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Extract from the Register of European Patents

EP About this file: EP3116546

EP3116546 - COMBINATION COMPRISING A BTK INHIBITOR AND AN AKT INHIBITOR [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  20.12.2019
Database last updated on 25.09.2024
FormerExamination is in progress
Status updated on  28.03.2019
FormerRequest for examination was made
Status updated on  16.12.2016
Most recent event   Tooltip20.12.2019Application deemed to be withdrawnpublished on 22.01.2020  [2020/04]
Applicant(s)For all designated states
Novartis AG
Lichtstrasse 35
4056 Basel / CH
[2017/03]
Inventor(s)01 / KUMAR, Rakesh
1250 South Collegeville Road
Collegeville, PA 19426 / US
02 / ROBELL, Kimberly A.
1250 South Collegeville Road
Collegeville, PA 19426 / US
 [2017/03]
Representative(s)Conroy, John
Fish & Richardson P.C.
Highlight Business Towers
Mies-van-der-Rohe-Straße 8
80807 München / DE
[N/P]
Former [2017/03]Rudge, Sewkian, et al
Novartis Pharma AG
Patent Department
4002 Basel / CH
Application number, filing date15708605.924.02.2015
[2017/03]
WO2015IB51380
Priority number, dateUS201461951640P12.03.2014         Original published format: US 201461951640 P
[2017/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015136398
Date:17.09.2015
Language:EN
[2015/37]
Type: A1 Application with search report 
No.:EP3116546
Date:18.01.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 17.09.2015 takes the place of the publication of the European patent application.
[2017/03]
Search report(s)International search report - published on:EP17.09.2015
ClassificationIPC:A61K45/06, A61K31/4155, A61K31/519, A61P35/00, A61P35/02
[2017/03]
CPC:
A61K31/519 (EP,CN,KR,US); A61K31/4155 (EP,CN,KR,US); A61K45/06 (EP,CN,KR,US);
A61P35/00 (EP); A61P35/02 (EP); A61P43/00 (EP);
A61K2300/00 (KR) (-)
C-Set:
A61K31/4155, A61K2300/00 (US,CN,EP);
A61K31/519, A61K2300/00 (CN,EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/03]
TitleGerman:KOMBINATION AUS EINEM BTK-INHIBITOR UND EINEM AKT-INHIBITOR[2017/03]
English:COMBINATION COMPRISING A BTK INHIBITOR AND AN AKT INHIBITOR[2017/03]
French:COMBINAISON COMPRENANT UN INHIBITEUR DE BTK ET UN INHIBITEUR D'ATK[2017/03]
Entry into regional phase12.10.2016National basic fee paid 
12.10.2016Designation fee(s) paid 
12.10.2016Examination fee paid 
Examination procedure07.09.2016Amendment by applicant (claims and/or description)
07.09.2016Date on which the examining division has become responsible
12.10.2016Examination requested  [2017/03]
01.04.2019Despatch of a communication from the examining division (Time limit: M04)
13.08.2019Application deemed to be withdrawn, date of legal effect  [2020/04]
09.09.2019Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2020/04]
Fees paidRenewal fee
10.02.2017Renewal fee patent year 03
14.02.2018Renewal fee patent year 04
27.02.2019Renewal fee patent year 05
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Cited inInternational search[A]WO2010088331  (GLAXOSMITHKLINE LLC [US], et al) [A] 1-26,53 * claims 1, 10, 21 *;
 [Y]  - AKINTUNDE AKINLEYE ET AL, "Ibrutinib and novel BTK inhibitors in clinical development", JOURNAL OF HEMATOLOGY & ONCOLOGY, BIOMED CENTRAL LTD, LONDON UK, (20130819), vol. 6, no. 1, doi:10.1186/1756-8722-6-59, ISSN 1756-8722, page 59, XP021162128 [Y] 1-26,53 * the whole document *

DOI:   http://dx.doi.org/10.1186/1756-8722-6-59
 [Y]  - SPENCER ANDREW ET AL, "Novel AKT Inhibitor GSK2110183 Shows Favorable Safety, Pharmacokinetics, and Clinical Activity in Multiple Myeloma. Preliminary Results From a Phase I First-Time-In-Human Study", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (201111), Database accession no. PREV201200219138, XP002738038 [Y] 1-26,53 * abstract *
    [ ] - BLOOD, 53RD ANNUAL MEETING AND EXPOSITION OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY (ASH); SAN DIEGO, CA, USA; DECEMBER 10 -13, 2011, (201111), vol. 118, no. 21, ISSN 0006-4971(print), page 808
 [A]  - JAIKRIT BHUTANI ET AL, "Akt inhibitors: mechanism of action and implications for anticancer therapeutics", INFECTIOUS AGENTS AND CANCER, BIOMED CENTRAL LTD, LO, (20131213), vol. 8, no. 1, doi:10.1186/1750-9378-8-49, ISSN 1750-9378, page 49, XP021171563 [A] 1-26,53 * the whole document *

DOI:   http://dx.doi.org/10.1186/1750-9378-8-49
by applicantUS5681835
 US5877219
 US6207716
 US6268391
 WO2008098104
 US7576209
 US2010197754
 WO2011152351
 WO2012020008
 WO2012156334
 WO2012170976
 US2013018032
 WO2013010869
 WO2013010380
 WO2013063401
 WO2013067260
 WO2013081016
 WO2013133367
 WO2013161848
 WO2013191965
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