| EP3062780 - ACTIVATORS OR STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR USE IN TREATING CHRONIC FATIGUE SYNDROME [Right-click to bookmark this link] | Status | The application has been refused Status updated on 19.09.2018 Database last updated on 28.02.2026 | |
| Former | Examination is in progress Status updated on 04.08.2017 | Most recent event Tooltip | 05.01.2019 | New entry: Additional fee for renewal fee: despatch of communication + time limit | Applicant(s) | For all designated states Bergen Teknologioverføring AS Thormøhlensgate 51 5006 Bergen / NO | [2016/36] | Inventor(s) | 01 /
FLUGE, Öystein Torvbakken 5 N-5122 Morvik / NO | 02 /
MELLA, Olav Olsvikveien 143 N-5184 Olsvik / NO | [2016/36] | Representative(s) | Kröncke, Rolf Gramm, Lins & Partner Patent- und Rechtsanwälte PartGmbB Freundallee 13 a 30173 Hannover / DE | [2016/36] | Application number, filing date | 14799685.4 | 03.11.2014 | [2016/36] | WO2014EP73538 | Priority number, date | US201361898638P | 01.11.2013 Original published format: US 201361898638 P | [2016/36] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2015063287 | Date: | 07.05.2015 | Language: | EN | [2015/18] | Type: | A1 Application with search report | No.: | EP3062780 | Date: | 07.09.2016 | Language: | EN | The application published by WIPO in one of the EPO official languages on 07.05.2015 takes the place of the publication of the European patent application. | [2016/36] | Search report(s) | International search report - published on: | EP | 07.05.2015 | Classification | IPC: | A61K31/00, A61K31/195, A61K31/506, A61K31/519, C07K16/28, A61P43/00 | [2016/36] | CPC: |
A61K31/506 (EP,US);
A61K31/00 (EP,US);
A61K31/195 (EP,US);
A61K31/197 (US);
A61K31/519 (EP,US);
A61K39/3955 (US);
| C-Set: |
A61K31/195, A61K2300/00 (EP,US);
A61K31/506, A61K2300/00 (US,EP);
A61K31/519, A61K2300/00 (US,EP)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2016/36] | Title | German: | AKTIVATOREN ODER STIMULATOREN LÖSLICHER GUANYLATCYCLASE ZUR VERWENDUNG BEI DER BEHANDLUNG DES CHRONISCHEN ERMÜDUNGSSYNDROMS | [2016/36] | English: | ACTIVATORS OR STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR USE IN TREATING CHRONIC FATIGUE SYNDROME | [2016/36] | French: | ACTIVATEURS OU STIMULATEURS DE GUANYLATE CYCLASE SOLUBLE DESTINÉS À ÊTRE UTILISÉS POUR TRAITER UN SYNDROME DE FATIGUE CHRONIQUE | [2016/36] | Entry into regional phase | 11.05.2016 | National basic fee paid | 11.05.2016 | Designation fee(s) paid | 11.05.2016 | Examination fee paid | Examination procedure | 11.05.2016 | Amendment by applicant (claims and/or description) | 11.05.2016 | Examination requested [2016/36] | 04.08.2017 | Despatch of a communication from the examining division (Time limit: M06) | 08.01.2018 | Reply to a communication from the examining division | 11.09.2018 | Cancellation of oral proceeding that was planned for 12.11.2018 | 20.09.2018 | Despatch of communication that the application is refused, reason: substantive examination [2019/06] | 30.09.2018 | Application refused, date of legal effect [2019/06] | 12.11.2018 | Date of oral proceedings (cancelled) | Fees paid | Renewal fee | 04.11.2016 | Renewal fee patent year 03 | 06.11.2017 | Renewal fee patent year 04 | Penalty fee | Additional fee for renewal fee | 30.11.2018 | 05   M06   Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X] PALL M L: "Cobalamin used in chronic fatigue syndrome therapy is a nitric oxide scavenger", JOURNAL OF CHRONIC FATIGUE SYNDROME 2001 US, vol. 8, no. 2, 2001, pages 39 - 44, XP008173751, ISSN: 1057-3321 [X] 1,12-14,19,20 * abstract * * page 40, paragraph 1 * DOI: http://dx.doi.org/10.1300/J092v08n02_04 | [A] I. SHARINA ET AL: "Cobinamides Are Novel Coactivators of Nitric Oxide Receptor That Target Soluble Guanylyl Cyclase Catalytic Domain", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 340, no. 3, 1 March 2012 (2012-03-01), pages 723 - 732, XP055156951, ISSN: 0022-3565, DOI: 10.1124/jpet.111.186957 [A] 1,12-14,19,20 * page 726, column 2, paragraph 1 * * figure 2B * DOI: http://dx.doi.org/10.1124/jpet.111.186957 | by applicant | NACUL ET AL., BMC MED, vol. 9, 2011, pages 1 | ALBRIGHT ET AL., BMC NEUROL, vol. 11, 2011, pages 62 | CAR-RUTHERS B.M., J. CHRONIC FATIGUE SYNDR, vol. 11, 2003, pages 7 - 36 | KAUSHIK N. ET AL., J. CLIN PATHOL, vol. 58, 2005, pages 826 - 32 | VOLLMER-CONNA U. ET AL., CLIN INFECT DIS, vol. 45, 2007, pages 732 - 5 | OGAVA M. ET AL., EUR J OF CLIN INVEST, vol. 28, 1998, pages 937 - 943 | MIHAYLOVA I. ET AL., NEURO ENDOCRINOL LETT, vol. 28, 2007, pages 477 - 83 | BRENU ET AL., J TRANS MED, vol. 10, 2012, pages 88 | STAINES DR., MED HYPOTHESES, vol. 64, 2005, pages 539 - 42 | FLUGE O.; MELLA O., BMC NEUROL., vol. 9, 2009, pages 28 | FLUGE O. ET AL., PLOS, vol. 6, 2011, pages E26359 | CHANG C.M., CANCER, vol. 118, 2012, pages 5929 - 36 | NOSSAMAN B. ET AL., CRITICAL CARE RESEARCH AND PRACTICE, 2012 | GHOFRANI ET AL., NEJM, vol. 369, 2013, pages 4 | ERDMANN ET AL., EUR J HEART, vol. 34, 2013, pages 1 | CLARK ET AL., PROC. NATL. ACAD. SD. (USA, vol. 82, 1985, pages 1766 | "Remington's Pharmaceutical Sciences", 1980 |