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Extract from the Register of European Patents

EP About this file: EP3125919

EP3125919 - CHEMOKINE RECEPTOR ANTAGONIST AND ITS COMBINATIONAL THERAPY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  30.11.2018
Database last updated on 11.09.2024
FormerRequest for examination was made
Status updated on  06.01.2017
FormerThe international publication has been made
Status updated on  09.11.2016
Most recent event   Tooltip30.11.2018Application deemed to be withdrawnpublished on 02.01.2019  [2019/01]
Applicant(s)For all designated states
Microconstants China Inc.
Suite 1-201 Bldg. 18
99 Kechuang 14th Street
Huilongsen International Science & Technology Park
BDA
Beijing 101111 / CN
For all designated states
Pertinax Therapeutics Inc.
Suite 205 Markham Convergence Centre
7271 Warden Avenue
Markham
Ontario, Canada L3R 5X5 / CA
[2017/06]
Inventor(s)01 / INCLEDON, Beverly James
13306 Nassagaweya
6th Line
Acton, Ontario L7J 2L7 / CA
02 / LEE, Yiu-Chung
79 Pearmain Court
Markham, Ontario L3S 3S7 / CA
03 / YANG, Qicheng David
7349 Mannix Court
San Diego, CA 92129 / US
 [2017/06]
Representative(s)Kilger, Ute
Boehmert & Boehmert
Anwaltspartnerschaft mbB
Pettenkoferstrasse 22
80336 München / DE
[N/P]
Former [2017/06]Kilger, Ute
Boehmert & Boehmert
Anwaltspartnerschaft mbB
Patentanwälte Rechtsanwälte
Pettenkoferstrasse 20-22
80336 München / DE
Application number, filing date14882875.919.02.2014
[2017/06]
WO2014CN72239
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015123818
Date:27.08.2015
Language:EN
[2015/34]
Type: A1 Application with search report 
No.:EP3125919
Date:08.02.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 27.08.2015 takes the place of the publication of the European patent application.
[2017/06]
Search report(s)International search report - published on:CN27.08.2015
(Supplementary) European search report - dispatched on:EP01.12.2017
ClassificationIPC:A61K38/08, A61K38/06, C07K7/06, C07K7/08
[2017/06]
CPC:
A61K38/10 (EP,KR,US); A61K31/282 (EP,US); A61K31/337 (KR);
A61K31/404 (EP,US); A61K31/44 (EP,KR,US); A61K31/4745 (EP,KR,US);
A61K31/506 (EP,US); A61K31/513 (EP,US); A61K31/555 (EP,US);
A61K31/7068 (EP,KR,US); A61K33/24 (KR); A61K33/243 (EP,US);
A61K38/08 (EP,KR,US); A61K38/185 (EP,KR,US); A61K41/0038 (KR);
A61K45/06 (EP,KR,US); A61N5/10 (US); A61N5/1001 (US);
A61P1/04 (EP); A61P1/16 (EP); A61P1/18 (EP);
A61P11/00 (EP); A61P13/08 (EP); A61P13/10 (EP);
A61P13/12 (EP); A61P15/00 (EP); A61P17/00 (EP);
A61P19/00 (EP); A61P35/00 (EP); A61P35/02 (EP);
A61P43/00 (EP); A61K2300/00 (KR) (-)
C-Set:
A61K31/282, A61K2300/00 (EP,US);
A61K31/404, A61K2300/00 (EP,US);
A61K31/44, A61K2300/00 (EP,US);
A61K31/4745, A61K2300/00 (EP,US);
A61K31/506, A61K2300/00 (US,EP);
A61K31/513, A61K2300/00 (US,EP);
A61K31/555, A61K2300/00 (US,EP);
A61K31/7068, A61K2300/00 (EP,US);
A61K33/24, A61K2300/00 (US,EP);
A61K38/08, A61K2300/00 (US,EP);
A61K38/10, A61K2300/00 (US,EP);
A61K38/185, A61K2300/00 (US,EP)
(-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/06]
TitleGerman:CHEMOKINREZEPTORANTAGONIST UND DESSEN KOMBINATIONSTHERAPIE[2017/06]
English:CHEMOKINE RECEPTOR ANTAGONIST AND ITS COMBINATIONAL THERAPY[2017/06]
French:ANTAGONISTE DU RÉCEPTEUR DES CHIMIOKINES ET THÉRAPIE COMBINATOIRE LE COMPRENANT[2017/06]
Entry into regional phase16.09.2016National basic fee paid 
16.09.2016Search fee paid 
16.09.2016Designation fee(s) paid 
16.09.2016Examination fee paid 
Examination procedure16.09.2016Amendment by applicant (claims and/or description)
16.09.2016Examination requested  [2017/06]
16.09.2016Date on which the examining division has become responsible
03.07.2018Application deemed to be withdrawn, date of legal effect  [2019/01]
08.08.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2019/01]
Fees paidRenewal fee
16.09.2016Renewal fee patent year 03
28.02.2017Renewal fee patent year 04
29.01.2018Renewal fee patent year 05
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Documents cited:Search[Y]WO2011098762  (AFFITECH RES AS [NO], et al) [Y] 1-19 * the whole document * * page 85, lines 8-13 *;
 [XY]  - D. WONG ET AL, "Translating an Antagonist of Chemokine Receptor CXCR4: From Bench to Bedside", CLINICAL CANCER RESEARCH, US, (20081215), vol. 14, no. 24, doi:10.1158/1078-0432.CCR-07-4846, ISSN 1078-0432, pages 7975 - 7980, XP055422100 [X] 1,2,13,16-19 * the whole document * * page 7978 * [Y] 1-19

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-07-4846
 [XY]  - Ronnie Poon, "Blockade of therapy-induced acute recruitment of bone marrow-derived CXCR4+Flt-1+ hemangiocytes inhibits hypoxia-induced tumor angiogenesis in hepatocellular carcinoma", Cancer Research, (20080501), URL: http://cancerres.aacrjournals.org/content/68/9_Supplement/5323, (20171106), XP055422136 [X] 1,2,18,19 * abstract * [Y] 1-19
 [A]  - JAMES PEASE ET AL, "Chemokine Receptor Antagonists", JOURNAL OF MEDICINAL CHEMISTRY, (20121126), vol. 55, no. 22, doi:10.1021/jm300682j, ISSN 0022-2623, pages 9363 - 9392, XP055421895 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm300682j
 [A]  - J. A. GOODE ET AL, "Embolisation of cancer: what is the evidence?", CANCER IMAGING, (20040101), vol. 4, no. 2, doi:10.1102/1470-7330.2004.0021, pages 133 - 141, XP055421897 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1102/1470-7330.2004.0021
 [A]  - Sebastien Hotte, "Phase I/II study of CTCE-9908, a novel anticancer agent that inhibits CXCR4, in patients with advanced solid cancers", Molecular Cancer Therapeutics, (20071101), URL: http://mct.aacrjournals.org/content/6/11_Supplement/A153, (20171106), XP055422074 [A] 1-19 * the whole document *
 [A]  - ANDREW X. ZHU ET AL, "HCC and angiogenesis: possible targets and future directions", NATURE REVIEWS CLINICAL ONCOLOGY, NY, US, (20110308), vol. 8, no. 5, doi:10.1038/nrclinonc.2011.30, ISSN 1759-4774, pages 292 - 301, XP055422114 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1038/nrclinonc.2011.30
International search[X]WO9947158  (UNIV BRITISH COLUMBIA [CA], et al) [X] 1-19 * the abstract, claims 9, 11-14, 19-20, example 1 *;
 [X]WO0009152  (UNIV BRITISH COLUMBIA [CA], et al) [X] 1-19 * the abstract, claims 9, 11-15, 19-20 *;
 [A]US2011207814  (RAMESHWAR PRANELA [US]) [A] 1-19 * the whole document *;
 [X]WO2012047339  (GEN HOSPITAL CORP [US], et al) [X] 1, 3-18 * the abstract, description, paragraphs 14, 18, 24, 95 *;
 [A]WO2012058241  (UNIV SOUTH ALABAMA [US], et al) [A] 1-19* the whole document *;
 [X]CN103003306  (AFFITECH RES AS) [X] 1, 13, 16-18 * the abstract, claims 1, 49 *;
 [X]WO2013071068  (BRISTOL MYERS SQUIBB CO [US]) [X] 1, 3-18 * the abstract, claims 1-6, 10-11 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.