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Extract from the Register of European Patents

EP About this file: EP3054944

EP3054944 - FACTOR XIA INHIBITORS [Right-click to bookmark this link]
Former [2016/33]FACTOR XIa INHIBITORS
[2019/07]
StatusNo opposition filed within time limit
Status updated on  09.10.2020
Database last updated on 29.10.2024
FormerThe patent has been granted
Status updated on  01.11.2019
FormerGrant of patent is intended
Status updated on  02.07.2019
FormerExamination is in progress
Status updated on  12.06.2019
FormerGrant of patent is intended
Status updated on  05.02.2019
FormerExamination is in progress
Status updated on  23.02.2018
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Merck Sharp & Dohme Corp.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
[2016/33]
Inventor(s)01 / SHAO, Ning
65 Pine Lane
Watchung, NJ 07069 / US
02 / EDMONDSON, Scott, D.
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
03 / NEELAMKAVIL, Santhosh
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
04 / GUO, Zhuyan
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
05 / MERTZ, Eric
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
06 / ZANG, Yi
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
07 / HE, Jiafang
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
 [2019/49]
Former [2016/33]01 / SHAO, Ning
65 Pine Lane
Watchung, NJ 07069 / US
02 / EDMONDSON, Scott D.
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
03 / NEELAMKAVIL, Santhosh
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
04 / GUO, Zhuyan
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
05 / MERTZ, Eric
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
06 / ZANG, Yi
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
07 / HE, Jiafang
2000 Galloping Hill Road
Kenilworth, NJ 07033 / US
Representative(s)Jaap, David Robert
Merck Sharp & Dohme Corp.
120 Moorgate
London, EC2M 6UR / GB
[N/P]
Former [2019/49]Jaap, David Robert
MSD
Hertford Road
Hoddesdon, Herts EN11 9BU / GB
Former [2016/33]Jaap, David Robert
MSD Hertford Road
Hoddesdon, Herts EN11 9BU / GB
Application number, filing date14851664.406.10.2014
[2016/33]
WO2014US59213
Priority number, dateUS201361887699P07.10.2013         Original published format: US 201361887699 P
[2016/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015054087
Date:16.04.2015
Language:EN
[2015/15]
Type: A1 Application with search report 
No.:EP3054944
Date:17.08.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 16.04.2015 takes the place of the publication of the European patent application.
[2016/33]
Type: B1 Patent specification 
No.:EP3054944
Date:04.12.2019
Language:EN
[2019/49]
Search report(s)International search report - published on:US16.04.2015
(Supplementary) European search report - dispatched on:EP20.02.2017
ClassificationIPC:A61K31/397, A61K31/7088, C07D413/14, C07D401/14, C07D401/10
[2017/12]
CPC:
C07D401/14 (EP,US); C07C269/06 (US); C07D401/04 (EP,US);
C07D401/10 (EP,US); C07D413/14 (EP,US)
Former IPC [2016/33]A61K31/397, A61K31/7088, C07D413/14
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/33]
Extension statesBA09.05.2016
ME09.05.2016
TitleGerman:FAKTOR-XIA-HEMMER[2016/33]
English:FACTOR XIA INHIBITORS[2019/07]
French:INHIBITORS DU FACTEUR XIA[2016/33]
Former [2016/33]FACTOR XIa INHIBITORS
Entry into regional phase09.05.2016National basic fee paid 
09.05.2016Search fee paid 
09.05.2016Designation fee(s) paid 
09.05.2016Examination fee paid 
Examination procedure09.05.2016Examination requested  [2016/33]
19.09.2017Amendment by applicant (claims and/or description)
23.02.2018Despatch of a communication from the examining division (Time limit: M06)
05.09.2018Reply to a communication from the examining division
06.02.2019Communication of intention to grant the patent
11.06.2019Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
03.07.2019Communication of intention to grant the patent
24.10.2019Fee for grant paid
24.10.2019Fee for publishing/printing paid
24.10.2019Receipt of the translation of the claim(s)
Opposition(s)07.09.2020No opposition filed within time limit [2020/46]
Fees paidRenewal fee
07.10.2016Renewal fee patent year 03
10.10.2017Renewal fee patent year 04
08.10.2018Renewal fee patent year 05
11.10.2019Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU06.10.2014
AL04.12.2019
AT04.12.2019
CY04.12.2019
CZ04.12.2019
DK04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
IT04.12.2019
LT04.12.2019
LV04.12.2019
MC04.12.2019
MK04.12.2019
MT04.12.2019
NL04.12.2019
PL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SI04.12.2019
SK04.12.2019
SM04.12.2019
TR04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
IS04.04.2020
PT29.04.2020
[2022/32]
Former [2022/27]HU06.10.2014
AL04.12.2019
AT04.12.2019
CY04.12.2019
CZ04.12.2019
DK04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
IT04.12.2019
LT04.12.2019
LV04.12.2019
MC04.12.2019
MT04.12.2019
NL04.12.2019
PL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SI04.12.2019
SK04.12.2019
SM04.12.2019
TR04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
IS04.04.2020
PT29.04.2020
Former [2021/31]AL04.12.2019
AT04.12.2019
CZ04.12.2019
DK04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
IT04.12.2019
LT04.12.2019
LV04.12.2019
MC04.12.2019
NL04.12.2019
PL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SI04.12.2019
SK04.12.2019
SM04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
IS04.04.2020
PT29.04.2020
Former [2021/10]AL04.12.2019
AT04.12.2019
CZ04.12.2019
DK04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
IT04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
PL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SI04.12.2019
SK04.12.2019
SM04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
IS04.04.2020
PT29.04.2020
Former [2020/51]AL04.12.2019
AT04.12.2019
CZ04.12.2019
DK04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
PL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SI04.12.2019
SK04.12.2019
SM04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
IS04.04.2020
PT29.04.2020
Former [2020/47]AL04.12.2019
CZ04.12.2019
DK04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SK04.12.2019
SM04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
IS04.04.2020
PT29.04.2020
Former [2020/40]AL04.12.2019
CZ04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SK04.12.2019
SM04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
IS04.04.2020
PT29.04.2020
Former [2020/37]AL04.12.2019
CZ04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
SK04.12.2019
SM04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
PT29.04.2020
Former [2020/36]AL04.12.2019
CZ04.12.2019
EE04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
PT29.04.2020
Former [2020/35]AL04.12.2019
CZ04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
RO04.12.2019
RS04.12.2019
SE04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
Former [2020/34]AL04.12.2019
ES04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
RS04.12.2019
SE04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
Former [2020/32]AL04.12.2019
FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
NL04.12.2019
RS04.12.2019
SE04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
Former [2020/26]FI04.12.2019
HR04.12.2019
LT04.12.2019
LV04.12.2019
RS04.12.2019
SE04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
Former [2020/23]FI04.12.2019
LT04.12.2019
LV04.12.2019
SE04.12.2019
BG04.03.2020
NO04.03.2020
GR05.03.2020
Former [2020/22]FI04.12.2019
LT04.12.2019
SE04.12.2019
BG04.03.2020
NO04.03.2020
Former [2020/21]NO04.03.2020
Documents cited:Search[I]WO2005014533  (TRANSTECH PHARMA INC [US], et al) [I] 1-15 * claims 1, 33-44, 97-117 *;
 [A]JP2005298628  (SUMITOMO CHEMICAL CO) [A] 1-11 * claim 1 *;
 [A]WO2007070826  (SQUIBB BRISTOL MYERS CO [US], et al) [A] 1-15 * the whole document *;
 [A]WO2008157162  (SQUIBB BRISTOL MYERS CO [US], et al) [A] 1-15* the whole document *;
 [A]WO2013055984  (SQUIBB BRISTOL MYERS CO [US]) [A] 1-15 * the whole document *;
 [A]WO2013056034  (SQUIBB BRISTOL MYERS CO [US]) [A] 1-15 * the whole document *
International search[X]JP2005298628  (SUMITOMO CHEMICAL CO);
 [A]US2006211720  (GLUNZ PETER W [US], et al);
 [A]US2009181983  (CORTE JAMES R [US]);
 [A]US2011021492  (CORTE JAMES R [US], et al);
 [A]US2011028446  (PINTO DONALD J P [US], et al);
 [A]US2011059958  (NISHIDA HIDEMITSU [JP], et al);
 [A]US2011135650  (CHACKALAMANNIL SAMUEL [US], et al);
 [A]US2012041190  (CORTE JAMES R [US], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.