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Extract from the Register of European Patents

EP About this file: EP2952501

EP2952501 - ANTI-CANCER DIBENZOCYCLOHEPTANE DERIVATIVES AND A CATALYTIC METHOD FOR DIBENZOCYCLOHEPTANE SYNTHESIS AND ALLOCOLCHICINOID SYNTHESIS [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  28.10.2016
Database last updated on 14.09.2024
Most recent event   Tooltip28.10.2016Withdrawal of applicationpublished on 30.11.2016  [2016/48]
Applicant(s)For all designated states
University of Windsor
401 Sunset Avenue
Windsor, Ontario N9B 3P4 / CA
[2015/50]
Inventor(s)01 / GREEN, James
3345 Maisonneuve Avenue
Windsor, Ontario N9E 1Y6 / CA
02 / MEHDI, Mariam
1227 Central Avenue
Windsor, Ontario N8Y 3V1 / CA
03 / DJURDJEVIC, Sinisa
2870 Askin Avenue
Windsor, Ontario N9E 3H9 / CA
 [2015/50]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstrasse 4
80802 München / DE
[2015/50]
Application number, filing date15170291.702.06.2015
[2015/50]
Priority number, dateUS201462007106P03.06.2014         Original published format: US 201462007106 P
[2015/50]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2952501
Date:09.12.2015
Language:EN
[2015/50]
Type: A3 Search report 
No.:EP2952501
Date:23.12.2015
[2015/52]
Search report(s)(Supplementary) European search report - dispatched on:EP25.11.2015
ClassificationIPC:C07C69/76, C07C43/295, C07C231/10, C07C233/23, C07C247/14, C07C49/255, C07C43/23, C07D317/70, C07D317/54
[2015/52]
CPC:
C07C233/52 (EP,US); C07C49/255 (US); A61P35/00 (EP);
C07C213/02 (US); C07C227/04 (US); C07C231/12 (US);
C07C233/23 (EP,US); C07C247/14 (US); C07C41/18 (US);
C07C41/30 (US); C07C43/23 (US); C07C43/295 (US);
C07C45/65 (US); C07C49/755 (EP,US); C07C49/84 (EP,US);
C07C67/313 (US); C07C67/333 (US); C07C67/343 (US);
C07C69/94 (EP,US); C07D317/54 (EP,US); C07D317/70 (EP,US);
C07C2603/32 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/30]
Former [2015/50]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:DIBENZOCYCLOHEPTAN-DERIVATE GEGEN KREBS UND KATALYTISCHES VERFAHREN ZUR DIBENZOCYCLOHEPTANSYNTHESE UND ALLOCOLCHICINOIDSYNTHESE[2015/51]
English:ANTI-CANCER DIBENZOCYCLOHEPTANE DERIVATIVES AND A CATALYTIC METHOD FOR DIBENZOCYCLOHEPTANE SYNTHESIS AND ALLOCOLCHICINOID SYNTHESIS[2015/51]
French:DIBENZOCYCLOHEPTANES COMME MEDICAMENT CONTRE CANCER ET PROCÉDÉ CATALYTIQUE DE SYNTHÈSE DE DIBENZOCYCLOHEPTANE ET DE SYNTHÈSE D'ALLOCOLCHICINOIDE[2015/52]
Former [2015/51]DIBENZOCYCLOHEPTANES COMME MÉDICAMENT CONTRE LE CANCER ET PROCÉDÉ CATALYTIQUE DE SYNTHÈSE DE DIBENZOCYCLOHEPTANE ET DE SYNTHÈSE D'ALLOCOLCHICINOIDE
Examination proceduredeletedCommunication of intention to grant the patent
15.06.2016Amendment by applicant (claims and/or description)
15.06.2016Examination requested  [2016/30]
25.10.2016Application withdrawn by applicant  [2016/48]
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Documents cited:Search[XI]  - KRISTEN LAROCQUE ET AL, "Novel Analogue of Colchicine Induces Selective Pro-Death Autophagy and Necrosis in Human Cancer Cells", PLOS ONE, (20140123), vol. 9, no. 1, doi:10.1371/journal.pone.0087064, page e87064, XP055207089 [X] 1-5,7 * page 2, column 2, paragraph 3; figure 1 * * abstract * [I] 1-7

DOI:   http://dx.doi.org/10.1371/journal.pone.0087064
 [XDA]  - SINISA DJURDJEVIC ET AL, "Intramolecular Nicholas Reactions in the Synthesis of Dibenzocycloheptanes. Synthesis of Allocolchicine NSC 51046 and Analogues and the Formal Synthesis of (-)-Allocolchicine", THE JOURNAL OF ORGANIC CHEMISTRY, (20101203), vol. 75, no. 23, doi:10.1021/jo101953n, ISSN 0022-3263, pages 8241 - 8251, XP055207032 [XD] 1-5 * page 8245; compounds 18e, 19e, 20e, 21 * * page 8250, column 2, paragraph l * * page 8241, column 1, paragraph 1 * * page 8244; table 2 * * page 8245; table 3 * * scheme 5; page 8245 * [A] 8-15

DOI:   http://dx.doi.org/10.1021/jo101953n
 [A]  - AMIT JANA ET AL, "Lateral Lithiation-Initiated Annulations in the Synthesis of 1-Oxygenated Carbazole Alkaloids and a Cycloheptacarbazole", SYNLETT, DE, (20120621), vol. 23, no. 12, doi:10.1055/s-0031-1290380, ISSN 0936-5214, pages 1769 - 1774, XP055228639 [A] 8-15 * scheme 9, compounds 40, 42, 43; page 1772 *

DOI:   http://dx.doi.org/10.1055/s-0031-1290380
by applicant   - DJURDJEVIC, S.; YANG, F.; GREEN, J. R., J ORG. CHEM., (2010), vol. 75, page 8241
    - DJURDJEVIC, S.; GREEN, J. R., ORG. LETT., (2007), vol. 9, page 5505
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.