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Extract from the Register of European Patents

EP About this file: EP3006571

EP3006571 - HLA GENE MULTIPLEX DNA TYPING METHOD AND KIT [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.06.2019
Database last updated on 13.09.2024
FormerThe patent has been granted
Status updated on  13.07.2018
FormerGrant of patent is intended
Status updated on  06.03.2018
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK
published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Genodive Pharma Inc.
1-19-35 Ryokuen
Izumi-ku
Yokohama-shi
Kanagawa 245-0002 / JP
[2016/15]
Inventor(s)01 / SHIINA, Takashi
5-7-7-501 Kawaraguchi
Ebina-shi Kanagawa 243-0433 / JP
02 / SUZUKI, Shingo
1-18-21-202 Tsumadaminami
Atsugi-shi Kanagawa 243-0814 / JP
03 / WADA, Yuki
2-1-1-603 Asahi-cho
Atsugi-shi Kanagawa 243-0014 / JP
04 / MITSUNAGA, Shigeki
2824-1-A308 Nara-cho
Aoba-ku
Yokohama-shi Kanagawa 227-0036 / JP
05 / INOKO, Hidetoshi
1-19-35 Ryokuen
Izumi-ku
Yokohama-shi Kanagawa 245-0002 / JP
 [2016/16]
Former [2016/15]01 / SHIINA, Takashi
5-7-7-501 Kawaraguchi
Ebina-shi Kanagawa 243-0433 / JP
02 / SUZUKI, Shingo
5-42-36-407 Asahi-cho
Atsugi-shi Kanagawa 243-0014 / JP
03 / WADA, Yuki
2-1-1-603 Asahi-cho
Atsugi-shi Kanagawa 243-0014 / JP
04 / MITSUNAGA, Shigeki
2824-1-A308 Nara-cho
Aoba-ku
Yokohama-shi Kanagawa 227-0036 / JP
05 / INOKO, Hidetoshi
1-19-35 Ryokuen
Izumi-ku
Yokohama-shi Kanagawa 245-0002 / JP
Representative(s)Docherty, Robert Charles
Symbiosis IP Limited
York Biotech Campus
Office 14FA05
Sand Hutton
York, YO41 1LZ / GB
[N/P]
Former [2018/33]Docherty, Robert Charles
Symbiosis IP Limited
NAFIC
Office 14FA05
Sand Hutton
York, North Yorkshire YO41 1LZ / GB
Former [2016/15]Docherty, Robert Charles
Symbiosis IP Limited
106 Heworth Green
York YO31 7TQ / GB
Application number, filing date14795192.509.05.2014
[2016/15]
WO2014JP62433
Priority number, dateJP2013009954709.05.2013         Original published format: JP 2013099547
[2016/15]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014181854
Date:13.11.2014
Language:JA
[2014/46]
Type: A1 Application with search report 
No.:EP3006571
Date:13.04.2016
Language:EN
[2016/15]
Type: B1 Patent specification 
No.:EP3006571
Date:15.08.2018
Language:EN
[2018/33]
Search report(s)International search report - published on:JP13.11.2014
(Supplementary) European search report - dispatched on:EP23.01.2017
ClassificationIPC:C12Q1/6881
[2018/11]
CPC:
C12Q1/6881 (EP,US); C12Q2600/156 (EP,US); C12Q2600/16 (EP,US)
Former IPC [2016/15]C12Q1/68, C12N15/09
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/15]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN UND KIT FÜR MULTIPLEX-DNA-TYPISIERUNG VON HLA-GENEN[2016/15]
English:HLA GENE MULTIPLEX DNA TYPING METHOD AND KIT[2016/15]
French:MÉTHODE ET KIT DE TYPAGE MULTIPLEX DE L'ADN DU GÈNE HLA[2016/15]
Entry into regional phase01.12.2015Translation filed 
01.12.2015National basic fee paid 
01.12.2015Search fee paid 
01.12.2015Designation fee(s) paid 
01.12.2015Examination fee paid 
Examination procedure01.12.2015Examination requested  [2016/15]
11.08.2017Amendment by applicant (claims and/or description)
27.09.2017Despatch of communication of loss of particular rights: Priority 0001
03.10.2017Request for decision received: Priority
25.10.2017Result of request for decision (Priority): Request accepted
07.03.2018Communication of intention to grant the patent
04.07.2018Fee for grant paid
04.07.2018Fee for publishing/printing paid
04.07.2018Receipt of the translation of the claim(s)
Opposition(s)16.05.2019No opposition filed within time limit [2019/30]
Request for further processing for:03.10.2017Request for further processing filed
Fees paidRenewal fee
11.04.2016Renewal fee patent year 03
04.04.2017Renewal fee patent year 04
10.05.2018Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU09.05.2014
AL15.08.2018
AT15.08.2018
CY15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
MK15.08.2018
MT15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
TR15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
PT15.12.2018
IE09.05.2019
LU09.05.2019
[2022/31]
Former [2021/34]HU09.05.2014
AL15.08.2018
AT15.08.2018
CY15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
MT15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
TR15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
PT15.12.2018
IE09.05.2019
LU09.05.2019
Former [2021/32]HU09.05.2014
AL15.08.2018
AT15.08.2018
CY15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
TR15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
PT15.12.2018
IE09.05.2019
LU09.05.2019
Former [2021/26]AL15.08.2018
AT15.08.2018
CY15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
TR15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
PT15.12.2018
IE09.05.2019
LU09.05.2019
Former [2020/29]AL15.08.2018
AT15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
TR15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
PT15.12.2018
IE09.05.2019
LU09.05.2019
Former [2020/21]AL15.08.2018
AT15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
TR15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
IE09.05.2019
LU09.05.2019
Former [2020/16]AL15.08.2018
AT15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
TR15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
LU09.05.2019
Former [2020/13]AL15.08.2018
AT15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
LU09.05.2019
Former [2020/07]AL15.08.2018
AT15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
MC15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/37]AL15.08.2018
AT15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SI15.08.2018
SK15.08.2018
SM15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/26]AL15.08.2018
AT15.08.2018
CZ15.08.2018
DK15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SK15.08.2018
SM15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/23]AL15.08.2018
AT15.08.2018
CZ15.08.2018
EE15.08.2018
ES15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
SK15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/22]AL15.08.2018
AT15.08.2018
CZ15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
NL15.08.2018
PL15.08.2018
RO15.08.2018
RS15.08.2018
SE15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/21]AL15.08.2018
AT15.08.2018
FI15.08.2018
HR15.08.2018
IT15.08.2018
LT15.08.2018
LV15.08.2018
NL15.08.2018
RS15.08.2018
SE15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/12]AL15.08.2018
AT15.08.2018
FI15.08.2018
HR15.08.2018
LT15.08.2018
LV15.08.2018
NL15.08.2018
RS15.08.2018
SE15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/11]AT15.08.2018
FI15.08.2018
HR15.08.2018
LT15.08.2018
NL15.08.2018
RS15.08.2018
SE15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/10]AT15.08.2018
FI15.08.2018
LT15.08.2018
NL15.08.2018
RS15.08.2018
SE15.08.2018
BG15.11.2018
NO15.11.2018
GR16.11.2018
IS15.12.2018
Former [2019/09]FI15.08.2018
LT15.08.2018
NL15.08.2018
NO15.11.2018
IS15.12.2018
Former [2019/08]FI15.08.2018
LT15.08.2018
NO15.11.2018
IS15.12.2018
Former [2019/07]LT15.08.2018
Documents cited:Search[XI]WO9215711  (UNIV MINNESOTA [US]) [X] 1,2 * the whole document * * page 27, line 22 - line 25 * [I] 3-5;
 [XA]EP0953650  (INNOGENETICS NV [BE]) [X] 6,7 * the whole document * * paragraph [0017] * * paragraph [0009] * [A] 4;
 [XI]US2007065860  (HILDEBRAND WILLIAM H [US], et al) [X] 1,2 * paragraph [0026] * * abstract * * paragraph [0035] - paragraph [0037] * [I] 3-5;
 [XA]JP2009261358  (IGAKU SEIBUTSUGAKU KENKYUSHO K) [X] 6,7 * the whole document * [A] 4;
 [A]WO2011030159  (KING S COLLEGE LONDON [GB], et al) [A] 1-7 * p.9, paragraphs 1-5 * * paragraph bridging p.18-19 * * p.32, paragraphs 3-4 * * examples 1-2; tables 1-2 * * claims 1, 4-12, 23-24, 29-30 * * p.5, paragraph 3-p.6, paragraph 2 *;
 [A]WO2012000445  (BGI SHENZHEN CO LTD [CN], et al) [A] 1-7 * the whole document *;
 [AD]WO2013011734  (GENODIVE PHARMA INC [JP], et al) [AD] 1-7 * the whole document *;
 [T]EP2599877  (BGI SHENZHEN CO LTD [CN]) [T] * paragraph [0026] - paragraph [0082] * * abstract * * paragraph [0014] *;
 [XPI]WO2014065410  (GENODIVE PHARMA INC [JP]) [XP] 1,2,5 * page 7; table 1 * [I] 3,4,6,7;
 [T]EP2735617  (GENODIVE PHARMA INC [JP]) [T] * paragraph [0014] - paragraph [0016] * * [0042], [0079], [0103], [0139];; tables 1-4 * * figures 4, 7, 8 * * paragraph [0143] - paragraph [0144] * * claims 1-35 *;
 [E]WO2015047220  (UNIV GEORGETOWN [US]) [E] 1,2,5 * the whole document *;
 [E]WO2015080226  (GENODIVE PHARMA INC [JP]) [E] 1-7 * the whole document *;
 [T]EP3075863  (GENODIVE PHARMA INC [JP]) [T] * paragraph [0016] - paragraph [0018]; examples 2-3 * * claims 1-7 *;
    [ ] - Anonymous, "EM_PAT:A93974", (19991103), URL: http://ibis.internal.epo.org/exam/dbfetch.jsp?id=EM_PAT:A93974, (20161216), XP055329787 [ ] * abstract *
    [ ] - Anonymous, "EM_PAT:FU756955", (20091112), URL: http://ibis.internal.epo.org/exam/dbfetch.jsp?id=EM_PAT:FU756955, (20161216), XP055329777 [ ] * abstract *
 [P]  - "WO 2015080226-A/8: Method and Kit for DNA typing of HLA genes using massive parallel sequencer.", EMBL, (20151110), Database accession no. HZ080360, URL: EBI, XP002765313 [P] * abstract *
    [ ] - Anonymous, "EM_PAT:HZ080360", (20150604), URL: http://ibis.internal.epo.org/exam/dbfetch.jsp?id=EM_PAT:HZ080360, (20161216), XP055329918
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DOI:   http://dx.doi.org/10.1111/j.1399-0039.2009.01345.x
 [A]  - HOLCOMB C L ET AL, "A multi-site study using high-resolution HLA genotyping by next generation sequencing", TISSUE ANTIGENS., DK, (20110308), vol. 77, no. 3, doi:10.1111/j.1399-0039.2010.01606.x, ISSN 0001-2815, pages 206 - 217, XP055329817 [A] 1-7 * abstract * * page 207, column 1, paragraph 2 - paragraph 3 *

DOI:   http://dx.doi.org/10.1111/j.1399-0039.2010.01606.x
 [T]  - OZAKI Y ET AL, "Cost-efficient multiplex PCR for routine genotyping of up to nine classical HLA loci in a single analytical run of multiple samples by next generation sequencing", BMC GENOMICS, BIOMED CENTRAL LTD, LONDON, UK, (20150418), vol. 16, no. 1, doi:10.1186/S12864-015-1514-4, ISSN 1471-2164, page 318, XP021216791 [T] 1-7 * the whole document *

DOI:   http://dx.doi.org/10.1186/s12864-015-1514-4
International search[A]WO0061795  (INNOGENETICS NV [BE], et al);
 [A]WO2005042764  (DYNAL BIOTECH LLC [US], et al);
 [Y]  - SHINGO SUZUKI ET AL., "Jisedai Sequencer o Mochiita HLA Class I Idenshi no Cho Kokaizodo DNA Typing (Super high resolution Single molecule-Sequence Based Typing; SS-SBT) Ho no Kaihatsu", MHC, (2012), vol. 19, no. 1, pages 43 - 53, XP008182619
 [Y]  - YUKI OZAKI ET AL., "Jisedai Sequencer o Mochiita HLA-DRB1 Idenshi no Cho Kokaizodo DNA Typing (Super high resolution Single molecule- Sequence Based Typing; SS-SBT) Ho no Kaihatsu", MHC, (2012), vol. 19, no. 2, pages 211 - 221, XP008182343
 [A]  - MOONSAMY P.V. ET AL., "HIGH THROUGHPUT HLA GENOTYPING USING 454 SEQUENCING AND THE FLUIDIGM ACCESS ARRAY SYSTEM FOR SIMPLIFIED AMPLICON LIBRARY PREPARATION", TISSUE ANTIGENS, (201303), vol. 81, no. 3, pages 141 - 149, XP055127659

DOI:   http://dx.doi.org/10.1111/tan.12071
by applicantJPH0216000
 WO2013011734
    - LIND C. ET AL., HUMAN IMMUNOLOGY, (2010), vol. 71, pages 1033 - 1042
    - SHIINA T. ET AL., TISSUE ANTIGENS, (2012), vol. 80, pages 305 - 316
    - HIDETOSHI INOKO; TAKEHIKO SASAZUKI; TAKEO JUUJI, Transplantation/transfusion Examination, KODAN-SHA SCIENTIFIC, (2004), page 48
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