blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2796138

EP2796138 - Antibiotic compositions for treatment of conjunctivitis [Right-click to bookmark this link]
Former [2014/44]Antibiotic compositions for treatment of the eye, ear and nose
[2016/29]
StatusOpposition rejected
Status updated on  08.02.2019
Database last updated on 31.08.2024
FormerThe patent has been granted
Status updated on  21.10.2018
Most recent event   Tooltip08.02.2019Opposition rejectedpublished on 13.03.2019  [2019/11]
Applicant(s)For all designated states
ALCON PHARMACEUTICALS LIMITED
Route des Arsenaux 41
1701 Fribourg / CH
[2014/44]
Inventor(s)01 / Cagle, Gerald
6309 Greenway
Fort Woth, TX Texas 76116 / US
02 / Abshire, Robert L.
3001 Gunnison Trail
Fort Woth, TX Texas 76116 / US
03 / Stroman, David W.
7214 Native Oak Lane
Irving, TX Texas 75063 / US
04 / Yanni, John M.
2821 Donnybrook Drive
Burleson, TX Texas 76028 / US
 [2014/44]
Representative(s)Stierwald, Michael, et al
Novartis Pharma AG
Patent Department
Forum 1
Novartis Campus
4056 Basel / CH
[N/P]
Former [2016/33]Best, Michael
Lederer & Keller
Patentanwälte Partnerschaft mbB
Unsöldstrasse 2
80538 München / DE
Former [2014/44]Schiener, Jens, et al
Lederer & Keller
Patentanwälte Partnerschaft mbB
Unsöldstrasse 2
80538 München / DE
Application number, filing date14176366.429.09.1999
[2014/44]
Priority number, dateUS19980102504P30.09.1998         Original published format: US 102504 P
US19980102506P30.09.1998         Original published format: US 102506 P
[2014/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2796138
Date:29.10.2014
Language:EN
[2014/44]
Type: B1 Patent specification 
No.:EP2796138
Date:17.08.2016
Language:EN
[2016/33]
Search report(s)(Supplementary) European search report - dispatched on:EP02.10.2014
ClassificationIPC:A61K31/435, A61K31/47, A61K31/535, A61K31/57, A61P27/02, A61P27/16, A61K45/06
[2014/44]
CPC:
A61K45/06 (EP); A61K31/5365 (KR); A61K31/4709 (EP);
A61K31/5383 (EP); A61K31/57 (EP); A61K9/0043 (EP);
A61K9/0046 (EP); A61K9/0048 (EP); A61P11/02 (EP);
A61P11/06 (EP); A61P27/02 (EP); A61P27/16 (EP);
A61P29/00 (EP); A61P31/00 (EP); A61P31/02 (EP);
A61P31/04 (EP); A61P43/00 (EP) (-)
C-Set:
A61K31/4709, A61K2300/00 (EP);
A61K31/5383, A61K2300/00 (EP);
A61K31/57, A61K2300/00 (EP);
A61K31/57, A61K31/47 (EP);
A61K31/57, A61K31/535 (EP)
(-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2015/31]
Former [2014/44]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE 
TitleGerman:Antibiotische Zusammensetzungen zur Behandlung von Konjunktivitis[2016/29]
English:Antibiotic compositions for treatment of conjunctivitis[2016/29]
French:Compositions antibiotiques pour le traitement de la conjonctivite[2016/29]
Former [2014/44]Antibiotische Zusammensetzungen zur Behandlung der Augen, der Ohren und der Nase
Former [2014/44]Antibiotic compositions for treatment of the eye, ear and nose
Former [2014/44]Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez
Examination procedure12.06.2015Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time
16.06.2015Amendment by applicant (claims and/or description)
16.06.2015Examination requested  [2015/31]
22.07.2015Despatch of a communication from the examining division (Time limit: M04)
04.08.2015Reply to a communication from the examining division
14.06.2016Cancellation of oral proceeding that was planned for 16.06.2016
16.06.2016Date of oral proceedings (cancelled)
27.06.2016Communication of intention to grant the patent
29.06.2016Fee for grant paid
29.06.2016Fee for publishing/printing paid
29.06.2016Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP03020587.6  / EP1384478
EP10176412.4  / EP2269602
EP99956504.7  / EP1117401
Opposition(s)Opponent(s)01  17.05.2017    ADMISSIBLE
Becker, Eberhard
Bavariastraße 7
80336 München / DE
Opponent's representative
Becker, Eberhard, et al, et al
Becker Kurig & Partner
Patentanwälte mbB
Bavariastraße 7
80336 München / DE
 [N/P]
Former [2017/25]
Opponent(s)01  17.05.2017    ADMISSIBLE
Becker, Eberhard
Bavariastraße 7
80336 München / DE
Opponent's representative
Becker, Eberhard, et al, et al
Patentanwälte
Becker, Kurig, Straus
Bavariastrasse 7
80336 München / DE
23.06.2017Invitation to proprietor to file observations on the notice of opposition
03.11.2017Reply of patent proprietor to notice(s) of opposition
10.09.2018Legal effect of rejection of opposition [2019/11]
10.09.2018Date of oral proceedings
22.10.2018Despatch of minutes of oral proceedings
22.10.2018Date of despatch of rejection of opposition
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
16.06.2015Request for further processing filed
16.06.2015Full payment received (date of receipt of payment)
Request granted
07.07.2015Decision despatched
The application is deemed to be withdrawn due to non-payment of the examination fee
16.06.2015Request for further processing filed
16.06.2015Full payment received (date of receipt of payment)
Request granted
07.07.2015Decision despatched
The application is deemed to be withdrawn due to non-payment of designation fees
SE, PT, NL, MC, LU, IT, IE, GR, GB, FR, FI, ES, DK, DE, CY, CH, BE, AT
16.06.2015Request for further processing filed
16.06.2015Full payment received (date of receipt of payment)
Request granted
07.07.2015Decision despatched
16.06.2015Request for further processing filed
16.06.2015Full payment received (date of receipt of payment)
Request granted
07.07.2015Decision despatched
Fees paidRenewal fee
09.07.2014Renewal fee patent year 03
09.07.2014Renewal fee patent year 04
09.07.2014Renewal fee patent year 05
09.07.2014Renewal fee patent year 06
09.07.2014Renewal fee patent year 07
09.07.2014Renewal fee patent year 08
09.07.2014Renewal fee patent year 09
09.07.2014Renewal fee patent year 10
09.07.2014Renewal fee patent year 11
09.07.2014Renewal fee patent year 12
09.07.2014Renewal fee patent year 13
09.07.2014Renewal fee patent year 14
09.07.2014Renewal fee patent year 15
09.07.2014Renewal fee patent year 16
11.09.2015Renewal fee patent year 17
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT17.08.2016
CY17.08.2016
FI17.08.2016
MC17.08.2016
SE17.08.2016
IE29.09.2016
LU29.09.2016
[2018/34]
Former [2017/40]AT17.08.2016
FI17.08.2016
MC17.08.2016
SE17.08.2016
IE29.09.2016
LU29.09.2016
Former [2017/12]AT17.08.2016
FI17.08.2016
SE17.08.2016
Former [2017/10]FI17.08.2016
SE17.08.2016
Documents cited:Search[XY]WO9001933  (ALCON LAB INC [US]) [X] 1,2 * the whole document * [Y] 1-9;
 [XY]US4990517  (PETERSEN UWE [DE], et al) [X] 1,2 * column 59, lines 19-22; claim - * [Y] 1-9;
 [AD]US5223493  (BOLTRALIK JOHN J [US]) [AD] 1-9 * the whole document *;
 [A]EP0550903  (BAYER AG [DE]) [A] 1-9 * page 22, line 56 - page 23, line 6; claim - *;
 [A]DE4424369  (BAYER AG [DE]) [A] 1-9 * the whole document *;
 [XY]WO9639146  (BAYER AG [US]) [X] 1,2 * the whole document * [Y] 1-9;
 [XDY]US5607942  (PETERSEN UWE [DE], et al) [XD] 1,2 * column 56, lines 27-30 * [Y] 1-9;
 [YP]WO9915172  (BAYER AG [DE], et al) [YP] 1-9 * the whole document *;
 [E]WO0189485  (HANMI PHARM IND CO LTD [KR]) [E] 1-9 * the whole document *;
 [XPY]  - KRASEMANN, C. (1) ET AL, "Efficacy of moxifloxacin against Staphylococcus aureus in respiratory tract and skin and skin structure infections.", JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, (JULY, 1999) VOL. 44, NO. SUPPL. A, PP. 150. MEETING INFO.: 21ST INTERNATIONAL CONGRESS OF CHEMOTHERAPY BIRMINGHAM, ENGLAND, UK JULY 4-7, 1999, (19990707), XP000892776 [XP] 1,2 * the whole document * [Y] 1-9
 [AP]  - ELIES W., "[Novel fluoroquinolones in the treatment of ENT infections]. NEUERE FLUORCHINOLONE BEI DER THERAPIE VON HNO-INFEKTIONEN.", CHEMOTHERAPIE JOURNAL, (1998) 7/3 (93-97)., (1998), XP000892813 [AP] 1-9 * page 95, column 1 *
 [Y]  - WOODCOCK J M ET AL, In vitro activity of BAY 12-8039, a new fluoroquinolone., ANTIMICROBIAL AGENTS AND CHEMOTHERAPY JAN 1997 LNKD- PUBMED:8980763, VOL. 41, NR. 1, PAGE(S) 101 - 106, (199701), ISSN 0066-4804, XP002608942 [Y] 1-9 * See table 1 *
 [T]  - STROMAN D W ET AL, "In Vitro and In Vivo Potency of Moxifloxacin and Moxifloxacin Ophthalmic Solution 0.5%, A New Topical Fluoroquinolone", SURVEY OF OPHTHALMOLOGY, SURVEY OF OPHTHALMOLOGY INC, XX, vol. 50, no. 6, ISSN 0039-6257, (20051101), pages S16 - S31, (20051101), XP025381754 [T] * the whole document *
 [T]  - ROBERTSON S M ET AL, "Ocular Pharmacokinetics of Moxifloxacin After Topical Treatment of Animals and Humans", SURVEY OF OPHTHALMOLOGY, SURVEY OF OPHTHALMOLOGY INC, XX, vol. 50, no. 6, ISSN 0039-6257, (20051101), pages S32 - S45, (20051101), XP025381755 [T] * the whole document *
 [Y]  - FRANCOIS J ET AL, "Ocular infection due to gram negative and non fermentative microorganisms", EMBASE,, (19720101), XP002619096 [Y] 1-9 * the whole document *
    [ ] - OPHTHALM.RES. 1972, (1972), vol. 3, no. 2, pages 114 - 121
 [Y]  - THIEL H-J ET AL, "Adherence and pathogenesis of staphylococcus aureus and pseudomonas aeruginosa in corneal infections", EXPERIMENTAL EYE RESEARCH, ACADEMIC PRESS LTD, LONDON, vol. 55, doi:10.1016/0014-4835(92)90948-R, ISSN 0014-4835, (19920901), page 208, (19920901), XP022972448 [Y] 1-9 * abstract *

DOI:   http://dx.doi.org/10.1016/0014-4835(92)90948-R
 [Y]  - KHATER T T ET AL, "Infectious crystalline keratopathy caused by gram-negative bacteria", AMERICAN JOURNAL OF OPHTHALMOLOGY, ELSEVIER, AMSTERDAM, NL, (19970701), vol. 124, no. 1, ISSN 0002-9394, pages 19 - 23, XP009158432 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0002-9394(14)71638-1
 [Y]  - PENLAND R L ET AL, "Stenotrophomonas maltophilia ocular infections", ARCHIVES OF OPHTHALMOLOGY, AMERICAN MEDICAL ASSOCIATION, US, (19960401), vol. 114, no. 4, ISSN 0003-9950, pages 433 - 436, XP009158431 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1001/archopht.1996.01100130429013
 [Y]  - KNAUF H P ET AL, "Susceptibility of corneal and conjunctival pathogens to ciprofloxacin", CORNEA: THE JOURNAL OF CORNEA AND EXTERNAL DISEASE, LIPPINCOTT WILLIAMS & WILKINS, US, (19960101), vol. 15, no. 1, ISSN 0277-3740, pages 66 - 71, XP009158430 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1097/00003226-199601000-00012
 [Y]  - GRODEN L R ET AL, "Lid flora in blepharitis", CORNEA: THE JOURNAL OF CORNEA AND EXTERNAL DISEASE, LIPPINCOTT WILLIAMS & WILKINS, US, (19910101), vol. 10, no. 1, ISSN 0277-3740, pages 50 - 53, XP009158429 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1097/00003226-199110010-00010
 [Y]  - KELLY L D ET AL, "Bacteroides fragilis endophthalmitis: a case report", CANADIAN JOURNAL OF OPHTHALMOLOGY, CANADIAN OPHTHALMOLOGICAL SOCIETY, CA, (19900601), vol. 25, no. 4, ISSN 0008-4182, pages 208 - 209, XP009158428 [Y] 1-9 * the whole document *
 [Y]  - STERN G A ET AL, "EXPERIMENTAL BACTEROIDES-FRAGILIS KERATITIS", ARCHIVES OF OPHTHALMOLOGY, AMERICAN MEDICAL ASSOCIATION, US, (19780101), vol. 96, no. 12, ISSN 0003-9950, pages 2264 - 2266, XP009158433 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1001/archopht.1978.03910060560020
 [Y]  - ZABEL R W ET AL, "Acinetobacter corneal ulcer after penetrating keratoplasty", AMERICAN JOURNAL OF OPHTHALMOLOGY, ELSEVIER, AMSTERDAM, NL, (19890601), vol. 107, no. 6, ISSN 0002-9394, pages 677 - 678, XP009158434 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1016/0002-9394(89)90270-5
 [Y]  - WEISS A ET AL, "Acute conjunctivitis in childhood.", THE JOURNAL OF PEDIATRICS JAN 1993, (199301), vol. 122, no. 1, ISSN 0022-3476, pages 10 - 14, XP023074402 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1016/0045-9380(94)90022-1
 [Y]  - KROHN M A ET AL, "The bacterial etiology of conjunctivitis in early infancy. Eye Prophylaxis Study Group", AMERICAN JOURNAL OF EPIDEMIOLOGY, OXFORD UNIVERSITY PRESS, US, (19930901), vol. 138, no. 5, ISSN 0002-9262, pages 326 - 332, XP009166253 [Y] 1-9 * the whole document *
by applicantUS5223493
 US5607942
OppositionWO9001933
 WO9321903
 WO9729752
 WO0018366
 EP2269602
 EP2796138
    - Mitchell H Friedlaender, "A review of the causes and treatment of bacterial and allergic conjunctivitis", CLINICAL THERAPEUTICS., vol. 17, no. 5, (19950101), pages 800 - 810, XP055383283

DOI:   http://dx.doi.org/10.1016/0149-2918(95)80058-1
    - Adenis J P; Colin J; Verin P; Riss I; Saint-Blancat P, "Ciprofloxacin ophthalmic solution in the treatment of conjunctivitis and blepharitis: a comparison with fusidic acid", EUROPEAN JOURNAL OF OPHTHALMOlogy, vol. 6, no. 4, (19960000), pages 368 - 374, XP009186698
    - G S Ogawa, Hyndiuk R A, "The fluoroquinolones: new antibiotics in ophthalmology", International Ophthalmology Clinics, vol. 33, no. 4, (19930000), pages 59 - 68, XP055383292

DOI:   http://dx.doi.org/10.1097/00004397-199303340-00007
    - Gross R D; Hoffman R O; Lindsay R N, "A comparison of ciprofloxacin and tobramycin in bacterial conjunctivitis in children", Clinical Pediatrics, vol. 36, no. 8, (19970800), pages 435 - 444, XP009186699

DOI:   http://dx.doi.org/10.1177/000992289703600801
    - Adenis J P; Colin J; Verin P; Saint-Blancat P; Malet F, "Ciprofloxacin ophthalmic solution versus rifamycin ophthalmic solution for the treatment of conjunctivitis and blepharitis", EUROPEAN JOURNAL OF OPHTHALMOlogy, vol. 5, no. 2, (19950400), pages 82 - 87, XP009186697
    - FRIEDLAENDER M.H., "Twice-a-day versus Four-times-a-day Ofloxacin Treatment of External Ocular Infections.", The CLAO journal, (19980100), vol. 24, no. 1, pages 48 - 51, XP055383312
    - SCHMITZ F.J. et al., "Relationship between ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and moxifloxacin (BAY 12-8039) MICs and mutations in grlA, grlB, gyrA and gyrB in 116 unrelated clinicial isolates of Staphylococcus aureus.", The Journal of Antimicrobial Chemotherapy, (19980400), vol. 41, no. 4, pages 481 - 484, XP001035008

DOI:   http://dx.doi.org/10.1093/jac/41.4.481
    - "Fluoroquinolones for the eye", DTB Journal, vol. 32, no. 10, (19941020), pages 78 - 79, URL: doi: 10.1136/dtb.1994.321078, XP055383321

DOI:   http://dx.doi.org/10.1136/dtb.1994.321078
    - WOODCOCK J.M. et al., "In vitro activity of Bay 12-8039, a new fluoroquinolone", Antimicrobial Agents and Chemotherapy, (19970100), vol. 41, no. 1, pages 101 - 106, XP002608942
    - Sean P. Donahue, et al.,, "Common Ocular Infections A Prescriber`s Guide", Drugs, vol. 52, no. 4, (19961000), pages 526 - 540, XP055383330
    - Giorgio Ciprandi et al.,, "Topical acetylsalicyclic acid in the treatment of allergic pollinosic conjunctivitis", J Invest Clin Immunol., vol. 2, no. 1, (19920100), pages 15 - 18, XP055383335
    - Bala; Chin M; Logan C N; Amin A T; Marnett T; Boutaud L J; Oates O; J A, "Acetylation of prostaglandin H2 synthases by aspirin is inhibited by redox cycling of the peroxidase (NIH Public Access Author Manuscript)", Biochemical Pharmacology,, vol. 75, no. 7, (20080401), pages 1472 - 1481, XP055383347

DOI:   http://dx.doi.org/10.1016/j.bcp.2007.12.005
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.