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Extract from the Register of European Patents

EP About this file: EP3004154

EP3004154 - IL-1beta-IL-1Ra CHIMERA AND METHODS OF USING THE SAME [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  11.10.2019
Database last updated on 19.07.2024
FormerExamination is in progress
Status updated on  02.03.2018
Most recent event   Tooltip11.10.2019Application deemed to be withdrawnpublished on 13.11.2019  [2019/46]
Applicant(s)For all designated states
Ben Gurion University of The Negev Research and Development Authority
P.O.B. 653
84105 Beer Sheva / IL
For all designated states
The Regents of the University of Colorado, a body corporate
1800 Grant Street, 8th Floor
Denver, CO 80203 / US
[2016/15]
Inventor(s)01 / LEWIS, Eli
29 Max Bourne Street
84835 Beer Sheva / IL
02 / RIDER, Peleg
Tse'ela St. 14
8496500 Omer / IL
03 / DINARELLO, Charles A.
333 15th STreet
Boulder, Colorado 80302 / US
 [2016/15]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[N/P]
Former [2016/15]Boult Wade Tennant
Verulam Gardens
70 Gray's Inn Road
London WC1X 8BT / GB
Application number, filing date14807762.105.06.2014
[2016/15]
WO2014IL50508
Priority number, dateUS201361831318P05.06.2013         Original published format: US 201361831318 P
[2016/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2014195953
Date:11.12.2014
Language:EN
[2014/50]
Type: A1 Application with search report 
No.:EP3004154
Date:13.04.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 11.12.2014 takes the place of the publication of the European patent application.
[2016/15]
Search report(s)International search report - published on:IL11.12.2014
(Supplementary) European search report - dispatched on:EP05.12.2016
ClassificationIPC:C07K14/545, A61P29/00, C07K19/00, C12N15/62
[2016/15]
CPC:
A61K38/2006 (EP,US); A61K38/1709 (EP,US); A61P29/00 (EP);
C07K14/47 (US); C07K14/545 (EP,US); C07K14/7155 (EP,US);
C07K2319/00 (EP,US); C07K2319/21 (EP,US); C07K2319/50 (EP,US);
C07K2319/74 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/15]
TitleGerman:IL-1-BETTA-IL-1RA-CHIMÄRE UND VERFAHREN ZUR VERWENDUNG DAVON[2016/15]
English:IL-1beta-IL-1Ra CHIMERA AND METHODS OF USING THE SAME[2016/15]
French:CHIMÈRES IL-1BÊTA-IL-1RA ET LEURS PROCÉDÉS D'UTILISATION[2016/15]
Entry into regional phase01.12.2015National basic fee paid 
01.12.2015Search fee paid 
01.12.2015Designation fee(s) paid 
01.12.2015Examination fee paid 
Examination procedure01.12.2015Examination requested  [2016/15]
29.06.2017Amendment by applicant (claims and/or description)
28.02.2018Despatch of a communication from the examining division (Time limit: M04)
06.07.2018Reply to a communication from the examining division
16.01.2019Despatch of a communication from the examining division (Time limit: M04)
28.05.2019Application deemed to be withdrawn, date of legal effect  [2019/46]
27.06.2019Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2019/46]
Fees paidRenewal fee
28.06.2016Renewal fee patent year 03
26.06.2017Renewal fee patent year 04
11.06.2018Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.06.201906   M06   Not yet paid
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Documents cited:Search[A]WO2011123683  (UNIV ROCHESTER [US], et al) [A] 1-15 * claims 1-44 *;
 [XI]WO2012016203  (ELEVEN BIOTHERAPEUTICS INC [US], et al) [X] 1,3,7,8,10-15 * claims 1-70; sequences 17-24 * [I] 2,4-6,9;
 [XI]  - CHARLES A. DINARELLO ET AL, "Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases", NATURE REVIEWS DRUG DISCOVERY, (20120801), vol. 11, no. 8, doi:10.1038/nrd3800, ISSN 1474-1776, pages 633 - 652, XP055051238 [X] 1,3,7,12-15 * pages 640, 648 * [I] 2,4-6,8-11

DOI:   http://dx.doi.org/10.1038/nrd3800
 [A]  - IRMLER M ET AL, "Granzyme A is an interleukin 1 beta-converting enzyme", THE JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIVERSITY PRESS, US, (19950501), vol. 181, no. 5, doi:10.1084/JEM.181.5.1917, ISSN 0022-1007, pages 1917 - 1922, XP002671415 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1084/jem.181.5.1917
 [A]  - MOHAMMED F. SHAMJI ET AL, "Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: Sustained release of a local antiinflammatory therapeutic", ARTHRITIS & RHEUMATISM, US, (20071101), vol. 56, no. 11, doi:10.1002/art.22952, ISSN 0004-3591, pages 3650 - 3661, XP055322297 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1002/art.22952
 [T]  - PELEG RIDER ET AL, "IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation", THE JOURNAL OF IMMUNOLOGY, US, (20150708), vol. 195, no. 4, doi:10.4049/jimmunol.1501168, ISSN 0022-1767, pages 1705 - 1712, XP055322288 [T] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.4049/jimmunol.1501168
International search[A]WO03068934  (RUTTER WILLIAM J [US]) [A] 1-27 * The whole document *;
 [A]WO2009077755  (QUEEN MARY & WESTFIELD COLLEGE [GB], et al) [A] 1-27* The whole document *;
 [A]WO2011028344  (AMUNIX OPERATING INC [US], et al) [A] 1-27 * The whole document *;
 [A]  - DINARELLO C.A., "Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.", Int Rev Immunol., vol. 16, no. 5-6, (19980000), pages 457 - 499., URL: http://informahealthcare.com/doi/abs/10.3109/08830189809043005, (20140910), XP001059110 [A] 1-27 * The whole document, especially page 464, second paragraph, FIG 1, page 479, first paragraph *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.