EP2927213 - Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 20.09.2019 Database last updated on 03.09.2024 | |
Former | The patent has been granted Status updated on 12.10.2018 | ||
Former | Grant of patent is intended Status updated on 17.05.2018 | ||
Former | Examination is in progress Status updated on 02.12.2016 | Most recent event Tooltip | 20.09.2019 | No opposition filed within time limit | published on 23.10.2019 [2019/43] | Applicant(s) | For all designated states Amgen Inc. One Amgen Center Drive M/S 28-2-C Thousand Oaks, CA 91320 / US | [2015/41] | Inventor(s) | 01 /
Bartberger, Michael David 4471 Ventura Canyon Avenue D-105 Sherman Oaks, CA 91423 / US | 02 /
Gonzalez Buenrostro, Ana 419 Turner Terrace Apt. 9 San Mateo, CA 94401 / US | 03 /
Beck, Hilary Plake 115 Springdale Way Emerald Hills, CA 94062 / US | 04 /
Chen, Xiaoqi 970 Blair Court Palo Alto, CA 94303 / US | 05 /
Connors, Richard Victor 935 Crespi Drive Pacifica, CA 94044 / US | 06 /
Deignan, Jeffery 860 Head Street San Francisco, CA 94132 / US | 07 /
Duquette, Jason 460 Bayview Avenue Millbrae, CA 90403 / US | 08 /
Eksterowicz, John 1845 Church Street San Francisco, CA 94131 / US | 09 /
Fisher, Benjamin 1020 Yates Way Apt. 313 San Mateo, CA 94403 / US | 10 /
Fox, Brian Matthew 124 Swallowtail Court Brisbane, CA 94005 / US | 11 /
Fu, Jiasheng 221 Pelican Court Foster City, CA 94404 / US | 12 /
Fu, Zice 788 Santa Maria Lane Foster City, CA 94404 / US | 13 /
Gonzalez Lopez de Turiso, Felix 241 Cardinal Medeiros Avenue Cambridge, MA 02141 / US | 14 /
Gribble, jr. Michael William 949 Capp Street Apt. 22 San Francisco, CA 94110 / US | 15 /
Gustin, Darin James 433 Kehoe Avenue Half Moon Bay, CA 94019 / US | 16 /
Heath, Julie Anne 6 Ivy Drive Orinda, CA 94563 / US | 17 /
Huang, Xin 16 Abbott Road Wellesly, MA 02481 / US | 18 /
Jiao, Xianjun 2603 All View Way Belmont, CA 94002 / US | 19 /
Johnson, Michael 409 Clipper Street San Francisco, CA 94114 / US | 20 /
Kayser, Frank 4150 17th Street, Apt. 25 San Francisco, CA 94114 / US | 21 /
Kopecky, David John 12067 Guerin Street, Unit 202 Studio City, CA 91604 / US | 22 /
Lai, SuJen 3 Rosewood Lane Natick, MA 01760 / US | 23 /
Li, Yihong 821 Taylor Boulevard Millbrae, CA 94030 / US | 24 /
Li, Zhihong 467 Anita Drive Millbrae, CA 94030 / US | 25 /
Liu, Jiwen 250 Trysail Court Foster City, CA 94404 / US | 26 /
Low, Jonathan Dante 19355 Sherman Way No. 39 Reseda, CA 91335 / US | 27 /
Lucas, Brian Stuart 4 Brantwood Road Arlington, MA 02476 / US | 28 /
Ma, Zhihua 12212 Campus Drive Lexington, MA 02421 / US | 29 /
McGee, Lawrence 39 Big Sur Way Pacifica, CA 94044 / US | 30 /
McIntosh, Joel 540 Fremont Avenue Pacifica, CA 94044 / US | 31 /
McMinn, Dustin 1065 Grand Teton Pacifica, CA 94044 / US | 32 /
Medina, Julio Cesar 2879 Roland Avenue San Carlos, CA 94070 / US | 33 /
Mihalic, Jeffrey Thomas 300 3rd Street 523 San Francisco, CA 94107 / US | 34 /
Olson, Steven Howard 406 Green Hills Drive Millbrae, CA 94030 / US | 35 /
Rew, Yosup 828 Juno Lane Foster City, CA 94404 / US | 36 /
Roveto, Philip Marley 921 Adams Street NE Albuquerque, NM 87110 / US | 37 /
Sun, Daqing 804 Cortez Lane Foster City, CA 94404 / US | 38 /
Wang, Xiaodong 821 Taylor Boulevard Millbrae, CA 94030 / US | 39 /
Wang, Yingcai 860 Helen Drive Millbrae, CA 94030 / US | 40 /
Yan, Xuelei 1120 Nimitz Lane Foster City, CA 94404 / US | 41 /
Yu, Ming 42 Williams Lane Foster City, CA 94404 / US | 42 /
Zhu, Jiang 747 Coastland Drive Palo Alto, CA 94303 / US | [2018/46] |
Former [2015/51] | 01 /
Bartberger, Michael David 4471 Ventura Canyon Avenue D-105 Sherman Oaks, CA 91423 / US | ||
02 /
Gonzalez Buenrostro, Ana 419 Turner Terrace Apt. 9 San Mateo, CA 94401 / US | |||
03 /
Beck, Hilary Plake 115 Springdale Way Emerald Hills, California 94062 / US | |||
04 /
Chen, Xiaoqi 970 Blair Court Palo Alto, CA 94303 / US | |||
05 /
Connors, Richard Victor 935 Crespi Drive Pacifica, CA 94044 / US | |||
06 /
Deignan, Jeffery 860 Head Street San Francisco, CA 94132 / US | |||
07 /
Duquette, Jason 460 Bayview Avenue Millbrae, CA 90403 / US | |||
08 /
Eksterowicz, John 1845 Church Street San Francisco, CA 94131 / US | |||
09 /
Fisher, Benjamin 1020 Yates Way Apt. 313 San Mateo, CA 94403 / US | |||
10 /
Fox, Brian Matthew 124 Swallowtail Court Brisbane, CA 94005 / US | |||
11 /
Fu, Jiasheng 221 Pelican Court Foster City, CA 94404 / US | |||
12 /
Fu, Zice 788 Santa Maria Lane Foster City, CA 94404 / US | |||
13 /
Gonzalez Lopez de Turiso, Felix 241 Cardinal Medeiros Avenue Cambridge, MA 02141 / US | |||
14 /
Gribble, jr. Michael William 949 Capp Street Apt. 22 San Francisco, CA 94110 / US | |||
15 /
Gustin, Darin James 433 Kehoe Avenue Half Moon Bay, CA 94019 / US | |||
16 /
Heath, Julie Anne 6 Ivy Drive Orinda, CA 94563 / US | |||
17 /
Huang, Xin 16 Abbott Road Wellesly, MA 02481 / US | |||
18 /
Jiao, Xianjun 2603 All View Way Belmont, CA 94002 / US | |||
19 /
Johnson, Michael 409 Clipper Street San Francisco, CA 94114 / US | |||
20 /
Kayser, Frank 4150 17th Street, Apt. 25 San Francisco, CA 94114 / US | |||
21 /
Kopecky, David John 12067 Guerin Street, Unit 202 Studio City, CA 91604 / US | |||
22 /
Lai, SuJen 3 Rosewood Lane Natick, MA 01760 / US | |||
23 /
Li, Yihong 821 Taylor Boulevard Millbrae, CA 94030 / US | |||
24 /
Li, Zhihong 467 Anita Drive Millbrae, CA 94030 / US | |||
25 /
Liu, Jiwen 250 Trysail Court Foster City, CA 94404 / US | |||
26 /
Low, Jonathan Dante 19355 Sherman Way No. 39 Reseda, CA 91335 / US | |||
27 /
Lucas, Brian Stuart 4 Brantwood Road Arlington, MA 02476 / US | |||
28 /
Ma, Zhihua 12212 Campus Drive Lexington, MA 02421 / US | |||
29 /
McGee, Lawrence 39 Big Sur Way Pacifica, CA 94044 / US | |||
30 /
McIntosh, Joel 540 Fremont Avenue Pacifica, CA 94044 / US | |||
31 /
McMinn, Dustin 1065 Grand Teton Pacifica, CA 94044 / US | |||
32 /
Medina, Julio Cesar 2879 Roland Avenue San Carlos, CA 94070 / US | |||
33 /
Mihalic, Jeffrey Thomas 300 3rd Street 523 San Francisco, CA 94107 / US | |||
34 /
Olson, Steven Howard 406 Green Hills Drive Millbrae, CA 94030 / US | |||
35 /
Rew, Yosup 828 Juno Lane Foster City, CA 94404 / US | |||
36 /
Roveto, Philip Marley 921 Adams Street NE Albuquerque, NM 87110 / US | |||
37 /
Sun, Daqing 804 Cortez Lane Foster City, CA 94404 / US | |||
38 /
Wang, Xiaodong 821 Taylor Boulevard Millbrae, CA 94030 / US | |||
39 /
Wang, Yingcai 860 Helen Drive Millbrae, CA 94030 / US | |||
40 /
Yan, Xuelei 1120 Nimitz Lane Foster City, CA 94404 / US | |||
41 /
Yu, Ming 42 Williams Lane Foster City, CA 94404 / US | |||
42 /
Zhu, Jiang 747 Coastland Drive Palo Alto, CA 94303 / US | |||
Former [2015/44] | 01 /
Bartberger, Michael David 4471 Ventura Canyon Avenue D-105 Sherman Oaks, CA 91423 / US | ||
02 /
Gonzalez Buenrostro, Ana 419 Turner Terrace Apt. 9 San Mateo, CA 94401 / US | |||
03 /
Beck, Hilary Plake 115 Springdale Way Emerald Hills, California 94062 / US | |||
04 /
Chen, Xiaoqi 970 Blair Court Palo Alto, CA 94303 / US | |||
05 /
Connors, Richard Victor 935 Crespi Drive Pacifica, CA 94044 / US | |||
06 /
Deignan, Jeffery 500 29th Street San Francisco, CA 94131 / US | |||
07 /
Duquette, Jason 460 Bayview Avenue Millbrae, CA 90403 / US | |||
08 /
Eksterowicz, John 1845 Church Street San Francisco, CA 94131 / US | |||
09 /
Fisher, Benjamin 1020 Yates Way Apt. 313 San Mateo, CA 94403 / US | |||
10 /
Fox, Brian Matthew 124 Swallowtail Court Brisbane, CA 94005 / US | |||
11 /
Fu, Jiasheng 221 Pelican Court Foster City, CA 94404 / US | |||
12 /
Fu, Zice 788 Santa Maria Lane Foster City, CA 94404 / US | |||
13 /
Gonzalez Lopez de Turiso, Felix 241 Cardinal Medeiros Avenue Cambridge, MA 02141 / US | |||
14 /
Gribble, jr. Michael William 949 Capp Street Apt. 22 San Francisco, CA 94110 / US | |||
15 /
Gustin, Darin James 433 Kehoe Avenue Half Moon Bay, CA 94019 / US | |||
16 /
Heath, Julie Anne 6 Ivy Drive Orinda, CA 94563 / US | |||
17 /
Huang, Xin 16 Abbott Road Wellesly, MA 02481 / US | |||
18 /
Jiao, Xianjun 2603 All View Way Belmont, CA 94002 / US | |||
19 /
Johnson, Michael 409 Clipper Street San Francisco, CA 94114 / US | |||
20 /
Kayser, Frank 4150 17th Street, Apt. 25 San Francisco, CA 94114 / US | |||
21 /
Kopecky, David John 12067 Guerin Street, Unit 202 Studio City, CA 91604 / US | |||
22 /
Lai, SuJen 3 Rosewood Lane Natick, MA 01760 / US | |||
23 /
Li, Yihong 821 Taylor Boulevard Millbrae, CA 94030 / US | |||
24 /
Li, Zhihong 467 Anita Drive Millbrae, CA 94030 / US | |||
25 /
Liu, Jiwen 250 Trysail Court Foster City, CA 94404 / US | |||
26 /
Low, Jonathan Dante 19355 Sherman Way No. 39 Reseda, CA 91335 / US | |||
27 /
Lucas, Brian Stuart 4 Brantwood Road Arlington, MA 02476 / US | |||
28 /
Ma, Zhihua 12212 Campus Drive Lexington, MA 02421 / US | |||
29 /
McGee, Lawrence 39 Big Sur Way Pacifica, CA 94044 / US | |||
30 /
McIntosh, Joel 540 Fremont Avenue Pacifica, CA 94044 / US | |||
31 /
McMinn, Dustin 1065 Grand Teton Pacifica, CA 94044 / US | |||
32 /
Medina, Julio Cesar 2879 Roland Avenue San Carlos, CA 94070 / US | |||
33 /
Mihalic, Jeffrey Thomas 300 3rd Street 523 San Francisco, CA 94107 / US | |||
34 /
Olson, Steven Howard 406 Green Hills Drive Millbrae, CA 94030 / US | |||
35 /
Rew, Yosup 828 Juno Lane Foster City, CA 94404 / US | |||
36 /
Roveto, Philip Marley 921 Adams Street NE Albuquerque, NM 87110 / US | |||
37 /
Sun, Daqing 804 Cortez Lane Foster City, CA 94404 / US | |||
38 /
Wang, Xiaodong 821 Taylor Boulevard Millbrae, CA 94030 / US | |||
39 /
Wang, Yingcai 860 Helen Drive Millbrae, CA 94030 / US | |||
40 /
Yan, Xuelei 1120 Nimitz Lane Foster City, CA 94404 / US | |||
41 /
Yu, Ming 42 Williams Lane Foster City, CA 94404 / US | |||
42 /
Zhu, Jiang 747 Coastland Drive Palo Alto, CA 94303 / US | Representative(s) | Hoffmann Eitle Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München / DE | [2015/41] | Application number, filing date | 15159363.9 | 03.06.2011 | [2015/41] | Priority number, date | US20100351827P | 04.06.2010 Original published format: US 351827 P | US20100352322P | 07.06.2010 Original published format: US 352322 P | US201161452578P | 14.03.2011 Original published format: US 201161452578 P | [2015/41] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2927213 | Date: | 07.10.2015 | Language: | EN | [2015/41] | Type: | B1 Patent specification | No.: | EP2927213 | Date: | 14.11.2018 | Language: | EN | [2018/46] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 23.07.2015 | Classification | IPC: | C07D211/40, C07D401/04, C07D401/06, C07D407/04, C07D407/06, C07D409/04, C07D413/06, C07D417/06, C07D471/20, C07D279/02, C07D401/12, C07D498/08, C07D498/20, A61K31/4412, A61P35/00 | [2015/41] | CPC: |
C07D211/76 (EP,IL,KR,US);
C07D211/40 (CN,IL);
A61K31/45 (IL);
A61K31/451 (KR);
A61P1/04 (EP,IL);
A61P29/00 (EP,IL);
A61P31/04 (EP,IL);
A61P31/12 (EP,IL);
A61P35/00 (EP,IL,KR);
A61P35/02 (EP,IL);
A61P43/00 (EP,IL);
C07D221/20 (EP,IL,US);
C07D279/02 (EP,CN,IL,US);
C07D401/04 (EP,CN,IL,US);
C07D401/06 (EP,CN,IL,KR,US);
C07D401/12 (EP,CN,IL,US);
C07D405/04 (EP,CN,IL,US);
C07D405/06 (CN,IL);
C07D405/12 (EP,CN,IL,US);
C07D407/04 (EP,IL,US);
C07D407/06 (EP,IL,US);
C07D409/04 (EP,CN,IL,US);
C07D409/12 (EP,CN,IL,US);
C07D413/06 (EP,CN,IL,KR,US);
C07D417/06 (EP,CN,IL,US);
C07D417/12 (EP,IL,US);
C07D417/14 (EP,IL,US);
C07D471/10 (EP,CN,IL,US);
C07D491/08 (EP,CN,IL,US);
C07D491/153 (EP,IL,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2016/17] |
Former [2015/41] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Extension states | BA | 18.03.2016 | ME | 18.03.2016 | Title | German: | Piperidinonderivate als MDM2-Hemmer zur Krebsbehandlung | [2015/41] | English: | Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer | [2015/41] | French: | Dérivés de pipéridone MDM2 utilisés comme inhibiteurs pour le traitement du cancer | [2015/41] | Examination procedure | 18.03.2016 | Examination requested [2016/17] | 31.03.2016 | Amendment by applicant (claims and/or description) | 02.08.2016 | Despatch of a communication from the examining division (Time limit: M06) | 13.02.2017 | Reply to a communication from the examining division | 16.05.2017 | Despatch of a communication from the examining division (Time limit: M06) | 02.01.2018 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 12.03.2018 | Reply to a communication from the examining division | 18.05.2018 | Communication of intention to grant the patent | 28.09.2018 | Fee for grant paid | 28.09.2018 | Fee for publishing/printing paid | 28.09.2018 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP11726581.9 / EP2576510 | Divisional application(s) | EP18197155.7 / EP3483143 | EP22160459.8 / EP4092012 | Opposition(s) | 15.08.2019 | No opposition filed within time limit [2019/43] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 12.03.2018 | Request for further processing filed | 12.03.2018 | Full payment received (date of receipt of payment) Request granted | 22.03.2018 | Decision despatched | Fees paid | Renewal fee | 17.03.2015 | Renewal fee patent year 03 | 17.03.2015 | Renewal fee patent year 04 | 10.06.2015 | Renewal fee patent year 05 | 10.06.2016 | Renewal fee patent year 06 | 16.06.2017 | Renewal fee patent year 07 | 27.06.2018 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AL | 14.11.2018 | [2019/26] | Documents cited: | Search | [I]WO2010028862 (PRIAXON AG [DE], et al) | by applicant | WO2007110649 | US7354944 | WO2008118455 | WO2008118454 | WO2008118468 | US2009023761 | US2009030002 | US2009054405 | US7514566 | US2009137581 | US2009163489 | WO2009085185 | US2009270445 | US7700636 | WO2010083246 | WO2010096314 | WO2010108074 | US2010273764 | WO2010132598 | WO2010151791 | WO2010151737 | WO2010151735 | WO2010151740 | US2010331293 | US2010331306 | US7897619 | US7919514 | US7919504 | US2011092504 | US2011097305 |