Extract from the Register of European Patents

EP Citations: EP2992891

Cited inSearch
Type:Non-patent literature
Publication information:[I]   ROGAWSKI ET AL: "Diverse mechanisms of antiepileptic drugs in the development pipeline", EPILEPSY RESEARCH, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 69, no. 3, 1 June 2006 (2006-06-01), pages 273 - 294, XP027974329, ISSN: 0920-1211, [retrieved on 20060601]
Type:Non-patent literature
Publication information:[Y]   STOEHR T ET AL: "The pre-clinical profile of the novel anticonvulsant lacosamide", EPILEPSIA, RAVEN PRESS LTD, NEW YORK, US, vol. 46, no. suppl. 6, 1 September 2005 (2005-09-01), pages 373 - 374, XP009092396, ISSN: 0013-9580
Type:Non-patent literature
Publication information:[Y]   HORSTMANN R ET AL: "SPM 927 DOES NOT INTERACT WITH VALPROIC ACID AND CARBAMAZEPINE", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 44, no. SUPPL. 09, 5 December 2003 (2003-12-05), pages 97, XP009028152, ISSN: 0161-5890
Type:Non-patent literature
Publication information:[Y]   MALAWSKA B ET AL: "BRIVARACETAM UCB", CURRENT OPINION IN INVESTIGATIONAL DRUGS, PHARMAPRESS, US, vol. 6, no. 7, 1 January 2005 (2005-01-01), pages 740 - 746, XP009055914, ISSN: 1472-4472
Type:Non-patent literature
Publication information:[Y]   KLITGAARD H: "ANTIEPILEPTIC DRUG DISCOVERY: LESSONS FROM THE PAST AND FUTURE CHALLENGES", ACTA NEUROLOGICA SCANDINAVICA. SUPPLEMENTUM, MUNKSGAARD, COPENHAGEN, DK, vol. 181, 1 January 2005 (2005-01-01), pages 68 - 72, XP009078178, ISSN: 0065-1427
Type:Non-patent literature
Publication information:[Y]   REYNOLDS E H ET AL: "SINGLE DRUG OR COMBINATION THERAPY OF EPILEPSY?", DRUGS, ADIS INTERNATIONAL LTD, NZ, vol. 21, no. 5, 1 January 1981 (1981-01-01), pages 374 - 382, XP009029147, ISSN: 0012-6667, DOI: 10.2165/00003495-198121050-00005
DOI: http://dx.doi.org/10.2165/00003495-198121050-00005
Cited inOpposition
Type:Patent literature
Publication No.:WO2006079547  
Type:Non-patent literature
Publication information:  JATUZIS D., ET AL: "Evaluation of the Effect of oral Lacosamide on concomitant AED Plasma Concentrations on Patients with partial Seizures", EPILEPSIA (AES PROCEEDINGS), vol. 46, no. 8, 1 January 2008 (2008-01-01), pages 170, XP055492673
Type:Non-patent literature
Publication information:  KWAN PATRICK, ET AL: "Combination Therapy in Epilepsy", DRUGS, vol. 66, 1 January 2006 (2006-01-01), pages 1817 - 1829, XP055803695
Type:Non-patent literature
Publication information:  MALAWSKA B, KULIG K: "BRIVARACETAM UCB", CURRENT OPINION IN INVESTIGATIONAL DRUGS, PHARMAPRESS, US, vol. 06, no. 07, 1 January 2005 (2005-01-01), US, pages 740 - 746, XP009055914, ISSN: 1472-4472
Type:Non-patent literature
Publication information:  ANONYMOUS: "UCB ANNOUNCES PROPOSED ACQUISITION OF SCHWARZ PHARMA FOR CASH AND SHARES, VALUING SCHWARZ PHARMA AT 4.4 BILLION EUROS BUILDING THE NEXT GENERATION GLOBAL BIOPHARMACEUTICAL LEADER", UCB PRESS RELEASE, 25 September 2006 (2006-09-25), pages 1 - 7, XP055803700, Retrieved from the Internet [retrieved on 20210511]
Cited inby applicant
Type:Patent literature
Publication No.:US5378729  
Type:Patent literature
Publication No.:US5773475  
Type:Patent literature
Publication No.:EP1541138  
Type:Patent literature
Publication No.:EP2005010603  
Type:Non-patent literature
Publication information:  J. MARCH: "Advanced Organic Chemistry", 1985, JOHN WILEY AND SONS, pages: 16 - 18
Type:Non-patent literature
Publication information:  LOSCHER, W.; NOLTING, B.: "The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. IV. Protective indices", EPILEPSY RES, vol. 9, 1991, pages 1 - 10, XP024394354, DOI: doi:10.1016/0920-1211(91)90041-D
DOI: http://dx.doi.org/10.1016/0920-1211(91)90041-D
Type:Non-patent literature
Publication information:  LUSZCZKI JJ; BOROWICZ KK; SWIADER M; CZUCZWAR SJ: "Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis", EPILEPSIA, vol. 44, 2003, pages 489 - 99
Type:Non-patent literature
Publication information:  BARTON, M.E.; KLEIN, B.D.; WOLF, H.H.; WHITE, H.S: "Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy", EPILEPSY RES., vol. 47, 2001, pages 217 - 227, XP055090437, DOI: doi:10.1016/S0920-1211(01)00302-3
DOI: http://dx.doi.org/10.1016/S0920-1211(01)00302-3
Type:Non-patent literature
Publication information:  BERENBAUM, M.C.: "What is synergy?", PHARMACOL REV, vol. 41, 1989, pages 93 - 141, XP002105789
Type:Non-patent literature
Publication information:  BIALER, M.; JOHANNESSEN, S.I.; KUPFERBERG, H.J.; LEVY, R.H.; LOISEAU, P.; PERUCCA, E.: "Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V", EPILEPSY RESEARCH, vol. 43, 2001, pages 11 - 58
Type:Non-patent literature
Publication information:  BIALER, M.; JOHANNESSEN, S.I.; KUPFERBERG, H.J.; LEVY, R.H.; LOISEAU, P.; PERUCCA, E.: "Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI", EPILEPSY RESEARCH, vol. 51, 2002, pages 31 - 71, XP002274395, DOI: doi:10.1016/S0920-1211(02)00106-7
DOI: http://dx.doi.org/10.1016/S0920-1211(02)00106-7
Type:Non-patent literature
Publication information:  BIALER, M.; JOHANNESSEN, S.I.; KUPFERBERG, H.J.; LEVY, R.H.; PERUCCA, E.; TORBJORN, T.: "Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII", EPILEPSY RESEARCH, vol. 61, 2004, pages 1 - 48, XP004579931, DOI: doi:10.1016/j.eplepsyres.2004.07.010
DOI: http://dx.doi.org/10.1016/j.eplepsyres.2004.07.010
Type:Non-patent literature
Publication information:  BOROWICZ, K.K.; KLEINROK, Z.; CZUCZWAR, S.J.: "The AMPA/kainate receptor antagonist, LY 300164, increases the anticonvulsant effects of diazepam", NAUNYN SCHMIEDEBERGS ARCH PHARMACOL, vol. 361, 2000, pages 629 - 35
Type:Non-patent literature
Publication information:  BOROWICZ, K.K.; SWIADER, M.; LUSZCZKI, J.; CZUCZWAR, S.J.: "Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis", EPILEPSIA, vol. 43, 2002, pages 956 - 963
Type:Non-patent literature
Publication information:  BOURGEOIS, B.F.D.: "Anticonvulsant potency and neurotoxicity of valproate alone and in combination with carbamazepine and phenobarbital", CLIN NEUROPHARMACOL, vol. 11, 1988, pages 348 - 59
Type:Non-patent literature
Publication information:  BOURGEOIS, B.F.D.; WAD, N.: "Combined administration of carbamazepine and phenobarbital: effect on anticonvulsant activity and neurotoxicity", EPILEPSIA, vol. 29, 1988, pages 482 - 7
Type:Non-patent literature
Publication information:  BRODIE, M.J.: "Do we need any more new antiepileptic drugs?", EPILEPSY RES, vol. 45, 2001, pages 3 - 6
Type:Non-patent literature
Publication information:  DECKERS, C.L.P.; CZUCZWAR, S.J.; HEKSTER, Y.A. ET AL.: "Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed", EPILEPSIA, vol. 41, 2000, pages 1364 - 1374, XP009035157, DOI: doi:10.1111/j.1528-1157.2000.tb00111.x
DOI: http://dx.doi.org/10.1111/j.1528-1157.2000.tb00111.x
Type:Non-patent literature
Publication information:  DUNHAM, N.W.; MIYA, T.S.: "A note on a simple apparatus for detecting neurological deficit in rats and mice", J. AM. PHARM. ASSOC., vol. 46, 1957, pages 208 - 209
Type:Non-patent literature
Publication information:  GOWER, A.J.; NOYER, M.; VERLOES, R. ET AL.: "Ucb L059, a novel anticonvulsant drug: pharmacological profile in animals", EUR J PHARMACOL, vol. 222, 1992, pages 193 - 203
Type:Non-patent literature
Publication information:  EUR J PHARMACOL, vol. 230, 1993, pages 389
Type:Non-patent literature
Publication information:  HOVINGA, C.A.: "Erlosamide Schwarz Pharma", IDRUGS, vol. 6, no. 5, 2003
Type:Non-patent literature
Publication information:  KERRY, D.W.; HAMILTON-MILLER, J.M.T.; BRUMFITT, W: "Trimethoprim and rifampicin: in vitro activities separately and in combination", J ANTIMICROB CHEMOTHER, vol. 1, 1975, pages 417 - 27
Type:Non-patent literature
Publication information:  KLITGAARD, H.; MATAGNE, A.; GOBERT, J. ET AL.: "Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy", EUR J PHARMACOL, vol. 353, 1998, pages 191 - 206, XP000910515, DOI: doi:10.1016/S0014-2999(98)00410-5
DOI: http://dx.doi.org/10.1016/S0014-2999(98)00410-5
Type:Non-patent literature
Publication information:  KRAMER, G.: "The limitations of antiepileptic drug monotherapy", EPILEPSIA, vol. 38, no. 5, 1997, pages S9 - S13
Type:Non-patent literature
Publication information:  LITCHFIELD, J.T.; WILCOXON, F.: "A simplified method of evaluating dose-effect experiments", J. PHARMACOL EXP THER, vol. 96, 1949, pages 99 - 113
Type:Non-patent literature
Publication information:  LOISEAU, P.: "DO we need novel anti-epileptic drugs?", BR. J. CLIN. PRACT., vol. 42, 1988, pages 2 - 3
Type:Non-patent literature
Publication information:  LOSCHER, W.; HONACK, D.: "Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats", EUR J PHARMACOL, vol. 232, 1993, pages 147 - 158, XP023770418, DOI: doi:10.1016/0014-2999(93)90768-D
DOI: http://dx.doi.org/10.1016/0014-2999(93)90768-D
Type:Non-patent literature
Publication information:  LUSZCZKI, J.J.; ANDRES, M.M.; CZUCZWAR, P.; CIOCZEK-CZUCZWAR, A.; RATNARAJ, N.; PATSALOS, P.N.; CZUCZWAR S.J.: "Pharmacodynamic and pharmacokinetic characterization of interactions between Levetiracetam and numerous antiepileptic drugs in the mouse maximal electroshock seizure model: an isobolographical analysis", EPILEPSIA, vol. 47, 2006, pages 10 - 20, XP055492666
DOI: http://dx.doi.org/10.1111/j.1528-1167.2006.00364.x
Type:Non-patent literature
Publication information:  LUSZCZKI, J.J.; CZUCZWAR, M.; KIS, J.; KRYSA, J.; PASZTELAN, I.; SWIADER, M.; CZUCZWAR, S.J.: "Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis", EPILEPSIA, vol. 44, no. 8, 2003, pages 1003 - 1013, XP055492662
DOI: http://dx.doi.org/10.1046/j.1528-1157.2003.10003.x
Type:Non-patent literature
Publication information:  LUSZCZKI, J.J.; CZUCZWAR, S.J.: "Isobolographic and subthreshold methods in the detection of interactions between oxcarbazepine and conventional antiepileptics - a comparative study", EPILEPSY RES., vol. 56, 2003, pages 27 - 42
Type:Non-patent literature
Publication information:  PATSALOS, P.N.: "Levetiracetam: pharmacology and therapeutics in the treatment of epilepsy and other neurological conditions", REV CONTEMP PHARMACOTHER, vol. 13, 2004, pages 1 - 168
Type:Non-patent literature
Publication information:  PORRECA, F.; JIANG, Q.; TALLARIDA, R.J.: "Modulation of morphine antinociception by peripheral [Leu5] enkephalin: a synergistic interaction", EUR J PHARMACOL, vol. 179, 1990, pages 463 - 468
Type:Non-patent literature
Publication information:  SANDER, J.W.A.S.; SHORVON, S.D.: "Incidence and prevalence studies in epilepsy and their methodological problems: a review", J. NEUROL. NEUROSURG. PHYCHIAT., vol. 50, 1987, pages 829 - 839
Type:Non-patent literature
Publication information:  SCHMIDT, D. AND MORSELLI, P.L.: "Intractable Epilepsy: Experimental and Clinical Aspects", 1986, RAVEN PRESS
Type:Non-patent literature
Publication information:  TALLARIDA, R.J.: "Statistical analysis of drug combinations for synergism", PAIN, vol. 49, 1992, pages 93 - 7, XP024379838, DOI: doi:10.1016/0304-3959(92)90193-F
DOI: http://dx.doi.org/10.1016/0304-3959(92)90193-F
Type:Non-patent literature
Publication information:  TALLARIDA, R.J.; STONE, D.J.; MCCARY, J.D. ET AL.: "Response surface analysis of synergism between morphine and clonidine", J PHARMACOL EXP THER, vol. 289, 1999, pages 8 - 13
Type:Non-patent literature
Publication information:  TALLARIDA, R.J.; STONE, D.J.; RAFFA, R.B.: "Efficient designs for studying synergistic drug combinations", LIFE SCI, vol. 61, 1997, pages PL417 - 25
Type:Non-patent literature
Publication information:  TALLARIDA, R.J.: "The interaction index: a measure of drug synergism", PAIN, vol. 98, 2002, pages 163 - 8, XP055071866, DOI: doi:10.1016/S0304-3959(02)00041-6
DOI: http://dx.doi.org/10.1016/S0304-3959(02)00041-6
Type:Non-patent literature
Publication information:  WARNER, T.; PATSALOS, P.N.; PREVETT, M. ET AL.: "Lamotrigine-induced carbamazepine toxicity: an interaction with carbamazepine-10,11 -epoxide", EPILEPSY RES, vol. 11, 1992, pages 147 - 50, XP024394370, DOI: doi:10.1016/0920-1211(92)90049-Y
DOI: http://dx.doi.org/10.1016/0920-1211(92)90049-Y