blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP3122893

EP3122893 - L-2-HYDROXYGLUTARATE AND STRESS INDUCED METABOLISM [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.04.2022
Database last updated on 06.11.2024
FormerThe patent has been granted
Status updated on  30.04.2021
FormerGrant of patent is intended
Status updated on  14.12.2020
FormerExamination is in progress
Status updated on  18.05.2019
FormerRequest for examination was made
Status updated on  30.12.2016
FormerThe international publication has been made
Status updated on  16.11.2016
Most recent event   Tooltip13.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 16.10.2024  [2024/42]
Applicant(s)For all designated states
Memorial Sloan Kettering Cancer Center
1275 York Avenue
New York, NY 10065 / US
[2017/05]
Inventor(s)01 / INTLEKOFER, Andrew M.
504 E 63rd Street
Apt. 12L
New York, New York 10065 / US
02 / THOMPSON, Craig B.
247 E 71st Street
New York, New York 10021 / US
 [2017/05]
Representative(s)Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB
Ganghoferstraße 68 B
80339 München / DE
[2021/22]
Former [2017/05]Schiweck, Weinzierl & Koch
European Patent Attorneys
Landsberger Straße 98
80339 München / DE
Application number, filing date15768552.027.03.2015
[2017/05]
WO2015US23038
Priority number, dateUS201461972091P28.03.2014         Original published format: US 201461972091 P
[2017/05]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015148950
Date:01.10.2015
Language:EN
[2015/39]
Type: A1 Application with search report 
No.:EP3122893
Date:01.02.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 01.10.2015 takes the place of the publication of the European patent application.
[2017/05]
Type: B1 Patent specification 
No.:EP3122893
Date:02.06.2021
Language:EN
[2021/22]
Search report(s)International search report - published on:US01.10.2015
(Supplementary) European search report - dispatched on:EP14.11.2017
ClassificationIPC:C12Q1/32, C12Q1/68, G01N33/48
[2017/05]
CPC:
C12Q1/32 (EP,US); A61K31/711 (EP,US); A61P11/00 (EP);
A61P11/06 (EP); A61P31/00 (EP); A61P35/00 (EP);
A61P9/00 (EP); A61P9/10 (EP); G01N33/5091 (EP,US);
G01N2500/10 (EP,US); G01N2800/7038 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/05]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:L-2-HYDROXYGLUTARAT UND STRESSINDUZIERTER METABOLISMUS[2017/05]
English:L-2-HYDROXYGLUTARATE AND STRESS INDUCED METABOLISM[2017/05]
French:MÉTABOLISME INDUIT PAR STRESS ET L-2-HYDROXYGLUTARATE[2017/05]
Entry into regional phase26.10.2016National basic fee paid 
26.10.2016Search fee paid 
26.10.2016Designation fee(s) paid 
26.10.2016Examination fee paid 
Examination procedure26.10.2016Examination requested  [2017/05]
26.10.2016Date on which the examining division has become responsible
11.06.2018Amendment by applicant (claims and/or description)
22.05.2019Despatch of a communication from the examining division (Time limit: M06)
22.11.2019Reply to a communication from the examining division
15.12.2020Communication of intention to grant the patent
26.04.2021Fee for grant paid
26.04.2021Fee for publishing/printing paid
26.04.2021Receipt of the translation of the claim(s)
Opposition(s)03.03.2022No opposition filed within time limit [2022/19]
Fees paidRenewal fee
10.03.2017Renewal fee patent year 03
13.03.2018Renewal fee patent year 04
13.03.2019Renewal fee patent year 05
12.03.2020Renewal fee patent year 06
12.03.2021Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.03.2015
AL02.06.2021
AT02.06.2021
CY02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
IT02.06.2021
LT02.06.2021
LV02.06.2021
MC02.06.2021
MK02.06.2021
MT02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SI02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
[2024/42]
Former [2024/22]HU27.03.2015
AL02.06.2021
AT02.06.2021
CY02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
IT02.06.2021
LT02.06.2021
LV02.06.2021
MC02.06.2021
MK02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SI02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2024/20]HU27.03.2015
AL02.06.2021
AT02.06.2021
CY02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
IT02.06.2021
LT02.06.2021
LV02.06.2021
MC02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SI02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2024/18]HU27.03.2015
AL02.06.2021
AT02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
IT02.06.2021
LT02.06.2021
LV02.06.2021
MC02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SI02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2022/47]AL02.06.2021
AT02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
IT02.06.2021
LT02.06.2021
LV02.06.2021
MC02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SI02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2022/36]AL02.06.2021
AT02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
IT02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SI02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2022/29]AL02.06.2021
AT02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SI02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2022/26]AL02.06.2021
AT02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2022/21]AT02.06.2021
CZ02.06.2021
DK02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2022/10]AT02.06.2021
CZ02.06.2021
EE02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
IS02.10.2021
PT04.10.2021
Former [2022/09]AT02.06.2021
CZ02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RO02.06.2021
RS02.06.2021
SE02.06.2021
SK02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
PT04.10.2021
Former [2022/08]AT02.06.2021
CZ02.06.2021
ES02.06.2021
FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RS02.06.2021
SE02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
Former [2022/07]AT02.06.2021
FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
NL02.06.2021
PL02.06.2021
RS02.06.2021
SE02.06.2021
SM02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
Former [2021/52]FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
PL02.06.2021
RS02.06.2021
SE02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
Former [2021/51]FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
RS02.06.2021
SE02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
Former [2021/49]FI02.06.2021
HR02.06.2021
LT02.06.2021
LV02.06.2021
SE02.06.2021
BG02.09.2021
NO02.09.2021
GR03.09.2021
Former [2021/47]FI02.06.2021
LT02.06.2021
BG02.09.2021
Former [2021/46]FI02.06.2021
LT02.06.2021
Documents cited:Search[A]WO2004046729  (UNIV LEICESTER [GB], et al) [A] 1-3,5,14,15 * the whole document *;
 [X]WO2013075065  (SLOAN KETTERING INST CANCER [US]) [X] 1-3,5,14,15 * par 0059-0061, 00117-00119, 00146; cl 1-35. *;
 [A]  - FRANK G. SCHAAP ET AL, "Mutations in the Isocitrate Dehydrogenase Genes IDH1 and IDH2 in Tumors", ADVANCES IN ANATOMIC PATHOLOGY, (20130101), vol. 20, no. 1, doi:10.1097/PAP.0b013e31827b654d, ISSN 1072-4109, pages 32 - 38, XP055124935 [A] 1-3,5,14,15 * the whole document *

DOI:   http://dx.doi.org/10.1097/PAP.0b013e31827b654d
International search[Y]US2012202883  (HAI YAN [US], et al) [Y] 51/50/48* ; claims 15, 23, 25; paragraphs [0054], [0062] *;
 [XY]  - RAKHEJA, D et al., "Papillary Thyroid Carcinoma Shows Elevated Levels of 2-Hydroxyglutarate", Tumor Biology, (20110000), vol. 32, pages 325 - 333, XP055228019 [X] 1-2, 3/1-2, 5/2, 48, 50/48 * ; abstract; figures 2-3; pages 327-329, 332 * [Y] 51/50/48

DOI:   http://dx.doi.org/10.1007/s13277-010-0125-6
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.