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Extract from the Register of European Patents

EP About this file: EP3095796

EP3095796 - ANTI-HUMAN PROBDNF MONOCLONAL ANTIBODY, AND USES THEREOF IN PAINS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  03.09.2021
Database last updated on 02.09.2024
FormerThe patent has been granted
Status updated on  25.09.2020
FormerGrant of patent is intended
Status updated on  17.05.2020
FormerExamination is in progress
Status updated on  17.08.2018
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR
published on 17.07.2024  [2024/29]
Applicant(s)For all designated states
Shanghai Yile Biotechnology Limited
4F, Building 3
466 Yindu Road
Xuhui
Shanghai 200231 / CN
[2016/47]
Inventor(s)01 / WANG, Huamao
4F, Building 3
466 Yindu Road
Xuhui
Shanghai 200231 / CN
02 / DAI, Ruping
4F, Building 3
466 Yindu Road
Xuhui
Shanghai 200231 / CN
03 / LI, Zonghai
4F, Building 3
466 Yindu Road
Xuhui
Shanghai 200231 / CN
 [2016/51]
Former [2016/47]01 / WANG, Huamao
Rm 301 Building 6
333 Guiping Road
Xuhui
Shanghai 200233 / CN
02 / DAI, Ruping
Rm 301 Building 6
333 Guiping Road
Xuhui
Shanghai 200233 / CN
03 / LI, Zonghai
Rm 301 Building 6
333 Guiping Road
Xuhui
Shanghai 200233 / CN
Representative(s)Pfenning, Meinig & Partner mbB
Patent- und Rechtsanwälte
Theresienhöhe 11a
80339 München / DE
[2016/47]
Application number, filing date15737195.604.01.2015
[2016/47]
WO2015CN70011
Priority number, dateCN2014101589015.01.2014         Original published format: CN201410015890
[2016/47]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015106641
Date:23.07.2015
Language:ZH
[2015/29]
Type: A1 Application with search report 
No.:EP3095796
Date:23.11.2016
Language:EN
[2016/47]
Type: B1 Patent specification 
No.:EP3095796
Date:28.10.2020
Language:EN
[2020/44]
Search report(s)International search report - published on:CN23.07.2015
(Supplementary) European search report - dispatched on:EP24.10.2017
ClassificationIPC:C07K16/22, A61K39/00, A61P25/04, A61P29/00
[2020/21]
CPC:
C07K16/22 (EP,US); A61P25/04 (EP); A61P29/00 (EP);
A61K2039/505 (EP,US); C07K2317/24 (EP,US); C07K2317/565 (US);
C07K2317/92 (EP,US) (-)
Former IPC [2017/47]C07K16/22, C12N15/13, C12N15/63, A61K39/395, A61P25/04, A61K39/00
Former IPC [2016/47]C07K16/22, C12N15/13, C12N15/63, A61K39/395, A61P25/04
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2016/47]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:MONOKLONALER ANTIKÖRPER GEGEN MENSCHLICHEN PROBDNF UND VERWENDUNG DAVON BEI SCHMERZEN[2016/47]
English:ANTI-HUMAN PROBDNF MONOCLONAL ANTIBODY, AND USES THEREOF IN PAINS[2016/47]
French:ANTICORPS MONOCLONAL PROBDNF ANTIHUMAIN ET SES UTILISATIONS POUR DES DOULEURS[2016/47]
Entry into regional phase12.08.2016Translation filed 
12.08.2016National basic fee paid 
12.08.2016Search fee paid 
12.08.2016Designation fee(s) paid 
12.08.2016Examination fee paid 
Examination procedure12.08.2016Examination requested  [2016/47]
18.05.2018Amendment by applicant (claims and/or description)
16.08.2018Despatch of a communication from the examining division (Time limit: M04)
19.12.2018Reply to a communication from the examining division
02.05.2019Despatch of a communication from the examining division (Time limit: M04)
11.09.2019Reply to a communication from the examining division
18.05.2020Communication of intention to grant the patent
18.09.2020Fee for grant paid
18.09.2020Fee for publishing/printing paid
18.09.2020Receipt of the translation of the claim(s)
Opposition(s)29.07.2021No opposition filed within time limit [2021/40]
Fees paidRenewal fee
20.01.2017Renewal fee patent year 03
26.01.2018Renewal fee patent year 04
22.01.2019Renewal fee patent year 05
23.01.2020Renewal fee patent year 06
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU04.01.2015
AL28.10.2020
AT28.10.2020
CY28.10.2020
CZ28.10.2020
DK28.10.2020
EE28.10.2020
ES28.10.2020
FI28.10.2020
HR28.10.2020
IT28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
MK28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SI28.10.2020
SK28.10.2020
SM28.10.2020
TR28.10.2020
IE04.01.2021
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
IS28.02.2021
PT01.03.2021
[2024/29]
Former [2024/22]HU04.01.2015
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CZ28.10.2020
DK28.10.2020
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PL28.10.2020
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IE04.01.2021
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BE31.01.2021
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LI31.01.2021
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Former [2023/30]HU04.01.2015
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IE04.01.2021
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NO28.01.2021
GR29.01.2021
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CH31.01.2021
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IS28.02.2021
PT01.03.2021
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SI28.10.2020
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IE04.01.2021
LU04.01.2021
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NO28.01.2021
GR29.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
IS28.02.2021
PT01.03.2021
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IE04.01.2021
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NO28.01.2021
GR29.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
IS28.02.2021
PT01.03.2021
Former [2022/23]AL28.10.2020
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DK28.10.2020
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IT28.10.2020
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NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SI28.10.2020
SK28.10.2020
SM28.10.2020
IE04.01.2021
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
CH31.01.2021
LI31.01.2021
IS28.02.2021
PT01.03.2021
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IT28.10.2020
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MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SI28.10.2020
SK28.10.2020
SM28.10.2020
IE04.01.2021
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
CH31.01.2021
LI31.01.2021
PT01.03.2021
Former [2022/07]AL28.10.2020
AT28.10.2020
CZ28.10.2020
DK28.10.2020
EE28.10.2020
ES28.10.2020
FI28.10.2020
HR28.10.2020
IT28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SI28.10.2020
SK28.10.2020
SM28.10.2020
IE04.01.2021
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
CH31.01.2021
LI31.01.2021
IS28.02.2021
PT01.03.2021
Former [2021/52]AL28.10.2020
AT28.10.2020
CZ28.10.2020
DK28.10.2020
EE28.10.2020
ES28.10.2020
FI28.10.2020
HR28.10.2020
IT28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SI28.10.2020
SK28.10.2020
SM28.10.2020
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
CH31.01.2021
LI31.01.2021
IS28.02.2021
PT01.03.2021
Former [2021/50]AL28.10.2020
AT28.10.2020
CZ28.10.2020
DK28.10.2020
EE28.10.2020
ES28.10.2020
FI28.10.2020
HR28.10.2020
IT28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SI28.10.2020
SK28.10.2020
SM28.10.2020
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
IS28.02.2021
PT01.03.2021
Former [2021/48]AL28.10.2020
AT28.10.2020
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EE28.10.2020
ES28.10.2020
FI28.10.2020
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IT28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SK28.10.2020
SM28.10.2020
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
IS28.02.2021
PT01.03.2021
Former [2021/45]AL28.10.2020
AT28.10.2020
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EE28.10.2020
ES28.10.2020
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HR28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SK28.10.2020
SM28.10.2020
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
IS28.02.2021
PT01.03.2021
Former [2021/43]AT28.10.2020
CZ28.10.2020
DK28.10.2020
EE28.10.2020
ES28.10.2020
FI28.10.2020
HR28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SK28.10.2020
SM28.10.2020
LU04.01.2021
BG28.01.2021
NO28.01.2021
GR29.01.2021
IS28.02.2021
PT01.03.2021
Former [2021/40]AT28.10.2020
CZ28.10.2020
DK28.10.2020
EE28.10.2020
ES28.10.2020
FI28.10.2020
HR28.10.2020
LT28.10.2020
LV28.10.2020
MC28.10.2020
NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
SE28.10.2020
SK28.10.2020
SM28.10.2020
BG28.01.2021
NO28.01.2021
GR29.01.2021
IS28.02.2021
PT01.03.2021
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DK28.10.2020
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LV28.10.2020
NL28.10.2020
PL28.10.2020
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RS28.10.2020
SE28.10.2020
SK28.10.2020
SM28.10.2020
BG28.01.2021
NO28.01.2021
GR29.01.2021
IS28.02.2021
PT01.03.2021
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NL28.10.2020
PL28.10.2020
RO28.10.2020
RS28.10.2020
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SK28.10.2020
SM28.10.2020
BG28.01.2021
NO28.01.2021
GR29.01.2021
IS28.02.2021
PT01.03.2021
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BG28.01.2021
NO28.01.2021
GR29.01.2021
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BG28.01.2021
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Former [2021/23]AT28.10.2020
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Former [2021/20]FI28.10.2020
Documents cited:Search[I]WO2007088479  (RINAT NEUROSCIENCE CORP [US], et al) [I] 1-17 * See example 1, claims *
 [XI]  - LINDA LIN-YAN WU ET AL, "Huntingtin-associated Protein-1 Interacts with Pro-brain-derived Neurotrophic Factor and Mediates Its Transport and Release", JOURNAL OF BIOLOGICAL CHEMISTRY, (20091207), vol. 285, no. 8, doi:10.1074/jbc.M109.073197, ISSN 0021-9258, pages 5614 - 5623, XP055415200 [X] 8 * see § experimental procedures * [I] 1-7,9-17

DOI:   http://dx.doi.org/10.1074/jbc.M109.073197
International search[A]WO2008002572  (US GOV HEALTH & HUMAN SERV [US], et al);
 [A]WO2008074329  (NEURONICON APS [DK], et al);
 [X]  - YANG, LONGQIU., "Regulation of brain-derived neurotrophic factor and its precursor on pain''.", CHINESE DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, (20101115), XP055368797
 [A]  - LI, PINGPING ET AL., "Progress in pro-BDNF''.", CHN J FORENSIC MED, vol. 26, XP008183884
Examination   - AURORE QUIRIÉ ET AL, "Comparative Effect of Treadmill Exercise on Mature BDNF Production in Control versus Stroke Rats", PLOS ONE, (20120904), vol. 7, no. 9, doi:10.1371/journal.pone.0044218, page e44218, XP055498033

DOI:   http://dx.doi.org/10.1371/journal.pone.0044218
by applicantWO8909622
 EP0239400
 WO9007861
 WO9110741
 WO9402602
 WO9633735
    - GARBER K, "Painkiller Novel Fate of the mAbs Hangs in Balance", NAT BIOTECHNOL, vol. 2011, pages 173 - 174
    - SEIDEL M; LANE N, "Control of Arthritis Pain with Anti-Nerve-Growth Factor, Risk and Benefit", CURR RHEUMATOL REP, vol. 2012, pages 583 - 585
    - SCHIER, HUMAN ANTIBODY HYBRIDOMAS, (1996), vol. 7, pages 97 - 105
    - MALMBORG, IMMUNOL. METHODS, (1995), vol. 183, pages 7 - 13
    - DIXON WJ, "Efficient analysis of experimental observations", ANNU REV PHARMACOL TOXICOL, (1980), vol. 20, pages 441 - 62
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.