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Extract from the Register of European Patents

EP About this file: EP2976070

EP2976070 - ANTI-INFLAMMATORY SYNERGISTIC COMBINATIONS OF ASTAXANTHIN WITH LYCOPENE AND CARNOSIC ACID [Right-click to bookmark this link]
Former [2016/04]ASTAXANTHIN ANTI-INFLAMMATORY SYNERGISTIC COMBINATIONS
[2020/50]
StatusNo opposition filed within time limit
Status updated on  18.03.2022
Database last updated on 04.11.2024
FormerThe patent has been granted
Status updated on  09.04.2021
FormerGrant of patent is intended
Status updated on  25.11.2020
FormerExamination is in progress
Status updated on  14.09.2018
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 09.10.2024  [2024/41]
Applicant(s)For all designated states
Lycored Ltd.
P.O. Box 320
84102 Beer Sheva / IL
[2021/19]
Former [2016/04]For all designated states
Lycored Ltd.
P.O. Box 320
84102 Beer Sheva / IL
Inventor(s)01 / LEVY, Rachel
8 Livna St.
84965 Omer / IL
02 / HADAD, Nurit
P.O. Box 320
84102 Beer Sheva / IL
03 / SEDLOV, Tanya
27 Levin Kipnis St.
84496 Beer Sheva / IL
04 / ZELKHA, Morris
4 Givati St.
52232 Ramat Gan / IL
 [2016/04]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[2021/19]
Former [2016/04]Wichmann, Hendrik
Wuesthoff & Wuesthoff
Patentanwälte PartG mbB
Schweigerstraße 2
81541 München / DE
Application number, filing date14768070.613.03.2014
[2016/04]
WO2014IL50272
Priority number, dateUS201361803191P19.03.2013         Original published format: US 201361803191 P
[2016/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014147610
Date:25.09.2014
Language:EN
[2014/39]
Type: A1 Application with search report 
No.:EP2976070
Date:27.01.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 25.09.2014 takes the place of the publication of the European patent application.
[2016/04]
Type: B1 Patent specification 
No.:EP2976070
Date:12.05.2021
Language:EN
[2021/19]
Search report(s)International search report - published on:IL25.09.2014
(Supplementary) European search report - dispatched on:EP10.10.2016
ClassificationIPC:A61K31/122, A61K31/01, A61K31/192, A61P29/00
[2016/04]
CPC:
A61K31/122 (EP,US); A23L33/105 (EP,US); A61K31/01 (EP,US);
A61K31/015 (EP,US); A61K31/047 (EP,US); A61K31/192 (EP,US);
A61K31/355 (EP,US); A61K36/81 (US); A61K9/0053 (US);
A61P29/00 (EP); A61P43/00 (EP); A23V2002/00 (US);
A61K2300/00 (EP,US); Y02A50/30 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/04]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:ENTZÜNDUNGSHEMMENDE SYNERGISTISCHE KOMBINATIONEN ENTHALTEND ASTAXANTHIN, LYCOPIN UND CARNOSINSÄURE[2020/50]
English:ANTI-INFLAMMATORY SYNERGISTIC COMBINATIONS OF ASTAXANTHIN WITH LYCOPENE AND CARNOSIC ACID[2020/50]
French:COMBINAISONS ANTI-INFLAMMATOIRES SYNERGIQUES D'ASTAXANTHINE, DE LYCOPÈNE ET D'ACIDE CARNOSIQUE[2020/50]
Former [2016/04]ENTZÜNDUNGSHEMMENDE SYNERGISTISCHE ASTAXANTHINKOMBINATIONEN
Former [2016/04]ASTAXANTHIN ANTI-INFLAMMATORY SYNERGISTIC COMBINATIONS
Former [2016/04]COMBINAISONS SYNERGIQUES D'ASTAXANTHINE ET D'ANTI-INFLAMMATOIRE
Entry into regional phase21.09.2015National basic fee paid 
21.09.2015Search fee paid 
21.09.2015Designation fee(s) paid 
21.09.2015Examination fee paid 
Examination procedure21.09.2015Examination requested  [2016/04]
20.04.2017Amendment by applicant (claims and/or description)
12.09.2018Despatch of a communication from the examining division (Time limit: M04)
11.01.2019Reply to a communication from the examining division
28.10.2019Despatch of a communication from the examining division (Time limit: M04)
30.01.2020Reply to a communication from the examining division
26.11.2020Communication of intention to grant the patent
31.03.2021Fee for grant paid
31.03.2021Fee for publishing/printing paid
31.03.2021Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.09.2018
Opposition(s)15.02.2022No opposition filed within time limit [2022/16]
Fees paidRenewal fee
25.03.2016Renewal fee patent year 03
10.03.2017Renewal fee patent year 04
13.03.2018Renewal fee patent year 05
04.03.2019Renewal fee patent year 06
09.03.2020Renewal fee patent year 07
16.03.2021Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU13.03.2014
AL12.05.2021
AT12.05.2021
CY12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
MC12.05.2021
MK12.05.2021
MT12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SI12.05.2021
SK12.05.2021
SM12.05.2021
TR12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
[2024/41]
Former [2024/29]HU13.03.2014
AL12.05.2021
AT12.05.2021
CY12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
MC12.05.2021
MK12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SI12.05.2021
SK12.05.2021
SM12.05.2021
TR12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2024/22]HU13.03.2014
AL12.05.2021
AT12.05.2021
CY12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
MC12.05.2021
MK12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SI12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2024/20]HU13.03.2014
AL12.05.2021
AT12.05.2021
CY12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
MC12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SI12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2024/18]HU13.03.2014
AL12.05.2021
AT12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
MC12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SI12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/47]AL12.05.2021
AT12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
MC12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SI12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/29]AL12.05.2021
AT12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SI12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/26]AL12.05.2021
AT12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/23]AT12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/10]AT12.05.2021
CZ12.05.2021
DK12.05.2021
EE12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
PT13.09.2021
IS22.12.2021
Former [2022/09]AT12.05.2021
CZ12.05.2021
DK12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RO12.05.2021
RS12.05.2021
SE12.05.2021
SK12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/08]AT12.05.2021
CZ12.05.2021
DK12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RS12.05.2021
SE12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/07]AT12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RS12.05.2021
SE12.05.2021
SM12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2022/04]AT12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
NL12.05.2021
RS12.05.2021
SE12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2021/51]AT12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
RS12.05.2021
SE12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
IS12.09.2021
PT13.09.2021
Former [2021/50]AT12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
SE12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
PT13.09.2021
Former [2021/49]AT12.05.2021
FI12.05.2021
HR12.05.2021
LT12.05.2021
LV12.05.2021
SE12.05.2021
BG12.08.2021
NO12.08.2021
GR13.08.2021
Former [2021/47]AT12.05.2021
FI12.05.2021
LT12.05.2021
BG12.08.2021
Former [2021/46]AT12.05.2021
FI12.05.2021
LT12.05.2021
Documents cited:Search[A]WO2010082205  (LYCORED LTD [IL], et al) [A] 1-15 * the whole document *
 [XI]  - Anonymous, "Higher Nature Astaxanthine and Blackcurrant Capsules Pack of 90: Amazon.co.uk: Health & Personal Care", (20070226), pages 1 - 6, URL: https://www.amazon.co.uk/dp/B000NRVW2U?_encoding=UTF8&isInIframe=0&n=65801031&ref_=dp_proddesc_0&s=drugstore&showDetailProductDesc=1#product-description_feature_div, (20160922), XP055304798 [X] 1,2,6-9 * the whole document * [I] 3-5
 [XI]  - Dorie Greenspan, "Salmon with Tomatoes & Rosemary", (20110723), pages 1 - 3, URL: http://communitytable.parade.com/30359/doriegreenspan/salmon-with-tomatoes-rosemary/, (20160922), XP055304820 [X] 1,2,6-8 * the whole document * [I] 3-5
International search[X]WO2004052351  (DSM IP ASSETS BV [NL], et al);
 [X]WO2009007975  (LYCORED LTD [IL], et al);
 [Y]  - HADAD N ET AL., "The synergistic anti-inflammatory effects of lycopene, lutein, ?- carotene, and carnosic acid combinations via redox-based inhibition of NF-?B signaling.", FREE RADIC BIOL MED., vol. 53, no. 7, (20121001), pages 1381 - 91, URL: http://www.sciencedirect.com/science/article/pii/50891584912004728, (20140618), XP055279495

DOI:   http://dx.doi.org/10.1016/j.freeradbiomed.2012.07.078
 [Y]  - LEE SJ ET AL., "Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation.", MOL CELLS., vol. 16, no. 1, (20030831), pages 97 - 105, URL: http://www.molcells.org/journal/view.html?year=2003&volume=16&number=1&spage=97, (20140618), XP055279498
 [A]  - PALOZZA P ET AL., "Tomato lycopene and inflammatory cascade: basic interactions and clinical implications.", CURR MED CHEM. 2010, vol. 17, no. 23, (20100831), pages 2547 - 63, URL: http://www.eurekaselect.com/71902/article, (20140616), XP055279499

DOI:   http://dx.doi.org/10.2174/092986710791556041
Examination   - Ramses B Toma ET AL, "Lycopene content in raw tomato varieties and tomato products", Journal of Foodservice, doi:10.1111/j.1745-4506.2008.00094.x, (20080401), pages 127 - 132, URL: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1745-4506.2008.00094.x, XP055504862

DOI:   http://dx.doi.org/10.1111/j.1745-4506.2008.00094.x
    - Ademoyegun Olufemi Temitope ET AL, "Fresh Produce  2009 Global Science Books Lycopene Content in Tomatoes (Lycopersicon esculentum Mill): Effect of Thermal Heat and its Health Benefits", (20090101), URL: http://www.globalsciencebooks.info/Online/GSBOnline/images/0906/FP_3(1)/FP_3(1)40-43o.pdf, (20180905), XP055504863
    - Pratik M. Choksi ET AL, "A Review on Lycopene-Extraction, Purification, Stability and Applications", INTERNATIONAL JOURNAL OF FOOD PROPERTIES, US, (20070425), vol. 10, no. 2, doi:10.1080/10942910601052699, ISSN 1094-2912, pages 289 - 298, XP055504864

DOI:   http://dx.doi.org/10.1080/10942910601052699
by applicantWO2010082205
 US5837311
    - RAFI M.M. et al., Mol Nutr Food Res., (20070300), vol. 51, no. 3, pages 333 - 40
    - CHOI, J.S., Nutrition, (20060600), vol. 22, no. 6, pages 668 - 71
    - RAFI, M.M. et al., J Food Sci., (20070100), vol. 72, no. 1, pages 069 - 74
    - FINGL et al., The Pharmacological Basis of Therapeutics, Mack Publishing Co., (19750000), page l
    - Current Protocols in Molecular Biology, (19940000), vol. I-III
    - T. W. GRAHAM SOLOMONSCRAIG FRYHLE, Organic Chemistry
 DE19951009955
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.