blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

Italy joins the Federated Register

Click here for more information on the Federated Register.

2025-06-12

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register User Manual
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP3204400

EP3204400 - 17A,21-DIESTERS OF CORTEXOLONE FOR USE IN THE TREATMENT OF TUMORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.10.2019
Database last updated on 08.04.2026
FormerThe patent has been granted
Status updated on  09.11.2018
FormerGrant of patent is intended
Status updated on  05.11.2018
FormerRequest for examination was made
Status updated on  06.10.2018
FormerGrant of patent is intended
Status updated on  05.06.2018
FormerRequest for examination was made
Status updated on  14.07.2017
FormerThe international publication has been made
Status updated on  26.04.2017
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Cosmo Technologies Ltd
Riverside II
Sir John Rogerson's Quay
Dublin 2 / IE
[2017/33]
Inventor(s)01 / GERLONI, Mara
2933 Ariane Drive
San Diego, California CA 92117 / US
 [2017/33]
Representative(s)FRKelly
Waterways House
Grand Canal Quay
Dublin D02 PD39 / IE
[N/P]
Former [2018/50]FRKelly
27 Clyde Road
Dublin D04 F838 / IE
Former [2017/33]Hally, Anna-Louise
FRKelly
27 Clyde Road
Dublin D04 F838 / IE
Application number, filing date15778634.407.10.2015
[2017/33]
WO2015EP73172
Priority number, dateEP2014018806308.10.2014         Original published format: EP 14188063
[2017/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016055533
Date:14.04.2016
Language:EN
[2016/15]
Type: A1 Application with search report 
No.:EP3204400
Date:16.08.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 14.04.2016 takes the place of the publication of the European patent application.
[2017/33]
Type: B1 Patent specification 
No.:EP3204400
Date:12.12.2018
Language:EN
[2018/50]
Search report(s)International search report - published on:EP14.04.2016
ClassificationIPC:C07J5/00, A61K31/573, A61P35/00
[2017/33]
CPC:
A61K31/573 (EP,CN,IL,KR,US); C07J5/0053 (EP,CN,IL,KR,US); A61K45/06 (IL,US);
A61K9/0019 (IL,US); A61K9/0053 (IL,US); A61P35/00 (EP,KR);
A61P35/04 (EP,KR); A61P43/00 (EP); A61P5/46 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/33]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:17ALPHA,21-DIESTER VON CORTODOXON ZUR VERWENDUNG BEI DER BEHANDLUNG VON TUMOREN[2018/24]
English:17A,21-DIESTERS OF CORTEXOLONE FOR USE IN THE TREATMENT OF TUMORS[2017/33]
French:17ALPHA, 21-DIESTERS DE CORTEXOLONE POUR UTILISATION DANS LE TRAITEMENT DE TUMEURS[2018/24]
Former [2017/33]17A,21-DIESTER VON CORTEXOLON ZUR VERWENDUNG BEI DER BEHANDLUNG VON TUMOREN
Former [2017/33]17A,21-DIESTERS DE CORTELOXONE POUR UNE UTILISATION DANS LE TRAITEMENT DE TUMEURS
Entry into regional phase26.04.2017National basic fee paid 
26.04.2017Designation fee(s) paid 
26.04.2017Examination fee paid 
Examination procedure26.04.2017Examination requested  [2017/33]
26.04.2017Date on which the examining division has become responsible
30.11.2017Amendment by applicant (claims and/or description)
06.06.2018Communication of intention to grant the patent
05.10.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
05.10.2018Fee for grant paid
05.10.2018Fee for publishing/printing paid
05.11.2018Information about intention to grant a patent
05.11.2018Receipt of the translation of the claim(s)
Divisional application(s)EP18198653.0  / EP3456330
Opposition(s)13.09.2019No opposition filed within time limit [2019/47]
Request for further processing for:Loss of rights: Claims
20.12.2017Request for further processing filed
20.12.2017Full payment received (date of receipt of payment)
Request granted
15.01.2018Decision despatched
Fees paidRenewal fee
31.07.2017Renewal fee patent year 03
26.10.2018Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL12.12.2018
CY12.12.2018
MK12.12.2018
MT12.12.2018
SM12.12.2018
IS12.04.2019
[2022/31]
Former [2021/34]AL12.12.2018
CY12.12.2018
MT12.12.2018
SM12.12.2018
IS12.04.2019
Former [2021/26]AL12.12.2018
CY12.12.2018
SM12.12.2018
IS12.04.2019
Former [2019/39]AL12.12.2018
SM12.12.2018
IS12.04.2019
Former [2019/37]AL12.12.2018
SM12.12.2018
Former [2019/26]AL12.12.2018
Cited inInternational search[AD]   GIUSEPPE CELASCOA ET AL: "Pharmacological Profile of 9,11-Dehydrocortexolone 17[alpha]-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity", ARZNEIMITTEL FORSCHUNG. DRUG RESEARCH, ECV EDITIO CANTOR VERLAG, AULENDORF, DE, vol. 55, no. 10, 1 January 2005 (2005-01-01), pages 581 - 587, XP008175216, ISSN: 0004-4172, DOI: 10.1055/S-0031-1296908 [AD] 1-48 * page 582; table 1 * * abstract *

DOI:   http://dx.doi.org/10.1055/s-0031-1296908
 [A]   FERRABOSCHI P ET AL: "Lipase-catalyzed preparation of corticosteroid 17alpha-esters endowed with antiandrogenic activity", TETRAHEDRON LETTERS, PERGAMON, GB, vol. 49, no. 31, 28 July 2008 (2008-07-28), pages 4610 - 4612, XP022757401, ISSN: 0040-4039, [retrieved on 20080523], DOI: 10.1016/J.TETLET.2008.05.086 [A] 1-48 * page 4610, column 1, paragraph 1; compounds 3c, 3d * * page 4611; compounds 7c, 7d *

DOI:   http://dx.doi.org/10.1016/j.tetlet.2008.05.086
 [A]   PATRIZIA FERRABOSCHI ET AL: "A full conformational characterization of antiandrogen cortexolone-17[alpha]-propionate and related compounds through theoretical calculations and nuclear magnetic resonance spectroscopy", MEDCHEMCOMM, vol. 5, no. 7, 4 April 2014 (2014-04-04), United Kingdom, pages 904 - 914, XP055224342, ISSN: 2040-2503, DOI: 10.1039/C4MD00049H [A] 1-48 * page 904; compound 4 * * page 905, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1039/C4MD00049H
 [A]   DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; CUTLER, GORDON B., JR. ET AL: "11-Deoxycortisol: a glucocorticoid antagonist in vivo", XP002749428, retrieved from STN Database accession no. 1979:469056 [A] 1-48 * abstract *
 [A]   CUTLER, GORDON B., JR. ET AL: "11-Deoxycortisol: a glucocorticoid antagonist in vivo", ENDOCRINOLOGY , 104(6), 1839-44 CODEN: ENDOAO; ISSN: 0013-7227, 1979, DOI: 10.1210/ENDO-104-6-1839 10.1210/ENDO-104-6-1839
 [A]   TIMOTHY P. CORBISHLEY ET AL: "Androgen receptor in human normal and malignant pancreatic tissue and cell lines", CANCER, vol. 57, no. 10, 15 May 1986 (1986-05-15), pages 1992 - 1995, XP055174782, ISSN: 0008-543X, DOI: 10.1002/1097-0142(19860515)57:10<1992::AID-CNCR2820571019>3.0.CO;2-0 [A] 1-48 * abstract * * page 1994, column 2, paragraph 3 - page 1995, column 1, paragraph 3 *

DOI:   http://dx.doi.org/10.1002/1097-0142(19860515)57:10<1992::AID-CNCR2820571019>3.0.CO;2-0
 [A]   DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; PETERSON, R. E.: "Biliary excretion of neutral steroids in man", XP002736997, retrieved from STN Database accession no. 1966:87023 [A] 1-48 * abstract *
 [A]   PETERSON, R. E.: "Biliary excretion of neutral steroids in man", BILIARY SYSTEM, SYMP. NATO ADVAN. STUDY INST., NEWCASTLE-UPON-TYNE, ENGL. , 1963, 385-96, DISCUSSION 396-7, 1965
 [A]   JJ KEATING ET AL: "A prospective randomised controlled trial of tamoxifen and cyproterone acetate in pancreatic carcinoma", BRITISH JOURNAL OF CANCER, vol. 60, no. 5, 1 November 1989 (1989-11-01), pages 789 - 792, XP055174715, ISSN: 0007-0920, DOI: 10.1038/bjc.1989.361 [A] 1-48 * abstract *

DOI:   http://dx.doi.org/10.1038/bjc.1989.361
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.