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Extract from the Register of European Patents

EP About this file: EP3071575

EP3071575 - PREPARATION OF NORMORPHINANS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.09.2020
Database last updated on 31.08.2024
FormerThe patent has been granted
Status updated on  11.10.2019
FormerGrant of patent is intended
Status updated on  20.06.2019
FormerExamination is in progress
Status updated on  16.03.2018
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK
published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
SpecGx LLC
385 Marshall Avenue
Webster Groves, Missouri 63119 / US
[2018/28]
Former [2018/16]For all designated states
SpecGx, LLC
385 Marshall Avenue
Webster Groves, Missouri 63119 / US
Former [2016/39]For all designated states
Mallinckrodt LLC
675 McDonnell Boulevard
Hazelwood, MO 63042 / US
Inventor(s)01 / BRANDT, John
Mallinckdrot LLC
675 McDonnell Blvd.
Hazelwood, Missouri 63042 / US
02 / LIAO, Subo
Mallinckrodt LLC
675 McDonnell Blvd.
Hazelwood, Missouri 63042 / US
03 / HUDSON, Edmund C.
Mallinckrodt LLC
675 McDonnell Blvd.
Hazelwood, Missouri 63042 / US
04 / JARVI, Esa T.
Mallinckrodt LLC
675 McDonnell Blvd.
Hazelwood, Missouri 63042 / US
05 / WANG, Peter X.
Mallinckrodt LLC
675 McDonnell Blvd.
Hazelwood, Missouri 63042 / US
06 / SCHAEFER, Michael
Mallinckrodt LLC
675 McDonnell Blvd.
Hazelwood, Missouri 63042 / US
 [2016/39]
Representative(s)Jones, Nicholas Andrew
Withers & Rogers LLP
2 London Bridge
London SE1 9RA / GB
[N/P]
Former [2016/39]Jones, Nicholas Andrew
Withers & Rogers LLP
4 More London Riverside
London, SE1 2AU / GB
Application number, filing date14862986.818.11.2014
[2016/39]
WO2014US66152
Priority number, dateUS201361905312P18.11.2013         Original published format: US 201361905312 P
[2016/39]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015074049
Date:21.05.2015
Language:EN
[2015/20]
Type: A1 Application with search report 
No.:EP3071575
Date:28.09.2016
Language:EN
The application published by WIPO in one of the EPO official languages on 21.05.2015 takes the place of the publication of the European patent application.
[2016/39]
Type: B1 Patent specification 
No.:EP3071575
Date:13.11.2019
Language:EN
[2019/46]
Search report(s)International search report - published on:US21.05.2015
(Supplementary) European search report - dispatched on:EP17.03.2017
ClassificationIPC:C07D489/02
[2016/39]
CPC:
C07D489/02 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/39]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:HERSTELLUNG VON NORMORPHINANEN[2016/39]
English:PREPARATION OF NORMORPHINANS[2016/39]
French:PRÉPARATION DE NORMORPHINANES[2016/39]
Entry into regional phase07.06.2016National basic fee paid 
07.06.2016Search fee paid 
07.06.2016Designation fee(s) paid 
07.06.2016Examination fee paid 
Examination procedure07.06.2016Examination requested  [2016/39]
12.10.2017Amendment by applicant (claims and/or description)
15.03.2018Despatch of a communication from the examining division (Time limit: M04)
23.07.2018Reply to a communication from the examining division
19.10.2018Despatch of a communication from the examining division (Time limit: M04)
15.02.2019Reply to a communication from the examining division
21.06.2019Communication of intention to grant the patent
30.09.2019Fee for grant paid
30.09.2019Fee for publishing/printing paid
30.09.2019Receipt of the translation of the claim(s)
Opposition(s)14.08.2020No opposition filed within time limit [2020/43]
Fees paidRenewal fee
28.11.2016Renewal fee patent year 03
27.11.2017Renewal fee patent year 04
27.11.2018Renewal fee patent year 05
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.11.2014
AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
MK13.11.2019
MT13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.11.2019
LU18.11.2019
BE30.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
[2022/31]
Former [2021/34]HU18.11.2014
AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
MT13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.11.2019
LU18.11.2019
BE30.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2021/33]HU18.11.2014
AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.11.2019
LU18.11.2019
BE30.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2021/26]AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.11.2019
LU18.11.2019
BE30.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/51]AL13.11.2019
AT13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.11.2019
LU18.11.2019
BE30.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/46]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SK13.11.2019
SM13.11.2019
IE18.11.2019
LU18.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/39]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SK13.11.2019
SM13.11.2019
LU18.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/37]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SK13.11.2019
SM13.11.2019
LU18.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/36]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
LU18.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/35]AL13.11.2019
CZ13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
LU18.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/34]AL13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
RS13.11.2019
SE13.11.2019
CH30.11.2019
LI30.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/32]AL13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
RS13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/26]FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
RS13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/24]FI13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/23]FI13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
PT13.03.2020
Former [2020/22]FI13.11.2019
LT13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
PT13.03.2020
Former [2020/21]NO13.02.2020
Documents cited:Search[Y]US2012035367  (LIAO SUBO [US], et al) [Y] 1-7,11-15 * claims 13, 16, 18, 20 * * paragraph [0013] * * paragraph [0026] * * paragraph [0039] * * paragraph [0041] - paragraph [0043] * * paragraph [0045] * * paragraph [0047] * * paragraph [0060] * * paragraph [0062] * * examples 1, 5 *;
 [Y]  - JINDA FAN ET AL, "Chemical and Enzyme-Assisted Synthesis of Norbuprenorphine-3-beta-D-glucuronide", BIOCONJUGATE CHEMISTRY, (20110420), vol. 22, no. 4, doi:10.1021/bc100550u, ISSN 1043-1802, pages 752 - 758, XP055352823 [Y] 1-7,11-15 * scheme 2; page 754 *

DOI:   http://dx.doi.org/10.1021/bc100550u
 [Y]  - JACQUEMARD U ET AL, "Mild and selective deprotection of carbamates with Bu"4NF", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (20041025), vol. 60, no. 44, doi:10.1016/J.TET.2004.07.071, ISSN 0040-4020, pages 10039 - 10047, XP004580207 [Y] 1-7,11-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.tet.2004.07.071
International search[A]US2011015219  (TRAWICK BOBBY N [US], et al);
 [A]US8101757  (WANG PETER X [US], et al);
 [X]US2012035367  (LIAO SUBO [US], et al)
by applicantUS2012035367
    - FAN et al., "have reported chemical and enzyme-assisted syntheses of norbuprenorphine-3-P-D-glucuronide", Bioconjugate Chemistry, (20110000), vol. 22, pages 752 - 758
    - JACUEMARD et al., "have reported the mild and selective deprotection of carbamates with Bu NF", Tetrahedron, (20040000), vol. 60, pages 10039 - 10047
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