EP3087182 - METHODS AND COMPOSITIONS FOR TREATING CANCER USING PEPTIDE NUCLEIC ACID-BASED AGENTS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 24.01.2020 Database last updated on 24.08.2024 | |
Former | The patent has been granted Status updated on 15.02.2019 | ||
Former | Grant of patent is intended Status updated on 27.09.2018 | ||
Former | Examination is in progress Status updated on 04.05.2018 | Most recent event Tooltip | 01.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 03.08.2022 [2022/31] | Applicant(s) | For all designated states Memorial Sloan-Kettering Cancer Center 1275 York Avenue New York, NY 10065 / US | [2018/43] |
Former [2016/44] | For all designated states Memorial Sloan Kettering Cancer Center 1275 York Avenue New York, NY 10065 / US | Inventor(s) | 01 /
ROTHMAN, Jeffrey K. c/o Memorial Sloan-Kettering Cancer Center 1275 York Avenue New York, New York 10065 / US | 02 /
SCHWARTZ, Gary K. 11 Hidden Oak Road Briarcliff Manor, New York 10510 / US | [2016/44] | Representative(s) | Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB Ganghoferstraße 68 B 80339 München / DE | [2019/12] |
Former [2016/44] | Schiweck, Weinzierl & Koch European Patent Attorneys Landsberger Straße 98 80339 München / DE | Application number, filing date | 14875786.7 | 17.12.2014 | [2016/44] | WO2014US70970 | Priority number, date | US201361920289P | 23.12.2013 Original published format: US 201361920289 P | [2016/44] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2015100113 | Date: | 02.07.2015 | Language: | EN | [2015/26] | Type: | A2 Application without search report | No.: | EP3087182 | Date: | 02.11.2016 | Language: | EN | The application published by WIPO in one of the EPO official languages on 02.07.2015 takes the place of the publication of the European patent application. | [2016/44] | Type: | B1 Patent specification | No.: | EP3087182 | Date: | 20.03.2019 | Language: | EN | [2019/12] | Search report(s) | International search report - published on: | US | 29.10.2015 | (Supplementary) European search report - dispatched on: | EP | 21.07.2017 | Classification | IPC: | C12N15/113 | [2018/42] | CPC: |
C12N15/1135 (EP,US);
A61P35/00 (EP,US);
A61P43/00 (EP);
C07K14/003 (US);
C12Q1/6886 (US);
G01N33/5011 (EP);
G01N33/5082 (EP);
G01N33/5748 (US);
G01N33/68 (EP);
A61K38/00 (EP,US);
C12N2310/11 (EP);
C12N2310/3181 (EP,US);
C12N2310/3513 (EP,US);
C12N2310/3515 (EP,US);
C12N2310/531 (US);
C12N2320/30 (EP,US);
C12Q2600/136 (US);
C12Q2600/158 (US);
G01N2500/10 (US)
(-)
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Former IPC [2017/34] | C12N15/11, C12N15/113 | ||
Former IPC [2016/44] | C12N15/11, C07H21/04 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2016/44] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON KREBS UNTER VERWENDUNG VON PEPTIDNUKLEINSÄUREBASIERTEM WIRKSTOFF | [2016/44] | English: | METHODS AND COMPOSITIONS FOR TREATING CANCER USING PEPTIDE NUCLEIC ACID-BASED AGENTS | [2016/44] | French: | MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT DU CANCER UTILISANT DES AGENTS À BASE D'ACIDES NUCLÉIQUES DE PEPTIDES | [2016/44] | Entry into regional phase | 21.07.2016 | National basic fee paid | 21.07.2016 | Search fee paid | 21.07.2016 | Designation fee(s) paid | 21.07.2016 | Examination fee paid | Examination procedure | 21.07.2016 | Examination requested [2016/44] | 12.02.2018 | Amendment by applicant (claims and/or description) | 08.05.2018 | Despatch of a communication from the examining division (Time limit: M02) | 19.06.2018 | Reply to a communication from the examining division | 28.09.2018 | Communication of intention to grant the patent | 29.01.2019 | Receipt of the translation of the claim(s) | 07.02.2019 | Fee for grant paid | 07.02.2019 | Fee for publishing/printing paid | Divisional application(s) | EP19163891.5 / EP3581653 | Opposition(s) | 02.01.2020 | No opposition filed within time limit [2020/09] | Fees paid | Renewal fee | 27.12.2016 | Renewal fee patent year 03 | 12.12.2017 | Renewal fee patent year 04 | 21.12.2018 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 17.12.2014 | AL | 20.03.2019 | CY | 20.03.2019 | EE | 20.03.2019 | FI | 20.03.2019 | HR | 20.03.2019 | LT | 20.03.2019 | LV | 20.03.2019 | MC | 20.03.2019 | MK | 20.03.2019 | MT | 20.03.2019 | RO | 20.03.2019 | RS | 20.03.2019 | SI | 20.03.2019 | SK | 20.03.2019 | SM | 20.03.2019 | TR | 20.03.2019 | BG | 20.06.2019 | GR | 21.06.2019 | IS | 20.07.2019 | PT | 20.07.2019 | LU | 17.12.2019 | [2022/31] |
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LT | 20.03.2019 | Documents cited: | Search | [Y]WO2008043366 (UNIV KOEBENHAVN [DK], et al) [Y] 1-15 * page 14 - page 15; figures 1-11; examples 1-7 *; | [Y] - KOPPELHUS U ET AL, "Improved cellular activity of antisense peptide nucleic acids by conjugation to a cationic peptide-lipid (CatLip) domain", BIOCONJUGATE CHEMISTRY,, vol. 19, doi:10.1021/BC800068H, ISSN 1043-1802, (20080101), pages 1526 - 1534, (20080723), XP003026360 [Y] 1-15 * table 1 * DOI: http://dx.doi.org/10.1021/BC800068H | [Y] - KLAUS ALBERTSHOFER ET AL, "Structure-Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid", JOURNAL OF MEDICINAL CHEMISTRY, (20051001), vol. 48, no. 21, doi:10.1021/jm050490b, ISSN 0022-2623, pages 6741 - 6749, XP055074967 [Y] 1-15 * page 6745 - page 6746; figure 2 * DOI: http://dx.doi.org/10.1021/jm050490b | [A] - JIAXIN HU ET AL, "Inhibiting Gene Expression with Peptide Nucleic Acid (PNA)-Peptide Conjugates That Target Chromosomal DNA +", BIOCHEMISTRY, US, (20070601), vol. 46, no. 25, doi:10.1021/bi700230a, ISSN 0006-2960, pages 7581 - 7589, XP055390173 [A] 1-15 * figure 8; table 1 * DOI: http://dx.doi.org/10.1021/bi700230a | International search | [XY] - TORRES et al., "Chemical structure requirements and cellular targeting of microRNA-122 by peptide nudeic acids anti-miRs.", Nucleic Acids Res., (20120000), vol. 40, no. 5, pages 2152 - 67, XP055233667 [X] 1-3, 5, 12 * ; Abstract, pg 2153, col 1 and Table 1 * [Y] 4, 6 DOI: http://dx.doi.org/10.1093/nar/gkr885 | [Y] - SHEN et al., "Phospholipid conjugate for intracellular delivery of peptide nucleic acids.", Bioconjug Chem., (20090000), vol. 20, no. 9, pages 1729 - 1736, XP055233669 [Y] 4, 6/4 * ; Abstract, pg 5[according to the posted document], 1st para * DOI: http://dx.doi.org/10.1021/bc900048y | [Y] - KAIHATSU et al., "Extending recognition by peptide nucleic acids (PNAs): binding to duplex DNA and inhibition of transcription by tail-clamp PNA-peptide conjugates.", Biochemistry, (20030000), vol. 42, no. 47, pages 13996 - 14003, XP002597006 [Y] 6 * ; Abstract, pg 13996, col 2 * DOI: http://dx.doi.org/10.1021/BI035194K |