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Extract from the Register of European Patents

EP About this file: EP3090059

EP3090059 - LUNG CANCER DETERMINATIONS USING MIRNA RATIOS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.04.2019
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  04.05.2018
FormerGrant of patent is intended
Status updated on  08.08.2017
Most recent event   Tooltip03.07.2020Lapse of the patent in a contracting state
New state(s): HU, MK
published on 05.08.2020  [2020/32]
Applicant(s)For all designated states
Sozzi, Gabriella
Via Vivaio 4
20122 Milan / IT
For all designated states
Boeri, Mattia
Via Banfi 3
20122 Milan / IT
For all designated states
Pastorino, Ugo
Via S. Francesco d'Assisi 15
20123 Milan / IT
[2019/15]
Former [2017/36]For all designated states
Biomirna Holdings Ltd.
24 Farney Park
Sandymount
Dublin 4 / IE
Former [2016/45]For all designated states
Biomirna Holdings Ltd.
24 Farney park
Sandymount
Dublin 4 / IE
Inventor(s)01 / see applicant
...
 [2019/15]
Former [2017/17]01 / SOZZI, Gabriella
Via Vivaio 4
I-20122 Milan / IT
02 / BOERI, Mattia
Via Banfi 3
I-20122 Milan / IT
03 / PASTORINO, Ugo
Via S. Francesco d'Assisi 15
I-20123 Milan / IT
Former [2016/45]01 / SOZZI, Gabriella
Via Banfi
I-20122 Milan / IT
02 / BOERI, Mattia
Via Banfi
I-20122 Milan / IT
03 / PASTORINO, Ugo
Via S. Francesco d'Assisi 15
I-20123 Milan / IT
Representative(s)Cooley (UK) LLP
22 Bishopsgate
London EC2N 4BQ / GB
[N/P]
Former [2016/45]Cooley (UK) LLP
Dashwood
69 Old Broad Street
London EC2M 1QS / GB
Application number, filing date14827245.331.12.2014
[2016/45]
WO2014EP79499
Priority number, dateUS201461923758P05.01.2014         Original published format: US 201461923758 P
US201461926323P12.01.2014         Original published format: US 201461926323 P
[2016/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015101653
Date:09.07.2015
Language:EN
[2015/27]
Type: A1 Application with search report 
No.:EP3090059
Date:09.11.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 09.07.2015 takes the place of the publication of the European patent application.
[2016/45]
Type: B1 Patent specification 
No.:EP3090059
Date:06.06.2018
Language:EN
[2018/23]
Search report(s)International search report - published on:EP09.07.2015
ClassificationIPC:C12Q1/68
[2016/45]
CPC:
C12Q1/6886 (EP,IL,US); C12Q1/6813 (IL); C12Q2600/118 (EP,IL,US);
C12Q2600/158 (EP,IL,US); C12Q2600/16 (EP,IL,US); C12Q2600/166 (EP,IL,US);
C12Q2600/178 (EP,IL,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/45]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:MICRO-RNA QUOTIENTEN ZUR BESTIMMUNG VON LUNGENKREBS[2017/29]
English:LUNG CANCER DETERMINATIONS USING MIRNA RATIOS[2016/45]
French:DIAGNOSTIC DU CANCER DU POUMON EN UTILISANT LE RAPPORT MIARN[2017/29]
Former [2016/45]LUNGENKREBSBESTIMMUNGEN MITTELS MIRNA-VERHÄLTNISSEN
Former [2016/45]DÉTERMINATIONS DE CANCER DU POUMON AU MOYEN DE RAPPORTS DE MIARN
Entry into regional phase26.07.2016National basic fee paid 
26.07.2016Designation fee(s) paid 
26.07.2016Examination fee paid 
Examination procedure26.07.2016Examination requested  [2016/45]
22.02.2017Amendment by applicant (claims and/or description)
31.03.2017Despatch of communication of loss of particular rights: Claims {1}
09.08.2017Communication of intention to grant the patent
18.12.2017Fee for grant paid
18.12.2017Fee for publishing/printing paid
18.12.2017Receipt of the translation of the claim(s)
Divisional application(s)EP18175641.2  / EP3425066
Opposition(s)07.03.2019No opposition filed within time limit [2019/20]
Request for further processing for:Loss of rights: Claims
07.04.2017Request for further processing filed
07.04.2017Full payment received (date of receipt of payment)
Request granted
19.04.2017Decision despatched
Fees paidRenewal fee
29.12.2016Renewal fee patent year 03
26.04.2018Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.12.201704   M06   Fee paid on   26.04.2018
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU31.12.2014
AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
MK06.06.2018
NL06.06.2018
PL06.06.2018
PT06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
TR06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
BE31.12.2018
LU31.12.2018
MT31.12.2018
[2020/31]
Former [2020/30]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
PT06.06.2018
RO06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
TR06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
BE31.12.2018
LU31.12.2018
MT31.12.2018
Former [2020/28]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
PT06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
TR06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
BE31.12.2018
LU31.12.2018
MT31.12.2018
Former [2020/16]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
TR06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
BE31.12.2018
LU31.12.2018
MT31.12.2018
Former [2020/08]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
BE31.12.2018
LU31.12.2018
MT31.12.2018
Former [2019/51]AL06.06.2018
AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
BE31.12.2018
LU31.12.2018
Former [2019/40]AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
MC06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
LU31.12.2018
Former [2019/39]AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
LU31.12.2018
Former [2019/26]AT06.06.2018
CY06.06.2018
CZ06.06.2018
DK06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SI06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/11]AT06.06.2018
CY06.06.2018
CZ06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SK06.06.2018
SM06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/10]AT06.06.2018
CY06.06.2018
CZ06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
PL06.06.2018
RS06.06.2018
SE06.06.2018
SK06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/09]CY06.06.2018
EE06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/08]CY06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
IS06.10.2018
Former [2019/03]CY06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
NL06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
Former [2018/52]CY06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
GR07.09.2018
Former [2018/51]CY06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
LV06.06.2018
RS06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
Former [2018/50]CY06.06.2018
FI06.06.2018
HR06.06.2018
LT06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
Former [2018/49]CY06.06.2018
FI06.06.2018
LT06.06.2018
SE06.06.2018
BG06.09.2018
NO06.09.2018
Former [2018/47]FI06.06.2018
LT06.06.2018
NO06.09.2018
Cited inInternational search[A]WO2009070653  (UNIV OHIO STATE RES FOUND [US], et al) [A] 1-43 * the whole document *;
 [A]WO2011053257  (AGENCY SCIENCE TECH & RES [SG], et al) [A] 1-43 * the whole document *;
 [I]WO2012107841  (BIOMIRNA HOLDINGS LTD [IE], et al) [I] 1-43 * the whole document *;
 [Y]  - M. BOERI ET AL, "MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20110301), vol. 108, no. 9, doi:10.1073/pnas.1100048108, ISSN 0027-8424, pages 3713 - 3718, XP055044109 [Y] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.1100048108
 [Y]  - QIAN S ET AL, "MicroRNA expression profile of bronchioalveolar stem cells from mouse lung", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 377, no. 2, doi:10.1016/J.BBRC.2008.10.052, ISSN 0006-291X, (20081212), pages 668 - 673, (20081021), XP025646136 [Y] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2008.10.052
 [A]  - BOERI M ET AL, "Role of MicroRNAs in lung cancer: MicroRNA signatures in cancer prognosis", CANCER JOURNAL (UNITED STATES) 2012 LIPPINCOTT WILLIAMS AND WILKINS USA, (201205), vol. 18, no. 3, ISSN 1528-9117, pages 268 - 274, XP008175873 [A] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1097/PPO.0b013e318258b743
 [A]  - JI QI ET AL, "MicroRNAs and lung cancers: from pathogenesis to clinical implications", FRONTIERS OF MEDICINE, SP HIGHER EDUCATION PRESS, HEIDELBERG, (20120418), vol. 6, no. 2, doi:10.1007/S11684-012-0188-4, ISSN 2095-0225, pages 134 - 155, XP035065369 [A] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1007/s11684-012-0188-4
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