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Extract from the Register of European Patents

EP About this file: EP3058819

EP3058819 - HLA CLASS I EXPRESSING NON-HUMAN ANIMAL [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  25.03.2022
Database last updated on 27.07.2024
FormerThe patent has been granted
Status updated on  16.04.2021
FormerGrant of patent is intended
Status updated on  06.12.2020
FormerExamination is in progress
Status updated on  27.07.2018
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR		published on 17.07.2024  [2024/29]
Applicant(s)For all designated states
Taiho Pharmaceutical Co., Ltd.
1-27, Kanda Nishiki-cho
Chiyoda-ku
Tokyo 101-8444 / JP
[2016/34]
Inventor(s)01 / HARADA Naomoto
c/o Taiho Pharmaceutical Co. Ltd.
3 Okubo
Tsukuba-shi Ibaraki 300-2611 / JP
02 / FUKAYA Satoshi
c/o Taiho Pharmaceutical Co. Ltd.
3 Okubo
Tsukuba-shi Ibaraki 300-2611 / JP
 [2016/34]
Representative(s)Altmann Stößel Dick Patentanwälte PartG mbB
Theodor-Heuss-Anlage 2
68165 Mannheim / DE
[N/P]
Former [2021/20]Altmann Stößel Dick Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
Former [2016/34]Herzog, Fiesser & Partner Patentanwälte PartG mbB
Patentanwälte
Dudenstrasse 46
68167 Mannheim / DE
Application number, filing date14853234.417.10.2014
[2016/34]
WO2014JP77668
Priority number, dateJP2013021768418.10.2013         Original published format: JP 2013217684
[2016/34]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015056774
Date:23.04.2015
Language:JA
[2015/16]
Type: A1 Application with search report 
No.:EP3058819
Date:24.08.2016
Language:EN
[2016/34]
Type: B1 Patent specification 
No.:EP3058819
Date:19.05.2021
Language:EN
[2021/20]
Search report(s)International search report - published on:JP23.04.2015
(Supplementary) European search report - dispatched on:EP18.04.2017
ClassificationIPC:C07K14/74, A01K67/027, G01N33/50
[2017/20]
CPC:
A01K67/0278 (EP,US); C07K14/70539 (EP,US); C12N15/907 (US);
G01N33/5008 (EP,US); G01N33/5014 (US); G01N33/5023 (US);
G01N33/505 (US); G01N33/5088 (US); A01K2207/15 (US);
A01K2217/072 (EP,US); A01K2227/105 (EP,US); A01K2267/0387 (EP,US);
C07K2319/00 (EP,US); C07K2319/02 (EP); G01N2333/70539 (US) (-)
Former IPC [2016/34]A01K67/027, C12N5/10, C12N15/09, C12Q1/02
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/34]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:HLA-KLASSE I EXPRIMIERENDES NICHTMENSCHLICHES TIER[2016/34]
English:HLA CLASS I EXPRESSING NON-HUMAN ANIMAL[2016/34]
French:ANIMAL NON HUMAIN EXPRIMANT UNE MOLÉCULE HLA CLASSE I[2016/34]
Entry into regional phase09.05.2016Translation filed 
09.05.2016National basic fee paid 
09.05.2016Search fee paid 
09.05.2016Designation fee(s) paid 
09.05.2016Examination fee paid 
Examination procedure09.05.2016Examination requested  [2016/34]
12.10.2017Amendment by applicant (claims and/or description)
27.07.2018Despatch of a communication from the examining division (Time limit: M04)
07.11.2018Reply to a communication from the examining division
01.02.2019Despatch of a communication from the examining division (Time limit: M04)
10.05.2019Reply to a communication from the examining division
09.09.2019Despatch of a communication from the examining division (Time limit: M04)
13.01.2020Reply to a communication from the examining division
25.05.2020Despatch of a communication from the examining division (Time limit: M02)
24.06.2020Reply to a communication from the examining division
07.12.2020Communication of intention to grant the patent
08.04.2021Fee for grant paid
08.04.2021Fee for publishing/printing paid
08.04.2021Receipt of the translation of the claim(s)
Opposition(s)22.02.2022No opposition filed within time limit [2022/17]
Fees paidRenewal fee
24.10.2016Renewal fee patent year 03
23.10.2017Renewal fee patent year 04
26.10.2018Renewal fee patent year 05
25.10.2019Renewal fee patent year 06
23.10.2020Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU17.10.2014
AL19.05.2021
AT19.05.2021
CY19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
MK19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
TR19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
IE17.10.2021
LU17.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
[2024/29]
Former [2024/22]HU17.10.2014
AL19.05.2021
AT19.05.2021
CY19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
MK19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
IE17.10.2021
LU17.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2023/30]HU17.10.2014
AL19.05.2021
AT19.05.2021
CY19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
IE17.10.2021
LU17.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2023/27]HU17.10.2014
AL19.05.2021
AT19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
IE17.10.2021
LU17.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2022/48]AL19.05.2021
AT19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
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LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
IE17.10.2021
LU17.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2022/37]AL19.05.2021
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CZ19.05.2021
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EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
LU17.10.2021
BE31.10.2021
CH31.10.2021
LI31.10.2021
Former [2022/35]AL19.05.2021
AT19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
LU17.10.2021
BE31.10.2021
Former [2022/33]AL19.05.2021
AT19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
BE31.10.2021
Former [2022/29]AL19.05.2021
AT19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
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LT19.05.2021
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NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/26]AL19.05.2021
AT19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
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SE19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
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CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
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NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/10]AT19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
PT20.09.2021
IS22.12.2021
Former [2022/09]AT19.05.2021
CZ19.05.2021
DK19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
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NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/08]AT19.05.2021
CZ19.05.2021
DK19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/07]AT19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/04]AT19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2021/52]AT19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2021/51]AT19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
RS19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2021/50]AT19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
PT20.09.2021
Former [2021/49]AT19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
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Documents cited:Search[XA]  - BOUCHERMA R ET AL, "HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 Monochain Transgenic/H-2 Class I Null Mice: Novel Versatile Preclinical Models of Human T Cell Responses", THE JOURNAL OF IMMUNOLOGY, THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 191, no. 2, doi:10.4049/JIMMUNOL.1300483, ISSN 0022-1767, (20130715), pages 583 - 593, (20130617), XP002744179 [X] 18 * page 584, column l, paragraph 4 - column r, paragraph 2 * [A] 1-17,19-31

DOI:   http://dx.doi.org/10.4049/jimmunol.1300483
 [XA]  - E. CHEUK ET AL, "Human MHC Class I Transgenic Mice Deficient for H2 Class I Expression Facilitate Identification and Characterization of New HLA Class I-Restricted Viral T Cell Epitopes", THE JOURNAL OF IMMUNOLOGY, US, (20021115), vol. 169, no. 10, doi:10.4049/jimmunol.169.10.5571, ISSN 0022-1767, pages 5571 - 5580, XP055361468 [X] 18 * page 5572, column l, paragraphs 2,3 * [A] 1-17,19-31

DOI:   http://dx.doi.org/10.4049/jimmunol.169.10.5571
 [T]  - NAOMOTO HARADA ET AL, "Generation of a Novel HLA Class I Transgenic Mouse Model Carrying a Knock-in Mutation at the [beta] 2 -Microglobulin Locus", THE JOURNAL OF IMMUNOLOGY, US, (20161123), vol. 198, no. 1, doi:10.4049/jimmunol.1502367, ISSN 0022-1767, pages 516 - 527, XP055361434 [T] 1-31 * page 516 - page 527 * * figure 1 *

DOI:   http://dx.doi.org/10.4049/jimmunol.1502367
International search[Y]US2005066375  (THIAM KADER [FR], et al);
 [Y]WO2013063346  (REGENERON PHARMA [US]);
 [Y]  - PASCOLO S. ET AL., "HLA-A2.1-RESTRICTED EDUCATION AND CYTOLYTIC ACTIVITY OF CD8+ T", J. EXP. MED., (1997), vol. 185, no. 12, doi:MPHOCYTES FROM BETA-2 MICROGLOBULIN (BETA-2M), pages 2043 - 2051, XP002469861

DOI:   http://dx.doi.org/10.1084/jem.185.12.2043
 [A]  - FIRAT H. ET AL., "H-2 class I knockout, HLA- A2.1-transgenic mice: a versatile animal model for preclinical evaluation of antitumor immunotherapeutic strategies", EUR. J. IMMUNOL., (1999), vol. 29, pages 3112 - 3121, XP002162347

DOI:   http://dx.doi.org/10.1002/(SICI)1521-4141(199910)29:10<3112::AID-IMMU3112>3.0.CO;2-Q
 [A]  - KALINKE U. ET AL., "Strong xenogeneic HLA response in transgenic mice after introducing an a3 domain into HLA B27", NATURE, (1990), vol. 348, no. 13, pages 642 - 644, XP055052576

DOI:   http://dx.doi.org/10.1038/348642a0
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.