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Extract from the Register of European Patents

EP About this file: EP2955222

EP2955222 - COMBINED CHEMICAL AND GENETIC APPROACHES FOR GENERATION OF INDUCED PLURIPOTENT STEM CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.07.2019
Database last updated on 24.08.2024
FormerThe patent has been granted
Status updated on  10.08.2018
FormerGrant of patent is intended
Status updated on  27.03.2018
FormerExamination is in progress
Status updated on  15.11.2016
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
The Scripps Research Institute
Mail Drop TPC-8 10550 North Torrey Pines Road
La Jolla CA 92037 / US
[2015/51]
Inventor(s)01 / SHI, Yan
No. 43, BoYaXiYuan
Nongda Nan Road
HaiDian
Beijing 100094 / CN
02 / DESPONTS, Caroline
8746 Villa La Jolla Drive
Unit 49
La Jolla, CA 92037 / US
03 / DING, Sheng
68 North Michigan Ave
Unit 3
Pasadena, CA 91106 / US
04 / ZHOU, Hongyan
1326 3rd Avenue
San Francisco, CA 94122 / US
05 / LIN, Tongxiang
4362 Clairemont Mesa Blvd.
Apt. 52-1/2
San Diego, CA 92117 / US
06 / LI, Wenlin
Department of Cell Biology
Second Military Medical University
800 Xiangyin Road
Shanghai 200433 / CN
07 / ZHU, Saiyong
4247 Nobel Drive
Apt. 27
San Diego, CA 92122 / US
 [2016/10]
Former [2016/01]01 / SHI, Yan
No. 43, BoYaXiYuan
Nongda Nan Road
HaiDian
Beijing 100094 / CN
02 / DESPONTS, Caroline
8746 Villa La Jolla Drive
Unit 49
La Jolla, CA 92037 / US
03 / DING, Sheng
68 North Michigan Ave
Unit 3
Pasadena, CA 91106 / US
04 / ZHOU, Hongyan
1326 Hongyan
San Francisco, CA 94122 / US
05 / LIN, Tongxiang
4362 Clairemont Mesa Blvd.
Apt. 52-1/2
San Diego, CA 92117 / US
06 / LI, Wenlin
Department of Cell Biology
Second Military Medical University
800 Xiangyin Road
Shanghai 200433 / CN
07 / ZHU, Saiyong
4247 Nobel Drive
Apt. 27
San Diego, CA 92122 / US
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2018/37]J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2015/51]Campbell, Patrick John Henry
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date15177122.717.03.2009
[2015/51]
Priority number, dateUS20080069956P17.03.2008         Original published format: US 69956 P
US20080197986P31.10.2008         Original published format: US 197986 P
[2015/51]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2955222
Date:16.12.2015
Language:EN
[2015/51]
Type: B1 Patent specification 
No.:EP2955222
Date:12.09.2018
Language:EN
[2018/37]
Search report(s)(Supplementary) European search report - dispatched on:EP27.10.2015
ClassificationIPC:C12N5/07
[2018/14]
CPC:
C12N5/0696 (EP,KR,US); A61P1/16 (EP); A61P1/18 (EP);
A61P11/00 (EP); A61P11/06 (EP); A61P11/08 (EP);
A61P13/12 (EP); A61P17/00 (EP); A61P17/02 (EP);
A61P25/00 (EP); A61P25/28 (EP); A61P3/10 (EP);
A61P9/00 (EP); A61P9/10 (EP); C12N15/85 (US);
C12N5/0602 (KR); C12N5/0623 (KR); C12N5/0625 (KR);
C12N5/0656 (KR); C12N2500/14 (EP,US); C12N2501/01 (EP,US);
C12N2501/065 (EP,US); C12N2501/15 (EP,US); C12N2501/602 (EP,US);
C12N2501/603 (EP,US); C12N2501/604 (US); C12N2501/605 (EP,US);
C12N2501/608 (EP,US); C12N2501/727 (EP,US); C12N2506/08 (EP,US);
C12N2506/094 (US); C12N2506/1307 (US); C12N2506/28 (US);
C12N2510/00 (EP,US) (-)
Former IPC [2015/51]C12N5/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/30]
Former [2015/51]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:KOMBINIERTE CHEMISCHE UND GENETISCHE ANSÄTZE ZUR ERZEUGUNG VON INDUZIERTEN PLURIPOTENTEN STAMMZELLEN[2015/51]
English:COMBINED CHEMICAL AND GENETIC APPROACHES FOR GENERATION OF INDUCED PLURIPOTENT STEM CELLS[2015/51]
French:APPROCHES CHIMIQUES ET GÉNÉTIQUES COMBINÉES POUR LA GÉNÉRATION DE CELLULES SOUCHES PLURIPOTENTES INDUITES[2015/51]
Examination procedure16.06.2016Amendment by applicant (claims and/or description)
16.06.2016Examination requested  [2016/30]
14.07.2016Despatch of a communication from the examining division (Time limit: M04)
14.11.2016Reply to a communication from the examining division
17.01.2017Despatch of a communication from the examining division (Time limit: M04)
07.02.2017Despatch of a communication from the examining division (Time limit: M04)
07.02.2017Reply to a communication from the examining division
21.06.2017Despatch of a communication from the examining division (Time limit: M06)
28.11.2017Reply to a communication from the examining division
28.03.2018Communication of intention to grant the patent
27.07.2018Fee for grant paid
27.07.2018Fee for publishing/printing paid
27.07.2018Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP09721278.1  / EP2279243
Divisional application(s)EP18185585.9  / EP3409762
Opposition(s)13.06.2019No opposition filed within time limit [2019/34]
Fees paidRenewal fee
16.07.2015Renewal fee patent year 03
16.07.2015Renewal fee patent year 04
16.07.2015Renewal fee patent year 05
16.07.2015Renewal fee patent year 06
16.07.2015Renewal fee patent year 07
10.03.2016Renewal fee patent year 08
10.03.2017Renewal fee patent year 09
13.03.2018Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU17.03.2009
AT12.09.2018
CY12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
MK12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
IE17.03.2019
LU17.03.2019
MT17.03.2019
BE31.03.2019
[2022/31]
Former [2021/32]HU17.03.2009
AT12.09.2018
CY12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
IE17.03.2019
LU17.03.2019
MT17.03.2019
BE31.03.2019
Former [2021/26]AT12.09.2018
CY12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
IE17.03.2019
LU17.03.2019
MT17.03.2019
BE31.03.2019
Former [2020/29]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
IE17.03.2019
LU17.03.2019
MT17.03.2019
BE31.03.2019
Former [2020/17]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
TR12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
IE17.03.2019
LU17.03.2019
BE31.03.2019
Former [2020/12]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
IE17.03.2019
LU17.03.2019
BE31.03.2019
Former [2020/09]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
IE17.03.2019
LU17.03.2019
Former [2020/01]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
LU17.03.2019
Former [2019/46]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
MC12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/37]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
PL12.09.2018
RO12.09.2018
SI12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/34]AT12.09.2018
CZ12.09.2018
DK12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
PL12.09.2018
RO12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/26]AT12.09.2018
CZ12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
PL12.09.2018
RO12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
PT12.01.2019
Former [2019/23]AT12.09.2018
CZ12.09.2018
EE12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
PL12.09.2018
RO12.09.2018
SK12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
Former [2019/22]CZ12.09.2018
FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
PL12.09.2018
RO12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
Former [2019/21]FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
BG12.12.2018
GR13.12.2018
IS12.01.2019
Former [2019/12]FI12.09.2018
HR12.09.2018
LT12.09.2018
LV12.09.2018
BG12.12.2018
GR13.12.2018
Former [2019/11]FI12.09.2018
HR12.09.2018
LT12.09.2018
BG12.12.2018
GR13.12.2018
Former [2019/08]FI12.09.2018
LT12.09.2018
Former [2019/07]LT12.09.2018
Documents cited:Search[A]GB2436737  (UNIV EDINBURGH [GB]) [A] 1-15 * claims 1, 31 *;
 [E]WO2010077955  (SCRIPPS RESEARCH INST [US], et al) [E] 1-15* the whole document *;
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DOI:   http://dx.doi.org/10.1038/NATURE05944
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DOI:   http://dx.doi.org/10.1016/j.cell.2006.07.024
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DOI:   http://dx.doi.org/10.1083/jcb.200305147
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DOI:   http://dx.doi.org/10.1371/JOURNAL.PONE.0014397
 [T]  - H. ZHOU ET AL, "Conversion of Mouse Epiblast Stem Cells to an Earlier Pluripotency State by Small Molecules", JOURNAL OF BIOLOGICAL CHEMISTRY, (20100924), vol. 285, no. 39, doi:10.1074/jbc.C110.150599, ISSN 0021-9258, pages 29676 - 29680, XP055052310 [T] 1-15

DOI:   http://dx.doi.org/10.1074/jbc.C110.150599
 [XP]  - LI WENLIN ET AL, "Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors", CELL STEM CELL, ELSEVIER, CELL PRESS, AMSTERDAM, NL, vol. 4, no. 1, doi:10.1016/J.STEM.2008.11.014, ISSN 1934-5909, (20090109), pages 16 - 19, (20081218), XP009139066 [XP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.stem.2008.11.014
by applicantUS4797368
 US5010175
 WO9119735
 WO9200091
 US5139941
 WO9320242
 US5288514
 US5384253
 US5506337
 US5519134
 US5525735
 US5539083
 US5549974
 US5569588
 US5580859
 US5589466
 US5593853
 US5656610
 US5702932
 US5736524
 US5780448
 US5789215
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 US5981274
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 WO2004045617
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 US2007269412
 US2007281355
 US2008004287
 WO2008006583
 WO2008011093
 WO2008094597
 WO2008108741
 WO2008126932
 EP1992360
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