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Extract from the Register of European Patents

EP About this file: EP3029069

EP3029069 - ANTI-HUMAN CD26 MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.08.2020
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  30.08.2019
FormerGrant of patent is intended
Status updated on  29.04.2019
FormerExamination is in progress
Status updated on  01.06.2018
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK
published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Juntendo Educational Foundation
2-1-1, Hongo
Bunkyo-ku
Tokyo 113-8421 / JP
[2016/23]
Inventor(s)01 / MORIMOTO, Chikao
c/o Juntendo University
2-1-1 Hongo
Bunkyo-ku
Tokyo 113-8421 / JP
02 / HATANO, Ryo
c/o Juntendo University
2-1-1 Hongo
Bunkyo-ku
Tokyo 113-8421 / JP
03 / YAMADA, Taketo
2-1-26 Takaido Higashi
Suginami-ku
Tokyo 168-0072 / JP
04 / OHNUMA, Kei
c/o Juntendo University
2-1-1 Hongo
Bunkyo-ku
Tokyo 113-8421 / JP
 [2016/23]
Representative(s)Blodig, Wolfgang
Wächtershäuser & Hartz
Patentanwaltspartnerschaft mbB
Weinstrasse 8
80333 München / DE
[2016/23]
Application number, filing date14831681.330.07.2014
[2016/23]
WO2014JP70084
Priority number, dateJP2013015853331.07.2013         Original published format: JP 2013158533
[2016/23]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015016267
Date:05.02.2015
Language:JA
[2015/05]
Type: A1 Application with search report 
No.:EP3029069
Date:08.06.2016
Language:EN
[2016/23]
Type: B1 Patent specification 
No.:EP3029069
Date:02.10.2019
Language:EN
[2019/40]
Search report(s)International search report - published on:JP05.02.2015
(Supplementary) European search report - dispatched on:EP05.12.2016
ClassificationIPC:C07K16/28, C07K16/40, C12N5/10, G01N33/53, G01N33/574, G01N33/577, C12N15/09, C12P21/08, G01N33/569, G01N33/564
[2017/01]
CPC:
C07K16/40 (EP,US); C07K16/2896 (EP,US); C12N5/163 (EP,US);
G01N33/564 (EP,US); G01N33/56972 (EP,US); G01N33/56983 (EP,US);
G01N33/573 (US); G01N33/574 (EP,US); G01N33/57419 (EP,US);
G01N33/57423 (EP,US); G01N33/57434 (EP,US); G01N33/577 (EP,US);
G01N33/6893 (EP,US); A61K2039/505 (US); C07K2317/24 (EP,US);
C07K2317/76 (US); G01N2333/70596 (EP,US); G01N2333/948 (US);
G01N2500/00 (EP,US); G01N2800/042 (EP,US) (-)
Former IPC [2016/23]C07K16/28, C07K16/40, C12N5/10, G01N33/53, G01N33/574, G01N33/577, C12N15/09, C12P21/08
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/23]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:MONOKLONALER ANTI-HUMAN-CD26-ANTIKÖRPER ODER ANTIGENBINDENDES FRAGMENT DAVON[2016/23]
English:ANTI-HUMAN CD26 MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF[2016/23]
French:ANTICORPS MONOCLONAL ANTI-CD26 HUMAIN, OU SON FRAGMENT DE LIAISON À L'ANTIGÈNE[2016/23]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase11.02.2016Translation filed 
11.02.2016National basic fee paid 
11.02.2016Search fee paid 
11.02.2016Designation fee(s) paid 
11.02.2016Examination fee paid 
Examination procedure11.02.2016Examination requested  [2016/23]
06.06.2017Amendment by applicant (claims and/or description)
05.06.2018Despatch of a communication from the examining division (Time limit: M04)
01.08.2018Reply to a communication from the examining division
30.04.2019Communication of intention to grant the patent
20.08.2019Fee for grant paid
20.08.2019Fee for publishing/printing paid
20.08.2019Receipt of the translation of the claim(s)
Opposition(s)03.07.2020No opposition filed within time limit [2020/37]
Fees paidRenewal fee
01.08.2016Renewal fee patent year 03
31.07.2017Renewal fee patent year 04
30.07.2018Renewal fee patent year 05
31.07.2019Renewal fee patent year 06
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Lapses during opposition  TooltipHU30.07.2014
AL02.10.2019
AT02.10.2019
CY02.10.2019
CZ02.10.2019
DK02.10.2019
EE02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
IT02.10.2019
LT02.10.2019
LV02.10.2019
MC02.10.2019
MK02.10.2019
MT02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
SI02.10.2019
SK02.10.2019
SM02.10.2019
TR02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
IS02.02.2020
PT03.02.2020
[2022/32]
Former [2022/27]HU30.07.2014
AL02.10.2019
AT02.10.2019
CY02.10.2019
CZ02.10.2019
DK02.10.2019
EE02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
IT02.10.2019
LT02.10.2019
LV02.10.2019
MC02.10.2019
MT02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
SI02.10.2019
SK02.10.2019
SM02.10.2019
TR02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
IS02.02.2020
PT03.02.2020
Former [2021/15]AL02.10.2019
AT02.10.2019
CZ02.10.2019
DK02.10.2019
EE02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
IT02.10.2019
LT02.10.2019
LV02.10.2019
MC02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
SI02.10.2019
SK02.10.2019
SM02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
IS02.02.2020
PT03.02.2020
Former [2020/51]AL02.10.2019
AT02.10.2019
CZ02.10.2019
DK02.10.2019
EE02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
IT02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
SI02.10.2019
SK02.10.2019
SM02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
IS02.02.2020
PT03.02.2020
Former [2020/38]AL02.10.2019
AT02.10.2019
CZ02.10.2019
DK02.10.2019
EE02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
IT02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
SK02.10.2019
SM02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
IS02.02.2020
PT03.02.2020
Former [2020/37]AL02.10.2019
AT02.10.2019
CZ02.10.2019
DK02.10.2019
EE02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
SK02.10.2019
SM02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
IS02.02.2020
PT03.02.2020
Former [2020/36]AL02.10.2019
AT02.10.2019
CZ02.10.2019
DK02.10.2019
EE02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
IS02.02.2020
PT03.02.2020
Former [2020/35]AL02.10.2019
AT02.10.2019
CZ02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
RO02.10.2019
RS02.10.2019
SE02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
PT03.02.2020
IS24.02.2020
Former [2020/32]AL02.10.2019
AT02.10.2019
CZ02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
RS02.10.2019
SE02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
PT03.02.2020
IS24.02.2020
Former [2020/25]AT02.10.2019
CZ02.10.2019
ES02.10.2019
FI02.10.2019
HR02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
RS02.10.2019
SE02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
PT03.02.2020
IS24.02.2020
Former [2020/24]AT02.10.2019
ES02.10.2019
FI02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
SE02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
PT03.02.2020
IS24.02.2020
Former [2020/23]AT02.10.2019
ES02.10.2019
FI02.10.2019
LT02.10.2019
LV02.10.2019
NL02.10.2019
PL02.10.2019
SE02.10.2019
BG02.01.2020
NO02.01.2020
GR03.01.2020
PT03.02.2020
Former [2020/22]FI02.10.2019
LT02.10.2019
NL02.10.2019
SE02.10.2019
BG02.01.2020
NO02.01.2020
PT03.02.2020
Former [2020/21]NL02.10.2019
NO02.01.2020
Former [2020/20]NL02.10.2019
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DOI:   http://dx.doi.org/10.1186/1746-1596-9-30
 [Y]  - VISHWA AMATYA, "Overexpression of CD26/DPPIV in mesothelioma tissue and mesothelioma cell lines", ONCOLOGY REPORTS, (20110905), vol. 26, doi:10.3892/or.2011.1449, ISSN 1021-335X, pages 1369 - 1375, XP055322123 [Y] 1-15 * abstract *

DOI:   http://dx.doi.org/10.3892/or.2011.1449
 [Y]  - OORD VAN DEN J J, "EXPRESSION OF CD26/DIPEPTIDYL-PEPTIDASE IV IN BENIGN AND MALIGNANT PIGMENT-CELL LESIONS OF THE SKIN", BRITISH JOURNAL OF DERMATOLOGY, OXFORD : WILEY-BLACKWELL, UK, (19980401), vol. 138, doi:10.1046/J.1365-2133.1998.02171.X, ISSN 0007-0963, pages 615 - 621, XP002944502 [Y] 1-15 * abstract; p. 615 *

DOI:   http://dx.doi.org/10.1046/j.1365-2133.1998.02171.x
International search[Y]JP2009502139  (Y'S THERAPEUTICS, CO., LTD.);
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 [Y]  - HUHN J. ET AL., "The Adenosine Deaminase-Binding Region Is Distinct from Major Anti- CD 26 mAb Epitopes on the Human Dipeptidyl Peptidase IV, (CD 26) Molecule", CELLULAR IMMUNOLOGY, (1999), vol. 192, pages 33 - 40, XP055313948
 [Y]  - ABBOTT C. A. ET AL., "Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted propeller domain", EUR. J. BIOCHEM, (1999), vol. 266, pages 798 - 810, XP055313950

DOI:   http://dx.doi.org/10.1046/j.1432-1327.1999.00902.x
 [Y]  - ULMER A. J. ET AL., "CD 26 Antigen is a Surface Dipeptidyl Peptidase IV (DPPIV) as Characterized by Monoclonal Antibodies Clone TII-19-4-7 and 4EL1C7", SCAND. J. IMMUNOL., (1990), vol. 31, pages 429 - 435, XP001048107
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DOI:   http://dx.doi.org/10.1016/j.it.2008.02.010
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DOI:   http://dx.doi.org/10.1007/s10165-005-0452-4
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    - HAVRE PA; ABE M; URASAKI Y; OHNUMA K; MORIMOTO C; DANG NH, "The role of CD26/dipeptidyl peptidase IV in cancer", FRONT BIOSCI, (2008), vol. 13, pages 1634 - 1645
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