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EP3037421
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EP About this file: EP3037421
| EP3037421 - MLK INHIBITORS AND METHODS OF USE [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 17.05.2019 Database last updated on 28.03.2026 | |
| Former | Examination is in progress Status updated on 27.10.2017 | ||
| Former | Request for examination was made Status updated on 02.06.2017 | Most recent event Tooltip | 17.05.2019 | Application deemed to be withdrawn | published on 19.06.2019 [2019/25] | Applicant(s) | For all designated states University of Rochester 601 Elmwood Avenue Box OTT Rochester, NY 14642 / US | [2016/26] | Inventor(s) | 01 /
GELBARD, Harris 601 Elmwood Ave, Box OTT Rochester, NY 14642 / US | 02 /
DEWHURST, Stephen 601 Elmwood Ave, Box OTT Rochester, NY 14642 / US | 03 /
GOODFELLOW, Val, S. 601 Elmwood Ave, Box OTT Rochester, NY 14642 / US | 04 /
WIEMANN, Torsten 601 Elmwood Ave, Box OTT Rochester, NY 14642 / US | 05 /
LOWETH, Colin 1714 Weatherwood Court San Marco, CA 92078 / US | [2016/26] | Representative(s) | Dehns 10 Old Bailey London EC4M 7NG / GB | [N/P] |
| Former [2016/26] | Gordon, Jennifer Claire Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD / GB | Application number, filing date | 15186751.2 | 25.11.2009 | [2016/26] | Priority number, date | US20080117950P | 25.11.2008 Original published format: US 117950 P | US20090148755P | 30.01.2009 Original published format: US 148755 P | US20090148778P | 30.01.2009 Original published format: US 148778 P | [2016/26] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP3037421 | Date: | 29.06.2016 | Language: | EN | [2016/32] | Type: | A3 Search report | No.: | EP3037421 | Date: | 30.11.2016 | Language: | EN | [2016/48] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 31.10.2016 | Classification | IPC: | C07D471/04, C07D487/04, A61P25/00, A61K31/437, A61K45/06 | [2016/26] | CPC: |
A61K31/437 (EP,US);
A61K31/438 (EP,US);
A61K31/444 (EP,US);
A61K31/496 (EP,US);
A61K31/4985 (EP,US);
A61K31/506 (EP,US);
A61K31/5377 (EP,US);
A61K31/553 (EP,US);
A61K45/06 (EP,US);
A61P1/04 (EP);
A61P1/16 (EP);
A61P13/12 (EP);
A61P19/02 (EP);
A61P19/06 (EP);
A61P19/08 (EP);
A61P25/00 (EP);
A61P25/04 (EP);
A61P25/16 (EP);
A61P25/18 (EP);
A61P25/24 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P27/16 (EP);
A61P29/00 (EP);
A61P3/00 (EP);
A61P3/04 (EP);
A61P3/06 (EP);
A61P3/08 (EP);
A61P3/10 (EP);
A61P35/00 (EP);
A61P37/02 (EP);
A61P43/00 (EP);
A61P5/50 (EP);
A61P7/10 (EP);
A61P9/00 (EP);
A61P9/04 (EP);
A61P9/10 (EP);
A61P9/12 (EP);
A61P9/14 (EP);
| C-Set: |
A61K31/437, A61K2300/00 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR [2017/27] |
| Former [2016/26] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR | Title | German: | MLK-HEMMER UND VERFAHREN ZUR VERWENDUNG | [2016/26] | English: | MLK INHIBITORS AND METHODS OF USE | [2016/26] | French: | INHIBITEURS DE MLK ET PROCÉDÉS D'UTILISATION | [2016/26] | Examination procedure | 24.09.2015 | Date on which the examining division has become responsible | 30.05.2017 | Amendment by applicant (claims and/or description) | 30.05.2017 | Examination requested [2017/27] | 26.10.2017 | Despatch of a communication from the examining division (Time limit: M06) | 04.05.2018 | Reply to a communication from the examining division | 07.09.2018 | Despatch of a communication from the examining division (Time limit: M04) | 18.01.2019 | Application deemed to be withdrawn, date of legal effect [2019/25] | 13.02.2019 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2019/25] | Parent application(s) Tooltip | EP09832359.5 / EP2379561 | Fees paid | Renewal fee | 24.09.2015 | Renewal fee patent year 03 | 24.09.2015 | Renewal fee patent year 04 | 24.09.2015 | Renewal fee patent year 05 | 24.09.2015 | Renewal fee patent year 06 | 30.11.2015 | Renewal fee patent year 07 | 28.11.2016 | Renewal fee patent year 08 | 27.11.2017 | Renewal fee patent year 09 | 27.11.2018 | Renewal fee patent year 10 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X] WO2008051493 (SIGNAL PHARM LLC et al.) | [X] WO2006063167 (SMITHKLINE BEECHAM CORP et al.) | [E] WO2010016490 (DAIICHI SANKYO CO LTD et al.) | [E] EP2308877 (DAIICHI SANKYO CO LTD et al.) | [X] WO2005028475 (VERTEX PHARMA et al.) | [X] WO2006036883 (JANSSEN PHARMACEUTICA NV et al.) | [X] WO2007106236 (SGX PHARMACEUTICALS INC et al.) | [X] WO2006015123 (SGX PHARMACEUTICALS INC et al.) | [X] WO2008124849 (SGX PHARMACEUTICALS INC et al.) | [X] WO2004078756 (EISAI LONDON RES LAB LTD et al.) | [E] WO2010059771 (OSI PHARM INC et al.) | [X] WO2005095400 (VERTEX PHARMA et al.) | [T] GALLO K A ET AL: "MIXED-LINEAGE KINASE CONTROL OF JNK AND P38 MAPK PATHWAYS", NATURE REVIEWS MOLECULAR CELL BIOLOGY, MACMILLAN MAGAZINES, LONDON, GB, vol. 3, no. 9, 1 September 2002 (2002-09-01), pages 663 - 672, XP008039578, DOI: 10.1038/NRM906 DOI: http://dx.doi.org/10.1038/nrm906 | by applicant | US6638521 | US6635680 | US6624200 | US6613361 | US6613358 | US6596308 | US6589563 | US6562375 | US6548084 | US6541020 | US6537579 | US6528080 | US6524621 | US6607751 | US6599529 | US6569463 | US6565883 | US6482440 | US6403597 | US6319919 | US6150354 | US6080736 | US5672356 | US5472704 | US5445829 | US5312817 | US5296483 | US6589549 | US6544548 | US6517864 | US6512010 | US6465006 | US6379696 | US6312717 | US6310177 | EGGERT, D.; GORANTLA, S.; POLUEKOVA, L.; DOU, H.; SCHIFITTO, G.; MAGGIRWAR, S.B.; DEWHURST, S.; GELBARD, H.A.; H.E. GENDELMAN: "Neuroprotective Activities of CEP-1347 in Models of HIV-1 Encephalitis", J. IMMUNOL. | KRISHNAN, V.; E. J. NESTLER, NATURE, vol. 455, 2008, pages 894 - 902 | WANG, L. H.; A. J. PADEN; E. M. JOHNSON, JR, J PHARMACOL EXP THER, vol. 312, 2005, pages 1007 - 19 | CONFORTI, P. ET AL., MOL CELL NEUROSCI, vol. 39, 2008, pages 1 - 7 | GENNARO,: "Remington: The Science and Practice of Pharmacy, 21st Ed.,", 2003, LIPPENCOTT WILLIAMS & WILKINS | TESTA, BERNARD AND MAYER, JOACHIM M.: "Hydrolysis in Drug and Prodrug Metabolism : Chemistry, Biochemistry, and Enzymology", 2003, WILEY-VHCA | INT. J. PHARM., vol. 115, 1995, pages 61 - 67 | T. HIGUCHI; V. STELLA: "Prodrugs as Novel Delivery Systems", ACS SYMPOSIUM SERIES, vol. 14, 1975 | H. BUNDGAARD: "Design of Prodrugs", 1985, ELSEVIER | EDWARD ROCHE,: "Bioreversible Carriers in Drug Design", 1987, AMERICAN PHARMACEUTICAL ASSOCIATION AND PERGAMON PRESS | STAHL, P. HEINRICH: "Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCHA | T. W. GREENE; P.G.M. WUTS: "Protective Groups in Organic Synthesis", 1999, WILEY | HUANG ET AL., DRUG DEV. IND. PHARM, vol. 29, 2003, pages 79 | PEARNCHOB ET AL., DRUG DEV. IND. PHARM., vol. 29, 2003, pages 925 | MAGGI ET AL., EUR. J. PHARM. BIOPHARM., vol. 55, 2003, pages 99 | KHANVILKAR ET AL., DRUG DEV. IND. PHARM., vol. 228, 2002, pages 601 | SCHMIDT ET AL., INT. J. PHARM., vol. 216, 2001, pages 9 | BRUNTON, LAZO AND PARKER,: "Goodman and Gilman's The Pharmacological Basis of Therapeutics, 11th Ed.,", 2006, MCGRAW-HILL | J. ORG. CHEM., 1995, pages 1565 - 1582 | PTERIDINES, vol. 13, 2002, pages 65 - 72 | D. EGGERT, JOURNAL OF IMMUNOLOGY, November 2009 (2009-11-01) |