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Extract from the Register of European Patents

EP About this file: EP3085698

EP3085698 - PAIN-RELATED COMPOUND AND MEDICINAL COMPOSITION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.09.2020
Database last updated on 15.07.2024
FormerThe patent has been granted
Status updated on  11.10.2019
FormerGrant of patent is intended
Status updated on  21.07.2019
FormerExamination is in progress
Status updated on  16.03.2018
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Kyoto University
36-1, Yoshida-honmachi Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
For all designated states
Kagoshima University
21-24, Korimoto 1-chome
Kagoshima-shi, Kagoshima 890-8580 / JP
[2017/38]
Former [2016/43]For all designated states
Kyoto University
36-1, Yoshida-honmachi Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
For all designated states
National University Corporation Tokyo Medical and Dental University
5-45 Yushima 1-chome Bunkyo-ku
Tokyo 113-8510 / JP
For all designated states
Kagoshima University
21-24, Korimoto 1-chome
Kagoshima-shi, Kagoshima 890-8580 / JP
Inventor(s)01 / HAGIWARA, Masatoshi
c/o KYOTO UNIVERSITY
36-1 Yoshida-honmachi
Sakyo-ku
Kyoto-shi Kyoto 606-8501 / JP
02 / TOYOMOTO, Masayasu
c/o KYOTO UNIVERSITY
36-1 Yoshida-honmachi
Sakyo-ku
Kyoto-shi Kyoto 606-8501 / JP
03 / HOSOYA, Takamitsu
c/o NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
5-45 Yushima 1-chome
Bunkyo-ku
Tokyo 113-8510 / JP
04 / YOSHIDA, Suguru
c/o NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
5-45 Yushima 1-chome
Bunkyo-ku
Tokyo 113-8510 / JP
05 / KURIHARA, Takashi
c/o KAGOSHIMA UNIVERSITY
21-24 Korimoto 1-chome
Kagoshima-shi Kagoshima 890-8580 / JP
 [2016/43]
Representative(s)Dehns
St. Bride's House
10 Salisbury Square
London EC4Y 8JD / GB
[2019/46]
Former [2016/43]Jones, Elizabeth Louise
Dehns
St Bride's House
10 Salisbury Square
London
EC4Y 8JD / GB
Application number, filing date14871323.318.12.2014
[2016/43]
WO2014JP83569
Priority number, dateJP2013026139618.12.2013         Original published format: JP 2013261396
[2016/43]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015093567
Date:25.06.2015
Language:JA
[2015/25]
Type: A1 Application with search report 
No.:EP3085698
Date:26.10.2016
Language:EN
[2016/43]
Type: B1 Patent specification 
No.:EP3085698
Date:13.11.2019
Language:EN
[2019/46]
Search report(s)International search report - published on:JP25.06.2015
(Supplementary) European search report - dispatched on:EP03.05.2017
ClassificationIPC:C07D277/64, A61K31/428, A61P25/04, A61P29/00
[2016/43]
CPC:
C07D277/64 (EP,US); A61P25/04 (EP); A61P29/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/43]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:SCHMERZASSOZIIERTE VERBINDUNG UND MEDIZINISCHE ZUSAMMENSETZUNG[2016/43]
English:PAIN-RELATED COMPOUND AND MEDICINAL COMPOSITION[2016/43]
French:COMPOSÉ ASSOCIÉ À LA DOULEUR ET COMPOSITION MÉDICINALE[2016/43]
Entry into regional phase08.07.2016Translation filed 
08.07.2016National basic fee paid 
08.07.2016Search fee paid 
08.07.2016Designation fee(s) paid 
08.07.2016Examination fee paid 
Examination procedure08.07.2016Examination requested  [2016/43]
29.11.2017Amendment by applicant (claims and/or description)
16.03.2018Despatch of a communication from the examining division (Time limit: M04)
26.07.2018Reply to a communication from the examining division
05.11.2018Despatch of a communication from the examining division (Time limit: M04)
14.03.2019Reply to a communication from the examining division
22.07.2019Communication of intention to grant the patent
03.10.2019Fee for grant paid
03.10.2019Fee for publishing/printing paid
03.10.2019Receipt of the translation of the claim(s)
Opposition(s)14.08.2020No opposition filed within time limit [2020/43]
Fees paidRenewal fee
20.12.2016Renewal fee patent year 03
19.12.2017Renewal fee patent year 04
18.12.2018Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.12.2014
AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
IT13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
MK13.11.2019
MT13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
TR13.11.2019
IE18.12.2019
LU18.12.2019
BE31.12.2019
CH31.12.2019
LI31.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
[2022/31]
Former [2022/27]HU18.12.2014
AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
IT13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
MT13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
TR13.11.2019
IE18.12.2019
LU18.12.2019
BE31.12.2019
CH31.12.2019
LI31.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2021/34]HU18.12.2014
AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
IT13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
MT13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.12.2019
LU18.12.2019
BE31.12.2019
CH31.12.2019
LI31.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2021/33]HU18.12.2014
AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
IT13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.12.2019
LU18.12.2019
BE31.12.2019
CH31.12.2019
LI31.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2021/26]AL13.11.2019
AT13.11.2019
CY13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
IT13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.12.2019
LU18.12.2019
BE31.12.2019
CH31.12.2019
LI31.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2021/10]AL13.11.2019
AT13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
IT13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.12.2019
LU18.12.2019
BE31.12.2019
CH31.12.2019
LI31.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/51]AL13.11.2019
AT13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SI13.11.2019
SK13.11.2019
SM13.11.2019
IE18.12.2019
LU18.12.2019
BE31.12.2019
CH31.12.2019
LI31.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/46]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SK13.11.2019
SM13.11.2019
IE18.12.2019
LU18.12.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/39]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
MC13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SK13.11.2019
SM13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/37]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
SK13.11.2019
SM13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/36]AL13.11.2019
CZ13.11.2019
DK13.11.2019
EE13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/35]AL13.11.2019
CZ13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
RO13.11.2019
RS13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/34]AL13.11.2019
ES13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
RS13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/32]AL13.11.2019
FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
RS13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/25]FI13.11.2019
HR13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
RS13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/24]FI13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
IS13.03.2020
PT13.03.2020
Former [2020/23]FI13.11.2019
LT13.11.2019
LV13.11.2019
NL13.11.2019
PL13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
GR14.02.2020
PT13.03.2020
Former [2020/22]FI13.11.2019
LT13.11.2019
SE13.11.2019
BG13.02.2020
NO13.02.2020
PT13.03.2020
Former [2020/21]NO13.02.2020
Documents cited:Search[I]US3928327  (TAKAMIZAWA AKIRA, et al) [I] 1-10 * claim 1 ** column 4, table *;
 [XI]WO2007102861  (SIRTRIS PHARMACEUTICALS INC [US], et al) [X] 1-10 * claims 7, 35 * * page 121, line 32 - page 122, line 3 * * figure 14 * [I] 1-10
International search[X]JPS5089367  (SHIONOGI & CO., LTD.);
 [A]JP2004002352  (SANTEN PHARMA CO LTD);
 [X]US2005171026  (HAGIWARA MASATOSHI [JP], et al);
 [X]US2008255123  (MEYER MICHAEL D [US], et al);
 [X]WO2009085226  (SIRTRIS PHARMACEUTICALS INC [US], et al);
 [X]WO2010010797  (KINOPHARMA INC [JP], et al);
 [X]WO2013168826  (UNIV OSAKA [JP]);
 [X]  - MURAKI M. ET AL., "Manipulation of Alternative Splicing by a NewlyDeveloped Inhibitor of Clks", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (2004), vol. 279, no. 23, pages 24246 - 24254, XP055192700

DOI:   http://dx.doi.org/10.1074/jbc.M314298200
 [XP]  - KURIHARA, T. ET AL., "Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors", MOLECULAR PAIN, vol. 10, pages 17 /1 - 17/13, XP021180976

DOI:   http://dx.doi.org/10.1186/1744-8069-10-17
by applicantUS2005171026
 JP2008539269
 WO2010010797
    - M. MURAKI ET AL., "Manipulation of Alternative Splicing by a Newly Developed Inhibitor of Clks", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (2004), vol. 279, doi:doi:10.1074/jbc.M314298200, pages 24246 - 24254, XP055192700

DOI:   http://dx.doi.org/10.1074/jbc.M314298200
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