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Extract from the Register of European Patents

EP About this file: EP3169809

EP3169809 - PRKC FUSIONS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.03.2021
Database last updated on 11.04.2026
FormerThe patent has been granted
Status updated on  27.03.2020
FormerGrant of patent is intended
Status updated on  21.11.2019
FormerExamination is in progress
Status updated on  23.02.2018
FormerRequest for examination was made
Status updated on  21.04.2017
FormerThe international publication has been made
Status updated on  07.02.2017
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Blueprint Medicines Corporation
38 Sidney Street, suite 200
Cambridge, MA 02139 / US
[2017/21]
Inventor(s)01 / STRANSKY, Nicolas
12 Lexington Street, 2
Charlestown, MA 02129 / US
02 / KIM, Joseph L.
20 Green Way
Wayland, MA 01778 / US
 [2017/21]
Representative(s)Finnegan Europe LLP
1 London Bridge
London SE1 9BG / GB
[2020/18]
Former [2017/21]Finnegan Europe LLP
16 Old Bailey
London EC4M 7EG / GB
Application number, filing date15753224.315.07.2015
[2017/21]
WO2015US40560
Priority number, dateUS201462025865P17.07.2014         Original published format: US 201462025865 P
[2017/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016011147
Date:21.01.2016
Language:EN
[2016/03]
Type: A1 Application with search report 
No.:EP3169809
Date:24.05.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 21.01.2016 takes the place of the publication of the European patent application.
[2017/21]
Type: B1 Patent specification 
No.:EP3169809
Date:29.04.2020
Language:EN
[2020/18]
Search report(s)International search report - published on:EP21.01.2016
ClassificationIPC:C12Q1/6886
[2019/43]
CPC:
C12Q1/6886 (EP,US); C07K16/30 (US); C12N15/1138 (US);
G01N33/5752 (US); C12Q2600/156 (EP,US)
Former IPC [2017/21]C12Q1/68
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/21]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:PRKC-FUSIONEN[2017/21]
English:PRKC FUSIONS[2017/21]
French:FUSIONS DE PRKC[2017/21]
Entry into regional phase07.02.2017National basic fee paid 
07.02.2017Designation fee(s) paid 
07.02.2017Examination fee paid 
Examination procedure07.02.2017Amendment by applicant (claims and/or description)
07.02.2017Examination requested  [2017/21]
07.02.2017Date on which the examining division has become responsible
21.02.2018Despatch of a communication from the examining division (Time limit: M06)
03.09.2018Reply to a communication from the examining division
21.11.2018Despatch of a communication from the examining division (Time limit: M06)
20.05.2019Reply to a communication from the examining division
22.11.2019Communication of intention to grant the patent
20.03.2020Fee for grant paid
20.03.2020Fee for publishing/printing paid
20.03.2020Receipt of the translation of the claim(s)
Opposition(s)01.02.2021No opposition filed within time limit [2021/14]
Fees paidRenewal fee
27.07.2017Renewal fee patent year 03
11.07.2018Renewal fee patent year 04
15.07.2019Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.07.2015
AL29.04.2020
AT29.04.2020
CY29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
MK29.04.2020
MT29.04.2020
NL29.04.2020
PL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SI29.04.2020
SK29.04.2020
SM29.04.2020
TR29.04.2020
IE15.07.2020
LU15.07.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
BE31.07.2020
CH31.07.2020
LI31.07.2020
IS29.08.2020
PT31.08.2020
[2022/32]
Former [2022/27]HU15.07.2015
AL29.04.2020
AT29.04.2020
CY29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
MT29.04.2020
NL29.04.2020
PL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SI29.04.2020
SK29.04.2020
SM29.04.2020
TR29.04.2020
IE15.07.2020
LU15.07.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
BE31.07.2020
CH31.07.2020
LI31.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/37]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
NL29.04.2020
PL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SI29.04.2020
SK29.04.2020
SM29.04.2020
IE15.07.2020
LU15.07.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
BE31.07.2020
CH31.07.2020
LI31.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/24]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
NL29.04.2020
PL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SI29.04.2020
SK29.04.2020
SM29.04.2020
LU15.07.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
BE31.07.2020
CH31.07.2020
LI31.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/20]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
NL29.04.2020
PL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SK29.04.2020
SM29.04.2020
LU15.07.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
CH31.07.2020
LI31.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/13]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
MC29.04.2020
NL29.04.2020
PL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SK29.04.2020
SM29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/10]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
NL29.04.2020
PL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SK29.04.2020
SM29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/09]AL29.04.2020
AT29.04.2020
CZ29.04.2020
DK29.04.2020
EE29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
IT29.04.2020
LT29.04.2020
LV29.04.2020
NL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SM29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/08]AL29.04.2020
DK29.04.2020
ES29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
NL29.04.2020
RO29.04.2020
RS29.04.2020
SE29.04.2020
SM29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/04]AL29.04.2020
FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
NL29.04.2020
RS29.04.2020
SE29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2021/01]FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
RS29.04.2020
SE29.04.2020
BG29.07.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/51]FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
RS29.04.2020
SE29.04.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/50]FI29.04.2020
HR29.04.2020
LT29.04.2020
LV29.04.2020
SE29.04.2020
NO29.07.2020
GR30.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/48]FI29.04.2020
LT29.04.2020
SE29.04.2020
NO29.07.2020
IS29.08.2020
PT31.08.2020
Former [2020/47]LT29.04.2020
NO29.07.2020
IS29.08.2020
Former [2020/46]IS29.08.2020
Cited inInternational search[XI] WO2014038887  (MACROGEN INC et al.) [X] 1-3,6-8,11-15,26-30,40-51,55,58-62,64,65,68-70 * paragraph [0176] - paragraph [0180]; figures 6, 41, 42; example 5; claims 14, 18, 19; table 50 * * paragraph [0159] - paragraph [0165] * * paragraph [0147] - paragraph [0149] *[I] 4,5,9,10,16-25,31-39,52-54,66,67,71,72
 [X] US2012171219  (ACEVEDO-DUNCAN MILDRED et al.) [X] 56-58,63 * claims 1, 12, 13 *
 [A] WO2013113942  (MAX PLANCK GESELLSCHAFT et al.) [A] 1-72 * claims 1, 2, 21, 42, 52 *
 [X]   PLASZCZYCA ANNA ET AL: "Fusions involving protein kinase C and membrane-associated proteins in benign fibrous histiocytoma", INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY, PERGAMON, GB, vol. 53, 8 April 2014 (2014-04-08), pages 475 - 481, XP029040270, ISSN: 1357-2725, DOI: 10.1016/J.BIOCEL.2014.03.027 [X] 1,6-8,11,26 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.biocel.2014.03.027
 [X]   JULIA A. BRIDGE ET AL: "Identification of a Novel, Recurrent SLC44A1-PRKCA Fusion in Papillary Glioneuronal Tumor", BRAIN PATHOLOGY., vol. 23, no. 2, 23 July 2012 (2012-07-23), CH, pages 121 - 128, XP055221005, ISSN: 1015-6305, DOI: 10.1111/j.1750-3639.2012.00612.x [X] 1,2,6-8,11,12,26 * the whole document *

DOI:   http://dx.doi.org/10.1111/j.1750-3639.2012.00612.x
 [X]   PHILIP J. STEPHENS ET AL: "Complex landscapes of somatic rearrangement in human breast cancer genomes", NATURE, vol. 462, no. 7276, 24 December 2009 (2009-12-24), pages 1005 - 1010, XP055064910, ISSN: 0028-0836, DOI: 10.1038/nature08645 [X] 1,6-8,11,12,26 * page 1009, column r, paragraph last; table 3 *

DOI:   http://dx.doi.org/10.1038/nature08645
 [XP]   NICOLAS STRANSKY ET AL: "The landscape of kinase fusions in cancer", NATURE COMMUNICATIONS, vol. 5, 10 September 2014 (2014-09-10), pages 4846, XP055223951, DOI: 10.1038/ncomms5846 [XP] 1-72 * page 4, column l, paragraph 2; figures 1, S9 *

DOI:   http://dx.doi.org/10.1038/ncomms5846
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