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Extract from the Register of European Patents

EP About this file: EP2952514

EP2952514 - N1/N2-LACTAM ACETYL-COA CARBOXYLASE INHIBITORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  28.07.2017
Database last updated on 03.10.2024
FormerExamination is in progress
Status updated on  14.04.2017
Most recent event   Tooltip28.07.2017Application deemed to be withdrawnpublished on 30.08.2017  [2017/35]
Applicant(s)For all designated states
Pfizer Inc.
235 East 42nd Street
New York, NY 10017 / US
[2015/50]
Inventor(s)01 / Bagley, Scott William
Pfizer Global Research and Development
Eastern Point Road
Groton, CT 06340 / US
02 / Dow, Robert Lee
Pfizer Global Research and Development
Eastern Point Road
Groton, CT 06340 / US
03 / Griffith, David Andrew
Pfizer Global Research and Development
87 Cambridge Park Drive
Cambridge, MA 02140 / US
04 / Smith, Aaron Christopher
Pfizer Global Research and Development
Eastern Point Road
Groton, CT 06340 / US
 [2015/50]
Representative(s)Pfizer
European Patent Department
23-25 avenue du Docteur Lannelongue
75668 Paris Cedex 14 / FR
[2015/50]
Application number, filing date15164071.118.10.2011
[2015/50]
Priority number, dateUS20100408127P29.10.2010         Original published format: US 408127 P
US201161531744P07.09.2011         Original published format: US 201161531744 P
[2015/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2952514
Date:09.12.2015
Language:EN
[2015/50]
Search report(s)(Supplementary) European search report - dispatched on:EP16.09.2015
ClassificationIPC:C07D471/20, C07D519/00, A61K31/435
[2015/50]
CPC:
C07D471/20 (EP,KR,US); A61K31/438 (KR); A61P1/16 (EP);
A61P3/00 (EP); A61P3/04 (EP); A61P3/06 (EP);
A61P3/10 (EP); A61P43/00 (EP); A61P5/50 (EP);
A61P9/04 (EP); A61P9/10 (EP); A61P9/12 (EP);
C07D519/00 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/29]
Former [2015/50]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:N1/N2-LACTAM-ACETYL-COA-CARBOXYLASEHEMMER[2015/50]
English:N1/N2-LACTAM ACETYL-COA CARBOXYLASE INHIBITORS[2015/50]
French:INHIBITEURS DE LA N1/N2-LACTAME ACÉTYL-COA CARBOXYLASE[2015/50]
Examination procedure25.04.2016Amendment by applicant (claims and/or description)
09.06.2016Examination requested  [2016/29]
14.09.2016Despatch of a communication from the examining division (Time limit: M06)
25.03.2017Application deemed to be withdrawn, date of legal effect  [2017/35]
24.04.2017Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2017/35]
Parent application(s)   TooltipEP11784783.0  / EP2632925
Fees paidRenewal fee
17.08.2015Renewal fee patent year 03
17.08.2015Renewal fee patent year 04
02.11.2015Renewal fee patent year 05
31.10.2016Renewal fee patent year 06
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Documents cited:Search[IY]EP2123652  (TAKEDA PHARMACEUTICAL [JP]) [I] 1-11 * page 17, line 54; example 89; claim - * [Y] 1-11;
 [Y]WO2009144555  (PFIZER [US], et al) [Y] 1-11 * example 1; claim - *;
 [YP]WO2011058474  (PFIZER [US], et al) [YP] 1-11 * example -; claim - *;
 [YP]WO2011058473  (PFIZER [US], et al) [YP] 1-11* example -; claim - *
by applicantUS2002100
 WO03018586
 WO03072197
 WO03072578
 US6818658
 US2005267100
 WO2005116014
 WO2005116034
 US2006178501
 WO2007011809
 EP0901786
 WO2007122482
 WO2008065508
 WO2009016462
 WO2009144554
 WO2009144555
 WO2010013161
 WO2010023594
 WO2010086820
 WO2010103437
 WO2010103438
 WO2010106457
 WO2010128425
 WO2010128414
 WO2010140092
 WO2011005611
    - ABU-ETHEIGA, L. ET AL., "Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets", PNAS, (2003), vol. 100, no. 18, pages 10207 - 10212
    - CHOI, C.S. ET AL., "Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity", PNAS, (2007), vol. 104, no. 42, pages 16480 - 16485
    - SAVAGE, D.B. ET AL., "Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2", J CLIN INVEST
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    - BERGE ET AL., J. PHARM. SCI., (1977), vol. 66, pages 1 - 19
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    - ZIMMET, P.Z. ET AL., "The Metabolic Syndrome: Perhaps an Etiologic Mystery but Far From a Myth - Where Does the International Diabetes Federation Stand?", DIABETES & ENDOCRINOLOAV, (2005), vol. 7, no. 2
    - ALBERTI, K.G. ET AL., "The Metabolic Syndrome - A New Worldwide Definition", LANCET, (2005), vol. 366, doi:doi:10.1016/S0140-6736(05)67402-8, pages 1059 - 62, XP025277749

DOI:   http://dx.doi.org/10.1016/S0140-6736(05)67402-8
    - ZHANG, S. ET AL., DRUG DISCOVERY TODAY, (2007), vol. 12, no. 9/10, pages 373 - 381
    - E.C. CHAO ET AL., NATURE REVIEWS DRUG DISCOVERY, (201007), vol. 9, pages 551 - 559
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    - JONES, R.M. ET AL., MEDICINAL CHEMISTRY, (2009), vol. 44, pages 149 - 170
    - KHARITONENKOV, A. ET AL., CURRENT OPINION IN INVESTIGATIONAL DRUGS, (2009), vol. 10, no. 4, pages 359 - 364
    - ZHONG, M., CURRENT TOPICS IN MEDICINAL CHEMISTRY, (2010), vol. 10, no. 4, pages 386 - 396
    - MEDINA, J.C., ANNUAL REPORTS IN MEDICINAL CHEMISTRY, (2008), vol. 43, pages 75 - 85
    - CARPINO, P.A.; GOODWIN, B., EXPERT OPIN. THER. PAT, (2010), vol. 20, no. 12, pages 1627 - 51
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.