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Extract from the Register of European Patents

EP About this file: EP3191527

EP3191527 - GALACTOENGINEERED IMMUNOGLOBULIN 1 ANTIBODIES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.11.2020
Database last updated on 08.04.2026
FormerThe patent has been granted
Status updated on  13.12.2019
FormerGrant of patent is intended
Status updated on  24.07.2019
FormerExamination is in progress
Status updated on  02.02.2018
FormerRequest for examination was made
Status updated on  16.06.2017
FormerThe international publication has been made
Status updated on  24.01.2017
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[2017/29]
Inventor(s)01 / MALIK, Sebastian
Hauptstraße 15a
82387 Antdorf / DE
02 / REUSCH, Dietmar
Tessiner Strasse 113
81475 Muenchen / DE
03 / SCHNUERIGER, Alfred
Im Spitzacker 17
CH-4059 Basel / CH
04 / TEJADA, Max L.
121B Redding Road
Campbell California 95008 / US
05 / THOMANN, Marco
Loisachweg 1a
82547 Beuerberg / DE
 [2020/01]
Former [2017/29]01 / MALIK, Sebastian
Hauptstraße 15a
82387 Antdorf / DE
02 / REUSCH, Dietmar
Tessiner Strasse 113
81475 Muenchen / DE
03 / SCHNUERIGER, Alfred
Im Spitzacker 17
CH-4059 Basel / CH
04 / TEJADA, Max L.
121B Redding Road
Campbell California 95008 / US
05 / THOMANN, Marco
Westend 4
82377 Penzberg / DE
Representative(s)Burger, Alexander, et al
Roche Diagnostics GmbH
Patentabteilung
Nonnenwald 2
82377 Penzberg / DE
[2020/03]
Former [2017/29]Burger, Alexander, et al
Roche Diagnostics GmbH Patent Department (LPP.....6164) P.O.Box 11 52
82372 Penzberg / DE
Application number, filing date15759788.104.09.2015
[2017/29]
WO2015EP70285
Priority number, dateEP2014018420110.09.2014         Original published format: EP 14184201
US201462095912P23.12.2014         Original published format: US 201462095912 P
[2017/29]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016037947
Date:17.03.2016
Language:EN
[2016/11]
Type: A1 Application with search report 
No.:EP3191527
Date:19.07.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 17.03.2016 takes the place of the publication of the European patent application.
[2017/29]
Type: B1 Patent specification 
No.:EP3191527
Date:15.01.2020
Language:EN
[2020/03]
Search report(s)International search report - published on:EP17.03.2016
ClassificationIPC:C07K16/32, A61P35/00
[2017/29]
CPC:
C07K16/32 (EP,CN,US); A61P35/00 (EP); C12P21/005 (US);
C07K2317/24 (US); C07K2317/41 (EP,CN,US); C07K2317/52 (US);
C07K2317/732 (EP,CN,US); C07K2317/92 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/29]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:DURCH IN-VITRO-GALAKTOENGINEERING HERGESTELLTE IMMUNGLOBULIN-1-ANTIKÖRPER[2020/02]
English:GALACTOENGINEERED IMMUNOGLOBULIN 1 ANTIBODIES[2017/29]
French:ANTICORPS 1 D'IMMUNOGLOBULINE GALACTOSYNTHÉTISÉE IN VITRO[2020/02]
Former [2017/29]GALACTOMANIPULIERTE IMMUNGLOBULIN-1-ANTIKÖRPER
Former [2017/29]ANTICORPS DE TYPE IMMUNOGLOBULINES 1 GALACTO-MODIFIÉS
Entry into regional phase10.04.2017National basic fee paid 
10.04.2017Designation fee(s) paid 
10.04.2017Examination fee paid 
Examination procedure22.03.2016Request for preliminary examination filed
International Preliminary Examining Authority: EP
24.01.2017Date on which the examining division has become responsible
10.04.2017Examination requested  [2017/29]
24.10.2017Amendment by applicant (claims and/or description)
01.02.2018Despatch of a communication from the examining division (Time limit: M06)
23.07.2018Reply to a communication from the examining division
07.12.2018Despatch of a communication from the examining division (Time limit: M04)
18.02.2019Observations by third parties
11.04.2019Reply to a communication from the examining division
25.07.2019Communication of intention to grant the patent
26.11.2019Fee for grant paid
26.11.2019Fee for publishing/printing paid
26.11.2019Receipt of the translation of the claim(s)
Divisional application(s)EP19175629.5  / EP3567056
Opposition(s)16.10.2020No opposition filed within time limit [2020/52]
Fees paidRenewal fee
11.09.2017Renewal fee patent year 03
11.09.2018Renewal fee patent year 04
11.09.2019Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU04.09.2015
AL15.01.2020
AT15.01.2020
CY15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
MC15.01.2020
MK15.01.2020
MT15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
TR15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
[2022/31]
Former [2022/30]HU04.09.2015
AL15.01.2020
AT15.01.2020
CY15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
MC15.01.2020
MT15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
TR15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
Former [2022/27]HU04.09.2015
AT15.01.2020
CY15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
MC15.01.2020
MT15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
TR15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
Former [2021/37]AT15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
MC15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
IE04.09.2020
LU04.09.2020
BE30.09.2020
Former [2021/36]AT15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
MC15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
LU04.09.2020
BE30.09.2020
Former [2021/27]AT15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
MC15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
LU04.09.2020
Former [2021/23]AT15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
MC15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
Former [2021/10]AT15.01.2020
CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
IT15.01.2020
LT15.01.2020
LV15.01.2020
NL15.01.2020
PL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SI15.01.2020
SK15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
Former [2020/50]CZ15.01.2020
DK15.01.2020
EE15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
LT15.01.2020
LV15.01.2020
NL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SK15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
Former [2020/49]CZ15.01.2020
DK15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
LT15.01.2020
LV15.01.2020
NL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SK15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
Former [2020/48]DK15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
LT15.01.2020
LV15.01.2020
NL15.01.2020
RO15.01.2020
RS15.01.2020
SE15.01.2020
SM15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
Former [2020/47]DK15.01.2020
ES15.01.2020
FI15.01.2020
HR15.01.2020
LT15.01.2020
LV15.01.2020
NL15.01.2020
RS15.01.2020
SE15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
Former [2020/40]FI15.01.2020
HR15.01.2020
LV15.01.2020
NL15.01.2020
RS15.01.2020
SE15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
IS15.05.2020
PT07.06.2020
Former [2020/39]FI15.01.2020
HR15.01.2020
LV15.01.2020
NL15.01.2020
RS15.01.2020
SE15.01.2020
BG15.04.2020
NO15.04.2020
GR16.04.2020
PT07.06.2020
Former [2020/38]FI15.01.2020
HR15.01.2020
LV15.01.2020
NL15.01.2020
RS15.01.2020
SE15.01.2020
NO15.04.2020
GR16.04.2020
PT07.06.2020
Former [2020/37]FI15.01.2020
HR15.01.2020
LV15.01.2020
NL15.01.2020
RS15.01.2020
SE15.01.2020
NO15.04.2020
PT07.06.2020
Former [2020/36]FI15.01.2020
NL15.01.2020
RS15.01.2020
NO15.04.2020
PT07.06.2020
Former [2020/35]FI15.01.2020
NL15.01.2020
NO15.04.2020
Former [2020/33]NL15.01.2020
Cited inInternational search[X] WO2008083150  (CENTOCOR INC et al.)
 [X] WO9730087  (GLAXO GROUP LTD et al.)
 [X] FR2861080  (LAB FRANCAIS DU FRACTIONNEMENT et al.) [X] 1,3,6,13 * example -; table 1 *
 [X] WO2013021279  (LFB BIOTECHNOLOGIES et al.) [X] 8,9,14,17,18,21,22 * page 30, li 23;; example - *
 [X]   DAMIAN HOUDE ET AL: "Post-translational modifications differentially affect IgG1 conformation and receptor binding", MOLECULAR & CELLULAR PROTEOMICS : MCP, 1 August 2010 (2010-08-01), United States, pages 1716 - 1728, XP055169032, Retrieved from the Internet [retrieved on 20150212], DOI: 10.1074/mcp.M900540-MCP200

DOI:   http://dx.doi.org/10.1074/mcp.M900540-MCP200
 [XY]   SHINKAWA T ET AL: "The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 278, no. 5, 31 January 2003 (2003-01-31), pages 3466 - 3473, XP002355427, ISSN: 0021-9258, DOI: 10.1074/JBC.M210665200 [X] 1,2,4,13-15,17,18,21,22 * figure 1B; table I *[Y] 1-23

DOI:   http://dx.doi.org/10.1074/jbc.M210665200
other  ANONYMOUS: "Afucosylated monoclonal antibodies", WIKIPEDIA, THE FREE ENCYCLOPEDIA, 8 December 2018 (2018-12-08), XP055566770, Retrieved from the Internet
   ANONYMOUS: "PNGase F", WIKIPEDIA, THE FREE ENCYCLOPEDIA, XP03042018, Retrieved from the Internet
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.