EP2955222 - COMBINED CHEMICAL AND GENETIC APPROACHES FOR GENERATION OF INDUCED PLURIPOTENT STEM CELLS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 19.07.2019 Database last updated on 24.08.2024 | |
Former | The patent has been granted Status updated on 10.08.2018 | ||
Former | Grant of patent is intended Status updated on 27.03.2018 | ||
Former | Examination is in progress Status updated on 15.11.2016 | Most recent event Tooltip | 01.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 03.08.2022 [2022/31] | Applicant(s) | For all designated states The Scripps Research Institute Mail Drop TPC-8 10550 North Torrey Pines Road La Jolla CA 92037 / US | [2015/51] | Inventor(s) | 01 /
SHI, Yan No. 43, BoYaXiYuan Nongda Nan Road HaiDian Beijing 100094 / CN | 02 /
DESPONTS, Caroline 8746 Villa La Jolla Drive Unit 49 La Jolla, CA 92037 / US | 03 /
DING, Sheng 68 North Michigan Ave Unit 3 Pasadena, CA 91106 / US | 04 /
ZHOU, Hongyan 1326 3rd Avenue San Francisco, CA 94122 / US | 05 /
LIN, Tongxiang 4362 Clairemont Mesa Blvd. Apt. 52-1/2 San Diego, CA 92117 / US | 06 /
LI, Wenlin Department of Cell Biology Second Military Medical University 800 Xiangyin Road Shanghai 200433 / CN | 07 /
ZHU, Saiyong 4247 Nobel Drive Apt. 27 San Diego, CA 92122 / US | [2016/10] |
Former [2016/01] | 01 /
SHI, Yan No. 43, BoYaXiYuan Nongda Nan Road HaiDian Beijing 100094 / CN | ||
02 /
DESPONTS, Caroline 8746 Villa La Jolla Drive Unit 49 La Jolla, CA 92037 / US | |||
03 /
DING, Sheng 68 North Michigan Ave Unit 3 Pasadena, CA 91106 / US | |||
04 /
ZHOU, Hongyan 1326 Hongyan San Francisco, CA 94122 / US | |||
05 /
LIN, Tongxiang 4362 Clairemont Mesa Blvd. Apt. 52-1/2 San Diego, CA 92117 / US | |||
06 /
LI, Wenlin Department of Cell Biology Second Military Medical University 800 Xiangyin Road Shanghai 200433 / CN | |||
07 /
ZHU, Saiyong 4247 Nobel Drive Apt. 27 San Diego, CA 92122 / US | Representative(s) | J A Kemp LLP 80 Turnmill Street London EC1M 5QU / GB | [N/P] |
Former [2018/37] | J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB | ||
Former [2015/51] | Campbell, Patrick John Henry J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB | Application number, filing date | 15177122.7 | 17.03.2009 | [2015/51] | Priority number, date | US20080069956P | 17.03.2008 Original published format: US 69956 P | US20080197986P | 31.10.2008 Original published format: US 197986 P | [2015/51] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2955222 | Date: | 16.12.2015 | Language: | EN | [2015/51] | Type: | B1 Patent specification | No.: | EP2955222 | Date: | 12.09.2018 | Language: | EN | [2018/37] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 27.10.2015 | Classification | IPC: | C12N5/07 | [2018/14] | CPC: |
C12N5/0696 (EP,KR,US);
A61P1/16 (EP);
A61P1/18 (EP);
A61P11/00 (EP);
A61P11/06 (EP);
A61P11/08 (EP);
A61P13/12 (EP);
A61P17/00 (EP);
A61P17/02 (EP);
A61P25/00 (EP);
A61P25/28 (EP);
A61P3/10 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C12N15/85 (US);
C12N5/0602 (KR);
C12N5/0623 (KR);
C12N5/0625 (KR);
C12N5/0656 (KR);
C12N2500/14 (EP,US);
C12N2501/01 (EP,US);
C12N2501/065 (EP,US);
C12N2501/15 (EP,US);
C12N2501/602 (EP,US);
C12N2501/603 (EP,US);
C12N2501/604 (US);
C12N2501/605 (EP,US);
C12N2501/608 (EP,US);
C12N2501/727 (EP,US);
C12N2506/08 (EP,US);
C12N2506/094 (US);
C12N2506/1307 (US);
C12N2506/28 (US);
C12N2510/00 (EP,US)
(-)
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Former IPC [2015/51] | C12N5/00 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2016/30] |
Former [2015/51] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR | Title | German: | KOMBINIERTE CHEMISCHE UND GENETISCHE ANSÄTZE ZUR ERZEUGUNG VON INDUZIERTEN PLURIPOTENTEN STAMMZELLEN | [2015/51] | English: | COMBINED CHEMICAL AND GENETIC APPROACHES FOR GENERATION OF INDUCED PLURIPOTENT STEM CELLS | [2015/51] | French: | APPROCHES CHIMIQUES ET GÉNÉTIQUES COMBINÉES POUR LA GÉNÉRATION DE CELLULES SOUCHES PLURIPOTENTES INDUITES | [2015/51] | Examination procedure | 16.06.2016 | Amendment by applicant (claims and/or description) | 16.06.2016 | Examination requested [2016/30] | 14.07.2016 | Despatch of a communication from the examining division (Time limit: M04) | 14.11.2016 | Reply to a communication from the examining division | 17.01.2017 | Despatch of a communication from the examining division (Time limit: M04) | 07.02.2017 | Despatch of a communication from the examining division (Time limit: M04) | 07.02.2017 | Reply to a communication from the examining division | 21.06.2017 | Despatch of a communication from the examining division (Time limit: M06) | 28.11.2017 | Reply to a communication from the examining division | 28.03.2018 | Communication of intention to grant the patent | 27.07.2018 | Fee for grant paid | 27.07.2018 | Fee for publishing/printing paid | 27.07.2018 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP09721278.1 / EP2279243 | Divisional application(s) | EP18185585.9 / EP3409762 | Opposition(s) | 13.06.2019 | No opposition filed within time limit [2019/34] | Fees paid | Renewal fee | 16.07.2015 | Renewal fee patent year 03 | 16.07.2015 | Renewal fee patent year 04 | 16.07.2015 | Renewal fee patent year 05 | 16.07.2015 | Renewal fee patent year 06 | 16.07.2015 | Renewal fee patent year 07 | 10.03.2016 | Renewal fee patent year 08 | 10.03.2017 | Renewal fee patent year 09 | 13.03.2018 | Renewal fee patent year 10 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 17.03.2009 | AT | 12.09.2018 | CY | 12.09.2018 | CZ | 12.09.2018 | DK | 12.09.2018 | EE | 12.09.2018 | FI | 12.09.2018 | HR | 12.09.2018 | LT | 12.09.2018 | LV | 12.09.2018 | MC | 12.09.2018 | MK | 12.09.2018 | PL | 12.09.2018 | RO | 12.09.2018 | SI | 12.09.2018 | SK | 12.09.2018 | TR | 12.09.2018 | BG | 12.12.2018 | GR | 13.12.2018 | IS | 12.01.2019 | PT | 12.01.2019 | IE | 17.03.2019 | LU | 17.03.2019 | MT | 17.03.2019 | BE | 31.03.2019 | [2022/31] |
Former [2021/32] | HU | 17.03.2009 | |
AT | 12.09.2018 | ||
CY | 12.09.2018 | ||
CZ | 12.09.2018 | ||
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EE | 12.09.2018 | ||
FI | 12.09.2018 | ||
HR | 12.09.2018 | ||
LT | 12.09.2018 | ||
LV | 12.09.2018 | ||
MC | 12.09.2018 | ||
PL | 12.09.2018 | ||
RO | 12.09.2018 | ||
SI | 12.09.2018 | ||
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TR | 12.09.2018 | ||
BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
PT | 12.01.2019 | ||
IE | 17.03.2019 | ||
LU | 17.03.2019 | ||
MT | 17.03.2019 | ||
BE | 31.03.2019 | ||
Former [2021/26] | AT | 12.09.2018 | |
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TR | 12.09.2018 | ||
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GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
PT | 12.01.2019 | ||
IE | 17.03.2019 | ||
LU | 17.03.2019 | ||
MT | 17.03.2019 | ||
BE | 31.03.2019 | ||
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TR | 12.09.2018 | ||
BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
PT | 12.01.2019 | ||
IE | 17.03.2019 | ||
LU | 17.03.2019 | ||
MT | 17.03.2019 | ||
BE | 31.03.2019 | ||
Former [2020/17] | AT | 12.09.2018 | |
CZ | 12.09.2018 | ||
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EE | 12.09.2018 | ||
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MC | 12.09.2018 | ||
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RO | 12.09.2018 | ||
SI | 12.09.2018 | ||
SK | 12.09.2018 | ||
TR | 12.09.2018 | ||
BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
PT | 12.01.2019 | ||
IE | 17.03.2019 | ||
LU | 17.03.2019 | ||
BE | 31.03.2019 | ||
Former [2020/12] | AT | 12.09.2018 | |
CZ | 12.09.2018 | ||
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MC | 12.09.2018 | ||
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SI | 12.09.2018 | ||
SK | 12.09.2018 | ||
BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
PT | 12.01.2019 | ||
IE | 17.03.2019 | ||
LU | 17.03.2019 | ||
BE | 31.03.2019 | ||
Former [2020/09] | AT | 12.09.2018 | |
CZ | 12.09.2018 | ||
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BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
PT | 12.01.2019 | ||
IE | 17.03.2019 | ||
LU | 17.03.2019 | ||
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GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
PT | 12.01.2019 | ||
LU | 17.03.2019 | ||
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BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
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IS | 12.01.2019 | ||
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BG | 12.12.2018 | ||
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IS | 12.01.2019 | ||
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GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
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LT | 12.09.2018 | ||
LV | 12.09.2018 | ||
PL | 12.09.2018 | ||
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BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
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LV | 12.09.2018 | ||
BG | 12.12.2018 | ||
GR | 13.12.2018 | ||
IS | 12.01.2019 | ||
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HR | 12.09.2018 | ||
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LV | 12.09.2018 | ||
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Former [2019/07] | LT | 12.09.2018 | Documents cited: | Search | [A]GB2436737 (UNIV EDINBURGH [GB]) [A] 1-15 * claims 1, 31 *; | [E]WO2010077955 (SCRIPPS RESEARCH INST [US], et al) [E] 1-15* the whole document *; | [A] - WERNIG M ET AL, "In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state", NATURE, NATURE PUBLISHING GROUP, LONDON, GB, vol. 448, no. 7151, doi:10.1038/NATURE05944, ISSN 0028-0836, (20070719), pages 318 - 324, (20070606), XP002621304 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1038/NATURE05944 | [A] - TAKAHASHI K ET AL, "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors", CELL, CELL PRESS, CAMBRIDGE, NA, US, (20060825), vol. 126, no. 4, doi:10.1016/J.CELL.2006.07.024, ISSN 0092-8674, pages 663 - 676, XP003013968 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1016/j.cell.2006.07.024 | [A] - TETSUO WATABE ET AL, "TGF-beta reeptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells", THE JOURNAL OF CELL BIOLOGY : JCB, THE ROCKEFELLER UNIVERSITY PRESS, US, (20030101), vol. 163, no. 6, doi:10.1083/JCB.200305147, ISSN 0021-9525, pages 1303 - 1311, XP003016184 [A] 1-15 * abstract * DOI: http://dx.doi.org/10.1083/jcb.200305147 | [T] - PLEWS JORDAN R ET AL, "Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach.", PLOS ONE, (2010), vol. 5, no. 12, ISSN 1932-6203, pages 1 - 10, XP002635012 [T] 1,3-7,11,12 * the whole document * DOI: http://dx.doi.org/10.1371/JOURNAL.PONE.0014397 | [T] - H. ZHOU ET AL, "Conversion of Mouse Epiblast Stem Cells to an Earlier Pluripotency State by Small Molecules", JOURNAL OF BIOLOGICAL CHEMISTRY, (20100924), vol. 285, no. 39, doi:10.1074/jbc.C110.150599, ISSN 0021-9258, pages 29676 - 29680, XP055052310 [T] 1-15 DOI: http://dx.doi.org/10.1074/jbc.C110.150599 | [XP] - LI WENLIN ET AL, "Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors", CELL STEM CELL, ELSEVIER, CELL PRESS, AMSTERDAM, NL, vol. 4, no. 1, doi:10.1016/J.STEM.2008.11.014, ISSN 1934-5909, (20090109), pages 16 - 19, (20081218), XP009139066 [XP] 1-15 * the whole document * DOI: http://dx.doi.org/10.1016/j.stem.2008.11.014 | by applicant | US4797368 | US5010175 | WO9119735 | WO9200091 | US5139941 | WO9320242 | US5288514 | US5384253 | US5506337 | US5519134 | US5525735 | US5539083 | US5549974 | US5569588 | US5580859 | US5589466 | US5593853 | US5656610 | US5702932 | US5736524 | US5780448 | US5789215 | US5945100 | US5981274 | US5994136 | US5994624 | US6013516 | US6030943 | US6534476 | US6696440 | US6703420 | US6730293 | WO2004045617 | US2005119203 | WO2005084158 | US2007134215 | US2007141703 | US2007172946 | US2007196919 | WO2007123667 | US2007254359 | US2007259423 | US2007264709 | US2007269412 | US2007281355 | US2008004287 | WO2008006583 | WO2008011093 | WO2008094597 | WO2008108741 | WO2008126932 | EP1992360 | - TAKAHASHI, K.; YAMANAKA, S., "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors", CELL, (2006), vol. 126, pages 663 - 676 | - OKITA, K.; ICHISAKA, T.; YAMANAKA, S, "Generation of germline-competent induced pluripotent stem cells", NATURE, (2007), vol. 448, pages 313 - 317 | - WEMIG, M. 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