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Extract from the Register of European Patents

EP About this file: EP3177929

EP3177929 - METHOD OF SCREENING OF COMPOUNDS USING MEMBRANE STIM1 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  15.03.2019
Database last updated on 21.03.2026
FormerThe patent has been granted
Status updated on  06.04.2018
FormerGrant of patent is intended
Status updated on  28.01.2018
FormerRequest for examination was made
Status updated on  12.05.2017
FormerThe international publication has been made
Status updated on  09.12.2016
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): IS		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Université de Bretagne Occidentale (U.B.O.)
Site 1
3 rue des archives
29200 Brest / FR
For all designated states
INSERM
101, rue de Tolbiac
75654 Paris Cédex 13 / FR
For all designated states
Centre Hospitalier Régional et Universitaire de Brest
2 avenue Foch
29609 Brest Cedex / FR
[2017/24]
Inventor(s)01 / RENAUDINEAU, Yves
6 rue Pierre Semard
29200 Brest / FR
02 / MIGNEN, Olivier
42 Camen
29460 Logonna Daoulas / FR
03 / BURGOS, Miguel
C/Serreta 14, 5.
46130 Massamagrell (Valencia) / ES
04 / PERS, Jacques Olivier
10 rue Simon de Nantua
29200 Brest / FR
05 / FALI, Tinhinane
48 Logts Bt A N° 34
Rue Capitaine Si Abdullah
15000 Tizi-Ouzou / DZ
 [2017/24]
Representative(s)Novagraaf Technologies
Bâtiment O2
2, Rue Sarah Bernhardt
CS90017
92665 Asnières-sur-Seine Cedex / FR
[N/P]
Former [2017/24]Novagraaf Technologies
Bâtiment O2
2, rue Sarah Bernhardt
CS90017
92665 Asnières-sur-Seine Cedex / FR
Application number, filing date15744242.731.07.2015
[2017/24]
WO2015EP67615
Priority number, dateEP2014029023206.08.2014         Original published format: EP 14290232
[2017/24]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016020274
Date:11.02.2016
Language:EN
[2016/06]
Type: A1 Application with search report 
No.:EP3177929
Date:14.06.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 11.02.2016 takes the place of the publication of the European patent application.
[2017/24]
Type: B1 Patent specification 
No.:EP3177929
Date:09.05.2018
Language:EN
[2018/19]
Search report(s)International search report - published on:EP11.02.2016
ClassificationIPC:G01N33/564, G01N33/574, A61K39/00
[2017/24]
CPC:
G01N33/57505 (EP,US); A61K39/395 (EP,US); A61P35/00 (EP);
A61P35/02 (EP); A61P37/02 (EP); A61P43/00 (EP);
C07K16/28 (US); C07K16/2887 (US); G01N33/564 (EP,US);
A61K2039/507 (US); C07K2317/24 (US); C07K2317/34 (US);
G01N2500/04 (EP,US); G01N2500/10 (EP,US); G01N2800/104 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/24]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:VERFAHREN ZUM SCREENING VON VERBINDUNGEN UNTER VERWENDUNG VON MEMBRAN-STIM1[2018/06]
English:METHOD OF SCREENING OF COMPOUNDS USING MEMBRANE STIM1[2017/24]
French:PROCÉDÉ DE CRIBLAGE DE COMPOSÉS AU MOYEN D'UNE MEMBRANE STIM1[2018/06]
Former [2017/24]VERFAHREN ZUM SCREENING VON VERBINDUNGEN MIT MEMBRAN-STIM1
Former [2017/24]PROCÉDÉ DE CRIBLAGE DE COMPOSÉS AU MOYEN DE STIM1 MEMBRANAIRE
Entry into regional phase19.01.2017National basic fee paid 
19.01.2017Designation fee(s) paid 
19.01.2017Examination fee paid 
Examination procedure19.01.2017Examination requested  [2017/24]
19.01.2017Date on which the examining division has become responsible
18.09.2017Amendment by applicant (claims and/or description)
29.01.2018Communication of intention to grant the patent
27.03.2018Fee for grant paid
27.03.2018Fee for publishing/printing paid
27.03.2018Receipt of the translation of the claim(s)
Opposition(s)12.02.2019No opposition filed within time limit [2019/16]
Fees paidRenewal fee
24.07.2017Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU31.07.2015
AL09.05.2018
AT09.05.2018
CY09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
GR09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
MK09.05.2018
NL09.05.2018
PL09.05.2018
PT09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
TR09.05.2018
LU31.07.2018
MT31.07.2018
BG09.08.2018
NO09.08.2018
IS09.09.2018
[2020/32]
Former [2020/31]HU31.07.2015
AL09.05.2018
AT09.05.2018
CY09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
GR09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
MK09.05.2018
NL09.05.2018
PL09.05.2018
PT09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
TR09.05.2018
LU31.07.2018
MT31.07.2018
BG09.08.2018
NO09.08.2018
Former [2020/30]HU31.07.2015
AL09.05.2018
AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
GR09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
PT09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
TR09.05.2018
LU31.07.2018
MT31.07.2018
BG09.08.2018
NO09.08.2018
Former [2020/28]AL09.05.2018
AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
PT09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
TR09.05.2018
LU31.07.2018
MT31.07.2018
BG09.08.2018
NO09.08.2018
Former [2020/16]AL09.05.2018
AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
TR09.05.2018
LU31.07.2018
MT31.07.2018
BG09.08.2018
NO09.08.2018
Former [2020/08]AL09.05.2018
AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
LU31.07.2018
MT31.07.2018
BG09.08.2018
NO09.08.2018
Former [2019/51]AL09.05.2018
AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
LU31.07.2018
BG09.08.2018
NO09.08.2018
Former [2019/26]AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SI09.05.2018
SK09.05.2018
SM09.05.2018
LU31.07.2018
BG09.08.2018
NO09.08.2018
Former [2019/17]AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SK09.05.2018
SM09.05.2018
LU31.07.2018
BG09.08.2018
NO09.08.2018
Former [2019/15]AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
MC09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SK09.05.2018
SM09.05.2018
BG09.08.2018
NO09.08.2018
Former [2019/11]AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
IT09.05.2018
LT09.05.2018
LV09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SK09.05.2018
SM09.05.2018
BG09.08.2018
NO09.08.2018
Former [2019/10]AT09.05.2018
CZ09.05.2018
DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
LT09.05.2018
LV09.05.2018
NL09.05.2018
PL09.05.2018
RO09.05.2018
RS09.05.2018
SE09.05.2018
SK09.05.2018
BG09.08.2018
NO09.08.2018
Former [2019/09]DK09.05.2018
EE09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
LT09.05.2018
LV09.05.2018
NL09.05.2018
RS09.05.2018
SE09.05.2018
BG09.08.2018
NO09.08.2018
Former [2019/08]DK09.05.2018
ES09.05.2018
FI09.05.2018
HR09.05.2018
LT09.05.2018
LV09.05.2018
NL09.05.2018
RS09.05.2018
SE09.05.2018
BG09.08.2018
NO09.08.2018
Former [2018/52]ES09.05.2018
FI09.05.2018
HR09.05.2018
LT09.05.2018
LV09.05.2018
NL09.05.2018
RS09.05.2018
SE09.05.2018
BG09.08.2018
NO09.08.2018
Former [2018/51]ES09.05.2018
FI09.05.2018
HR09.05.2018
LT09.05.2018
LV09.05.2018
RS09.05.2018
SE09.05.2018
BG09.08.2018
NO09.08.2018
Former [2018/50]ES09.05.2018
FI09.05.2018
HR09.05.2018
LT09.05.2018
SE09.05.2018
BG09.08.2018
NO09.08.2018
Former [2018/49]ES09.05.2018
FI09.05.2018
LT09.05.2018
SE09.05.2018
BG09.08.2018
NO09.08.2018
Former [2018/47]ES09.05.2018
FI09.05.2018
LT09.05.2018
NO09.08.2018
Cited inInternational search[A]   GEORGE C. TSOKOS: "Calcium signaling in systemic lupus erythematosus lymphocytes and its therapeutic exploitation", ARTHRITIS & RHEUMATISM, vol. 58, no. 5, 1 May 2008 (2008-05-01), pages 1216 - 1219, XP055163670, ISSN: 0004-3591, DOI: 10.1002/art.23445 [A] 1-14

DOI:   http://dx.doi.org/10.1002/art.23445
 [A]   PERS J O ET AL: "Altered calcium signalling in B and T cells from Systemic Lupus Erythematosus patients is related to STIM1 expression", IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING LTD, GB, vol. 137, no. Suppl.1, 1 September 2012 (2012-09-01), pages 363, XP009181827, ISSN: 0019-2805 [A] 1-14 * the whole document *
 [A]   MUKHERJEE SREYA ET AL: "Stromal interaction molecules as important therapeutic targets in diseases with dysregulated calcium flux", BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR CELL RESEARCH, vol. 1843, no. 10, 25 March 2014 (2014-03-25), pages 2307 - 2314, XP029007393, ISSN: 0167-4889, DOI: 10.1016/J.BBAMCR.2014.03.019 [A] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bbamcr.2014.03.019
 [A]   MASOOD AISHA ET AL: "Targeted treatment for chronic lymphocytic leukemia", ONCOTARGETS AND THERAPY, vol. 4, 2011, pages 169 - 183, XP009181847, ISSN: 1178-6930 [A] 1-14 * the whole document *
 [Y]   Y. RENAUDINEAU: "Abnormal calcium influx in T and B lymphocytes from systemic lupus erythematosus patients is related to STIM-1 over-expression", ANNALS OF THE RHEUMATIC DISEASES, vol. 72, no. Suppl 1, 25 February 2013 (2013-02-25), pages A30 - A31, XP055160196, ISSN: 0003-4967, DOI: 10.1136/annrheumdis-2013-203219.2 [Y] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1136/annrheumdis-2013-203219.2
 [Y]   FALI T ET AL: "The calcium sensor stromal interaction molecule 1 (STIM1) controls regulatory B cell functions and its activity is impaired in Systemic Lupus Erythematosus patients", ANNALS OF THE RHEUMATIC DISEASES, BRITISH MEDICAL ASSOCIATION, LONDON, GB, vol. 73, no. Suppl. 1, 1 January 2014 (2014-01-01), pages A49 - A50, XP009185276, ISSN: 0003-4967 [Y] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1136/annrheumdis-2013-205124.113
 [A]   FATTAH ZOZIK ET AL: "Recent developments in the treatment of patients with systemic lupus erythematosus: focusing on biologic therapies", EXPERT OPINION ON BIOLOGICAL THERAPY, vol. 14, no. 3, March 2014 (2014-03-01), pages 311 - 326, XP009181848 [A] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1517/14712598.2014.871256
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.