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Extract from the Register of European Patents

EP About this file: EP3036543

EP3036543 - DIAGNOSTIC TESTS AND METHODS FOR ASSESSING SAFETY, EFFICACY OR OUTCOME OF ALLERGEN-SPECIFIC IMMUNOTHERAPY (SIT) [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.07.2020
Database last updated on 13.09.2024
FormerThe patent has been granted
Status updated on  17.05.2019
FormerGrant of patent is intended
Status updated on  01.01.2019
FormerExamination is in progress
Status updated on  19.05.2017
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Regeneron Pharmaceuticals, Inc.
777 Old Saw Mill River Road
Tarrytown, NY 10591 / US
[2016/26]
Inventor(s)01 / YANCOPOULOS, George D.
1519 Baptist Church Road
Yorktown Heights, NY 10598 / US
02 / ORENGO, Jamie
17 Maple Moor Lane
Cortlandt Manor, NY 10567 / US
 [2016/26]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2019/25]J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2016/26]Bentham, Andrew
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date14761497.822.08.2014
[2016/26]
WO2014US52295
Priority number, dateUS201361869214P23.08.2013         Original published format: US 201361869214 P
[2016/26]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2015027154
Date:26.02.2015
Language:EN
[2015/08]
Type: A2 Application without search report 
No.:EP3036543
Date:29.06.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 26.02.2015 takes the place of the publication of the European patent application.
[2016/26]
Type: B1 Patent specification 
No.:EP3036543
Date:19.06.2019
Language:EN
[2019/25]
Search report(s)International search report - published on:EP30.04.2015
ClassificationIPC:G01N33/50
[2016/26]
CPC:
G01N33/6854 (EP,US); A61K49/0008 (US); G01N33/502 (EP,US);
G01N33/5088 (US); G01N2800/24 (US); G01N2800/52 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/26]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:DIAGNOSTISCHE TESTS UND VERFAHREN ZUR BEURTEILUNG DER SICHERHEIT, DER WIRKSAMKEIT ODER DES ERGEBNISSES EINER ALLERGENSPEZIFISCHEN IMMUNTHERAPIE[2016/26]
English:DIAGNOSTIC TESTS AND METHODS FOR ASSESSING SAFETY, EFFICACY OR OUTCOME OF ALLERGEN-SPECIFIC IMMUNOTHERAPY (SIT)[2016/26]
French:TESTS DIAGNOSTIQUES ET MÉTHODES POUR ÉVALUER L'INNOCUITÉ, L'EFFICACITÉ OU LE RÉSULTAT D'UNE IMMUNOTHÉRAPIE SPÉCIFIQUE DE L'ALLERGÈNE (ITS)[2016/26]
Entry into regional phase15.03.2016National basic fee paid 
15.03.2016Designation fee(s) paid 
15.03.2016Examination fee paid 
Examination procedure15.03.2016Amendment by applicant (claims and/or description)
15.03.2016Examination requested  [2016/26]
17.05.2017Despatch of a communication from the examining division (Time limit: M06)
24.11.2017Reply to a communication from the examining division
25.01.2018Despatch of a communication from the examining division (Time limit: M02)
29.03.2018Reply to a communication from the examining division
06.06.2018Despatch of a communication from the examining division (Time limit: M04)
15.10.2018Reply to a communication from the examining division
02.01.2019Communication of intention to grant the patent
07.05.2019Fee for grant paid
07.05.2019Fee for publishing/printing paid
07.05.2019Receipt of the translation of the claim(s)
Divisional application(s)EP19178233.3  / EP3564671
Opposition(s)03.06.2020No opposition filed within time limit [2020/33]
Fees paidRenewal fee
24.08.2016Renewal fee patent year 03
23.08.2017Renewal fee patent year 04
23.08.2018Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU22.08.2014
AL19.06.2019
AT19.06.2019
CY19.06.2019
CZ19.06.2019
DK19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
IT19.06.2019
LT19.06.2019
LV19.06.2019
MC19.06.2019
MK19.06.2019
MT19.06.2019
NL19.06.2019
PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SI19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
LU22.08.2019
BE31.08.2019
FR31.08.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
[2022/31]
Former [2021/34]HU22.08.2014
AL19.06.2019
AT19.06.2019
CY19.06.2019
CZ19.06.2019
DK19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
IT19.06.2019
LT19.06.2019
LV19.06.2019
MC19.06.2019
MT19.06.2019
NL19.06.2019
PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SI19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
LU22.08.2019
BE31.08.2019
FR31.08.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2021/32]HU22.08.2014
AL19.06.2019
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CZ19.06.2019
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ES19.06.2019
FI19.06.2019
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IT19.06.2019
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MC19.06.2019
NL19.06.2019
PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SI19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
LU22.08.2019
BE31.08.2019
FR31.08.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2021/26]AL19.06.2019
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DK19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
IT19.06.2019
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LV19.06.2019
MC19.06.2019
NL19.06.2019
PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SI19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
LU22.08.2019
BE31.08.2019
FR31.08.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2020/37]AL19.06.2019
AT19.06.2019
CZ19.06.2019
DK19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
IT19.06.2019
LT19.06.2019
LV19.06.2019
MC19.06.2019
NL19.06.2019
PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SI19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
LU22.08.2019
BE31.08.2019
FR31.08.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2020/36]AL19.06.2019
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CZ19.06.2019
DK19.06.2019
EE19.06.2019
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FI19.06.2019
HR19.06.2019
IT19.06.2019
LT19.06.2019
LV19.06.2019
MC19.06.2019
NL19.06.2019
PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
LU22.08.2019
FR31.08.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2020/25]AL19.06.2019
AT19.06.2019
CZ19.06.2019
DK19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
IT19.06.2019
LT19.06.2019
LV19.06.2019
MC19.06.2019
NL19.06.2019
PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
LU22.08.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
PT21.10.2019
IS24.02.2020
Former [2020/24]AL19.06.2019
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PL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
PT21.10.2019
IS24.02.2020
Former [2020/22]AL19.06.2019
AT19.06.2019
CZ19.06.2019
DK19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
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IT19.06.2019
LT19.06.2019
LV19.06.2019
NL19.06.2019
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RS19.06.2019
SE19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2020/17]AL19.06.2019
AT19.06.2019
CZ19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
IT19.06.2019
LT19.06.2019
LV19.06.2019
NL19.06.2019
RO19.06.2019
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SE19.06.2019
SK19.06.2019
SM19.06.2019
TR19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2020/13]AL19.06.2019
AT19.06.2019
CZ19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
IT19.06.2019
LT19.06.2019
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NL19.06.2019
RO19.06.2019
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SE19.06.2019
SK19.06.2019
SM19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2020/12]AL19.06.2019
AT19.06.2019
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FI19.06.2019
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LT19.06.2019
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NL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SK19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
IS19.10.2019
PT21.10.2019
Former [2020/11]AL19.06.2019
AT19.06.2019
CZ19.06.2019
EE19.06.2019
ES19.06.2019
FI19.06.2019
HR19.06.2019
LT19.06.2019
LV19.06.2019
NL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
SK19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
PT21.10.2019
Former [2020/10]AL19.06.2019
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CZ19.06.2019
FI19.06.2019
HR19.06.2019
LT19.06.2019
LV19.06.2019
NL19.06.2019
RO19.06.2019
RS19.06.2019
SE19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
PT21.10.2019
Former [2020/09]AL19.06.2019
CZ19.06.2019
FI19.06.2019
HR19.06.2019
LT19.06.2019
LV19.06.2019
NL19.06.2019
RS19.06.2019
SE19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
Former [2020/07]AL19.06.2019
FI19.06.2019
HR19.06.2019
LT19.06.2019
LV19.06.2019
NL19.06.2019
RS19.06.2019
SE19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
Former [2019/51]AL19.06.2019
FI19.06.2019
HR19.06.2019
LT19.06.2019
LV19.06.2019
RS19.06.2019
SE19.06.2019
BG19.09.2019
NO19.09.2019
GR20.09.2019
Former [2019/50]AL19.06.2019
FI19.06.2019
HR19.06.2019
LT19.06.2019
LV19.06.2019
RS19.06.2019
SE19.06.2019
NO19.09.2019
GR20.09.2019
Former [2019/49]AL19.06.2019
FI19.06.2019
HR19.06.2019
LT19.06.2019
SE19.06.2019
NO19.09.2019
Former [2019/48]FI19.06.2019
LT19.06.2019
SE19.06.2019
NO19.09.2019
Former [2019/47]FI19.06.2019
LT19.06.2019
NO19.09.2019
Cited inInternational search[X]  - P. A. WÜRTZEN ET AL, "A double-blind placebo-controlled birch allergy vaccination study II: correlation between inhibition of IgE binding, histamine release and facilitated allergen presentation", CLINICAL & EXPERIMENTAL ALLERGY, (20080801), vol. 38, no. 8, doi:10.1111/j.1365-2222.2008.03020.x, ISSN 0954-7894, pages 1290 - 1301, XP055154245 [X] 1-3,33 * the whole document * * In particular: Title; Abstract; Materials and methods section; Fig. 1. *

DOI:   http://dx.doi.org/10.1111/j.1365-2222.2008.03020.x
 [X]  - CHRISTIAN MÖBS ET AL, "Birch pollen immunotherapy results in long-term loss of Bet v 1-specific TH2 responses, transient TR1 activation, and synthesis of IgE-blocking antibodies", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, (20121101), vol. 130, no. 5, doi:10.1016/j.jaci.2012.07.056, ISSN 0091-6749, pages 1108 - 1116.e6, XP055154058 [X] 1-3,33 * the whole document * * In particular: Title; Abstract; Methods section (online repository at the end of the document); Fig. E3. *

DOI:   http://dx.doi.org/10.1016/j.jaci.2012.07.056
 [X]  - A. BABAKHIN ET AL, "Experimental desensitisation using a modified allergen adsorbed onto a synthetic Immunomodulator in a murine model of allergic asthma.", ALLERGY, (20070613), vol. 62, no. Suppl. 83, ISSN 0105-4538, page 252, XP055154300 [X] 1-5,33 * the whole document *
 [X]  - BABAKHIN ET AL, "Allergen-specific Immunotherapy Using A Highly Modified Allergen And The Immunomodulator Polyoxidonium In A Murine Model Of Allergic Asthma", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ELSEVIER, AMSTERDAM, NL, (20070101), vol. 119, no. 1, doi:10.1016/J.JACI.2006.11.252, ISSN 0091-6749, page S59, XP005756142 [X] 1-5,33 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.jaci.2006.11.252
 [X]  - KATARZYNA NIESPODZIANA ET AL, "A hypoallergenic cat vaccine based on Fel d 1-derived peptides fused to hepatitis B PreS", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, (20110601), vol. 127, no. 6, doi:10.1016/j.jaci.2011.02.004, ISSN 0091-6749, pages 1562 - 1570.e6, XP055014054 [X] 66-72 * the whole document * * In particular: Title; Abstract; Materials and methods section, in essence p. 1563-1564, bridging paragraph. *

DOI:   http://dx.doi.org/10.1016/j.jaci.2011.02.004
 [XY]  - TERESA E. TWAROCH ET AL, "Carrier-bound, nonallergenic Ole e 1 peptides for vaccination against olive pollen allergy", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, (20110701), vol. 128, no. 1, doi:10.1016/j.jaci.2011.03.011, ISSN 0091-6749, pages 178 - 184.e7, XP055014321 [X] 66 * the whole document * * In particular: Title; Abstract; Methods section on page 184e.1. * [Y] 67-72

DOI:   http://dx.doi.org/10.1016/j.jaci.2011.03.011
 [Y]  - GIALLONGO A ET AL, "IgE and IgG antibodies compete for antigenic determinants of Parietaria officinalis allergen", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 17, no. 8, doi:10.1016/0161-5890(80)90095-4, ISSN 0161-5890, (19800801), pages 1019 - 1024, (19800801), XP023680141 [Y] 67-72 * the whole document * * In particular: Title and abstract; Materials and methods section; Table 1; Fig. 4; p. 1022-1023, bridging paragraph. *

DOI:   http://dx.doi.org/10.1016/0161-5890(80)90095-4
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.