EP3002588 - USE OF A BIOMARKER FOR DIAGNOSING SCHIZOPHRENIA [Right-click to bookmark this link] | |||
Former [2016/14] | BIOMARKER FOR PSYCHIATRIC AND NEUROLOGICAL DISORDERS | ||
[2021/31] | Status | No opposition filed within time limit Status updated on 18.11.2022 Database last updated on 02.09.2024 | |
Former | The patent has been granted Status updated on 10.12.2021 | ||
Former | Grant of patent is intended Status updated on 29.07.2021 | ||
Former | Examination is in progress Status updated on 18.11.2019 | Most recent event Tooltip | 27.04.2024 | Lapse of the patent in a contracting state New state(s): MK | published on 29.05.2024 [2024/22] | Applicant(s) | For all designated states Ishikawa, Toru 601 Ferizu Minamiosawa 3-6 Shimoyugi, Hachioji-shi Tokyo 192-0372 / JP | [2016/28] |
Former [2016/14] | For all designated states Resvo Inc. 15-5, Omorikita 3-chome Ota-ku Tokyo 143-0016 / JP | Inventor(s) | 01 /
OHNISHI, Arata c/o NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES 4-9-1 Anagawa Inage-ku Chiba-shi Chiba 263-8555 / JP | 02 /
MINAMIMOTO, Takafumi c/o NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES 4-9-1 Anagawa Inage-ku Chiba-shi Chiba 263-8555 / JP | 03 /
SUHARA, Tetsuya c/o NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES 4-9-1 Anagawa Inage-ku Chiba-shi Chiba 263-8555 / JP | [2016/14] | Representative(s) | Maikowski & Ninnemann Patentanwälte Partnerschaft mbB Postfach 15 09 20 10671 Berlin / DE | [2022/02] |
Former [2016/14] | Maikowski & Ninnemann Postfach 15 09 20 10671 Berlin / DE | Application number, filing date | 14797879.5 | 18.03.2014 | [2016/14] | WO2014JP57227 | Priority number, date | JP20130104124 | 16.05.2013 Original published format: JP 2013104124 | [2016/14] | Filing language | JA | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2014185145 | Date: | 20.11.2014 | Language: | JA | [2014/47] | Type: | A1 Application with search report | No.: | EP3002588 | Date: | 06.04.2016 | Language: | EN | [2016/14] | Type: | B1 Patent specification | No.: | EP3002588 | Date: | 12.01.2022 | Language: | EN | [2022/02] | Search report(s) | International search report - published on: | JP | 20.11.2014 | (Supplementary) European search report - dispatched on: | EP | 20.07.2017 | Classification | IPC: | G01N33/53, G01N33/543, C07K16/00, C12Q1/02, C07K16/42, G01N33/68 | [2017/14] | CPC: |
G01N33/6896 (EP,US);
G01N33/6857 (US);
C07K16/42 (EP,US);
G01N33/6863 (US);
G01N33/6869 (US);
G01N33/6893 (US);
G01N2333/525 (US);
G01N2333/5412 (US);
G01N2333/545 (US);
G01N2800/2821 (EP,US);
G01N2800/301 (EP,US);
G01N2800/302 (EP,US);
G01N2800/304 (EP,US)
(-)
|
Former IPC [2016/14] | G01N33/53, G01N33/543, C07K16/00, C12Q1/02 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2016/14] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | VERWENDUNG EINES BIOMARKERS ZUR DIAGNOSE VON SCHIZOPHRENIE | [2021/31] | English: | USE OF A BIOMARKER FOR DIAGNOSING SCHIZOPHRENIA | [2021/31] | French: | UTILISATION D'UN BIOMARQUEUR POUR LE DIAGNOSTIC DE SCHIZOPHRÉNIE. | [2021/31] |
Former [2016/14] | BIOMARKER FÜR PSYCHIATRISCHE UND NEUROLOGISCHE ERKRANKUNGEN | ||
Former [2016/14] | BIOMARKER FOR PSYCHIATRIC AND NEUROLOGICAL DISORDERS | ||
Former [2016/14] | MARQUEUR BIOLOGIQUE POUR TROUBLES PSYCHIATRIQUES ET NEUROLOGIQUES | Entry into regional phase | 10.12.2015 | Translation filed | 10.12.2015 | National basic fee paid | 10.12.2015 | Search fee paid | 10.12.2015 | Designation fee(s) paid | 10.12.2015 | Examination fee paid | Examination procedure | 10.12.2015 | Examination requested [2016/14] | 16.02.2018 | Amendment by applicant (claims and/or description) | 21.11.2019 | Despatch of a communication from the examining division (Time limit: M04) | 23.03.2020 | Reply to a communication from the examining division | 25.06.2021 | Cancellation of oral proceeding that was planned for 02.07.2021 | 02.07.2021 | Date of oral proceedings (cancelled) | 30.07.2021 | Communication of intention to grant the patent | 29.11.2021 | Fee for grant paid | 29.11.2021 | Fee for publishing/printing paid | 29.11.2021 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 21.11.2019 | Opposition(s) | 13.10.2022 | No opposition filed within time limit [2022/51] | Fees paid | Renewal fee | 11.03.2016 | Renewal fee patent year 03 | 16.03.2017 | Renewal fee patent year 04 | 26.03.2018 | Renewal fee patent year 05 | 14.03.2019 | Renewal fee patent year 06 | 16.03.2020 | Renewal fee patent year 07 | 29.03.2021 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 18.03.2014 | AL | 12.01.2022 | AT | 12.01.2022 | CY | 12.01.2022 | CZ | 12.01.2022 | DK | 12.01.2022 | EE | 12.01.2022 | ES | 12.01.2022 | FI | 12.01.2022 | HR | 12.01.2022 | IT | 12.01.2022 | LT | 12.01.2022 | LV | 12.01.2022 | MC | 12.01.2022 | MK | 12.01.2022 | PL | 12.01.2022 | RO | 12.01.2022 | RS | 12.01.2022 | SE | 12.01.2022 | SI | 12.01.2022 | SK | 12.01.2022 | SM | 12.01.2022 | IE | 18.03.2022 | LU | 18.03.2022 | BE | 31.03.2022 | CH | 31.03.2022 | LI | 31.03.2022 | BG | 12.04.2022 | NO | 12.04.2022 | GR | 13.04.2022 | IS | 12.05.2022 | PT | 12.05.2022 | [2024/22] |
Former [2024/20] | HU | 18.03.2014 | |
AL | 12.01.2022 | ||
AT | 12.01.2022 | ||
CY | 12.01.2022 | ||
CZ | 12.01.2022 | ||
DK | 12.01.2022 | ||
EE | 12.01.2022 | ||
ES | 12.01.2022 | ||
FI | 12.01.2022 | ||
HR | 12.01.2022 | ||
IT | 12.01.2022 | ||
LT | 12.01.2022 | ||
LV | 12.01.2022 | ||
MC | 12.01.2022 | ||
PL | 12.01.2022 | ||
RO | 12.01.2022 | ||
RS | 12.01.2022 | ||
SE | 12.01.2022 | ||
SI | 12.01.2022 | ||
SK | 12.01.2022 | ||
SM | 12.01.2022 | ||
IE | 18.03.2022 | ||
LU | 18.03.2022 | ||
BE | 31.03.2022 | ||
CH | 31.03.2022 | ||
LI | 31.03.2022 | ||
BG | 12.04.2022 | ||
NO | 12.04.2022 | ||
GR | 13.04.2022 | ||
IS | 12.05.2022 | ||
PT | 12.05.2022 | ||
Former [2024/18] | HU | 18.03.2014 | |
AL | 12.01.2022 | ||
AT | 12.01.2022 | ||
CZ | 12.01.2022 | ||
DK | 12.01.2022 | ||
EE | 12.01.2022 | ||
ES | 12.01.2022 | ||
FI | 12.01.2022 | ||
HR | 12.01.2022 | ||
IT | 12.01.2022 | ||
LT | 12.01.2022 | ||
LV | 12.01.2022 | ||
MC | 12.01.2022 | ||
PL | 12.01.2022 | ||
RO | 12.01.2022 | ||
RS | 12.01.2022 | ||
SE | 12.01.2022 | ||
SI | 12.01.2022 | ||
SK | 12.01.2022 | ||
SM | 12.01.2022 | ||
IE | 18.03.2022 | ||
LU | 18.03.2022 | ||
BE | 31.03.2022 | ||
CH | 31.03.2022 | ||
LI | 31.03.2022 | ||
BG | 12.04.2022 | ||
NO | 12.04.2022 | ||
GR | 13.04.2022 | ||
IS | 12.05.2022 | ||
PT | 12.05.2022 | ||
Former [2023/35] | AL | 12.01.2022 | |
AT | 12.01.2022 | ||
CZ | 12.01.2022 | ||
DK | 12.01.2022 | ||
EE | 12.01.2022 | ||
ES | 12.01.2022 | ||
FI | 12.01.2022 | ||
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MC | 12.01.2022 | ||
PL | 12.01.2022 | ||
RO | 12.01.2022 | ||
RS | 12.01.2022 | ||
SE | 12.01.2022 | ||
SI | 12.01.2022 | ||
SK | 12.01.2022 | ||
SM | 12.01.2022 | ||
IE | 18.03.2022 | ||
LU | 18.03.2022 | ||
BE | 31.03.2022 | ||
CH | 31.03.2022 | ||
LI | 31.03.2022 | ||
BG | 12.04.2022 | ||
NO | 12.04.2022 | ||
GR | 13.04.2022 | ||
IS | 12.05.2022 | ||
PT | 12.05.2022 | ||
Former [2023/10] | AL | 12.01.2022 | |
AT | 12.01.2022 | ||
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MC | 12.01.2022 | ||
PL | 12.01.2022 | ||
RO | 12.01.2022 | ||
RS | 12.01.2022 | ||
SE | 12.01.2022 | ||
SI | 12.01.2022 | ||
SK | 12.01.2022 | ||
SM | 12.01.2022 | ||
IE | 18.03.2022 | ||
LU | 18.03.2022 | ||
BE | 31.03.2022 | ||
CH | 31.03.2022 | ||
LI | 31.03.2022 | ||
BG | 12.04.2022 | ||
NO | 12.04.2022 | ||
GR | 13.04.2022 | ||
IS | 12.05.2022 | ||
PT | 12.05.2022 | ||
Former [2023/09] | AL | 12.01.2022 | |
AT | 12.01.2022 | ||
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MC | 12.01.2022 | ||
PL | 12.01.2022 | ||
RO | 12.01.2022 | ||
RS | 12.01.2022 | ||
SE | 12.01.2022 | ||
SK | 12.01.2022 | ||
SM | 12.01.2022 | ||
IE | 18.03.2022 | ||
LU | 18.03.2022 | ||
CH | 31.03.2022 | ||
LI | 31.03.2022 | ||
BG | 12.04.2022 | ||
NO | 12.04.2022 | ||
GR | 13.04.2022 | ||
IS | 12.05.2022 | ||
PT | 12.05.2022 | ||
Former [2023/08] | AL | 12.01.2022 | |
AT | 12.01.2022 | ||
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MC | 12.01.2022 | ||
PL | 12.01.2022 | ||
RO | 12.01.2022 | ||
RS | 12.01.2022 | ||
SE | 12.01.2022 | ||
SK | 12.01.2022 | ||
SM | 12.01.2022 | ||
IE | 18.03.2022 | ||
LU | 18.03.2022 | ||
BG | 12.04.2022 | ||
NO | 12.04.2022 | ||
GR | 13.04.2022 | ||
IS | 12.05.2022 | ||
PT | 12.05.2022 | ||
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SM | 12.01.2022 | ||
BG | 12.04.2022 | ||
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SM | 12.01.2022 | ||
BG | 12.04.2022 | ||
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BG | 12.04.2022 | ||
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BG | 12.04.2022 | ||
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BG | 12.04.2022 | ||
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NO | 12.04.2022 | Documents cited: | Search | [A]WO9302190 (WELLCOME FOUND [GB]) [A] 8-11; | [X]WO2004039956 (GENENTECH INC [US], et al) [X] 1-3,6,7 * claim 1; sequence 2197 *; | [X]WO2006089294 (ORIGEN THERAPEUTICS INC [US], et al) [X] 1-3,6,7 * claim 41 *; | [X]WO2010141716 (MAYO FOUNDATION [US], et al) [X] 1-3,6,7 * example 1; sequence 19 *; | [A]WO2012078623 (RIDGE DIAGNOSTICS INC [US], et al) [A] 1-7,12-14 * the whole document *; | [A] - POPOVIC ET AL, "Light chain deposition disease restricted to the brain: the first case report", HUMAN PATHOLOGY, SAUNDERS, PHILADELPHIA, PA, US, (20061212), vol. 38, no. 1, doi:10.1016/J.HUMPATH.2006.07.010, ISSN 0046-8177, pages 179 - 184, XP005820477 [A] 1-7,12-14 DOI: http://dx.doi.org/10.1016/j.humpath.2006.07.010 | [A] - Judith A Brebner ET AL, "Polyclonal free light chains: a biomarker of inflammatory disease or treatment target?", F1000 medicine reports, England, doi:10.3410/M5-4, (20130101), page 4, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564472/pdf/medrep-05-04.pdf, (20170201), XP055346393 [A] 1-7,12-14 * the whole document * DOI: http://dx.doi.org/10.3410/M5-4 | [A] - C. A. HUTCHISON ET AL, "Polyclonal Immunoglobulin Free Light Chains as a PotentialBiomarker of Immune Stimulation and Inflammation", CLINICAL CHEMISTRY., WASHINGTON, DC., (20111001), vol. 57, no. 10, doi:10.1373/clinchem.2011.169433, ISSN 0009-9147, pages 1387 - 1389, XP055346581 [A] 1-7,12-14 * the whole document * DOI: http://dx.doi.org/10.1373/clinchem.2011.169433 | [A] - FAGNART O C ET AL, "Free kappa and lambda light chain levels in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases", JOURNAL OF NEUROIMMUNOLOGY, ELSEVIER SCIENCE PUBLISHERS BV, NL, vol. 19, no. 1-2, doi:10.1016/0165-5728(88)90041-0, ISSN 0165-5728, (19880801), pages 119 - 132, (19880801), XP023694532 [A] 1-7,12-14 * the whole document * DOI: http://dx.doi.org/10.1016/0165-5728(88)90041-0 | [A] - M. D. RICHARD ET AL, "Schizophrenia and the immune system: Pathophysiology, prevention, and treatment", AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY., US, (20120501), vol. 69, no. 9, doi:10.2146/ajhp110271, ISSN 1079-2082, pages 757 - 766, XP055346122 [A] 1-7,12-14 * the whole document * DOI: http://dx.doi.org/10.2146/ajhp110271 | [A] - P. RONCO ET AL, "Immunoglobulin Light (Heavy)-Chain Deposition Disease: From Molecular Medicine to Pathophysiology-Driven Therapy", CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, (20061011), vol. 1, no. 6, doi:10.2215/CJN.01730506, ISSN 1555-9041, pages 1342 - 1350, XP055346359 [A] 1-7,12-14 * the whole document * DOI: http://dx.doi.org/10.2215/CJN.01730506 | [X] - Anonymous, "Freelite(TM) Human Lambda Free Kit For use on the Olympus AU(TM) series For in-vitro diagnostic use Product Code: LK018.AU", The Binding Site Group Ltd., PO Box 11712, Birmingham B14 4ZB, UK, (20091101), pages 1 - 3, URL: http://www.peramed.com/peramed/docs/LK018.AU_5051700006408_EN.pdf, (20170710), XP055389388 [X] 8-11 * the whole document * | [X] - Anonymous, "Freelite(TM) Human Kappa Free kit For use on the Roche cobas c systems For in-vitro diagnostic use Product Code: LK016.CB", The Binding Site Group Ltd., PO Box 11712, Birmingham B14 4ZB, UK, (20091001), pages 1 - 2, URL: http://peramed.com/peramed/docs/LK016.CB_5051700012090_EN.pdf, (20170710), XP055389391 [X] 8-11 * the whole document * | International search | [A]WO2011144934 (CAMBRIDGE ENTPR LTD [GB], et al); | [Y]WO2012078623 (RIDGE DIAGNOSTICS INC [US], et al); | [A]US2012238936 (HYDE RODERICK A [US], et al); | [X] - O.C. 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NARASIMHA RAO ET AL., "SERUM IMMUNOGLOBULINS AND SCHIZOPHRENIA", INDIAN J PSYCHIATRY, (1985), vol. 27, no. 4, pages 325 - 328, XP055295411 | [A] - POPOVIC M ET AL., "Light chain deposition disease restricted to the brain: The first case report", HUM PATHOL, (200701), vol. 38, no. 1, pages 179 - 184, XP005820477 DOI: http://dx.doi.org/10.1016/j.humpath.2006.07.010 | Examination | - AVGUSTIN ET AL, "#2 Increased Th1 and Th2 immune reactivity with relative Th2 dominance in patients with acute exacerbation of schizophrenia and chronic schizophrenia", BRAIN, BEHAVIOR AND IMMUNITY, ACADEMIC PRESS, SAN DIEGO, CA, US, (20050701), vol. 19, no. 4, ISSN 0889-1591, pages e1 - e2 | - BOJANA AVGUSTIN ET AL, "Increased Th1 and Th2 immune reactivity with relative Th2 dominance in patients with acute exacerbation of schizophrenia", BRAIN, BEHAVIOR AND IMMUNITY., US, (20050701), vol. 446, no. 2, ISSN 0889-1591, pages 268 - 274 | by applicant | JP2011506995 | JP2012013415 | - KATZMANN JA; CLARK RJ; ABRAHAM RS; BRYANT S; LYMP JF; BRADWELL AR; KYLE RA., CLIN CHEM., (200209), vol. 48, no. 9, pages 1437 - 1444 | - TSIRAKIS G; PAPPA CA; KAPAROU M; KATSOMITROU V; HATZIVASILI A; ALEGAKIS T; XEKALOU A; STATHOPOULOS EN; ALEXANDRAKIS MG, EUR J HISTOCHEM, (2011), vol. 55, no. 3, page E21 | - KUKU I; BAYRAKTAR MR; KAYA E; ERKURT MA; BAYRAKTAR N; CIKIM K; AYDO GDU I., MEDIATORS INFLAMM, (20050814), pages 171 - 174 | - LIMIN SHI ET AL., J. 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