHEMICAL PHARMACOLOGY, (2011), vol. 82, no. 2, pages 91 - 98, XP055186706

DOI:   http://dx.doi.org/10.1016/j.bcp.2011.03.015
 [A]  - PIPE, STEVEN W., "Hemophilia: new protein therapeutics", HEMATOLOGY, (2010), vol. 2010, no. 1, pages 203 - 209, XP055186707

DOI:   http://dx.doi.org/10.1182/asheducation-2010.1.203
 [A]  - FOGARTY, PATRICK F., "Biological rationale for new drugs in the bleeding disorders pipeline", HEMATOLOGY, (2011), vol. 2011, no. 1, pages 397 - 404, XP055186710

DOI:   http://dx.doi.org/10.1182/asheducation-2011.1.397
by applicantWO2005117912
 WO2008103234
 WO2011088267
    - ZHANG et al., Glycobiology, (20110000), vol. 21, no. 11, page 1508
    - Biosis, Database accession no. PREV201200219543, XP009188172
    - Dockal Michael; et al.,, "Structural and Functional Characterization of Fucoidan and Its Procoagulant Effect in An Ex Vivo Model of Factor VIII-Inhibited Guinea Pigs", BLOOD,, vol. 118, no. 21, (20111101), page 983, XP009188172
    - Biosis, Database accession no. PREV201200218491, XP009188173
    - Dockal Michael; Till Susanne; Knappe Sabine; Ehrlich Hartmut J; Scheiflinger Friedrich, "Anticoagulant Activity and Mechanism of Non-Anticoagulant Sulfated Polysaccharides", BLOOD,, vol. 118, no. 21, (20111101), page 543, XP009188173
    - CALVO-ASIN, J.A. et al., J. Chem. Soc, Perkin Trans, (19970000), vol. 1, page 1079
    - HEMKER et al., Pathophysiol. Haemost. Thromb., vol. 33, pages 4 - 15
    - LIU et al., Thromb. Haemost., vol. 95, pages 68 - 76
    - NORDFANG et al., Thromb Haemost, (19910000), vol. 66, pages 464 - 467
    - WELSCH et al., Thrombosis Research, (19910000), vol. 64, pages 213 - 222
 US20100449712
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