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EP2952524
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EP About this file: EP2952524
| EP2952524 - IMMUNOTHERAPY REGIMES DEPENDENT ON APOE STATUS [Right-click to bookmark this link] | Status | The application has been refused Status updated on 08.07.2022 Database last updated on 31.08.2024 | |
| Former | Examination is in progress Status updated on 28.04.2017 | Most recent event Tooltip | 08.07.2022 | Refusal of application | published on 10.08.2022 [2022/32] | Applicant(s) | For all designated states Janssen Sciences Ireland UC Eastgate Village, Eastgate Little Island, County Cork / IE | For all designated states Wyeth LLC 235 East 42nd Street New York, NY 10017 / US | [2015/50] | Inventor(s) | 01 /
Black, Ronald 2164 Fox Creek Road Berwyn, PA 19312 / US | 02 /
Ekman, Lars 213 Avenida Cortez La Jolla, CA 92037 / US | 03 /
Lieberburg, Ivan 85 Hillcrest Road Berkeley, CA 94705 / US | 04 /
Grundman, Michael 13236 Haxton Place San Diego, CA 92130 / US | 05 /
Callaway, James 4893 Drakewood Terrace San Diego, CA 92130 / US | 06 /
Gregg, Keith M. 17719 W. Wind Song Avenue Goodyear, AZ 85338 / US | 07 /
Jacobsen, Jack Steven 229 Mulberry Road Apt 6 Ramsey, NJ 07446 / US | 08 /
Gill, Davinder 20 Charlotte Drive Andover, MA 01810 / US | 09 /
Tchistiakova, Lioudmila 3 O'Grady Circle Stoneham, MA 01810 / US | 10 /
Widom, Angela 19 Cherokee Road Acton, MA 01720 / US | [2015/50] | Representative(s) | Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [2015/50] | Application number, filing date | 15161872.5 | 17.10.2008 | [2015/50] | Priority number, date | US20070999423P | 17.10.2007 Original published format: US 999423 P | US20080083827P | 25.07.2008 Original published format: US 83827 P | [2015/50] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2952524 | Date: | 09.12.2015 | Language: | EN | [2015/50] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 21.10.2015 | Classification | IPC: | C07K16/18, A61K39/00, C07K16/28 | [2015/50] | CPC: |
C07K16/18 (EP,CN,US);
A61P25/00 (EP);
A61P25/28 (EP);
A61P7/10 (EP);
A61P9/00 (EP);
C07K16/2896 (EP,US);
G06Q99/00 (EP,US);
A61K2039/505 (EP,US);
C07K2317/24 (EP,CN,US);
C07K2317/34 (EP,CN,US);
C07K2317/56 (EP,CN,US);
C07K2317/71 (EP,CN,US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2016/29] |
| Former [2015/50] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR | Extension states | AL | 09.06.2016 | BA | 09.06.2016 | MK | 09.06.2016 | RS | 09.06.2016 | Title | German: | VOM APOE-STATUS ABHÄNGIGE IMMUNTHERAPIEDOSIERUNGEN | [2015/50] | English: | IMMUNOTHERAPY REGIMES DEPENDENT ON APOE STATUS | [2015/50] | French: | RÉGIMES IMMUNOTHÉRAPEUTIQUES DÉPENDANT DU STATUT DE L'APOE | [2015/50] | Biological material | This application mentions deposited biological material, check the file for details | Examination procedure | 09.06.2016 | Amendment by applicant (claims and/or description) | 09.06.2016 | Examination requested [2016/29] | 03.05.2017 | Despatch of a communication from the examining division (Time limit: M06) | 29.09.2017 | Reply to a communication from the examining division | 06.12.2018 | Cancellation of oral proceeding that was planned for 11.12.2018 | 11.12.2018 | Date of oral proceedings (cancelled) | 05.02.2019 | Despatch of communication that the application is refused, reason: substantive examination [2022/32] | 30.06.2022 | Application refused, date of legal effect [2022/32] | Appeal following examination | 15.04.2019 | Appeal received No. T1898/19 | 12.06.2019 | Statement of grounds filed | 30.06.2022 | Result of appeal procedure: appeal of the applicant withdrawn | Parent application(s) Tooltip | EP08839961.3 / EP2207565 | Fees paid | Renewal fee | 31.03.2015 | Renewal fee patent year 03 | 31.03.2015 | Renewal fee patent year 04 | 31.03.2015 | Renewal fee patent year 05 | 31.03.2015 | Renewal fee patent year 06 | 31.03.2015 | Renewal fee patent year 07 | 12.10.2015 | Renewal fee patent year 08 | 11.10.2016 | Renewal fee patent year 09 | 11.10.2017 | Renewal fee patent year 10 | 11.10.2018 | Renewal fee patent year 11 | 15.10.2019 | Renewal fee patent year 12 | 14.10.2020 | Renewal fee patent year 13 | 29.09.2021 | Renewal fee patent year 14 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]US5624821 (WINTER GREGORY P [GB], et al) [A] 1-13* claims, in particular claim 4 table 1 *; | [A]WO2006031653 (WYETH CORP [US], et al) [A] 1-13 * figure 26B; example 5; sequence 88 *; | [Y]WO2006083689 (NEURALAB LTD, et al) [Y] 1-13 * page 1 - page 2; sequences 1,2 *; | [XY]US2006280743 (BASI GURIQ [US], et al) [X] 1-6,8-11,13 * examples, in particular example II, VI, VII; tables 7, 9A and 9B; paragraphs [0208], [0215] * [Y] 7,12; | [Y] - KINNECOM C ET AL, "Course of cerebral amyloid angiopathy?related inflammation", NEUROLOGY, LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, US, (20070401), vol. 68, no. 17, doi:10.1212/01.WNL.0000260066.98681.2E, ISSN 0028-3878, pages 1411 - 1416, XP008132668 [Y] 7,12 * paragraph bridging pages 1415-1416, reference 18 * DOI: http://dx.doi.org/10.1212/01.wnl.0000260066.98681.2e | [Y] - ARGARET M RACKE ET AL, "Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta", JOURNAL OF NEUROSCIENCE, THE SOCIETY, WASHINGTON, DC, US, (20050119), vol. 25, no. 3, doi:10.1523/JNEUROSCI.4337-04.2005, ISSN 1529-2401, pages 629 - 636, XP002660549 [Y] 7,12 * abstract figures * DOI: http://dx.doi.org/10.1523/jneurosci.4337-04.2005 | [Y] - MOUNT CLAIRE ET AL, "Alzheimer disease: progress or profit?", NATURE MEDICINE, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (20060701), vol. 12, no. 7, ISSN 1078-8956, pages 780 - 784, XP002620727 [Y] 7,12 * page 784, left-hand column * | [Y] - CHALMERS ET AL, "APOE epsilon 4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of A beta protein.", NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, (20030601), vol. 29, no. 3, ISSN 0305-1846, pages 231 - 238, XP055020648 [Y] 1-13 * page 232, column left * * reference 5 * DOI: http://dx.doi.org/10.1046/j.1365-2990.2003.00457.x | by applicant | EP0307434 | US4855283 | GB2220211 | EP0367166 | WO9007861 | EP0394827 | WO9014837 | WO9110741 | US5057540 | US5112946 | WO9213069 | WO9312227 | US5225539 | US5336603 | US5349053 | US5359046 | US5447851 | US5530101 | US5545806 | US5569825 | US5585089 | US5612486 | US5622929 | US5625126 | US5624821 | WO9717613 | WO9717614 | US5633425 | US5661016 | US5693762 | US5693761 | US5723125 | WO9823635 | US5770429 | US5783181 | US5789650 | WO9840100 | US5814318 | US5844095 | WO9906536 | US5874299 | US5877397 | US5908626 | WO0142306 | WO0200245 | WO0212553 | US6387674 | WO0246237 | US2002162129 | WO02088306 | WO02088307 | WO02096350 | WO03016467 | US2003068325 | US2003157579 | WO03070760 | US2003165496 | US6624821 | WO03077858 | US2004025363 | US2004038304 | US2004038317 | WO2004016282 | WO2004031400 | WO2004032868 | US2004082762 | US2004087777 | US6750324 | US2004132066 | US2004141984 | WO2004072266 | WO2004080419 | US2004213800 | EP1481008 | US2004241164 | US2004242845 | US2004247612 | WO2004108895 | US2004265308 | US2005008625 | WO2005012330 | WO2005028511 | US2005090648 | US2005118651 | US6906169 | US2005130266 | US2005142131 | WO2005065348 | WO2005069970 | US2005196399 | WO2005081872 | US2005255552 | WO2005123775 | WO2006003291 | WO2006006604 | WO2006005707 | WO2006036291 | US2006073158 | WO2006055778 | WO2006066089 | US2006134098 | US2006160184 | US2006165682 | WO2006081171 | US2006193850 | US2006198851 | WO2006118959 | US7135181 | US2006257396 | WO2006121656 | US2007020685 | US7195761 | US2007081998 | WO2007062088 | US2007134762 | US2007160616 | US2007166311 | WO2007113172 | US2007248606 | US2007281006 | US7318923 | US7320790 | US2008025988 | US7335478 | US7365168 | US2008145373 | - SELKOE, TINS, (1993), vol. 16, page 403 | - SELKOE, J. NEUROPATHOL. EXP. NEUROL., (1994), vol. 53, page 438 | - DUFF ET AL., NATURE, (1995), vol. 373, page 476 | - GAMES ET AL., NATURE, (1995), vol. 373, page 523 | - GOATE ET AL., NATURE, (1991), vol. 349, page 704 | - CHARTIER HARLAN ET AL., NATURE, (1991), vol. 353, page 844 | - MURRELL ET AL., SCIENCE, (1991), vol. 254, page 97 | - MULLAN ET AL., NATURE GENET., (1992), vol. 1, page 345 | - HARDY, TINS, (1997), vol. 20, page 154 | - SONGSIVILAI; LACHMANN, CLIN. EXP. IMMUNOL., (1990), vol. 79, pages 315 - 321 | - KOSTELNY ET AL., J. IMMUNOL., (1992), vol. 148, pages 1547 - 1553 | - Epitope Mapping Protocols in Methods in Molecular Biology, (1996), vol. 66 | - STAHLI ET AL., METHODS IN ENZYMOLOGY, (1983), vol. 9, page 242 | - KIRKLAND ET AL., J. IMMUNOL., (1986), vol. 137, page 3614 | - MOREL ET AL., MOL. IMMUNOL., (1988), vol. 25, no. 1, page 7 | - CHEUNG ET AL., VIROLOGY, (1990), vol. 176, page 546 | - MOLDENHAUER ET AL., SCAND. J. IMMUNOL., (1990), vol. 32, page 77 | - HARDY ET AL., TINS, (1997), vol. 20, pages 155 - 158 | - RAVETCH; KINET, ANNU. REV. IMMUNOL, (1991), vol. 9, pages 457 - 92 | - CAPEL ET AL., IMMUNOMETHODS, (1994), vol. 4, pages 25 - 34 | - DE HAAS ET AL., J. LAB. CLIN. MED., (1995), vol. 126, pages 330 - 41 | - GENOMICS, (1988), vol. 3, pages 373 - 379 | - J. BIOL. CHEM., (1984), vol. 259, pages 5495 - 5499 | - PROC. NATL. ACAD. SCI. U.S.A., (1985), vol. 82, pages 3445 - 3449 | - CORDER, SCIENCE, (1993), vol. 261, pages 921 - 3 | - FARRER, JAMA, (1997), vol. 278, pages 1349 - 56 | - SAUNDERS, NEUROLOGY, (1993), vol. 43, pages 1467 - 72 | - PEDIATRIC NEUROLOGY, vol. 20, no. 3, pages 241 - 243 | - AJNR, vol. 26, pages 825 - 830 | - NEJM, vol. 334, no. 8, pages 494 - 500 | - PEDIATR NEPHROL, vol. 18, pages 1161 - 1166 | - INTERNAL MEDICINE JOURNAL, vol. 35, pages 83 - 90 | - JNNP, vol. 68, pages 790 - 79 1 | - AJNR, vol. 23, pages 1038 - 1048 | - PAKJ MED SCI, vol. 21, no. 2, pages 149 - 154 | - AJNR, vol. 21, pages 1199 - 1209 | - QUEE ET AL., PROC. NATL. ACAD. SCI. USA, (1989), vol. 86, pages 10029 - 10033 | - NATURE, (1994), vol. 148, pages 1547 - 1553 | - NATURE BIOTECHNOLOGY, (1996), vol. 14, page 826 | - BLECK, BIOPROCESSING JOURNAL, (200509), page 1 | - ASAMI-OD ET AL., NEURODEGENERATIVE DISEASES, (2005), vol. 2, pages 36 - 43 | - RAVETCH; KINET, ANNU. REV. IMMUNOL., (1991), vol. 9, page 457 | - PARREN ET AL., J. IMMUNOL., (1992), vol. 148, page 695 | - J IMMUNOGEN, (1976), vol. 3, pages 357 - 362 | - LOGHEM, MONOGR ALLERGY, (1986), vol. 19, pages 40 - 51 | - CUNNINGHAM ET AL., J. BIOL. CHEM., (1970), vol. 9, page 3161 | - POWILLEIT ET AL., PLOS ONE, (2007), vol. 2, no. 5, page E415 | - ULRICH ET AL., INTERVIROLOGY, (1996), vol. 39, pages 126 - 132 | - LECHNER ET AL., INTERVIROLOGY, (2002), vol. 45, pages 212 - 217 | - KOLETZKI ET AL., J GEN VIR, (1997), vol. 78, pages 2049 - 2053 | - GRIFFITHS ET AL., J VIROL., (1993), vol. 67, no. 6, pages 3191 - 3198 | - ADAMS ET AL., NATURE, (1987), vol. 329, no. 3, pages 68 - 70 | - SEDLIK ET AL., PNAS, (1997), vol. 94, pages 7503 - 7508 | - WATANABE ET AL., J VIROL., (1996), vol. 76, no. 2, pages 767 - 773 | - BALL ET AL., GASTROENTEROLOGY, (1999), vol. 117, pages 40 - 48 | - SINIGAGLIA F. ET AL., NATURE, (1988), vol. 336, pages 778 - 780 | - CHICZ R.M. ET AL., J. EXP. MED., (1993), vol. 178, pages 27 - 47 | - HAMMER J. ET AL., CELL, (1993), vol. 74, pages 197 - 203 | - FALK K. ET AL., IMMUNOGENETICS, (1994), vol. 39, pages 230 - 242 | - SOUTHWOOD S. ET AL., J. IMMUNOLOGY, (1998), vol. 160, pages 3363 - 3373 | - STOUTE ET AL., N. ENGL. J. MED., (1997), vol. 336, pages 86 - 91 | - CHAN ET AL., ADVANCED DRUG DELIVERY REVIEWS, (1998), vol. 32, pages 173 - 186 | - LANGER, SCIENCE, (1990), vol. 249, page 1527 | - HANES, ADVANCED DRUG DELIVERY REVIEWS, (1997), vol. 28, page 97 | - HSIAO ET AL., SCIENCE, (1996), vol. 274, page 99 | - STAUFENBIEL ET AL., PROC. NATL. ACAD. SCI. USA, (1997), vol. 94, pages 13287 - 13292 | - STURCHLER-PIERRAT ET AL., PROC. NATL. ACAD. SCI. USA, (1997), vol. 94, pages 13287 - 13292 | - BORCHELT ET AL., NEURON, (1997), vol. 19, pages 939 - 945 | - RICHARDS ET AL., J. NEUROSCI., (2003), vol. 23, pages 8989 - 9003 | - CHENG, NAT MED., (2004), vol. 10, no. 11, pages 1190 - 2 | - TAKEUCHI ET AL., AMERICAN JOURNAL OF PATHOLOGY, (2000), vol. 157, pages 331 - 339 | - LAFERLA, NEURON, (2003), vol. 39, pages 409 - 421 | - FANSELOW, ANIM. LEARN. BEHAV., (1990), vol. 18, pages 264 - 270 | - WEHNER ET AL., NATURE GENET., (1997), vol. 17, pages 331 - 334 | - CALDARONE ET AL., NATURE GENET., (1997), vol. 17, pages 335 - 337 | - MANSOURI ET AL., INFECT. IMMUN., (1999), vol. 67, page 1461 | - GELINAS ET AL., AM J OCCUP THER, (1999), vol. 53, pages 471 - 81 | - ROSEN ET AL., AM J PSYCHIATRY, (1984), vol. 141, pages 1356 - 64 | - MCKHANN ET AL., NEUROLOGY, (1984), vol. 34, pages 939 - 44 | - FOLSTEIN ET AL., J PSYCH RES, (1975), vol. 12, pages 189 - 198 | - MORRIS, NEUROLOGY, (1993), vol. 43, pages 2412 - 2414 | - ROSEN ET AL., ANN NEUROL., (1980), vol. 17, pages 486 - 488 | - JOHNSON-WOOD ET AL., PROC. NATL. ACAD. SCI., USA, (1997), vol. 94, pages 1550 - 55 | - IDUSOGIE ET AL., J. IMMUNOL., (2000), vol. 164, pages 4178 - 4184 | - PHILLIPS ET AL., CANCER RES., (2000), vol. 60, pages 6977 - 84 | - APRILE ET AL., CLIN. EXP. IMMUNOL., (1981), vol. 46, pages 565 - 76 | WO2005US45614 | WO2007US09499 |