-
EP3085781
European procedure
- EP About this file
- EP Legal status
- EP Federated register
- EP Event history
- EP Citations
- EP Patent family
- EP All documents
Extract from the Register of European Patents
EP About this file: EP3085781
| EP3085781 - NOVEL FUSION GENE AS FACTOR RESPONSIBLE FOR STOMACH CANCER [Right-click to bookmark this link] | Status | The application has been withdrawn Status updated on 25.10.2016 Database last updated on 31.08.2024 | Most recent event Tooltip | 25.10.2016 | Withdrawal of application | published on 16.11.2016 [2016/46] | Applicant(s) | For all designated states National Cancer Center 1-1 Tsukiji 5-chome Chuo-ku Tokyo 104-0045 / JP | For all designated states LSIP, LLC 7-12, Marunouchi 1-chome Chiyoda-ku Tokyo 100-0005 / JP | [2016/43] | Inventor(s) | 01 /
SHIBATA, Tatsuhiro c/o National Cancer Center 5-1-1 Tsukiji Chuo-ku Tokyo 104-0045 / JP | 02 /
HOSODA, Fumie c/o National Cancer Center 5-1-1 Tsukiji Chuo-ku Tokyo 104-0045 / JP | [2016/43] | Representative(s) | Plasseraud IP 104 Rue de Richelieu CS92104 75080 Paris Cedex 02 / FR | [N/P] |
| Former [2016/43] | Cabinet Plasseraud 66, rue de la Chaussée d'Antin 75440 Paris Cedex 09 / FR | Application number, filing date | 14871677.2 | 18.12.2014 | [2016/43] | WO2014JP83526 | Priority number, date | JP20130263032 | 19.12.2013 Original published format: JP 2013263032 | [2016/43] | Filing language | JA | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2015093557 | Date: | 25.06.2015 | Language: | JA | [2015/25] | Type: | A1 Application with search report | No.: | EP3085781 | Date: | 26.10.2016 | Language: | EN | [2016/43] | Search report(s) | International search report - published on: | JP | 25.06.2015 | Classification | IPC: | C12N15/09, A61K45/00, A61P35/00, C07K19/00, C12N9/12, C12Q1/68, G01N33/574, C07K16/40 | [2016/43] | CPC: |
C12N9/12 (EP,US);
A61P35/00 (EP);
C07K14/47 (EP,US);
C07K14/4747 (EP,US);
C07K14/4756 (EP,US);
C07K14/705 (US);
C07K14/715 (EP,US);
C12N15/113 (US);
C12N15/1137 (US);
C12N9/93 (EP,US);
C12Q1/6886 (EP,US);
C12Y207/10001 (EP,US);
C12Y207/11001 (EP,US);
C12Y603/02 (EP,US);
G01N33/57446 (EP,US);
C07K2319/00 (EP,US);
C12N2310/14 (US);
C12Q2600/136 (US);
C12Q2600/156 (EP,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2016/43] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | NEUARTIGES FUSIONSGEN ALS FÜR MAGENKREBS VERANTWORTLICHER FAKTOR | [2016/43] | English: | NOVEL FUSION GENE AS FACTOR RESPONSIBLE FOR STOMACH CANCER | [2016/43] | French: | NOUVEAU GÈNE DE FUSION EN TANT QUE GÈNE RESPONSABLE DU CANCER DE L'ESTOMAC | [2016/43] | Entry into regional phase | 07.07.2016 | Translation filed | 07.07.2016 | National basic fee paid | 07.07.2016 | Search fee paid | 07.07.2016 | Designation fee(s) paid | 07.07.2016 | Examination fee paid | Examination procedure | 07.07.2016 | Examination requested [2016/43] | 11.10.2016 | Application withdrawn by applicant [2016/46] |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [A]WO2013133351 (ASTELLAS PHARMA INC [JP]); | [Y] - PALANISAMY NALLASIVAM ET AL., "Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma", NATURE MEDICINE, (2010), vol. 16, no. 7, doi:doi:10.1038/nm.2166, pages 793 - 798, XP008155779 DOI: http://dx.doi.org/10.1038/nm.2166 | [Y] - TAO JIONG ET AL., "CD 44-SLC1A2 Gene Fusions in Gastric Cancer", SCIENCE TRANSLATIONAL MEDICINE, (2011), vol. 3, no. ISSUE, pages 1 - 11 | [Y] - ZANG ZHI JIANG ET AL., "Genetic and Structural Variation in the Gastric Cancer Kinome Revealed through Targeted Deep Sequencing", CANCER RESEARCH, (2011), vol. 71, no. 1, doi:doi:10.1158/0008-5472.CAN-10-1749, pages 29 - 39, XP055226664 DOI: http://dx.doi.org/10.1158/0008-5472.CAN-10-1749 | [Y] - CHO GEUN-A ET AL., "Abstract 5078: Identification of novel gene fusions by RNA-seq in gastric cancer", CANCER RESEARCH, (2012), vol. 72, no. SUPPL., page 5078 | [Y] - YUN SUN MI, "Abstract 4304: PPP1R1B-STARD3 fusion gene promotes gastric tumorigenesis through activation of PI3K/Akt signaling.", CANCER RESEARCH, (201304), vol. 73, no. SUPPL., page 4304 | by applicant | WO2010064111 | - WANG J. D. ET AL., ONCOLOGY, (2007), vol. 73, no. 3-4, pages 238 - 45 | - SHENG Z. ET AL., PATHOBIOLOGY, (2008), vol. 75, no. 5, pages 274 - 80 | - SHITASHIGE M. ET AL., CANCER RES, (2010), vol. 70, no. 12, pages 5024 - 33 | - JIAO X. ET AL., BMC GENOMICS, (2013), vol. 14, page 165 | - GARZON-MUVDI T. ET AL., PLOS BIOL, (2012), vol. 10, no. 5, page E1001320 | - REVILLION F. ET AL., ANN ONCOL, (2008), vol. 19, no. 1, pages 73 - 80 | - TANIDA I.; TANIDA-MIYAKE E.; KOMATSU M.; UENO T.; KOMINAMI E., "Human Apg3p/Autlp homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApgl2p to hApg5p", JBIOL CHEM., (20020419), vol. 277, no. 16, pages 13739 - 44 | - VINDIS C.; CERRETTI D. P.; DANIEL T. O.; HUYNH-DO U., "EphBl recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis", J CELL BIOL., (20030818), vol. 162, no. 4, doi:doi:10.1083/jcb.200302073, pages 661 - 71, XP002414039 DOI: http://dx.doi.org/10.1083/jcb.200302073 | - ALTSCHUL S. F. ET AL., J. MOL. BIOL., (1990), vol. 215, page 403 | - KARLIN; ALTSCHUL, PROC. NATL. ACAD. SCI. USA, (1990), vol. 87, pages 2264 - 2268 | - PROC. NATL. ACAD. SCI. USA, (1993), vol. 90, page 5873 | - FU C. A.; SHEN M.; HUANG B. C.; LASAGA J.; PAYAN D. G.; LUO Y., "TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton", J BIOL CHEM., (19991022), vol. 274, no. 43, doi:doi:10.1074/jbc.274.43.30729, pages 30729 - 37, XP002173259 DOI: http://dx.doi.org/10.1074/jbc.274.43.30729 | - MAHMOUDI T.; LI V. S.; NG S. S.; TAOUATAS N.; VRIES R. G.; MOHAMMED S.; HECK A. J.; CLEVERS H., "The kinase TNIK is an essential activator of Wnt target genes", EMBOJ., (20091104), vol. 28, no. 21, doi:doi:10.1038/EMBOJ.2009.285, pages 3329 - 40, XP002644396 DOI: http://dx.doi.org/10.1038/EMBOJ.2009.285 | - KAMURA T.; HARA T.; MATSUMOTO M.; ISHIDA N.; OKUMURA F.; HATAKEYAMA S.; YOSHIDA M.; NAKAYAMA K.; NAKAYAMA K. I., "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kipl) at G1 phase", NAT CELL BIOL., (200412), vol. 6, no. 12, pages 1229 - 35 | - KAMURA, T. ET AL., NATURE CELL BIOLOGY, (2004), vol. 6, no. 12, pages 1229 - 35 | - SOMASEKHARAN S.; TANIS J.; FORBUSH B., "Loop diuretic and ion-binding residues revealed by scanning mutagenesis of transmembrane helix 3 (TM3) of Na-K-Cl cotransporter (NKCC1", J BIOL CHEM., (20120518), vol. 287, no. 21, pages 17308 - 17 | - CHANG H.; RIESE D. J. 2ND; GILBERT W.; STERN D. F.; MCMAHAN U. J., "Ligands for ErbB-family receptors encoded by a neuregulin-like gene", NATURE, (19970529), vol. 387, no. 6632, pages 509 - 12, XP002636460 | - CARRAWAY K. L. 3RD; WEBER J. L.; UNGER M. J.; LEDESMA J.; YU N.; GASSMANN M.; LAI C., "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases", NATURE, (19970529), vol. 387, no. 6632, doi:doi:10.1038/387512a0, pages 512 - 6, XP000919297 DOI: http://dx.doi.org/10.1038/387512a0 | - HOBBS S. S.; COFFING S. L.; LE A. T.; CAMERON E. M.; WILLIAMS E. E.; ANDREW M.; BLOMMEL E. N.; HAMMER R. P.; CHANG H.; RIESE D. J., "Neuregulin isoforms exhibit distinct patterns of ErbB family receptor activation", ONCOGENE, (20021205), vol. 21, no. 55, doi:doi:10.1038/sj.onc.1205960, pages 8442 - 52, XP009053189 DOI: http://dx.doi.org/10.1038/sj.onc.1205960 | - NAKANO N.; HIGASHIYAMA S.; OHMOTO H.; ISHIGURO H.; TANIGUCHI N.; WADA Y., "The N-terminal region of NTAK/neuregulin-2 isoforms has an inhibitory activity on angiogenesis", JBIOL CHERN., (20040319), vol. 279, no. 12, pages 11465 - 70 | - WILSON, T. R. ET AL., CANCER CELL, (2011), vol. 20, pages 158 - 172 | - HO K. K. ET AL., BIOORG MED CHEM LETT, 2013, (20121116), vol. 23, no. 2, pages 569 - 73 | - KRAMER, W.; FRITZ, H. J., METHODS ENZYMOL., (1987), vol. 154, page 350 | - MEYERSON, M. ET AL., NAT. REV. GENET., (2010), vol. 11, pages 685 - 696 |