blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2890787

EP2890787 - CROWDING AGENT-INDUCED NUCLEIC ACID TRANSFER INTO A RECIPIENT HOST CELL [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.03.2020
Database last updated on 25.09.2024
FormerThe patent has been granted
Status updated on  29.03.2019
FormerGrant of patent is intended
Status updated on  05.12.2018
FormerExamination is in progress
Status updated on  10.11.2017
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Synthetic Genomics, Inc.
11149 N. Torrey Pines Rd, Suite 100
La Jolla, CA 92037 / US
[2015/28]
Inventor(s)01 / KARAS, Bogumil, J.
4605 Olney Street, Apt. 11
San Diego, CA 92109 / US
02 / HUTCHISON, Clyde, A.
5528 Linda Rosa Avenue
La Jolla, CA 92037 / US
03 / SMITH, Hamilton, O.
5345 Toscana Way
Apt 5410
San Diego, CA 92122 / US
04 / SUZUKI, Yo
8799 Gilman Drive, Unit C
La Jolla, CA 92037 / US
 [2015/28]
Representative(s)Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[2019/18]
Former [2015/28]Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP
20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date13833688.830.08.2013
[2019/18]
WO2013US57533
Priority number, dateUS201261695864P31.08.2012         Original published format: US 201261695864 P
[2015/28]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2014036404
Date:06.03.2014
Language:EN
[2014/10]
Type: A2 Application without search report 
No.:EP2890787
Date:08.07.2015
Language:EN
The application published by WIPO in one of the EPO official languages on 06.03.2014 takes the place of the publication of the European patent application.
[2015/28]
Type: B1 Patent specification 
No.:EP2890787
Date:01.05.2019
Language:EN
[2019/18]
Search report(s)International search report - published on:US30.07.2015
(Supplementary) European search report - dispatched on:EP01.06.2016
ClassificationIPC:C12N15/87, C12N15/81
[2018/48]
CPC:
C12N15/87 (EP,US); C12N15/81 (US)
Former IPC [2015/28]C12N15/04
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/28]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:CROWDING-AGENT-INDUZIERTER NUKLEINSÄURETRANSFER IN EINE EMPFÄNGERWIRTSZELLE[2015/28]
English:CROWDING AGENT-INDUCED NUCLEIC ACID TRANSFER INTO A RECIPIENT HOST CELL[2015/28]
French:TRANSFERT D'ACIDE NUCLÉIQUE INDUIT PAR UN AGENT DE RASSEMBLEMENT DANS UNE CELLULE HÔTE RECEVEUSE[2015/28]
Entry into regional phase30.03.2015National basic fee paid 
30.03.2015Search fee paid 
30.03.2015Designation fee(s) paid 
30.03.2015Examination fee paid 
Examination procedure30.03.2015Examination requested  [2015/28]
08.12.2016Amendment by applicant (claims and/or description)
13.11.2017Despatch of a communication from the examining division (Time limit: M04)
21.03.2018Reply to a communication from the examining division
18.07.2018Despatch of a communication from the examining division (Time limit: M02)
10.09.2018Reply to a communication from the examining division
06.12.2018Communication of intention to grant the patent
20.03.2019Fee for grant paid
20.03.2019Fee for publishing/printing paid
20.03.2019Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  13.11.2017
Opposition(s)04.02.2020No opposition filed within time limit [2020/15]
Fees paidRenewal fee
27.08.2015Renewal fee patent year 03
29.08.2016Renewal fee patent year 04
28.08.2017Renewal fee patent year 05
27.08.2018Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.08.2013
AL01.05.2019
AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
MK01.05.2019
MT01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IE30.08.2019
LU30.08.2019
IS01.09.2019
PT01.09.2019
[2022/31]
Former [2021/34]HU30.08.2013
AL01.05.2019
AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
MT01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IE30.08.2019
LU30.08.2019
IS01.09.2019
PT01.09.2019
Former [2021/32]HU30.08.2013
AL01.05.2019
AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IE30.08.2019
LU30.08.2019
IS01.09.2019
PT01.09.2019
Former [2021/26]AL01.05.2019
AT01.05.2019
CY01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IE30.08.2019
LU30.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/36]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IE30.08.2019
LU30.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/25]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
MC01.05.2019
NL01.05.2019
PL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SI01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
LU30.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/17]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
SM01.05.2019
TR01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/14]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
SM01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/12]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
IT01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/11]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
EE01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
SK01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/10]AL01.05.2019
AT01.05.2019
CZ01.05.2019
DK01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RO01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/09]AL01.05.2019
CZ01.05.2019
DK01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2020/04]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
IS01.09.2019
PT01.09.2019
Former [2019/51]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
BG01.08.2019
NO01.08.2019
GR02.08.2019
PT01.09.2019
Former [2019/50]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
LV01.05.2019
NL01.05.2019
RS01.05.2019
SE01.05.2019
NO01.08.2019
GR02.08.2019
PT01.09.2019
Former [2019/49]AL01.05.2019
ES01.05.2019
FI01.05.2019
HR01.05.2019
LT01.05.2019
NL01.05.2019
SE01.05.2019
NO01.08.2019
PT01.09.2019
Former [2019/48]ES01.05.2019
FI01.05.2019
LT01.05.2019
SE01.05.2019
NO01.08.2019
PT01.09.2019
Former [2019/47]ES01.05.2019
FI01.05.2019
LT01.05.2019
NO01.08.2019
Documents cited:Search[X]JP3932307B  (GUNMA PREFECTURE) [X] 1,3,5,8,10,11,14,15 * paragraph [0020] *;
 [I]WO2008144192  (SYNTHETIC GENOMICS INC [US], et al) [I] 1-4,7,11,14,15 * paragraph [0067]; table S4 *;
 [X]WO2009048885  (SYNTHETIC GENOMICS INC [US], et al) [X] 14 * paragraph [0104] - paragraph [0105]; figure 7; examples 1,2 *;
 [X]WO2011109031  (SYNTHETIC GENOMICS INC [US], et al) [X] 14 * abstract * * paragraphs [0290] , [0294] , [0388]; figure 8; example 3A; claim - *;
 [I]  - A. SVOBODA, "Fusion of Yeast Protoplasts Induced by Polyethylene Glycol", JOURNAL OF GENERAL MICROBIOLOGY, GB, (19781101), vol. 109, no. 1, doi:10.1099/00221287-109-1-169, ISSN 0022-1287, pages 169 - 175, XP055271758 [I] 1,5,8,10-12,14,15 * page 172, paragraph l *

DOI:   http://dx.doi.org/10.1099/00221287-109-1-169
 [X]  - VAN SOLINGEN P ET AL, "Fusion of yeast spheroplasts.", JOURNAL OF BACTERIOLOGY MAY 1977, (197705), vol. 130, no. 2, ISSN 0021-9193, pages 946 - 947, XP002757585 [X] 14 * page 946, column 2, line 8 - line 13 *
 [XP]  - BOGUMIL J KARAS ET AL, "Direct transfer of whole genomes from bacteria to yeast", NATURE METHODS, (20130331), vol. 10, no. 5, doi:10.1038/nmeth.2433, ISSN 1548-7091, pages 410 - 412, XP055089021 [XP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/nmeth.2433
 [T]  - KARAS BOGUMIL J ET AL, "Transferring whole genomes from bacteria to yeast spheroplasts using entire bacterial cells to reduce DNA shearing.", NATURE PROTOCOLS APR 2014, (201404), vol. 9, no. 4, ISSN 1750-2799, pages 743 - 750, XP002757586 [T] * the whole document *

DOI:   http://dx.doi.org/10.1038/nprot.2014.045
International search[Y]WO9831837  (MAXYGEN INC [US], et al);
 [Y]WO2004046330  (MORPHOTEK INC [US], et al);
 [Y]  - GURI, A., "Somatic Hybridization Between Selected Lycopersicon And Solanum Species.", PLANT CELL REPORTS., (199106), vol. 10, no. 2, pages 76 - 80, XP055260417

DOI:   http://dx.doi.org/10.1007/BF00236461
 [Y]  - DOGANLAR, S ET AL., "A Comparative Genetic Linkage Map Of Eggplant (Solanum melangena) And Its Implications For Genome Evolution In The Solanaceae.", GENETICS., (200208), vol. 161, pages 1697 - 1711, XP055214124
 [Y]  - KAHN, K. ET AL., "GENE TRANSFER TECHNOLOGIES AND THEIR APPLICATIONS: ROLES IN HUMAN DISEASES.", ASIAN JOURNAL OF EXPERIMENTAL BIOLOGICAL SCIENCES., (2010), vol. 1, no. 1, pages 208 - 218, XP055260423
 [Y]  - BENDERS, G., "Cloning Whole Bacterial Genomes In Yeast.", NUCLEIC ACIDS RESEARCH, (20100307), vol. 38, pages 2558 - 2569, XP002584298

DOI:   http://dx.doi.org/10.1093/NAR/GKQ119
 [Y]  - LARTIGUE, C., "Creating Bacterial Strains From Genomes That Have Been Cloned And Engineered In Yeast.", SCIENCE, (20090925), vol. 325, no. 5948, pages 1693 - 1696, XP002584297

DOI:   http://dx.doi.org/10.1126/SCIENCE.1173759
by applicantWO02057437
 US6670154
 US2005003511
 US2005019924
 US7083971
 WO2008144192
 WO2011109031
    - ITAYA et al., Nat Methods, (20080000), vol. 5, page 41
    - YOON; KOOB, Nucleic Acids Res, (20030000), vol. 31, page 1407
    - WHEELER et al., Gene, (19970000), vol. 198, page 203
    - GUPTA; HOO, Plant Mol Biol., (19910000), vol. 17, page 361
    - SMAILUS et al., Syst Synth Biol., (20070000), vol. 1, page 139
    - ITAYA et al., PNAS USA, (20050000), vol. 102, page 15971
    - GIBSON et al., Science, (20080000), vol. 319, page 1215
    - GIBSON et al., PNAS USA, (20080000), vol. 105, no. 51, pages 20404 - 9
    - BRADSHAW et al., Nucleic Acids Research, (19950000), vol. 23, pages 4850 - 56
    - GIBSON et al., Science, (20100000), vol. 329, no. 5987, pages 52 - 6
    - "GenBank", Database accession no. L43967
    - "GenBank", Database accession no. U00089.2
    - AZEVEDO et al., PNAS USA, (19930000), vol. 90, page 6047
    - HEUER et al., Electrophoresis, (19980000), vol. 19, page 486
    - KUSPA et al., PNAS USA, (19890000), vol. 86, page 8917
    - KOZAK, Gene, (19990000), vol. 234, page 187
    - KORNBERG, Trends Cell Biol., (19990000), vol. 9, page M46
    - BELFORT; ROBERTS, Nucleic Acids Res, (19970000), vol. 25, page 3379
    - STINCHCOMB et al., PNAS USA, (19800000), vol. 77, page 4559
    - D. G. GIBSON et al., PNAS USA, (20080000), vol. 105, pages 20404 - 9
    - ARAKI, K. et al., Nucleic Acids Res, (19970000), vol. 25, pages 868 - 872
    - NOSKOV, V.N. et al., Nucl. Acids Res., (20100000), vol. 38, pages 2570 - 76
    - LARTIGUE, C. et al., Science, (20090000), vol. 325, pages 1693 - 96
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.