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Extract from the Register of European Patents

EP About this file: EP2884965

EP2884965 - INTERNAL STRUCTURED SELF ASSEMBLING LIPOSOMES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.06.2019
Database last updated on 02.09.2024
FormerThe patent has been granted
Status updated on  06.07.2018
FormerGrant of patent is intended
Status updated on  27.02.2018
Most recent event   Tooltip03.07.2020Lapse of the patent in a contracting state
New state(s): CY, MK
published on 05.08.2020  [2020/32]
Applicant(s)For all designated states
Froese, Aaron
11 Tom Street
Hamilton, Ontario L8R 1X2 / CA
[2015/26]
Inventor(s)01 / see applicant
...
 [2015/26]
Representative(s)Patentanwälte Olbricht Buchhold Keulertz
Partnerschaft mbB
Neue Mainzer Straße 75
60311 Frankfurt am Main / DE
[N/P]
Former [2018/32]Patentanwälte Olbricht Buchhold Keulertz
Partnerschaft mbB
Bettinastraße 53-55
60325 Frankfurt am Main / DE
Former [2015/26]Patentanwälte Olbricht Buchhold Keulertz
Partnerschaft mbB
Bettinastrasse 53-55
60325 Frankfurt / DE
Application number, filing date13829520.914.08.2013
[2018/32]
WO2013CA50622
Priority number, dateUS201261682897P14.08.2012         Original published format: US 201261682897 P
[2015/26]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014026284
Date:20.02.2014
Language:EN
[2014/08]
Type: A1 Application with search report 
No.:EP2884965
Date:24.06.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 20.02.2014 takes the place of the publication of the European patent application.
[2015/26]
Type: B1 Patent specification 
No.:EP2884965
Date:08.08.2018
Language:EN
[2018/32]
Search report(s)International search report - published on:CA20.02.2014
(Supplementary) European search report - dispatched on:EP23.03.2016
ClassificationIPC:A61K9/127, A61K47/24, A61K31/7088
[2015/26]
CPC:
A61K9/127 (EP,US); A61K9/1272 (US); A61K31/7105 (EP,US);
A61K31/713 (EP,US); A61K47/26 (US); A61K9/1274 (US);
A61K9/1277 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/26]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:STRUKTURIERTE INTERNER SELBSTANORDNENDE LIPOSOME[2015/26]
English:INTERNAL STRUCTURED SELF ASSEMBLING LIPOSOMES[2015/26]
French:LIPOSOMES À AUTO-ASSEMBLAGE ET STRUCTURE INTERNE[2015/26]
Entry into regional phase11.03.2015National basic fee paid 
11.03.2015Search fee paid 
11.03.2015Designation fee(s) paid 
11.03.2015Examination fee paid 
Examination procedure11.03.2015Amendment by applicant (claims and/or description)
11.03.2015Examination requested  [2015/26]
12.04.2016Despatch of a communication from the examining division (Time limit: M04)
19.08.2016Reply to a communication from the examining division
28.02.2018Communication of intention to grant the patent
19.06.2018Receipt of the translation of the claim(s)
28.06.2018Fee for grant paid
28.06.2018Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.04.2016
Opposition(s)09.05.2019No opposition filed within time limit [2019/29]
Fees paidRenewal fee
31.08.2015Renewal fee patent year 03
31.08.2016Renewal fee patent year 04
30.08.2017Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU14.08.2013
AL08.08.2018
AT08.08.2018
CY08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
MK08.08.2018
NL08.08.2018
PL08.08.2018
PT08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SI08.08.2018
SK08.08.2018
SM08.08.2018
TR08.08.2018
IE14.08.2018
LU14.08.2018
MT14.08.2018
BE31.08.2018
CH31.08.2018
LI31.08.2018
FR08.10.2018
BG08.11.2018
GB08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
[2020/31]
Former [2020/28]HU14.08.2013
AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
PT08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SI08.08.2018
SK08.08.2018
SM08.08.2018
TR08.08.2018
IE14.08.2018
LU14.08.2018
MT14.08.2018
BE31.08.2018
CH31.08.2018
LI31.08.2018
FR08.10.2018
BG08.11.2018
GB08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2020/16]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SI08.08.2018
SK08.08.2018
SM08.08.2018
TR08.08.2018
IE14.08.2018
LU14.08.2018
MT14.08.2018
BE31.08.2018
CH31.08.2018
LI31.08.2018
FR08.10.2018
BG08.11.2018
GB08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2020/08]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SI08.08.2018
SK08.08.2018
SM08.08.2018
IE14.08.2018
LU14.08.2018
MT14.08.2018
BE31.08.2018
CH31.08.2018
LI31.08.2018
FR08.10.2018
BG08.11.2018
GB08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2020/03]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SI08.08.2018
SK08.08.2018
SM08.08.2018
IE14.08.2018
LU14.08.2018
BE31.08.2018
CH31.08.2018
LI31.08.2018
FR08.10.2018
BG08.11.2018
GB08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/38]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SI08.08.2018
SK08.08.2018
SM08.08.2018
IE14.08.2018
LU14.08.2018
BE31.08.2018
CH31.08.2018
LI31.08.2018
FR08.10.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/37]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SI08.08.2018
SK08.08.2018
SM08.08.2018
IE14.08.2018
LU14.08.2018
CH31.08.2018
LI31.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/33]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SK08.08.2018
SM08.08.2018
IE14.08.2018
LU14.08.2018
CH31.08.2018
LI31.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/28]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
MC08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SK08.08.2018
SM08.08.2018
LU14.08.2018
CH31.08.2018
LI31.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/26]AL08.08.2018
AT08.08.2018
CZ08.08.2018
DK08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SK08.08.2018
SM08.08.2018
LU14.08.2018
CH31.08.2018
LI31.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/23]AL08.08.2018
AT08.08.2018
CZ08.08.2018
EE08.08.2018
ES08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
SK08.08.2018
LU14.08.2018
CH31.08.2018
LI31.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/22]AL08.08.2018
AT08.08.2018
CZ08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
NL08.08.2018
PL08.08.2018
RO08.08.2018
RS08.08.2018
SE08.08.2018
LU14.08.2018
CH31.08.2018
LI31.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/21]AL08.08.2018
AT08.08.2018
FI08.08.2018
HR08.08.2018
IT08.08.2018
LT08.08.2018
LV08.08.2018
NL08.08.2018
PL08.08.2018
RS08.08.2018
SE08.08.2018
LU14.08.2018
CH31.08.2018
LI31.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/12]AL08.08.2018
AT08.08.2018
FI08.08.2018
HR08.08.2018
LT08.08.2018
LV08.08.2018
NL08.08.2018
PL08.08.2018
RS08.08.2018
SE08.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/11]AT08.08.2018
FI08.08.2018
HR08.08.2018
LT08.08.2018
NL08.08.2018
PL08.08.2018
RS08.08.2018
SE08.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/10]AT08.08.2018
FI08.08.2018
LT08.08.2018
NL08.08.2018
PL08.08.2018
RS08.08.2018
SE08.08.2018
BG08.11.2018
NO08.11.2018
GR09.11.2018
IS08.12.2018
Former [2019/09]FI08.08.2018
LT08.08.2018
NL08.08.2018
NO08.11.2018
IS08.12.2018
Former [2019/08]FI08.08.2018
LT08.08.2018
NO08.11.2018
IS08.12.2018
Former [2019/07]LT08.08.2018
Documents cited:Search[XY]WO0149265  (DANA FARBER CANCER INST INC [US]) [X] 1-3,5,9-16 * the whole document * * pages 19-22; figure 11; example -; claim - * [Y] 1-16;
 [XY]  - QASIM SALEEM ET AL, "Lipogels: Single-Lipid-Bilayer-Enclosed Hydrogel Spheres", BIOMACROMOLECULES, US, (20110613), vol. 12, no. 6, doi:10.1021/bm200266z, ISSN 1525-7797, pages 2364 - 2374, XP055256380 [X] 1,5,9,12-16 * the whole document * * page 2365; tables 1,2 * [Y] 1-16

DOI:   http://dx.doi.org/10.1021/bm200266z
 [XY]  - CHARLENE C. NG ET AL, "Properties of a Self-Assembled Phospholipid Membrane Supported on Lipobeads", BIOPHYSICAL JOURNAL, US, (20040701), vol. 87, no. 1, doi:10.1529/biophysj.103.030627, ISSN 0006-3495, pages 323 - 331, XP055248565 [X] 1,5 * the whole document * [Y] 1-16

DOI:   http://dx.doi.org/10.1529/biophysj.103.030627
 [Y]  - K. KHOSRAVI-DARANI ET AL, "Nanoliposome Potentials in Nanotherapy: A Concise Overview", INT. J. NANOSCI. NANOTECHNOL., (20100331), vol. 6, no. 1, pages 3 - 13, XP055256293 [Y] 1-16 * the whole document *
 [Y]  - NEIL MACKINNON ET AL, "Triggered Instability of Liposomes Bound to Hydrophobically Modified Core-Shell PNIPAM Hydrogel Beads", LANGMUIR, NEW YORK, NY; US, (20100119), vol. 26, no. 2, doi:10.1021/la902423v, ISSN 0743-7463, pages 1081 - 1089, XP055256386 [Y] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1021/la902423v
 [T]  - YASAMAN DAYANI ET AL, "Liposomes with Double-Stranded DNA Anchoring the Bilayer to a Hydrogel Core", BIOMACROMOLECULES, US, (20130101), vol. 14, no. 10, doi:10.1021/bm401155a, ISSN 1525-7797, pages 3380 - 3385, XP055248578 [T] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1021/bm401155a
International search[A]WO9221329  (A & S BIOVECTEURS [FR]);
 [X]WO0149265  (DANA FARBER CANCER INST INC [US]);
 [A]CA2567741  (CHIMERACORE INC [US]);
 [A]CA2793604  (MASSACHUSETTS INST TECHNOLOGY [US]);
 [A]  - NG ET AL., "Properties of a self-assembled phospholipid membrane supported on lipobeads", BIOPHYSICAL JOURNAL, vol. 87, pages 323 - 331, XP055248565

DOI:   http://dx.doi.org/10.1529/biophysj.103.030627
 [A]  - BUCK ET AL., "Engineering lipobeads: Properties of the hydrogel core and the lipid bilayer shell", BIOMACROMOLECULES, (2004), vol. 5, pages 2230 - 2237, XP055248567

DOI:   http://dx.doi.org/10.1021/bm049751+
 [A]  - GUTMAYER ET AL., "Synthesis of a polymer skeleton at the inner leaflet of liposomal membranes: Polymerization of membrane-adsorbed pH-sensitive monomers", BIOMACROMOLECULES, (2006), vol. 7, pages 1422 - 1428, XP055248570

DOI:   http://dx.doi.org/10.1021/bm0580126
 [A]  - STAUCH ET AL., "Mimicking a cytoskeleton by coupling Poly(N-isopropylacrylamide) to the inner leaflet of liposomal membranes: Effects of photopolymerization on vesicle shape and polymer architecture", BIOMACROMOLECULES, (2002), vol. 3, pages 324 - 332, XP002673756

DOI:   http://dx.doi.org/10.1021/BM015613Y
 [T]  - DAYANI ET AL., "Liposomes with double-stranded DNA anchoring the bilayer to a hydrogel core", BIOMACROMOLECULES, (2013), vol. 14, pages 3380 - 3385, XP055248578

DOI:   http://dx.doi.org/10.1021/bm401155a
by applicant   - KHOSRAVI-DARANI K.; MOZAFARI M. R., "Nanoliposome Potentials in Nanotherapy: A Concise Overview", INT. J. NANOSCI. NANOTECHNOL., (2010), vol. 6, no. 1, pages 3 - 13, XP055256293
    - MACKINNON N. ET AL., "Triggered Instability of Liposomes Bound to Hydrophobically Modified Core-Shell PMIPAM Hydrogel Beads", LANGMUIR, (2010), vol. 26, no. 2, doi:doi:10.1021/la902423v, pages 1081 - 89, XP055256386

DOI:   http://dx.doi.org/10.1021/la902423v
    - DAYANI Y.; MALMSTADT N., "Liposomes with Double-Stranded DNA Anchoring the Bilayer to a Hydrogel Core", BIOMAC, (2013), vol. 14, pages 3370 - 85
    - VARMA, M.V.; KHANDAVILLI, S.; ASHOKRAJ, Y.; JAIN, A.; DHANIKULA, A.; SOOD, A.; THOMAS, N.S; PILLAI, O.; SHARMA, P.; GANDHI, R. ET, "Biopharmaceutic classification system: a scientific framework for pharmacokinetic optimization in drug research", CURR. DRUG METAB., (2004), vol. 5, pages 375 - 388
    - SHAW, J.P.; KENT, K.; BIRD, J.; FISHBACK, J.; FROEHLER, B., "Modified deoxyoligonucleotides stable to exonuclease degradation in serum", NUCLEIC ACIDS RES., (1991), vol. 19, pages 747 - 750
    - XU, L.; ANCHORDOQUY, T., "Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics", J. PHARM. SCI., (2011), vol. 100, doi:doi:10.1002/jps.22243, pages 38 - 52, XP055044014

DOI:   http://dx.doi.org/10.1002/jps.22243
    - KRINGELUM, J.V.; NIELSEN, M.; PADKJAER, S.B.; LUND, O., "Structural analysis of B-cell epitopes in antibody:protein complexes", MOL. IMMUNOL., (2012), vol. 53, pages 24 - 34
    - KASPER, C.K., "Complications of hemophilia A treatment:factor VIII inhibitors", ANN N Y ACAD SCI., (1991), vol. 614, pages 97 - 105
    - TANI, J.; FAUSTINE; SUFIAN, J.T., "Updates on current advances in gene therapy", WEST INDIAN MED. J., (2011), vol. 60, pages 188 - 194
    - GRIEGER, J.C.; SAMULSKI, R.J., "Adeno-associated virus vectorology, manufacturing, and clinical applications", METHODS ENZYMOL., (2012), vol. 507, pages 229 - 254
    - JACOBS, F.; WANG, L., "Adeno-associated viral vectors for correction of inborn errors of metabolism: progressing towards clinical application", CURR. PHARM. DES., (2011), vol. 17, doi:doi:10.2174/138161211797247569, pages 2500 - 2515, XP055017907

DOI:   http://dx.doi.org/10.2174/138161211797247569
    - PEER, D.; MARGALIT, R., "Physicochemical evaluation of a stability-driven approach to drug entrapment in regular and in surface-modified liposomes", ARCH. BIOCHEM. BIOPHYS, (2000), vol. 383, pages 185 - 190
    - PEER, D.; KARP, J.M.; HONG, S.; FAROKHZAD, O.C.; MARGALIT, R.; LANGER, R., "Nanocarriers as an emerging platform for cancer therapy", NAT. NANOTECHNOL, (2007), vol. 2, doi:doi:10.1038/nnano.2007.387, pages 751 - 760, XP002531251

DOI:   http://dx.doi.org/10.1038/nnano.2007.387
    - GUO, X.; HUANG, L., "Recent advances in nonviral vectors for gene delivery", ACC. CHEM. RES., (2012), vol. 45, pages 971 - 979
    - CABRINI, G.; BEZZERRI, V.; MANCINI, I.; NICOLIS, E.; DECHECCHI, M.C.; TAMANINI, A.; LAMPRONTI, I.; PICCAGLI, L.; BIANCHI, N.; BORG, "Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: decoy oligonucleotides and low-molecular weight compounds", CURR. MED. CHEM., (2010), vol. 17, pages 4392 - 4404
    - TOP, D.; ANTUENO, R.; SALSMAN, J.; CORCORAN, J.; MADER, J.; HOSKIN, D.; TOUHAMI, A.; JERICHO, M.H.; DUNCAN, R., "Liposome reconstitution of a minimal protein-mediated membrane fusion machine", EMBO J., (2005), vol. 24, pages 2980 - 2988
    - BARRY, C.; KEY, T.; HADDAD, R.; DUNCAN, R., "Features of a spatially constrained cystine loop in the p10 FAST protein ectodomain define a new class of viral fusion peptides", J. BIOL. CHEM., (2010), vol. 285, pages 16424 - 16433
    - PEER, D.; FLORENTIN, A.; MARGALIT, R., "Hyaluronan is a key component in cryoprotection and formulation of targeted unilamellar liposomes", BIOCHIM. BIOPHYS. ACTA, (2003), vol. 1612, doi:doi:10.1016/S0005-2736(03)00106-8, pages 76 - 82, XP004422676

DOI:   http://dx.doi.org/10.1016/S0005-2736(03)00106-8
    - ROTHEMUND, P.W., "Folding DNA to create nanoscale shapes and patterns", NATURE, (2006), vol. 440, pages 297 - 302
    - DUTSE, S.W.; YUSOF, N.A., "Microfluidics-based lab-on-chip systems in DNA-based biosensing: an overview", SENSORS (BASEL), (2011), vol. 11, pages 5754 - 5768
    - WALSH, A.S.; YIN, H.; ERBEN, C.M.; WOOD, M.J.; TURBERFIELD, A.J., "DNA cage delivery to mammalian cells", ACS NANO, (2011), vol. 5, pages 5427 - 5432
    - SUN, P.; TROPEA, J.E.; WAUGH, D.S., "Enhancing the solubility of recombinant proteins in Escherichia coli by using hexahistidine-tagged maltose-binding protein as a fusion partner", METHODS MOL. BIOL., (2011), vol. 705, pages 259 - 274
    - BUMB, A.; BRECHBIEL, M.W.; CHOYKE, P.L.; FUGGER, L.; EGGEMAN, A.; PRABHAKARAN, D.; HUTCHINSON, J.; DOBSON, P.J., "Synthesis and characterization of ultra-small superparamagnetic iron oxide nanoparticles thinly coated with silica", NANOTECHNOLOGY, (2008), vol. 19, doi:doi:10.1088/0957-4484/19/33/335601, page 335601, XP020144474

DOI:   http://dx.doi.org/10.1088/0957-4484/19/33/335601
    - FERRARI, E.; DARIOS, F.; ZHANG, F.; NIRANJAN, D.; BAILES, J.; SOLOVIEV, M.; DAVLETOV, B., "Binary polypeptide system for permanent and oriented protein immobilization", J. NANOBIOTECHNOLOGY, (2010), vol. 8, no. 9
    - BISWAS, S.; DODWADKAR, N.S.; SAWANT, R.R.; TORCHILIN, V.P., "Development of the novel PEG-PE-based polymer for the reversible attachment of specific ligands to liposomes: synthesis and in vitro characterization", BIOCONJUG. CHEM., (2011), vol. 22, pages 2005 - 2013
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