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Extract from the Register of European Patents

EP About this file: EP3332019

EP3332019 - PROCESS FOR THE IN VIVO PRODUCTION OF RNA IN A HOST CELL [Right-click to bookmark this link]
Former [2018/24]PROCESS FOR THEIN VIVO
[2019/32]
StatusNo opposition filed within time limit
Status updated on  23.10.2020
Database last updated on 11.04.2026
FormerThe patent has been granted
Status updated on  15.11.2019
FormerGrant of patent is intended
Status updated on  15.07.2019
FormerExamination is in progress
Status updated on  01.03.2019
FormerRequest for examination was made
Status updated on  11.05.2018
FormerThe international publication has been made
Status updated on  18.02.2017
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
CureVac AG
Paul-Ehrlich-Str. 15
72076 Tübingen / DE
[2018/24]
Inventor(s)01 / SCHMID, Andreas
Franz-Xaver-Mezler-Str. 12
72488 Sigmaringen / DE
02 / STROBEL, Isabel
Heidelweg 1
91189 Gustenfelden / DE
03 / EBER, Fabian Johannes
Beim Kupferhammer 25/1
72070 Tübingen / DE
 [2019/51]
Former [2018/24]01 / SCHMID, Andreas
In der Vorstadt 10
72488 Sigmaringen / DE
02 / STROBEL, Isabel
Heidelweg 1
91189 Gustenfelden / DE
03 / EBER, Fabian Johannes
Beim Kupferhammer 25/1
72070 Tübingen / DE
Representative(s)Lasar, Andrea Gisela
Maiwald GmbH
Elisenhof
Elisenstraße 3
80335 München / DE
[N/P]
Former [2018/24]Lasar, Andrea Gisela
Maiwald Patentanwalts- und
Rechtsanwaltsgesellschaft mbH
Elisenhof
Elisenstraße 3
80335 München / DE
Application number, filing date15760098.207.08.2015
[2018/24]
WO2015EP68310
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017025120
Date:16.02.2017
Language:EN
[2017/07]
Type: A1 Application with search report 
No.:EP3332019
Date:13.06.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 16.02.2017 takes the place of the publication of the European patent application.
[2018/24]
Type: B1 Patent specification 
No.:EP3332019
Date:18.12.2019
Language:EN
[2019/51]
Search report(s)International search report - published on:EP16.02.2017
ClassificationIPC:C12P19/34, C12N15/10, C12N15/67
[2018/24]
CPC:
C12P19/34 (EP,US); C12N15/67 (US); C12N15/10 (US);
C12N15/70 (US); C12N2310/12 (US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/24]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:VERFAHREN ZUR IN-VIVO-PRODUKTION VON RNA IN EINER WIRTSZELLE[2019/32]
English:PROCESS FOR THE IN VIVO PRODUCTION OF RNA IN A HOST CELL[2019/32]
French:PROCÉDÉ POUR LA PRODUCTION IN VIVO D'ARN DANS UNE CELLULE HÔTE[2019/32]
Former [2018/24]IN-VIVO-VERFAHREN
Former [2018/24]PROCESS FOR THEIN VIVO
Former [2018/24]PROCÉDÉ POUR LA PRODUCTIONIN VIVO
Entry into regional phase07.03.2018National basic fee paid 
07.03.2018Designation fee(s) paid 
07.03.2018Examination fee paid 
Examination procedure07.03.2018Examination requested  [2018/24]
07.03.2018Date on which the examining division has become responsible
05.09.2018Amendment by applicant (claims and/or description)
05.03.2019Despatch of a communication from the examining division (Time limit: M04)
14.06.2019Reply to a communication from the examining division
16.07.2019Communication of intention to grant the patent
08.11.2019Fee for grant paid
08.11.2019Fee for publishing/printing paid
08.11.2019Receipt of the translation of the claim(s)
Divisional application(s)EP19216087.7  / EP3699288
Opposition(s)21.09.2020No opposition filed within time limit [2020/48]
Fees paidRenewal fee
26.04.2018Renewal fee patent year 03
24.08.2018Renewal fee patent year 04
28.08.2019Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
07.03.201803   M06   Fee paid on   26.04.2018
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU07.08.2015
AL18.12.2019
CY18.12.2019
CZ18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
MK18.12.2019
MT18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
TR18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
LU07.08.2020
[2022/32]
Former [2022/27]HU07.08.2015
AL18.12.2019
CY18.12.2019
CZ18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
MT18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
TR18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
LU07.08.2020
Former [2021/20]AL18.12.2019
CZ18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
LU07.08.2020
Former [2021/18]AL18.12.2019
CZ18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2021/10]AL18.12.2019
CZ18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
PL18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/51]AL18.12.2019
CZ18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/47]AL18.12.2019
CZ18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/40]AL18.12.2019
CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/37]AL18.12.2019
CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
SK18.12.2019
SM18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
PT13.05.2020
Former [2020/36]AL18.12.2019
CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
PT13.05.2020
Former [2020/35]AL18.12.2019
CZ18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RO18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/32]AL18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/25]FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
RS18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/23]FI18.12.2019
LT18.12.2019
LV18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/22]FI18.12.2019
LT18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
Former [2020/21]NO18.03.2020
Cited inInternational search[A] WO2007144508  (UNIV PARIS DESCARTES et al.)
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DOI:   http://dx.doi.org/10.1111/j.1574-6968.2008.01205.x
 [X]   JUOZAS AA IURKUS ET AL: "Heterologous production of active ribonuclease inhibitor in Escherichia coli by redox state control and chaperonin coexpression", MICROBIAL CELL FACTORIES, vol. 10, no. 1, 65, 8 August 2011 (2011-08-08), BIOMED CENTRAL, LONDON, NL, pages 1 - 11, XP021105373, ISSN: 1475-2859, DOI: 10.1186/1475-2859-10-65

DOI:   http://dx.doi.org/10.1186/1475-2859-10-65
 [AD]   NELISSEN FRANK H T ET AL: "Fast production of homogeneous recombinant RNA--towards large-scale production of RNA.", NUCLEIC ACIDS RESEARCH, vol. 40, no. 13, E102, July 2012 (2012-07-01), pages 1 - 12, XP002746282, ISSN: 1362-4962

DOI:   http://dx.doi.org/10.1093/nar/gks292
 [A]   LIU YAMEI ET AL: "DNAzyme-mediated recovery of small recombinant RNAs from a 5S rRNA-derived chimera expressed in Escherichia coli.", BMC BIOTECHNOLOGY, vol. 10, 85, 2010, pages 1 - 9, XP002746283, ISSN: 1472-6750

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 [A]   PONCHON LUC ET AL: "A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold.", NATURE PROTOCOLS 2009, vol. 4, no. 6, 2009, pages 947 - 959, XP002747452, ISSN: 1750-2799

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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.